Parallel accumulation-serial fragmentation (PASEF): Multiplying sequencing speed and sensitivity by synchronized scans in a trapped ion mobility device

Journal of Proteome Research

Volumn 14, Issue 12, 2015, Pages 5378-5387

  Meier, Florian ^a   Beck, Scarlet ^a   Grassl, Niklas ^a   Lubeck, Markus ^b   Park, Melvin A ^b   Raether, Oliver ^b   Mann, Matthias ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b BRUKER DALTONIK GMBH   (Germany)

Author keywords

High resolution; Ion mobility; MS MS; Multiplexing; Peptide sequencing; Proteomics; Time of flight; TIMS

Indexed keywords

PROTEIN; PEPTIDE FRAGMENT; PROTEOME;

ARTICLE; FRAGMENTATION REACTION; ION MOBILITY SPECTROMETRY; PARALLEL ACCUMULATION SERIAL FRAGMENTATION; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEOMICS; QUADRUPOLE MASS SPECTROMETRY; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; TRAPPED ION MOBILITY SPECTROMETRY; VELOCITY; AMINO ACID SEQUENCE; CHEMISTRY; DEVICES; ELECTROSPRAY MASS SPECTROMETRY; EQUIPMENT DESIGN; HELA CELL LINE; HUMAN; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PROCEDURES; STATISTICS AND NUMERICAL DATA;

AMINO ACID SEQUENCE; EQUIPMENT DESIGN; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEOME; PROTEOMICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84986182823     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00932     Document Type: Article

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