Neuroprotective Role of MicroRNA-22 in a 6-Hydroxydopamine-Induced Cell Model of Parkinson’s Disease via Regulation of Its Target Gene TRPM7

Journal of Molecular Neuroscience

Volumn 60, Issue 4, 2016, Pages 445-452

  Yang, Chao Ping ^a   Zhang, Zhen Hua ^b   Zhang, Li Hua ^a   Rui, Han Chen ^a  

^a CANGZHOU CENTRAL HOSPITAL   (China)

^b Cangzhou Medical College   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; MICRORNA 22; MICRORNA 22 INHIBITOR; NEUROPROTECTIVE AGENT; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; UNCLASSIFIED DRUG; MICRORNA; MIRN22 MICRORNA, RAT; PROTEIN SERINE THREONINE KINASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM7 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PC12 CELL LINE; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; UPREGULATION; ANIMAL; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; HUMANS; MICRORNAS; NEURONS; OXIDOPAMINE; PARKINSON DISEASE; PC12 CELLS; PROTEIN-SERINE-THREONINE KINASES; RATS; TRPM CATION CHANNELS;

EID: 84986269048     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-016-0828-2     Document Type: Article

References (39)

1. Aarts M, Iihara K, Wei W-L, Xiong Z-G, Arundine M, Cerwinski W, MacDonald JF, Tymianski M (2003) A key role for TRPM7 channels in anoxic neuronal death. Cell 115:863–877
2. Alvarez-Erviti L, Seow Y, Schapira AH, Rodriguez-Oroz MC, Obeso JA, Cooper J (2013) Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson’s disease. Cell Death Dis 4:e545
3. Asrar S, Aarts M (2013) TRPM7, the cytoskeleton and neuronal death. Channels 7:6–16
4. Berenguer J, Herrera A, Vuolo L, Torroba B, Llorens F, Sumoy L, Pons S (2013) MicroRNA 22 regulates cell cycle length in cerebellar granular neuron precursors. Mol Cell Biol 33:2706–2717
5. Brichta L, Greengard P, Flajolet M (2013) Advances in the pharmacological treatment of Parkinson’s disease: targeting neurotransmitter systems. Trends Neurosci 36:543–554
6. Cheng B, Guo Y, Li C, Ji B, Pan Y, Chen J, Bai B (2014) Edaravone protected PC12 cells against MPP (+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression. J Neurol Sci 343:115–119
7. Cho HJ, Liu G, Jin SM, Parisiadou L, Xie C, Yu J, Sun L, Ma B, Ding J, Vancraenenbroeck R (2013) MicroRNA-205 regulates the expression of Parkinson’s disease-related leucine-rich repeat kinase 2 protein. Hum Mol Genet 22:608–620
8. Choi PS, Zakhary L, Choi W-Y, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH (2008) Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 57:41–55
9. Chong C-M, Zhou Z-Y, Razmovski-Naumovski V, Cui G-Z, Zhang L-Q, Sa F, Hoi P-M, Chan K, Lee SM-Y (2013a) Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish. Neurosci Lett 543:121–125
10. Chong CM, Zhou ZY, Razmovski-Naumovski V, Cui GZ, Zhang LQ, Sa F, Hoi PM, Chan K, Lee SM (2013b) Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish. Neurosci Lett 543:121–125
11. Cohen G, Heikkila RE (1974) The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents. J Biol Chem 249:2447–2452
12. de Mena L, Coto E, Cardo LF, Díaz M, Blázquez M, Ribacoba R, Salvador C, Pastor P, Samaranch L, Moris G (2010) Analysis of the micro-RNA-133 and PITX3 genes in Parkinson’s disease. Am J Med Genet B Neuropsychiatr Genet 153:1234–1239
13. Eacker SM, Dawson TM, Dawson VL (2009) Understanding microRNAs in neurodegeneration. Nat Rev Neurosci 10:837–841
14. Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102–114
15. Harraz MM, Dawson TM, Dawson VL (2011) MicroRNAs in Parkinson’s disease. J Chem Neuroanat 42:127–130
16. Hensley K, Maidt ML, Yu Z, Sang H, Markesbery WR, Floyd RA (1998) Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 18:8126–8132
17. Jeon BS, Jackson-Lewis V, Burke RE (1995) 6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death. Neurodegeneration 4:131–137
18. Jiang H, Tian S-L, Zeng Y, Li L-L, Shi J (2008) TrkA pathway (s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen–glucose deprivation. Brain Res Bull 76:124–130
19. Jovicic A, Zaldivar Jolissaint JF, Moser R, Silva Santos Mde F, Luthi-Carter R (2013a) MicroRNA-22 (miR-22) overexpression is neuroprotective via general anti-apoptotic effects and may also target specific Huntington’s disease-related mechanisms. PLoS One 8:e54222
20. Jovicic A, Zaldivar Jolissaint JF, Moser R, Silva Santos Mde F, Luthi-Carter R (2013b) MicroRNA-22 (miR-22) overexpression is neuroprotective via general anti-apoptotic effects and may also target specific Huntington’s disease-related mechanisms. PLoS One 8:17
21. Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E, Hannon G, Abeliovich A (2007) A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317:1220–1224
22. Liu L, Jiang Y, Zhang H, Greenlee AR, Yu R, Yang Q (2010) miR-22 functions as a micro-oncogene in transformed human bronchial epithelial cells induced by anti-benzo [a] pyrene-7, 8-diol-9, 10-epoxide. Toxicol in Vitro 24:1168–1175
23. Margis R, Rieder CR (2011) Identification of blood microRNAs associated to Parkinsonis disease. J Biotechnol 152:96–101
24. Margis R, Margis R, Rieder CR (2011) Identification of blood microRNAs associated to Parkinsońs disease. J Biotechnol 152:96–101
25. Miñones-Moyano E, Porta S, Escaramís G, Rabionet R, Iraola S, Kagerbauer B, Espinosa-Parrilla Y, Ferrer I, Estivill X, Martí E (2011) MicroRNA profiling of Parkinson’s disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Hum Mol Genet 20:3067–3078
26. Monteilh-Zoller MK, Hermosura MC, Nadler MJ, Scharenberg AM, Penner R, Fleig A (2003) TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol 121:49–60
27. Montell C, Birnbaumer L, Flockerzi V (2002) The TRP channels, a remarkably functional family. Cell 108:595–598
28. Mouradian MM (2012) MicroRNAs in Parkinson’s disease. Neurobiol Dis 46:279–284
29. Shi L, Chen J, Yang J, Pan T, Zhang S, Wang Z (2010) MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res 1352:255–264
30. Shinde SMS, Mohsen G, et al. (2015) Biofluid-based microRNA biomarkers for Parkinson’s disease: an overview and update. AIMS. Med Sci 2:15–25
31. Sun H-S, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP (2009) Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nat Neurosci 12:1300–1307
32. Tolleson CM, Fang JY (2013) Advances in the mechanisms of Parkinson’s disease. Discov Med 15:61–66
33. Tonelli DDP, Pulvers JN, Haffner C, Murchison EP, Hannon GJ, Huttner WB (2008) miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 135:3911–3921
34. Wang G, van der Walt JM, Mayhew G, Li Y-J, Züchner S, Scott WK, Martin ER, Vance JM (2008) Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of α-synuclein. Am J Hum Genet 82:283–289
35. Wei W-L, Sun H-S, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong Z-G, Jackson MF (2007) TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations. Proc Natl Acad Sci 104:16323–16328
36. Woodgate A, MacGibbon G, Walton M, Dragunow M (1999) The toxicity of 6-hydroxydopamine on PC12 and P19 cells. Brain Res Mol Brain Res 69:84–92
37. Yang J, Chen L, Yang J, Ding J, Li S, Wu H, Zhang J, Fan Z, Dong W, Li X (2014) MicroRNA-22 targeting CBP protects against myocardial ischemia–reperfusion injury through anti-apoptosis in rats. Mol Biol Rep 41:555–561
38. Ye Y, Perez-Polo JR, Qian J, Birnbaum Y (2011) The role of microRNA in modulating myocardial ischemia-reperfusion injury. Physiol Genomics 43:534–542
39. Zhang Z, Li G, Szeto SS, Chong CM, Quan Q, Huang C, Cui W, Guo B, Wang Y, Han Y, et al. (2015) Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease. Free Radic Biol Med 84:331–343