A signaling pathway contributing to platelet storage lesion development: Targeting PI3-kinase-dependent Rap1 activation slows storage-induced platelet deterioration

Transfusion

Volumn 49, Issue 9, 2009, Pages 1944-1955

  Schubert, Peter ^a   Thon, Jonathan N ^a   Walsh, Geraldine M ^a   Chen, Cindy H I ^a   Moore, Edwin D ^a   Devine, Dana V ^a   Kast, Juergen ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA2 INTEGRIN; GLYCOPROTEIN IIIA; PADGEM PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAP1 PROTEIN; TALIN;

ARTICLE; CELL METABOLISM; CELL VIABILITY; CONTROLLED STUDY; DEGRANULATION; HUMAN; HUMAN CELL; PLATELET STORAGE LESION; PROTEIN LOCALIZATION; PROTEOMICS; SIGNAL TRANSDUCTION; THROMBOCYTE ANOMALY; THROMBOCYTE FUNCTION; THROMBOCYTE PRESERVATION; THROMBOCYTE STRUCTURE; THROMBOCYTE TRANSFUSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOOD PLATELETS; BLOOD PRESERVATION; BLOTTING, WESTERN; CHROMONES; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MICROSCOPY, FLUORESCENCE; MORPHOLINES; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 69249177069     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2009.02224.x     Document Type: Article

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