Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment

Proteomics - Clinical Applications

Volumn 10, Issue 8, 2016, Pages 839-850

  Schubert, Peter ^a   Culibrk, Brankica ^a   Karwal, Simrath ^a   Goodrich, Raymond P ^b   Devine, Dana V ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Scientific and Clinical Affairs   (United States)

Author keywords

Blood platelets; Pathogen inactivation; Protein synthesis; Quantitative proteomics; Transfusion medicine; Translatome analyses

Indexed keywords

PROTEOME; PUROMYCIN; RIBOFLAVIN; THROMBOCYTE CONCENTRATE;

APHERESIS; ARTICLE; BLOOD BANK; BLOOD STORAGE; CYTOSKELETON; IMMUNOBLOTTING; IN VITRO STUDY; PATHOGEN REDUCTION SYSTEM; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEOMICS; THROMBOCYTE AGGREGATION; THROMBOCYTE METABOLISM; ULTRAVIOLET RADIATION; VALIDITY;

EID: 84987824824     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.201500139     Document Type: Article

References (41)

1. Devine, D. V., Serrano, K., The platelet storage lesion. Clin. Lab. Med. 2010, 30, 475–487.
2. Blajchman, M. A., Goldman, M., Baeza, F., Improving the bacteriological safety of platelet transfusions. Transfus. Med. Rev. 2004, 18, 11–24.
3. Brecher, M. E., Hay, S. N., Improving platelet safety: bacterial contamination of platelets. Curr. Hematol. Rep. 2004, 3, 121–127.
4. Salunkhe, V., van der Meer, P. F., de Korte, D., Seghatchian, J., Gutierrez, L., Development of blood transfusion product pathogen reduction treatments: a review of methods, current applications and demands. Transfus. Apher. Sci. 2015, 52, 19–34.
5. Schlenke, P., Pathogen inactivation technologies for cellular blood components: an update. Transfus. Med. Hemother. 2014, 41, 309–325.
6. Fast, L. D., DiLeone, G., Marschner, S., Inactivation of human white blood cells in platelet products after pathogen reduction technology treatment in comparison to gamma irradiation. Transfusion 2011, 51, 1397–1404.
7. Irsch, J., Lin, L., Pathogen inactivation of platelet and plasma blood components for transfusion using the INTERCEPT blood system. Transfus. Med. Hemother. 2011, 38, 19–31.
8. Seltsam, A., Muller, T. H., UVC irradiation for pathogen reduction of platelet concentrates and plasma. Transfus. Med. Hemother. 2011, 38, 43–54.
9. Kaiser-Guignard, J., Canellini, G., Lion, N., Abonnenc, M. et al., The clinical and biological impact of new pathogen inactivation technologies on platelet concentrates. Blood Rev. 2014, 28, 235–241.
10. van Marwijk Kooy, M., Akkerman, J. W., van Asbeck, S., Borghuis, L., van Prooijen, H. C., UVB radiation exposes fibrinogen binding sites on platelets by activating protein kinase C via reactive oxygen species. Br. J. Haematol. 1993, 83, 253–258.
11. Verhaar, R., Dekkers, D. W., De Cuyper, I. M., Ginsberg, M. H. et al., UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin alphaIIbbeta3. Blood 2008, 112, 4935–4939.
12. Prudent, M., D'Alessandro, A., Cazenave, J. P., Devine, D. V. et al., Proteome changes in platelets after pathogen inactivation—an interlaboratory consensus. Transfus. Med. Rev. 2014, 28, 72–83.
13. Schubert, P., Coupland, D., Culibrk, B., Goodrich, R. P., Devine, D. V., Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment. Transfusion 2013, 53, 3164–3173.
14. Schubert, P., Culibrk, B., Coupland, D., Scammell, K. et al., Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage. Transfusion 2012, 52, 397–408.
15. Thon, J. N., Schubert, P., Duguay, M., Serrano, K. et al., Comprehensive proteomic analysis of protein changes during platelet storage requires complementary proteomic approaches. Transfusion 2008, 48, 425–435.
16. Ross, P. L., Huang, Y. N., Marchese, J. N., Williamson, B. et al., Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol. Cell Proteomics 2004, 3, 1154–1169.
17. Aviner, R., Geiger, T., Elroy-Stein, O., Genome-wide identification and quantification of protein synthesis in cultured cells and whole tissues by puromycin-associated nascent chain proteomics (PUNCH-P). Nat. Protoc. 2014, 9, 751–760.
18. Cox, J., Mann, M., MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 2008, 26, 1367–1372.
19. Cox, J., Matic, I., Hilger, M., Nagaraj, N. et al., A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics. Nat. Protoc. 2009, 4, 698–705.
20. Thon, J. N., Montalvo, A., Patel-Hett, S., Devine, M. T. et al., Cytoskeletal mechanics of proplatelet maturation and platelet release. J. Cell Biol. 2010, 191, 861–874.
21. Abonnenc, M., Sonego, G., Crettaz, D., Aliotta, A. et al., In vitro study of platelet function confirms the contribution of the ultraviolet B (UVB) radiation in the lesions observed in riboflavin/UVB-treated platelet concentrates. Transfusion 2015, 55, 2219–2230.
22. Devine, D. V., Schubert, P., Proteomic applications in blood transfusion: working the jigsaw puzzle. Vox Sang 2011, 100, 84–91.
23. Queloz, P. A., Thadikkaran, L., Crettaz, D., Rossier, J. S. et al., Proteomics and transfusion medicine: future perspectives. Proteomics 2006, 6, 5605–5614.
24. Burkhart, J. M., Vaudel, M., Gambaryan, S., Radau, S. et al., The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood 2012, 120, e73–e82.
25. Hechler, B., Ohlmann, P., Chafey, P., Ravanat, C. et al., Preserved functional and biochemical characteristics of platelet components prepared with amotosalen and ultraviolet A for pathogen inactivation. Transfusion 2013, 53, 1187–1200.
26. Marrocco, C., D'Alessandro, A., Girelli, G., Zolla, L., Proteomic analysis of platelets treated with gamma irradiation versus a commercial photochemical pathogen reduction technology. Transfusion 2013, 53, 1808–1820.
27. Mohr, H., Steil, L., Gravemann, U., Thiele, T. et al., A novel approach to pathogen reduction in platelet concentrates using short-wave ultraviolet light. Transfusion 2009, 49, 2612–2624.
28. Prudent, M., Crettaz, D., Delobel, J., Tissot, J. D., Lion, N., Proteomic analysis of Intercept-treated platelets. J. Proteomics 2012, 76, 316–328.
29. Thiele, T., Sablewski, A., Iuga, C., Bakchoul, T. et al., Profiling alterations in platelets induced by Amotosalen/UVA pathogen reduction and gamma irradiation—a LC-ESI-MS/MS-based proteomics approach. Blood Transfus. 2012, 10, s63–70.
30. Liumbruno, G., D'Alessandro, A., Grazzini, G., Zolla, L., Blood-related proteomics. J. Proteomics 2010, 73, 483–507.
31. Elvers, M., RhoGAPs and Rho GTPases in platelets. Hamostaseologie 2015, 35. Epub ahead of print: http://dx.doi.org/10.5482/HAMO-14-09-0046
32. Jones, C. I., Tucker, K. L., Sasikumar, P., Sage, T. et al., Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. J. Thromb. Haemost. 2014, 12, 1342–1352.
33. Mangin, P. H., Receveur, N., Wurtz, V., David, T. et al., Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets. J. Thromb. Haemost. 2009, 7, 1550–1555.
34. Schubert, P., Thon, J. N., Walsh, G. M., Chen, C. H. et al., A signaling pathway contributing to platelet storage lesion development: targeting PI3-kinase-dependent Rap1 activation slows storage-induced platelet deterioration. Transfusion 2009, 49, 1944–1955.
35. Kieffer, N., Guichard, J., Farcet, J. P., Vainchenker, W., Breton-Gorius, J., Biosynthesis of major platelet proteins in human blood platelets. Eur. J. Biochem. 1987, 164, 189–195.
36. Handagama, P., Scarborough, R. M., Shuman, M. A., Bainton, D. F., Endocytosis of fibrinogen into megakaryocyte and platelet alpha-granules is mediated by alpha IIb beta 3 (glycoprotein IIb-IIIa). Blood 1993, 82, 135–138.
37. Harrison, P., Wilbourn, B., Debili, N., Vainchenker, W. et al., Uptake of plasma fibrinogen into the alpha granules of human megakaryocytes and platelets. J. Clin. Invest. 1989, 84, 1320–1324.
38. Weyrich, A. S., Lindemann, S., Tolley, N. D., Kraiss, L. W. et al., Change in protein phenotype without a nucleus: translational control in platelets. Semin. Thromb. Hemost. 2004, 30, 491–498.
39. Weyrich, A. S., Schwertz, H., Kraiss, L. W., Zimmerman, G. A., Protein synthesis by platelets: historical and new perspectives. J. Thromb. Haemost. 2009, 7, 241–246.
40. Mezzano, D., Matus, V., Saez, C. G., Pereira, J., Panes, O., Tissue factor storage, synthesis and function in normal and activated human platelets. Thromb. Res. 2008, 122 (Suppl 1), S31–S36.
41. Thon, J. N., Devine, D. V., Translation of glycoprotein IIIa in stored blood platelets. Transfusion 2007, 47, 2260–2270.