Reduced intracellular drug accumulation in drug-resistant leukemia cells is not only solely due to MDR-mediated efflux but also to decreased uptake

Frontiers in Oncology

Volumn 4, Issue OCT, 2014, Pages

  Pisco, Angela Oliveira ^a,b   Jackson, Dean Andrew ^b   Huang, Sui ^a,c  

^a INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

ABC transporters dependent drug resistance; Acute myeloid leukemia model; Cellular responses to anticancer drugs; Endocytosis related multi drug resistance; Novel mechanism of multi drug resistance

Indexed keywords

DOXORUBICIN; INSULIN; MULTIDRUG RESISTANCE PROTEIN 1; PROPIDIUM IODIDE; VINCRISTINE;

ARTICLE; CANCER CHEMOTHERAPY; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; DRUG TUMOR LEVEL; ENDOCYTOSIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HL 60 CELL LINE; HUMAN; HUMAN CELL; LEUKEMIA; PHENOTYPE; TUMOR RESISTANCE;

EID: 84988322497     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2014.00306     Document Type: Article

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