Incorporating concomitant medications into genome-wide analyses for the study of complex disease and drug response

Frontiers in Genetics

Volumn 7, Issue AUG, 2016, Pages

  Graham, Hillary T ^a   Rotroff, Daniel M ^a   Marvel, Skylar W ^a   Buse, John B ^b   Havener, Tammy M ^c   Wilson, Alyson G ^a   Wagner, Michael J ^c   Motsinger Reif, Alison A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNC Hamner Institute for Drug Safety Sciences   (United States)

Author keywords

Bioinformatics; Clinical trial; Drug response; Genomics; Precision medicine

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FENOFIBRATE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LISINOPRIL; LOOP DIURETIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEGLITINIDE; NITRATE; SULFONYLUREA;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG RESPONSE; FEMALE; FOLLOW UP; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MIDDLE AGED; PRESCRIPTION; PRINCIPAL COMPONENT ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

EID: 84988346525     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2016.00138     Document Type: Article

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