메뉴 건너뛰기




Volumn 43, Issue , 2017, Pages 49-55

Multidimensional NMR approaches towards highly resolved, sensitive and high-throughput quantitative metabolomics

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; DATA ACQUISITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 84988038669     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2016.08.004     Document Type: Review
Times cited : (69)

References (42)
  • 1
    • 84891801016 scopus 로고    scopus 로고
    • Multidimensional approaches to NMR-based metabolomics
    • This comprehensive review gives the reader a good overview of the possibilities offered by 2D NMR applied to metabolomics. This paper therefore acts as an excellent basis to familiarise with the different aspects of multidimensional NMR.
    • 1• Bingol, K., Brüschweiler, R., Multidimensional approaches to NMR-based metabolomics. Anal Chem 86 (2014), 47–57 This comprehensive review gives the reader a good overview of the possibilities offered by 2D NMR applied to metabolomics. This paper therefore acts as an excellent basis to familiarise with the different aspects of multidimensional NMR.
    • (2014) Anal Chem , vol.86 , pp. 47-57
    • Bingol, K.1    Brüschweiler, R.2
  • 3
    • 77949779562 scopus 로고    scopus 로고
    • Combined NMR and LC–MS analysis reveals the metabonomic changes in Salvia miltiorrhiza Bunge induced by water depletion
    • 3 Dai, H., Xiao, C., Liu, H., Tang, H., Combined NMR and LC–MS analysis reveals the metabonomic changes in Salvia miltiorrhiza Bunge induced by water depletion. J Proteome Res 9 (2010), 1460–1475.
    • (2010) J Proteome Res , vol.9 , pp. 1460-1475
    • Dai, H.1    Xiao, C.2    Liu, H.3    Tang, H.4
  • 5
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • 5 Beckonert, O., Keun, H.C., Ebbels, T.M.D., Bundy, J., Holmes, E., Lindon, J.C., Nicholson, J.K., Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc 2 (2007), 2692–2703.
    • (2007) Nat Protoc , vol.2 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.D.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6    Nicholson, J.K.7
  • 6
    • 0009566394 scopus 로고
    • 1 noise in high field NMR spectrometers
    • 1 noise in high field NMR spectrometers. J Magn Reson 100 (1992), 316–328.
    • (1992) J Magn Reson , vol.100 , pp. 316-328
    • Morris, G.A.1
  • 7
    • 84900466692 scopus 로고    scopus 로고
    • Quantitative 2D liquid-state NMR
    • 7 Giraudeau, P., Quantitative 2D liquid-state NMR. Magn Res Chem 52 (2014), 259–272.
    • (2014) Magn Res Chem , vol.52 , pp. 259-272
    • Giraudeau, P.1
  • 8
    • 79952182400 scopus 로고    scopus 로고
    • Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology
    • 8 Robinette, S.L., Ajredini, R., Rasheed, H., Zeinomar, A., Schroeder, F.C., Dossey, A.T., Edison, A.S., Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology. Anal Chem 83 (2011), 1649–1657.
    • (2011) Anal Chem , vol.83 , pp. 1649-1657
    • Robinette, S.L.1    Ajredini, R.2    Rasheed, H.3    Zeinomar, A.4    Schroeder, F.C.5    Dossey, A.T.6    Edison, A.S.7
  • 10
    • 84902821405 scopus 로고    scopus 로고
    • Evaluation of fast 2D NMR for metabolomics
    • 10 Le Guennec, A., Giraudeau, P., Caldarelli, S., Evaluation of fast 2D NMR for metabolomics. Anal Chem 86 (2014), 5946–5954.
    • (2014) Anal Chem , vol.86 , pp. 5946-5954
    • Le Guennec, A.1    Giraudeau, P.2    Caldarelli, S.3
  • 12
    • 26944471174 scopus 로고    scopus 로고
    • The next wave in metabolome analysis
    • 12 Nielsen, J., Oliver, S., The next wave in metabolome analysis. Trends Biotechnol 23 (2005), 544–546.
    • (2005) Trends Biotechnol , vol.23 , pp. 544-546
    • Nielsen, J.1    Oliver, S.2
  • 14
    • 84945490815 scopus 로고    scopus 로고
    • 2D-Cosy NMR spectroscopy as a quantitative tool in biological matrix: application to cyclodextrins
    • 14 Dufour, G., Evrard, B., de Tullio, P., 2D-Cosy NMR spectroscopy as a quantitative tool in biological matrix: application to cyclodextrins. AAPS J 17 (2015), 1501–1510.
    • (2015) AAPS J , vol.17 , pp. 1501-1510
    • Dufour, G.1    Evrard, B.2    de Tullio, P.3
  • 16
    • 79951533289 scopus 로고    scopus 로고
    • 0)
    • 13C HSQC spectra and the addition of an internal standard, this interesting strategy allows the quantification of metabolites without going through a calibration procedure or pre-identification of the metabolites before the acquisition.
    • 13C HSQC spectra and the addition of an internal standard, this interesting strategy allows the quantification of metabolites without going through a calibration procedure or pre-identification of the metabolites before the acquisition.
    • (2011) J Am Chem Soc , vol.133 , pp. 1662-1665
    • Hu, K.1    Westler, W.M.2    Markley, J.L.3
  • 17
    • 80055084216 scopus 로고    scopus 로고
    • 0 spectroscopy of thiocoraline in an extract from a sponge-derived Verrucosispora sp
    • 0 spectroscopy of thiocoraline in an extract from a sponge-derived Verrucosispora sp. J Nat Prod 74 (2011), 2295–2298.
    • (2011) J Nat Prod , vol.74 , pp. 2295-2298
    • Hu, K.1    Wyche, T.P.2    Bugni, T.S.3    Markley, J.L.4
  • 18
    • 84893872841 scopus 로고    scopus 로고
    • Metabolomics analysis identifies D-alanine–D-alanine ligase as the primary lethal target of D-cycloserine in mycobacteria
    • 18 Halouska, S., Fenton, R.J., Zinniel, D.K., Marshall, D.D., Barletta, R.G., Powers, R., Metabolomics analysis identifies D-alanine–D-alanine ligase as the primary lethal target of D-cycloserine in mycobacteria. J Proteome Res 13 (2014), 1065–1076.
    • (2014) J Proteome Res , vol.13 , pp. 1065-1076
    • Halouska, S.1    Fenton, R.J.2    Zinniel, D.K.3    Marshall, D.D.4    Barletta, R.G.5    Powers, R.6
  • 19
    • 84966400953 scopus 로고    scopus 로고
    • 13C NMR data in one go for tracking metabolites in vegetal extracts
    • In this communication, the authors present a novel NMR method for quantitative metabolomics, named QUantItative, Perfected and pUre shifted HSQC (QUIPU HSQC). The analytical performance of the method is discussed and its practical application to the quantification of metabolites in complex extracts of Arabidopsis thaliana is presented.
    • 13C NMR data in one go for tracking metabolites in vegetal extracts. Chem Commun 52 (2016), 6142–6145 In this communication, the authors present a novel NMR method for quantitative metabolomics, named QUantItative, Perfected and pUre shifted HSQC (QUIPU HSQC). The analytical performance of the method is discussed and its practical application to the quantification of metabolites in complex extracts of Arabidopsis thaliana is presented.
    • (2016) Chem Commun , vol.52 , pp. 6142-6145
    • Mauve, C.1    Khlifi, S.2    Gilard, F.3    Mouille, G.4    Farjon, J.5
  • 20
    • 84987932883 scopus 로고    scopus 로고
    • Fast n-dimensional data acquisition methods
    • J.C. Lindon G.E. Tranter D. Koppenaal edn 3 Elsevier
    • 20 Rouger, L., Gouilleux, B., Giraudeau, P., Fast n-dimensional data acquisition methods. Lindon, J.C., Tranter, G.E., Koppenaal, D., (eds.) Encyclopedia of Spectroscopy and Spectrometry, edn 3, 2016, Elsevier, 10.1016/B978-0-12-409547-2.12107-9.
    • (2016) Encyclopedia of Spectroscopy and Spectrometry
    • Rouger, L.1    Gouilleux, B.2    Giraudeau, P.3
  • 21
    • 0003007299 scopus 로고
    • Exponential sampling, an alternative method for sampling in two-dimensional NMR experiments
    • 21 Barna, J.C.J., Laue, E.D., Mayger, M.R., Skilling, J., Worrall, S.J.P., Exponential sampling, an alternative method for sampling in two-dimensional NMR experiments. J Magn Reson 73 (1987), 69–77.
    • (1987) J Magn Reson , vol.73 , pp. 69-77
    • Barna, J.C.J.1    Laue, E.D.2    Mayger, M.R.3    Skilling, J.4    Worrall, S.J.P.5
  • 22
    • 84945469484 scopus 로고    scopus 로고
    • Resolution-enhanced 2D NMR of complex mixtures by non-uniform sampling
    • 22 Le Guennec, A., Dumez, J.-N., Giraudeau, P., Caldarelli, S., Resolution-enhanced 2D NMR of complex mixtures by non-uniform sampling. Magn Res Chem 53 (2015), 913–920.
    • (2015) Magn Res Chem , vol.53 , pp. 913-920
    • Le Guennec, A.1    Dumez, J.-N.2    Giraudeau, P.3    Caldarelli, S.4
  • 24
    • 84904300550 scopus 로고    scopus 로고
    • Ultrafast 2D NMR: an emerging tool in analytical spectroscopy
    • 24 Giraudeau, P., Frydman, L., Ultrafast 2D NMR: an emerging tool in analytical spectroscopy. Annu Rev Anal Chem 7 (2014), 129–161.
    • (2014) Annu Rev Anal Chem , vol.7 , pp. 129-161
    • Giraudeau, P.1    Frydman, L.2
  • 25
    • 84945496465 scopus 로고    scopus 로고
    • Fast hybrid multi-dimensional NMR methods based on ultrafast 2D NMR
    • 25 Akoka, S., Giraudeau, P., Fast hybrid multi-dimensional NMR methods based on ultrafast 2D NMR. Magn Reson Chem 53 (2015), 986–994.
    • (2015) Magn Reson Chem , vol.53 , pp. 986-994
    • Akoka, S.1    Giraudeau, P.2
  • 26
    • 84941023055 scopus 로고    scopus 로고
    • Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR
    • This paper presents a practical application of ultrafast quantitative 2D NMR to the targeted quantification of metabolites in plant extracts. The authors could achieve the high-throughput quantification of major metabolites present in tomato fruit extracts, with a 5 min acquisition time per spectrum.
    • 26• Jézéquel, T., Deborde, C., Maucourt, M., Zhendre, V., Moing, A., Giraudeau, P., Absolute quantification of metabolites in tomato fruit extracts by fast 2D NMR. Metabolomics 11 (2015), 1231–1242 This paper presents a practical application of ultrafast quantitative 2D NMR to the targeted quantification of metabolites in plant extracts. The authors could achieve the high-throughput quantification of major metabolites present in tomato fruit extracts, with a 5 min acquisition time per spectrum.
    • (2015) Metabolomics , vol.11 , pp. 1231-1242
    • Jézéquel, T.1    Deborde, C.2    Maucourt, M.3    Zhendre, V.4    Moing, A.5    Giraudeau, P.6
  • 27
    • 84871344551 scopus 로고    scopus 로고
    • Fast determination of absolute metabolite concentrations by spatially encoded 2D NMR: application to breast cancer cell extracts
    • 27 Le Guennec, A., Tea, I., Antheaume, I., Martineau, E., Charrier, B., Pathan, M., Akoka, S., Giraudeau, P., Fast determination of absolute metabolite concentrations by spatially encoded 2D NMR: application to breast cancer cell extracts. Anal Chem 84 (2012), 10831–10837.
    • (2012) Anal Chem , vol.84 , pp. 10831-10837
    • Le Guennec, A.1    Tea, I.2    Antheaume, I.3    Martineau, E.4    Charrier, B.5    Pathan, M.6    Akoka, S.7    Giraudeau, P.8
  • 28
    • 79959194193 scopus 로고    scopus 로고
    • Deconvolution of two-dimensional NMR spectra by fast maximum likelihood reconstruction: application to quantitative metabolomics
    • 28 Chylla, R.A., Hu, K., Ellinger, J.J., Markley, J.L., Deconvolution of two-dimensional NMR spectra by fast maximum likelihood reconstruction: application to quantitative metabolomics. Anal Chem 83 (2011), 4871–4880.
    • (2011) Anal Chem , vol.83 , pp. 4871-4880
    • Chylla, R.A.1    Hu, K.2    Ellinger, J.J.3    Markley, J.L.4
  • 29
    • 79958767366 scopus 로고    scopus 로고
    • The application of micro-coil NMR probe technology to metabolomics of urine and serum
    • 29 Grimes, J.H., O'Connell, T.M., The application of micro-coil NMR probe technology to metabolomics of urine and serum. J Biomol NMR 49 (2011), 297–305.
    • (2011) J Biomol NMR , vol.49 , pp. 297-305
    • Grimes, J.H.1    O'Connell, T.M.2
  • 33
    • 84961233906 scopus 로고    scopus 로고
    • 2 hyperpolarization: application to natural extracts
    • This recent publication shows how the selective properties of the parahydrogen approach can be cleverly used to create a chemosensor, able to target otherwise overlapped analytes. This allowed the authors to perform the selective quantification of pyridine and pyrazine derivatives in roasted ground coffee, using a standard addition procedure and the 2D SEPP-HoSQC experiment, with a detection limit in the low-micromolar concentration range.
    • 2 hyperpolarization: application to natural extracts. Anal Chem 88 (2016), 3406–3412 This recent publication shows how the selective properties of the parahydrogen approach can be cleverly used to create a chemosensor, able to target otherwise overlapped analytes. This allowed the authors to perform the selective quantification of pyridine and pyrazine derivatives in roasted ground coffee, using a standard addition procedure and the 2D SEPP-HoSQC experiment, with a detection limit in the low-micromolar concentration range.
    • (2016) Anal Chem , vol.88 , pp. 3406-3412
    • Hermkens, N.K.J.1    Eshuis, N.2    van Weerdenburg, B.J.A.3    Feiters, M.C.4    Rutjes, F.P.J.T.5    Wijmenga, S.S.6    Tessari, M.7
  • 35
    • 84954384608 scopus 로고    scopus 로고
    • Single-scan multidimensional NMR analysis of mixtures at sub-millimolar concentrations by using SABRE hyperpolarization
    • In this publication, the authors describe the use of SABRE hyperpolarisation for obtaining, in a single scan, clean 2D COSY spectra of a mixture of multiple analytes, even at concentrations as low as 0.5 mM.
    • 35• Daniele, V., Legrand, F.-X., Berthault, P., Dumez, J.-N., Huber, G., Single-scan multidimensional NMR analysis of mixtures at sub-millimolar concentrations by using SABRE hyperpolarization. ChemPhysChem 16 (2015), 3413–3417 In this publication, the authors describe the use of SABRE hyperpolarisation for obtaining, in a single scan, clean 2D COSY spectra of a mixture of multiple analytes, even at concentrations as low as 0.5 mM.
    • (2015) ChemPhysChem , vol.16 , pp. 3413-3417
    • Daniele, V.1    Legrand, F.-X.2    Berthault, P.3    Dumez, J.-N.4    Huber, G.5
  • 36
    • 34249909508 scopus 로고    scopus 로고
    • Ultrafast two-dimensional nuclear magnetic resonance spectroscopy of hyperpolarized solutions
    • 36 Frydman, L., Blazina, D., Ultrafast two-dimensional nuclear magnetic resonance spectroscopy of hyperpolarized solutions. Nat Phys 3 (2007), 415–419.
    • (2007) Nat Phys , vol.3 , pp. 415-419
    • Frydman, L.1    Blazina, D.2
  • 37
    • 70349624332 scopus 로고    scopus 로고
    • Multiple ultrafast, broadband 2D NMR spectra of hyperpolarized natural products
    • 37 Giraudeau, P., Shrot, Y., Frydman, L., Multiple ultrafast, broadband 2D NMR spectra of hyperpolarized natural products. J Am Chem Soc 131 (2009), 13902–13903.
    • (2009) J Am Chem Soc , vol.131 , pp. 13902-13903
    • Giraudeau, P.1    Shrot, Y.2    Frydman, L.3
  • 38
    • 84938948134 scopus 로고    scopus 로고
    • Hyperpolarized NMR of plant and cancer cell extracts at natural abundance
    • 13C spectra of tomato extracts. Most importantly, it provides a promising application of D-DNP with single-scan UF HSQC on human breast cancer cell lines. This study therefore opens up the scope of possibilities for multidimensional NMR applied to natural extracts.
    • 13C spectra of tomato extracts. Most importantly, it provides a promising application of D-DNP with single-scan UF HSQC on human breast cancer cell lines. This study therefore opens up the scope of possibilities for multidimensional NMR applied to natural extracts.
    • (2015) Analyst , vol.140 , pp. 5860-5863
    • Dumez, J.-N.1    Milani, J.2    Vuichoud, B.3    Bornet, A.4    Lalande-Martin, J.5    Tea, I.6    Yon, M.7    Maucourt, M.8    Deborde, C.9    Moing, A.10
  • 39
    • 84939228243 scopus 로고    scopus 로고
    • Implementation and characterization of flow injection in dissolution dynamic nuclear polarization NMR spectroscopy
    • 39 Chen, H.-Y., Hilty, C., Implementation and characterization of flow injection in dissolution dynamic nuclear polarization NMR spectroscopy. ChemPhysChem 16 (2015), 2646–2652.
    • (2015) ChemPhysChem , vol.16 , pp. 2646-2652
    • Chen, H.-Y.1    Hilty, C.2
  • 41
    • 84886907350 scopus 로고    scopus 로고
    • Fast spatially encoded 3D NMR strategies for 13C-based metabolic flux analysis
    • 41 Boisseau, R., Charrier, B., Massou, S., Portais, J.-C., Akoka, S., Giraudeau, P., Fast spatially encoded 3D NMR strategies for 13C-based metabolic flux analysis. Anal Chem 85 (2013), 9751–9757.
    • (2013) Anal Chem , vol.85 , pp. 9751-9757
    • Boisseau, R.1    Charrier, B.2    Massou, S.3    Portais, J.-C.4    Akoka, S.5    Giraudeau, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.