-
1
-
-
85059682251
-
Drugmakers' pricing power remains strong
-
Published July 14, 2016. Accessed July 14, 2016
-
Walker J. Drugmakers' pricing power remains strong.Wall Street Journal. http://www.wsj.com /articles/drugmakers-pricing-power-remains -strong-1468488601. Published July 14, 2016. Accessed July 14, 2016.
-
Wall Street Journal.
-
-
Walker, J.1
-
2
-
-
84877244628
-
-
Medicine use and spending in the US: a review of 2015 and outlook to 2020 Published April 2016. Accessed August 7, 2016
-
IMS Institute for Healthcare Informatics. Medicine use and spending in the US: a review of 2015 and outlook to 2020. https://morningconsult .com/wp-content/uploads/2016/04/IMS-Institute -US-Drug-Spending-2015.pdf. Published April 2016. Accessed August 7, 2016.
-
IMS Institute for Healthcare Informatics
-
-
-
3
-
-
84938690786
-
National health expenditure projections, 2014-24: Spending growth faster than recent trends
-
Keehan SP, Cuckler GA, Sisko AM, et al. National health expenditure projections, 2014-24: spending growth faster than recent trends. Health Aff (Millwood). 2015;34(8):1407-1417.
-
(2015)
Health Aff (Millwood)
, vol.34
, Issue.8
, pp. 1407-1417
-
-
Keehan, S.P.1
Cuckler, G.A.2
Sisko, A.M.3
-
4
-
-
84997468073
-
Observations on trends in prescription drug spending
-
Published March 8, 2016 Accessed July 13, 2016
-
Observations on trends in prescription drug spending. ASPE Issue Brief. https://aspe.hhs.gov /sites/default/files/pdf/187586/Drugspending.pdf. Published March 8, 2016. Accessed July 13, 2016.
-
ASPE Issue Brief
-
-
-
5
-
-
84997094679
-
Prescription drug's sizeable share of health spending
-
Published December 13, Accessed July 13, 2016
-
Altman D. Prescription drug's sizeable share of health spending.Washington Post. http://blogs.wsj .com/washwire/2015/12/13/prescription-drugs -sizable-share-of-health-spending/. Published December 13, 2015. Accessed July 13, 2016.
-
(2015)
Washington Post.
-
-
Altman, D.1
-
6
-
-
84997340726
-
-
Department of Health and Human Services. Health, United States, 2015 Published May 2016. Accessed July 13, 2016
-
Department of Health and Human Services. Health, United States, 2015. http://www.cdc.gov /nchs/data/hus/hus15.pdf#094. Published May 2016. Accessed July 13, 2016.
-
-
-
-
7
-
-
24944490530
-
A comparison of brand-name drug prices between Canadian-based Internet pharmacies and major US drug chain pharmacies
-
Quon BS, Firszt R, Eisenberg MJ. A comparison of brand-name drug prices between Canadian-based Internet pharmacies and major US drug chain pharmacies. Ann Intern Med. 2005;143 (6):397-403.
-
(2005)
Ann Intern Med.
, vol.143
, Issue.6
, pp. 397-403
-
-
Quon, B.S.1
Firszt, R.2
Eisenberg, M.J.3
-
8
-
-
84996638270
-
-
Organisation for Economic Co-operation and Development Paris, France: OECD Publishing
-
Organisation for Economic Co-operation and Development. Health at a Glance 2015: OECD Indicators. Paris, France: OECD Publishing, 2015.
-
(2015)
Health at A Glance 2015: OECD Indicators
-
-
-
9
-
-
84997404140
-
Exclusive-transatlantic divide: How US pays three times more for drugs
-
Published October 12, Accessed July 13, 2016
-
Hirschler B. Exclusive-transatlantic divide: how US pays three times more for drugs. Reuters. http: //www.reuters.com/article/us-pharmaceuticals -usa-comparison-idUSKCN0S61KU20151012. Published October 12, 2015. Accessed July 13, 2016.
-
(2015)
Reuters.
-
-
Hirschler, B.1
-
10
-
-
85047331628
-
The US pays a lot more for top drugs than other countries
-
Published December 18, Accessed July 13, 2016
-
Langreth R, Migliozzi B, Gokhale K. The US pays a lot more for top drugs than other countries. Bloomberg Business. http://www.bloomberg.com /graphics/2015-drug-prices/. Published December 18, 2015. Accessed July 13, 2016.
-
(2015)
Bloomberg Business
-
-
Langreth, R.1
Migliozzi, B.2
Gokhale, K.3
-
11
-
-
84877964537
-
Higher US branded drug prices and spending compared to other countriesmay stem partly from quick uptake of new drugs
-
Kanavos P, Ferrario A, Vandoros S, Anderson GF. Higher US branded drug prices and spending compared to other countriesmay stem partly from quick uptake of new drugs. Health Aff (Millwood). 2013;32(4):753-761.
-
(2013)
Health Aff (Millwood).
, vol.32
, Issue.4
, pp. 753-761
-
-
Kanavos, P.1
Ferrario, A.2
Vandoros, S.3
Anderson, G.F.4
-
12
-
-
32644435800
-
The implications of choice: Prescribing generic or preferred pharmaceuticals improves medication adherence for chronic conditions
-
Shrank WH, Hoang T, Ettner SL, et al. The implications of choice: prescribing generic or preferred pharmaceuticals improves medication adherence for chronic conditions. Arch Intern Med. 2006;166(3):332-337.
-
(2006)
Arch Intern Med.
, vol.166
, Issue.3
, pp. 332-337
-
-
Shrank, W.H.1
Hoang, T.2
Ettner, S.L.3
-
13
-
-
84924862927
-
Cost-effectiveness of novel regimens for the treatment of hepatitis C virus
-
Najafzadeh M, Andersson K, Shrank WH, et al. Cost-effectiveness of novel regimens for the treatment of hepatitis C virus. Ann Intern Med. 2015;162(6):407-419.
-
(2015)
Ann Intern Med.
, vol.162
, Issue.6
, pp. 407-419
-
-
Najafzadeh, M.1
Andersson, K.2
Shrank, W.H.3
-
15
-
-
84997426035
-
-
Generic Pharmaceutical Association Published November 3, Accessed July 13, 2016
-
Generic Pharmaceutical Association. Generic drug savings in the US. http://www.gphaonline.org /media/wysiwyg/PDF/GPhA-Savings-Report-2015 .pdf. Published November 3, 2015. Accessed July 13, 2016.
-
(2015)
Generic Drug Savings in the US.
-
-
-
16
-
-
77952520148
-
-
Published March 2015. Accessed July 31, 2016
-
Express Scripts. The 2015 drug trend report. http://lab.express-scripts.com/lab/drug-trend -report. Published March 2015. Accessed July 31, 2016.
-
(2015)
Drug Trend Report
-
-
-
17
-
-
84873892594
-
-
Bureau of Labor Statistics Published January 5, Accessed July 13, 2016
-
Bureau of Labor Statistics. Databases, tables and calculators by subject. http://data.bls.gov /timeseries/CUUR0000SAM?output-view=pct-12mths. Published January 5, 2016. Accessed July 13, 2016.
-
(2016)
Databases, Tables and Calculators by Subject
-
-
-
18
-
-
84997404176
-
-
New York Times. Published May 25, Accessed July 13, 2016
-
Fisher LM. Company news; new enzyme by Genzyme is approved. New York Times. http://www .nytimes.com/1994/05/25/business/company -news-new-enzyme-by-genzyme-is-approved.html. Published May 25, 1994. Accessed July 13, 2016.
-
(1994)
Company News; New Enzyme by Genzyme Is Approved
-
-
Fisher, L.M.1
-
19
-
-
84997254587
-
-
Boston Globe. Published September 2. Accessed July 13, 2016
-
Weisman R. New Genzyme pill will cost patients 310,250. Boston Globe. https://www.bostonglobe .com/business/2014/09/02/new-genzyme-pill -treat-rare-gaucher-disease-will-cost-patients-year /5thkIb587nKi7zRAb9GgxM/story.html. Published September 2, 2014. Accessed July 13, 2016.
-
(2014)
New Genzyme Pill Will Cost Patients 310,250
-
-
Weisman, R.1
-
20
-
-
85010369862
-
Drug pricing trends for orally administered anticancer medications reimbursed by commercial health plans, 2000-2014
-
Dusetzina SB. Drug pricing trends for orally administered anticancer medications reimbursed by commercial health plans, 2000-2014. JAMA Oncol. 2016;2(7):960-961.
-
(2016)
JAMA Oncol.
, vol.2
, Issue.7
, pp. 960-961
-
-
Dusetzina, S.B.1
-
21
-
-
84962573972
-
Expenditures and prices of antihyperglycemic medications in the United States: 2002-2013
-
Hua X, Carvalho N, Tew M, Huang ES, Herman WH, Clarke P. Expenditures and prices of antihyperglycemic medications in the United States: 2002-2013. JAMA. 2016;315(13): 1400-1402.
-
(2016)
JAMA.
, vol.315
, Issue.13
, pp. 1400-1402
-
-
Hua, X.1
Carvalho, N.2
Tew, M.3
Huang, E.S.4
Herman, W.H.5
Clarke, P.6
-
22
-
-
84977623151
-
-
New York Times. Published September 20. Accessed July 13, 2016
-
Pollack A. Drug goes from 13.50 a tablet to 750, overnight. New York Times. http://www .nytimes.com/2015/09/21/business/a-huge -overnight-increase-in-a-drugs-price-raisesprotests. html?-r=0. Published September 20, 2015. Accessed July 13, 2016.
-
(2015)
Drug Goes from 13.50 A Tablet to 750, Overnight
-
-
Pollack, A.1
-
23
-
-
85048735467
-
-
Market Watch. Published September 21, Accessed July 13, 2016
-
O'Brien E. Why drug prices remain insanely high and 6 things you can do to save. Market Watch. http://www.marketwatch.com/story/six-tips-for -fighting-rising-prescription-drug-costs-2015-09-15. Published September 21, 2015. Accessed July 13, 2016.
-
(2015)
Why Drug Prices Remain Insanely High and 6 Things You Can Do to Save
-
-
O'Brien, E.1
-
24
-
-
84877961747
-
Health care cost containment strategies used in four other high-income countries hold lessons for the United States
-
Stabile M, Thomson S, Allin S, et al. Health care cost containment strategies used in four other high-income countries hold lessons for the United States. Health Aff (Millwood). 2013;32(4): 643-652.
-
(2013)
Health Aff (Millwood).
, vol.32
, Issue.4
, pp. 643-652
-
-
Stabile, M.1
Thomson, S.2
Allin, S.3
-
26
-
-
84955303274
-
Cancer drugs in 16 European countries, Australia, and New Zealand: A cross-country price comparison study
-
Vogler S, Vitry A, Babar ZU. Cancer drugs in 16 European countries, Australia, and New Zealand: a cross-country price comparison study. Lancet Oncol. 2016;17(1):39-47.
-
(2016)
Lancet Oncol.
, vol.17
, Issue.1
, pp. 39-47
-
-
Vogler, S.1
Vitry, A.2
Babar, Z.U.3
-
27
-
-
80055038797
-
-
Directorate-General for Internal Policies Accessed July 13, 2016
-
Directorate-General for Internal Policies. Differences in costs of an access to pharmaceutical products in the EU. 2011. http://www.europarl .europa.eu/RegData/etudes/etudes/join/2011 /451481/IPOL-ENVI-ET(2011)451481-EN.pdf. Accessed July 13, 2016.
-
(2011)
Differences in Costs of An Access to Pharmaceutical Products in the EU.
-
-
-
28
-
-
84941711856
-
Probing our moral values in health care: The pricing of specialty drugs
-
Reinhardt U. Probing our moral values in health care: the pricing of specialty drugs. JAMA. 2015;314 (10):981-982.
-
(2015)
JAMA.
, vol.314
, Issue.10
, pp. 981-982
-
-
Reinhardt, U.1
-
29
-
-
72649106871
-
-
21 CFR 314.108: code of federal regulations title 21
-
Food and Drug Administration. 21 CFR 314.108: code of federal regulations title 21.
-
Food and Drug Administration
-
-
-
30
-
-
84997058494
-
-
US Government Publishing Office 42 USC-+ - 262(k)(7)(A): regulation of biological products
-
US Government Publishing Office. 42 USC-+ - 262(k)(7)(A): regulation of biological products.
-
-
-
-
31
-
-
84997394966
-
-
USC 154(a)( 2): contents and term of patent: provisional rights
-
USC 154(a)(2): contents and term of patent: provisional rights.
-
-
-
-
32
-
-
84997211233
-
-
USC 102, 103: conditions for patentability: novelty and non-obvious subject matter
-
USC 102, 103: conditions for patentability: novelty and non-obvious subject matter.
-
-
-
-
33
-
-
78951480503
-
Pharmaceutical innovation in the 21st century: New drug approvals in the first decade, 2000-2009
-
Kaitin KI, DiMasi JA. Pharmaceutical innovation in the 21st century: new drug approvals in the first decade, 2000-2009. Clin Pharmacol Ther. 2011;89 (2):183-188.
-
(2011)
Clin Pharmacol Ther.
, vol.89
, Issue.2
, pp. 183-188
-
-
Kaitin, K.I.1
DiMasi, J.A.2
-
35
-
-
84905270591
-
Impact of pediatric exclusivity on drug labeling and demonstrations of efficacy
-
Wharton GT, Murphy MD, Avant D, et al. Impact of pediatric exclusivity on drug labeling and demonstrations of efficacy. Pediatrics. 2014;134(2): e512-e518.
-
(2014)
Pediatrics.
, vol.134
, Issue.2
, pp. e512-e518
-
-
Wharton, G.T.1
Murphy, M.D.2
Avant, D.3
-
36
-
-
84997167154
-
-
Food and Drug Administration Published May, Accessed July 13, 2016
-
Food and Drug Administration. Pediatric exclusivity granted. http://www.fda.gov/downloads /Drugs/DevelopmentApprovalProcess /DevelopmentResources/UCM505429.pdf. Published May 2016. Accessed July 13, 2016.
-
(2016)
Pediatric Exclusivity Granted
-
-
-
37
-
-
84923894594
-
Variations in time of market exclusivity among top-selling prescription drugs in the United States
-
Wang B, Liu J, Kesselheim AS. Variations in time of market exclusivity among top-selling prescription drugs in the United States. JAMA Intern Med. 2015;175(4):635-637.
-
(2015)
JAMA Intern Med.
, vol.175
, Issue.4
, pp. 635-637
-
-
Wang, B.1
Liu, J.2
Kesselheim, A.S.3
-
38
-
-
84997420989
-
Updated trends in US brand-name and generic drug competition
-
Grabowski H, Long G, Mortimer R, Boyo A. Updated trends in US brand-name and generic drug competition. J Med Econ. 2016;20:1-9.
-
(2016)
J Med Econ.
, vol.20
, pp. 1-9
-
-
Grabowski, H.1
Long, G.2
Mortimer, R.3
Boyo, A.4
-
39
-
-
0041632148
-
The dual effects of intellectual property regulations: Within- and between-patent competition in the US pharmaceuticals industry
-
Lichtenberg FR, Philipson T. The dual effects of intellectual property regulations: within- and between-patent competition in the US pharmaceuticals industry. J Law Econ. 2002;45: 643-672.
-
(2002)
J Law Econ.
, vol.45
, pp. 643-672
-
-
Lichtenberg, F.R.1
Philipson, T.2
-
40
-
-
84997485164
-
Special sale price: Docs divided over discount on Abb Vie hepatitis C drug
-
Published December 22, Accessed July 13, 2016
-
Loftus P. Special sale price: docs divided over discount on Abb Vie hepatitis C drug. Wall Street Journal. http://blogs.wsj.com/pharmalot/2014/12 /22/special-sale-price-docs-divided-over-discount -on-abbvie-hepatitis-c-drug/. Published December 22, 2014. Accessed July 13, 2016.
-
(2014)
Wall Street Journal.
-
-
Loftus, P.1
-
41
-
-
84929613226
-
How state and federal policies as well as advances in genome science contribute to the high cost of cancer drugs
-
Ramsey SD. How state and federal policies as well as advances in genome science contribute to the high cost of cancer drugs. Health Aff (Millwood). 2015;34(4):571-575.
-
(2015)
Health Aff (Millwood).
, vol.34
, Issue.4
, pp. 571-575
-
-
Ramsey, S.D.1
-
42
-
-
79957778475
-
Randomized head-to-head comparison of pitavastatin, atorvastatin, and rosuvastatin for safety and efficacy (quantity and quality of LDL): The PATROL trial
-
PATROL Trial Investigators
-
Saku K, Zhang B, Noda K; PATROL Trial Investigators. Randomized head-to-head comparison of pitavastatin, atorvastatin, and rosuvastatin for safety and efficacy (quantity and quality of LDL): the PATROL trial. Circ J. 2011;75(6): 1493-1505.
-
(2011)
Circ J.
, vol.75
, Issue.6
, pp. 1493-1505
-
-
Saku, K.1
Zhang, B.2
Noda, K.3
-
43
-
-
84997240506
-
-
Consumer Reports. Published November, Accessed July 13, 2016
-
Consumer Reports. Knowing when prescription prices are high and how to avoid overspending. http://www.consumerreports.org /cro/2012/11/where-high-drug-costs-hide/index .htm. Published November 2012. Accessed July 13, 2016.
-
(2012)
Knowing When Prescription Prices Are High and How to Avoid Overspending
-
-
-
44
-
-
84997240519
-
-
Managed Care Published November, Accessed July 13, 2016
-
Reinke T; Managed Care. Free statins disrupt pharmacy benefits plans. http://www .managedcaremag.com/archives/2012/11/free -statins-disrupt-pharmacy-benefit-plans. Published November 2012. Accessed July 13, 2016.
-
(2012)
Free Statins Disrupt Pharmacy Benefits Plans
-
-
Reinke, T.1
-
45
-
-
0036026762
-
Do pharmaceutical sales respond to scientific evidence?
-
Azoulay P. Do pharmaceutical sales respond to scientific evidence? J Econ Manage Strategy. 2002; 11(4):551-594.
-
(2002)
J Econ Manage Strategy.
, vol.11
, Issue.4
, pp. 551-594
-
-
Azoulay, P.1
-
46
-
-
84997286513
-
-
Bureau of Consumer Protection Washington, DC: US Government Printing Office
-
Bureau of Consumer Protection. Staff Report to the Federal Trade Commission. Washington, DC: US Government Printing Office; 1979.
-
(1979)
Staff Report to the Federal Trade Commission
-
-
-
47
-
-
34848840928
-
Physician awareness of drug cost: A systematic review
-
Allan GM, Lexchin J, Wiebe N. Physician awareness of drug cost: a systematic review. PLoS Med. 2007;4(9):e283.
-
(2007)
PLoS Med.
, vol.4
, Issue.9
, pp. e283
-
-
Allan, G.M.1
Lexchin, J.2
Wiebe, N.3
-
48
-
-
78650358304
-
-
Federal Trade Commission Published January, Accessed July 13, 2016
-
Federal Trade Commission. Pay-for-delay: how drug company pay-offs cost consumers billions. https://www.ftc.gov/sites/default/files/documents /reports/pay-delay-how-drug-company-pay-offs -cost-consumers-billions-federal-trade -commission-staff-study/100112payfordelayrpt.pdf. Published January 2010. Accessed July 13, 2016.
-
(2010)
Pay-for-delay: How Drug Company Pay-offs Cost Consumers Billions
-
-
-
49
-
-
71949085389
-
-
Food and Drug Administration Updated May 13, Accessed July 13, 2016
-
Food and Drug Administration. Generic competition and drug prices. http://www.fda.gov /AboutFDA/CentersOffices /OfficeofMedicalProductsandTobacco/CDER /ucm129385.htm. Updated May 13, 2015. Accessed July 13, 2016.
-
(2015)
Generic Competition and Drug Prices
-
-
-
50
-
-
84873612955
-
-
Government Accountability Office Published January 31, Accessed July 13, 2016
-
Government Accountability Office. Drug pricing: research on savings from generic drug use. http://www.gao.gov/assets/590/588064.pdf. Published January 31, 2012. Accessed July 13, 2016.
-
(2012)
Drug Pricing: Research on Savings from Generic Drug Use
-
-
-
51
-
-
84997095342
-
Reckitt's Suboxone strategy is really about patients or profits?
-
Published October 12, Accessed July 13, 2016
-
Silverman E. Reckitt's Suboxone strategy is really about patients or profits? Forbes. http://www .forbes.com/sites/edsilverman/2012/10/12 /reckitts-suboxone-strategy-is-really-about -patients-or-profits/. Published October 12, 2012. Accessed July 13, 2016.
-
(2012)
Forbes.
-
-
Silverman, E.1
-
52
-
-
84870850733
-
Polymorphs and prodrugs and salts (ohmy!): An empirical analysis of "secondary" pharmaceutical patents
-
Kapczynski A, Park C, Sampat B. Polymorphs and prodrugs and salts (ohmy!): an empirical analysis of "secondary" pharmaceutical patents. PLoS One. 2012;7(12):e49470.
-
(2012)
PLoS One.
, vol.7
, Issue.12
, pp. e49470
-
-
Kapczynski, A.1
Park, C.2
Sampat, B.3
-
56
-
-
33751213872
-
Paying for delay: Pharmaceutical patent settlement as a regulatory design problem
-
Hemphill CS. Paying for delay: pharmaceutical patent settlement as a regulatory design problem. New York Univ Law Rev. 2006;81:1553-1623.
-
(2006)
New York Univ Law Rev.
, vol.81
, pp. 1553-1623
-
-
Hemphill, C.S.1
-
57
-
-
84872682197
-
Economic and technological drivers of generic sterile injectable drug shortages
-
Woodcock J, WosinskaM. Economic and technological drivers of generic sterile injectable drug shortages. Clin Pharmacol Ther. 2013;93(2): 170-176.
-
(2013)
Clin Pharmacol Ther.
, vol.93
, Issue.2
, pp. 170-176
-
-
Woodcock, J.1
Wosinska, M.2
-
58
-
-
84997291256
-
-
(GDUFA). Testimony before the Committee on Health, Education, Labor and Pensions United States Senate. January 28, 2016 Accessed July 15, 2016
-
Woodcock J. Implementation of the Generic Drug User Fee Amendments of 2012 (GDUFA). Testimony before the Committee on Health, Education, Labor and Pensions United States Senate. January 28, 2016. http://www.help.senate .gov/imo/media/doc/Woodcock5.pdf. Accessed July 15, 2016.
-
(2012)
Implementation of the Generic Drug User Fee Amendments of
-
-
Woodcock, J.1
-
59
-
-
84898669844
-
Using a drug-safety tool to prevent competition
-
Sarpatwari A, Avorn J, Kesselheim AS. Using a drug-safety tool to prevent competition. N Engl J Med. 2014;370(16):1476-1478.
-
(2014)
N Engl J Med.
, vol.370
, Issue.16
, pp. 1476-1478
-
-
Sarpatwari, A.1
Avorn, J.2
Kesselheim, A.S.3
-
60
-
-
77952417326
-
-
US Government Publishing Office. Pub. L. No. 111-148, 124 Stat.
-
US Government Publishing Office. Pub. L. No. 111-148, 124 Stat. 119 (2010): Patient Protection and Affordable Care Act.
-
(2010)
Patient Protection and Affordable Care Act
, vol.119
-
-
-
61
-
-
84959479847
-
The case for reforming drug naming: Should brand name trademark protection expire upon generic entry?
-
Sarpatwari A, Kesselheim AS. The case for reforming drug naming: should brand name trademark protection expire upon generic entry? PLoS Med. 2016;13(2):e1001955.
-
(2016)
PLoS Med.
, vol.13
, Issue.2
, pp. e1001955
-
-
Sarpatwari, A.1
Kesselheim, A.S.2
-
62
-
-
77958040408
-
State generic substitution laws can lower drug outlays under Medicaid
-
Shrank WH, Choudhry NK, Agnew-Blais J, et al. State generic substitution laws can lower drug outlays under Medicaid. Health Aff (Millwood). 2010;29(7):1383-1390.
-
(2010)
Health Aff (Millwood).
, vol.29
, Issue.7
, pp. 1383-1390
-
-
Shrank, W.H.1
Choudhry, N.K.2
Agnew-Blais, J.3
-
63
-
-
79952950489
-
The consequences of requesting "dispense as written. "
-
Shrank WH, Liberman JN, Fischer MA, et al. The consequences of requesting "dispense as written. " Am J Med. 2011;124(4):309-317.
-
(2011)
Am J Med.
, vol.124
, Issue.4
, pp. 309-317
-
-
Shrank, W.H.1
Liberman, J.N.2
Ma, F.3
-
64
-
-
84945468446
-
Reductions in use of colchicine after FDA enforcement of market exclusivity in a commercially insured population
-
Kesselheim AS, Franklin JM, Kim SC, Seeger JD, Solomon DH. Reductions in use of colchicine after FDA enforcement of market exclusivity in a commercially insured population. J Gen Intern Med. 2015;30(11):1633-1638.
-
(2015)
J Gen Intern Med.
, vol.30
, Issue.11
, pp. 1633-1638
-
-
Kesselheim, A.S.1
Franklin, J.M.2
Kim, S.C.3
Seeger, J.D.4
Solomon, D.H.5
-
65
-
-
84937485230
-
The impact of the US Food and Drug Administration chlorofluorocarbon ban on out-of-pocket costs and use of albuterol inhalers among individuals with asthma
-
Jena AB, Ho O, Goldman DP, Karaca-Mandic P. The impact of the US Food and Drug Administration chlorofluorocarbon ban on out-of-pocket costs and use of albuterol inhalers among individuals with asthma. JAMA Intern Med. 2015;175(7):1171-1179.
-
(2015)
JAMA Intern Med.
, vol.175
, Issue.7
, pp. 1171-1179
-
-
Jena, A.B.1
Ho, O.2
Goldman, D.P.3
Karaca-Mandic, P.4
-
66
-
-
33846878293
-
Economic return of clinical trials performed under the pediatric exclusivity program
-
Li JS, Eisenstein EL, Grabowski HG, et al. Economic return of clinical trials performed under the pediatric exclusivity program. JAMA. 2007;297 (5):480-488.
-
(2007)
JAMA.
, vol.297
, Issue.5
, pp. 480-488
-
-
Li, J.S.1
Eisenstein, E.L.2
Grabowski, H.G.3
-
67
-
-
84997404204
-
-
Centers for Medicare and Medicaid Services Published July 28, Accessed July 13, 2016
-
Centers for Medicare and Medicaid Services. On its 50th anniversary, more than 55 million Americans covered by Medicare. https://www.cms .gov/Newsroom/MediaReleaseDatabase/Press -releases/2015-Press-releases-items/2015-07-28 .html. Published July 28, 2015. Accessed July 13, 2016.
-
(2015)
On Its 50th Anniversary, More Than 55 Million Americans Covered by Medicare
-
-
-
68
-
-
85024863887
-
-
Kaiser Family Foundation Published June 30, Accessed July 13, 2016
-
Henry J Kaiser Family Foundation. Total monthly Medicaid and CHIP enrollment. http://kff .org/health-reform/state-indicator/total-monthly -medicaid-and-chip-enrollment/. Published June 30, 2016. Accessed July 13, 2016.
-
(2016)
Total Monthly Medicaid and CHIP Enrollment
-
-
Henry, J.1
-
69
-
-
79953172392
-
-
National Center for Health Statistics Published May 24, 2016. Accessed July 13, 2016
-
Cohen RA, Martinez ME, Zammitti EP; National Center for Health Statistics. Early release of selected estimates based on data from the National Health Interview Survey, 2015. http://www.cdc.gov /nchs/nhis/releases/released201605.htm. Published May 24, 2016. Accessed July 13, 2016.
-
(2015)
Early release of selected estimates based on data from the National Health Interview Survey
-
-
Cohen, R.A.1
Martinez, M.E.2
Zammitti, E.P.3
-
70
-
-
84997395058
-
The short answer: Pharmacy-benefit managers
-
Published March 30, Accessed July 13, 2016
-
The short answer: pharmacy-benefit managers.Wall Street Journal. http://blogs.wsj.com /briefly/2015/03/30/pharmacy-benefit-managers -the-short-answer/. Published March 30, 2015. Accessed July 13, 2016.
-
(2015)
Wall Street Journal.
-
-
-
71
-
-
84980418189
-
United States health care reform: Progress to date and next steps
-
doi:10.1001/jama.2016.9797
-
Obama B. United States health care reform: progress to date and next steps. JAMA. doi:10.1001/jama.2016.9797.
-
JAMA.
-
-
Obama, B.1
-
72
-
-
85015899438
-
-
California Health Care Foundation Updated December. Accessed July 13, 2016
-
California Health Care Foundation. US health care spending: who pays? http://www.chcf.org/publications/2015/12/data-viz-hcc-national. Updated December 2015. Accessed July 13, 2016.
-
(2015)
US Health Care Spending: Who Pays?
-
-
-
73
-
-
3342953762
-
A political history of medicare and prescription drug coverage
-
Oliver TR, Lee PR, Lipton HL. A political history of medicare and prescription drug coverage. Milbank Q. 2004;82(2):283-354.
-
(2004)
Milbank Q.
, vol.82
, Issue.2
, pp. 283-354
-
-
Oliver, T.R.1
Lee, P.R.2
Lipton, H.L.3
-
74
-
-
84997070070
-
-
US Government Publishing Office. 42 USC. 1395: health insurance for aged and disabled
-
US Government Publishing Office. 42 USC. 1395: health insurance for aged and disabled.
-
-
-
-
75
-
-
84997421689
-
-
Medicaid.gov. Medicaid drug rebate program Updated June 16, 2016. Accessed July 13, 2016
-
Medicaid.gov. Medicaid drug rebate program. https://www.medicaid.gov/medicaid-chip -program-information/by-topics/benefits /prescription-drugs/medicaid-drug-rebate-program .html. Updated June 16, 2016. Accessed July 13, 2016.
-
-
-
-
76
-
-
84934810686
-
Price-cap regulation, uncertainty and the price evolution of new pharmaceuticals
-
Shajarizadeh A, Hollis A. Price-cap regulation, uncertainty and the price evolution of new pharmaceuticals. Health Econ. 2015;24(8):966-977.
-
(2015)
Health Econ.
, vol.24
, Issue.8
, pp. 966-977
-
-
Shajarizadeh, A.1
Hollis, A.2
-
77
-
-
84904555889
-
Improving health care for veterans- A watershed moment for the VA
-
Chokshi DA. Improving health care for veterans- A watershed moment for the VA. N Engl J Med. 2014;371(4):297-299.
-
(2014)
N Engl J Med.
, vol.371
, Issue.4
, pp. 297-299
-
-
Chokshi, D.A.1
-
78
-
-
22844449333
-
Comparison of drug regimen costs between the Medicare prescription discount program and other purchasing systems
-
Hayes JM, Walczak H, Prochazka A. Comparison of drug regimen costs between the Medicare prescription discount program and other purchasing systems. JAMA. 2005;294(4): 427-428.
-
(2005)
JAMA.
, vol.294
, Issue.4
, pp. 427-428
-
-
Hayes, J.M.1
Walczak, H.2
Prochazka, A.3
-
80
-
-
85050467200
-
-
US Department of Veterans Affairs; Health Economics Resource Center Accessed July 13, 2016
-
US Department of Veterans Affairs; Health Economics Resource Center. Determining the cost of pharmaceuticals for a cost-effectiveness analysis. http://www.herc.research.va.gov/include/page.asp ?id=pharmaceutical-costs. Accessed July 13, 2016.
-
Determining the Cost of Pharmaceuticals for A Cost-effectiveness Analysis
-
-
-
81
-
-
57449089048
-
Controlling prescription drug costs: Regulation and the role of interest groups in Medicare and the Veterans Health Administration
-
Frakt AB, Pizer SD, Hendricks AM. Controlling prescription drug costs: regulation and the role of interest groups in Medicare and the Veterans Health Administration. J Health Polit Policy Law. 2008;33(6):1079-1106.
-
(2008)
J Health Polit Policy Law.
, vol.33
, Issue.6
, pp. 1079-1106
-
-
Frakt, A.B.1
Pizer, S.D.2
Hendricks, A.M.3
-
82
-
-
84937128872
-
-
New York Times. Published December 22, Accessed July 13, 2016
-
Pollack A. AbbVie deal heralds changed landscape for hepatitis drugs. New York Times. http: //www.nytimes.com/2014/12/22/business /pharmacy-deal-heralds-changed-landscape-for -hepatitis-drugs.html. Published December 22, 2014. Accessed July 13, 2016.
-
(2014)
AbbVie Deal Heralds Changed Landscape for Hepatitis Drugs
-
-
Pollack, A.1
-
83
-
-
84997324428
-
Merck kills Medco IPO plan, will spin off unit to holders
-
Updated April 23, Accessed July 13, 2016
-
Martinez B. Merck kills Medco IPO plan, will spin off unit to holders. Wall Street Journal. http: //www.wsj.com/articles/SB105103638029142500. Updated April 23, 2003. Accessed July 13, 2016.
-
(2003)
Wall Street Journal.
-
-
Martinez, B.1
-
84
-
-
84920973827
-
The anatomy of medical research: US and international comparisons
-
Moses H III, Matheson DH, Cairns-Smith S, George BP, Palisch C, Dorsey ER. The anatomy of medical research: US and international comparisons. JAMA. 2015;313(2):174-189.
-
(2015)
JAMA.
, vol.313
, Issue.2
, pp. 174-189
-
-
Moses, H.1
Matheson, D.H.2
Cairns-Smith, S.3
George, B.P.4
Palisch, C.5
Dorsey, E.R.6
-
85
-
-
84959128138
-
Innovation in the pharmaceutical industry: New estimates of R and D costs
-
DiMasi JA, Grabowski HG, Hansen RW. Innovation in the pharmaceutical industry: new estimates of R and D costs. J Health Econ. 2016;47: 20-33.
-
(2016)
J Health Econ.
, vol.47
, pp. 20-33
-
-
DiMasi, J.A.1
Grabowski, H.G.2
Hansen, R.W.3
-
86
-
-
84929359137
-
The 2.6 billion pill-methodologic and policy considerations
-
Avorn J. The 2.6 billion pill-methodologic and policy considerations. N Engl J Med. 2015;372 (20):1877-1879.
-
(2015)
N Engl J Med.
, vol.372
, Issue.20
, pp. 1877-1879
-
-
Avorn, J.1
-
88
-
-
84922704898
-
The roles of academia, rare diseases, and repurposing in the development of the most transformative drugs
-
Kesselheim AS, Tan YT, Avorn J. The roles of academia, rare diseases, and repurposing in the development of the most transformative drugs. Health Aff (Millwood). 2015;34(2):286-293.
-
(2015)
Health Aff (Millwood).
, vol.34
, Issue.2
, pp. 286-293
-
-
Kesselheim, A.S.1
Tan, Y.T.2
Avorn, J.3
-
89
-
-
78049467253
-
The importance of new companies for drug discovery: Origins of a decade of new drugs
-
Kneller R. The importance of new companies for drug discovery: origins of a decade of new drugs. Nat Rev Drug Discov. 2010;9(11):867-882.
-
(2010)
Nat Rev Drug Discov.
, vol.9
, Issue.11
, pp. 867-882
-
-
Kneller, R.1
-
90
-
-
59449100178
-
Market entry and exit by biotech and device companies funded by venture capital
-
Burns LR, Housman MG, Robinson CA. Market entry and exit by biotech and device companies funded by venture capital. Health Aff (Millwood). 2009;28(1):w76-w86.
-
(2009)
Health Aff (Millwood).
, vol.28
, Issue.1
, pp. w76-w86
-
-
Burns, L.R.1
Housman, M.G.2
Robinson, C.A.3
-
91
-
-
84864877975
-
Pharmaceutical research and development: What do we get for all that money?
-
Light DW, Lexchin JR. Pharmaceutical research and development: what do we get for all that money? BMJ. 2012;345:e4348.
-
(2012)
BMJ.
, vol.345
, pp. e4348
-
-
Light, D.W.1
Lexchin, J.R.2
-
92
-
-
77952282664
-
US pharmaceutical innovation in an international context
-
Keyhani S, Wang S, Hebert P, Carpenter D, Anderson G. US pharmaceutical innovation in an international context. Am J Public Health. 2010;100 (6):1075-1080.
-
(2010)
Am J Public Health.
, vol.100
, Issue.6
, pp. 1075-1080
-
-
Keyhani, S.1
Wang, S.2
Hebert, P.3
Carpenter, D.4
Anderson, G.5
-
93
-
-
33645653691
-
Are development times for pharmaceuticals increasing or decreasing?
-
Keyhani S, Diener-West M, Powe N. Are development times for pharmaceuticals increasing or decreasing? Health Aff (Millwood). 2006;25(2): 461-468.
-
(2006)
Health Aff (Millwood).
, vol.25
, Issue.2
, pp. 461-468
-
-
Keyhani, S.1
Diener-West, M.2
Powe, N.3
-
94
-
-
84997167225
-
How Pfizer set the cost of its new drug at 9,850 a month
-
Published December 9, Accessed July 13, 2016
-
Rockoff JD. How Pfizer set the cost of its new drug at 9,850 a month. Wall Street Journal. http: //www.wsj.com/articles/the-art-of-setting-a-drug -price-1449628081. Published December 9, 2015. Accessed July 13, 2016.
-
(2015)
Wall Street Journal
-
-
Rockoff, J.D.1
-
95
-
-
84910122550
-
High-cost generic drugs-implications for patients and policymakers
-
Alpern JD, Stauffer WM, Kesselheim AS. High-cost generic drugs-implications for patients and policymakers. N Engl J Med. 2014;371(20): 1859-1862.
-
(2014)
N Engl J Med.
, vol.371
, Issue.20
, pp. 1859-1862
-
-
Alpern, J.D.1
Stauffer, W.M.2
Kesselheim, A.S.3
-
96
-
-
84997543694
-
-
US House Committee on Oversight and Government Reform Accessed February 5, 2016
-
US House Committee on Oversight and Government Reform. Documents obtained by committee from Turing Pharmaceuticals. http: //democrats.oversight.house.gov/sites/democrats .oversight.house.gov/files/documents/Memo %20on%20Turing%20Documents.pdf. Accessed February 5, 2016.
-
Documents Obtained by Committee from Turing Pharmaceuticals
-
-
-
97
-
-
84997217567
-
The drug that is bankrupting America
-
Published February 16, Accessed July 13, 2016
-
Sachs J. The drug that is bankrupting America. Huffington Post. http://www.huffingtonpost.com /jeffrey-sachs/the-drug-that-is-bankrupt-b-6692340.html. Published February 16, 2015. Accessed July 13, 2016.
-
(2015)
Huffington Post.
-
-
Sachs, J.1
-
98
-
-
84930383566
-
-
New York Times. Published February 3, Accessed July 13, 2016
-
Pollack A. Sales of Sovaldi, new Gilead hepatitis C drug soar to 10.3 billion. New York Times. http: //www.nytimes.com/2015/02/04/business/sales -of-sovaldi-new-gilead-hepatitis-c-drug-soar-to-10 -3-billion.html. Published February 3, 2015. Accessed July 13, 2016.
-
(2015)
Sales of Sovaldi, New Gilead Hepatitis C Drug Soar to 10.3 Billion
-
-
Pollack, A.1
-
99
-
-
84997313728
-
-
United States Senate Committee on Finance Published December. Accessed July 13, 2016
-
United States Senate Committee on Finance. The price of Sovaldi and its impact on the US health care system. http://www.finance.senate.gov/imo /media/doc/1%20The%20Price%20of %20Sovaldi%20and%20Its%20Impact%20on %20the%20US%20Health%20Care%20System %20(Full%20Report).pdf. Published December 2015. Accessed July 13, 2016.
-
The Price of Sovaldi and Its Impact on the US Health Care System
-
-
-
100
-
-
84901008072
-
Nonlinear pricing in drug benefits and medication use: The case of statin compliance in Medicare Part D
-
Jung K, Feldman R, McBean AM. Nonlinear pricing in drug benefits and medication use: the case of statin compliance in Medicare Part D. Health Serv Res. 2014;49(3):910-928
-
(2014)
Health Serv Res
, vol.49
, Issue.3
, pp. 910-928
-
-
Jung, K.1
Feldman, R.2
McBean, A.M.3
-
101
-
-
84884900894
-
Responses to Medicare drug costs among near-poor versus subsidized beneficiaries
-
Fung V, Reed M, Price M, et al. Responses to Medicare drug costs among near-poor versus subsidized beneficiaries. Health Serv Res. 2013;48 (5):1653-1668.
-
(2013)
Health Serv Res
, vol.48
, Issue.5
, pp. 1653-1668
-
-
Fung, V.1
Reed, M.2
Price, M.3
-
102
-
-
84966475689
-
-
Kaiser Family Foundation Published September 22, 2015. Accessed July 13, 2016
-
Henry J Kaiser Family Foundation. 2015 Employer health benefits survey. http://kff.org /report-section/ehbs-2015-summary-of-findings/. Published September 22, 2015. Accessed July 13, 2016.
-
(2015)
Employer Health Benefits Survey
-
-
Henry, J.1
-
103
-
-
84944458606
-
Health benefits in 2015: Stable trends in the employer market
-
Claxton G, RaeM, Panchal N, et al. Health benefits in 2015: stable trends in the employer market. Health Aff (Millwood). 2015;34(10): 1779-1788.
-
(2015)
Health Aff (Millwood)
, vol.34
, Issue.10
, pp. 1779-1788
-
-
Claxton, G.1
Rae, M.2
Panchal, N.3
-
104
-
-
47949122892
-
Tier 4 drugs and the fraying of the social compact
-
Lee TH, Emanuel EJ. Tier 4 drugs and the fraying of the social compact. N Engl J Med. 2008; 359(4):333-335.
-
(2008)
N Engl J Med.
, vol.359
, Issue.4
, pp. 333-335
-
-
Lee, T.H.1
Emanuel, E.J.2
-
105
-
-
33744472168
-
Unintended consequences of caps on Medicare drug benefits
-
Hsu J, Price M, Huang J, et al. Unintended consequences of caps on Medicare drug benefits. N Engl J Med. 2006;354(22):2349-2359.
-
(2006)
N Engl J Med
, vol.354
, Issue.22
, pp. 2349-2359
-
-
Hsu, J.1
Price, M.2
Huang, J.3
-
106
-
-
34347381507
-
Prescription drug cost sharing: Associations with medication and medical utilization and spending and health
-
Goldman DP, Joyce GF, Zheng Y. Prescription drug cost sharing: associations with medication and medical utilization and spending and health. JAMA. 2007;298(1):61-69.
-
(2007)
JAMA
, vol.298
, Issue.1
, pp. 61-69
-
-
Goldman, D.P.1
Joyce, G.F.2
Zheng, Y.3
-
107
-
-
84952886267
-
-
August Published August 20, 2015. Accessed July 13, 2016
-
DiJulio B, Firth J, Brodie M. Kaiser health tracking poll: August 2015. http://kff.org/health -costs/poll-finding/kaiser-health-tracking-poll -august-2015/. Published August 20, 2015. Accessed July 13, 2016.
-
(2015)
Kaiser Health Tracking Poll
-
-
DiJulio, B.1
Firth, J.2
Brodie, M.3
-
108
-
-
84907218121
-
Comparative effectiveness of generic and brand-name statins on patient outcomes: A cohort study
-
Gagne JJ, Choudhry NK, Kesselheim AS, et al. Comparative effectiveness of generic and brand-name statins on patient outcomes: a cohort study. Ann Intern Med. 2014;161(6):400-407.
-
(2014)
Ann Intern Med.
, vol.161
, Issue.6
, pp. 400-407
-
-
Gagne, J.J.1
Choudhry, N.K.2
Kesselheim, A.S.3
-
109
-
-
84997059195
-
-
IMS Institute for Healthcare Informatics Published June 2013. Accessed July 13, 2016.
-
IMS Institute for Healthcare Informatics. Avoidable costs in US healthcare. http://www .imshealth.com/de-AT/thought-leadership/ims -institute/reports/avoidable-costs. Published June 2013. Accessed July 13, 2016.
-
Avoidable Costs in US Healthcare
-
-
-
110
-
-
84907853401
-
Specialty drug coupons lower out-of-pocket costs and may improve adherence at the risk of increasing premiums
-
Starner CI, Alexander GC, Bowen K, Qiu Y, Wickersham PJ, Gleason PP. Specialty drug coupons lower out-of-pocket costs and may improve adherence at the risk of increasing premiums. Health Aff (Millwood). 2014;33(10):1761-1769.
-
(2014)
Health Aff (Millwood)
, vol.33
, Issue.10
, pp. 1761-1769
-
-
Starner, C.I.1
Alexander, G.C.2
Bowen, K.3
Qiu, Y.4
Wickersham, P.J.5
Gleason, P.P.6
-
111
-
-
84884505684
-
Prescription-drug coupons-no such thing as a free lunch
-
Ross JS, Kesselheim AS. Prescription-drug coupons-no such thing as a free lunch. N Engl J Med. 2013;369(13):1188-1189.
-
(2013)
N Engl J Med.
, vol.369
, Issue.13
, pp. 1188-1189
-
-
Ross, J.S.1
Kesselheim, A.S.2
-
113
-
-
84938795806
-
Restrictions for Medicaid reimbursement of sofosbuvir for the treatment of hepatitis C virus infection in the United States
-
Barua S, Greenwald R, Grebely J, Dore GJ, Swan T, Taylor LE. Restrictions for Medicaid reimbursement of sofosbuvir for the treatment of hepatitis C virus infection in the United States. Ann Intern Med. 2015;163(3):215-223.
-
(2015)
Ann Intern Med.
, vol.163
, Issue.3
, pp. 215-223
-
-
Barua, S.1
Greenwald, R.2
Grebely, J.3
Dore, G.J.4
Swan, T.5
Taylor, L.E.6
-
114
-
-
84938809007
-
Limited access to new hepatitis C virus treatment under state Medicaid programs
-
Canary LA, Klevens RM, Holmberg SD. Limited access to new hepatitis C virus treatment under state Medicaid programs. Ann Intern Med. 2015;163 (3):226-228.
-
(2015)
Ann Intern Med.
, vol.163
, Issue.3
, pp. 226-228
-
-
Canary, L.A.1
Klevens, R.M.2
Holmberg, S.D.3
-
115
-
-
84926407692
-
Why are cancer drugs so expensive in the United States, and what are the solutions?
-
Kantarjian H, Rajkumar SV.Why are cancer drugs so expensive in the United States, and what are the solutions? Mayo Clin Proc. 2015;90(4): 500-504.
-
(2015)
Mayo Clin Proc.
, vol.90
, Issue.4
, pp. 500-504
-
-
Kantarjian, H.1
Rajkumar, S.V.2
-
116
-
-
84978086896
-
Stemming the escalating cost of prescription drugs: A position paper of the American College of Physicians
-
Health and Public Policy Committee of the American College of Physicians doi:10.7326/M15-2768
-
Daniel H; Health and Public Policy Committee of the American College of Physicians. Stemming the escalating cost of prescription drugs: a position paper of the American College of Physicians. Ann Intern Med. doi:10.7326/M15-2768.
-
Ann Intern Med.
-
-
Daniel, H.1
-
118
-
-
84997286716
-
-
Mayo v Prometheus, 132 SCt 1289 (2012)
-
Mayo v Prometheus, 132 SCt 1289 (2012).
-
-
-
-
119
-
-
84997458724
-
-
Alice Corp. v CLS Bank International, 134 SCt 2347 (2014)
-
Alice Corp. v CLS Bank International, 134 SCt 2347 (2014).
-
-
-
-
120
-
-
84891518596
-
To patent or not to patent? the case of Novartis' cancer drug Glivec in India
-
Gabble R, Kohler JC. To patent or not to patent? the case of Novartis' cancer drug Glivec in India. Global Health. 2014;10:3.
-
(2014)
Global Health.
, vol.10
, pp. 3
-
-
Gabble, R.1
Kohler, J.C.2
-
121
-
-
84997426175
-
-
FTC v Actavis, 133 S Ct 2223 (2013)
-
FTC v Actavis, 133 S Ct 2223 (2013).
-
-
-
-
122
-
-
84997426178
-
Status of pay-for-delay cases nearly two years after Actavis-'it ain't over 'til it's over.'
-
Published May 19, 2015. Accessed July 13, 2016
-
Tucker RJ. Status of pay-for-delay cases nearly two years after Actavis-'it ain't over 'til it's over.' Mondaq. http://www.mondaq.com/unitedstates/x /398342/Antitrust+Competition/Status+of+ PayforDelay+Cases+Nearly+Two+Years+After+ Actavis+It+aint+over+til+its+over. Published May 19, 2015. Accessed July 13, 2016.
-
Mondaq
-
-
Tucker, R.J.1
-
123
-
-
84997224087
-
-
New York v Actavis, 787 F3d 638 (2d Cir 2015)
-
New York v Actavis, 787 F3d 638 (2d Cir 2015).
-
-
-
-
124
-
-
84997297587
-
-
Office of the Assistant Secretary for Planning and Evaluation, Department of Health and Human Services Published May 6, 2015. Accessed July 13, 2016
-
Office of the Assistant Secretary for Planning and Evaluation, Department of Health and Human Services. Some observations related to the generic drug market. https://aspe.hhs.gov/sites/default /files/pdf/139331/ib-GenericMarket.pdf. Published May 6, 2015. Accessed July 13, 2016.
-
Some Observations Related to the Generic Drug Market
-
-
-
125
-
-
84857743319
-
Diagnosing the decline in pharmaceutical R and D efficiency
-
Scannell JW, Blanckley A, Boldon H, Warrington B. Diagnosing the decline in pharmaceutical R and D efficiency. Nat Rev Drug Discov. 2012;11(3):191-200.
-
(2012)
Nat Rev Drug Discov.
, vol.11
, Issue.3
, pp. 191-200
-
-
Scannell, J.W.1
Blanckley, A.2
Boldon, H.3
Warrington, B.4
-
126
-
-
34547950500
-
A decade of direct-to-consumer advertising of prescription drugs
-
Donohue JM, Cevasco M, Rosenthal MB. A decade of direct-to-consumer advertising of prescription drugs. N Engl J Med. 2007;357(7): 673-681.
-
(2007)
N Engl J Med.
, vol.357
, Issue.7
, pp. 673-681
-
-
Donohue, J.M.1
Cevasco, M.2
Rosenthal, M.B.3
-
127
-
-
84879552887
-
Direct-to-consumer television advertising exposure, diagnosis with high cholesterol, and statin use
-
Niederdeppe J, Byrne S, Avery RJ, Cantor J. Direct-to-consumer television advertising exposure, diagnosis with high cholesterol, and statin use. J Gen Intern Med. 2013;28(7):886-893.
-
(2013)
J Gen Intern Med.
, vol.28
, Issue.7
, pp. 886-893
-
-
Niederdeppe, J.1
Byrne, S.2
Avery, R.J.3
Cantor, J.4
-
128
-
-
0042821318
-
How does direct-to-consumer advertising (DTCA) affect prescribing? a survey in primary care environments with and without legal DTCA
-
Mintzes B, Barer ML, Kravitz RL, et al. How does direct-to-consumer advertising (DTCA) affect prescribing? a survey in primary care environments with and without legal DTCA. CMAJ. 2003;169(5): 405-412.
-
(2003)
CMAJ.
, vol.169
, Issue.5
, pp. 405-412
-
-
Mintzes, B.1
Barer, M.L.2
Kravitz, R.L.3
-
129
-
-
84940838886
-
Forbidden and permitted statements about medications-loosening the rules
-
Avorn J, Sarpatwari A, Kesselheim AS. Forbidden and permitted statements about medications'loosening the rules. N Engl J Med. 2015;373(10):967-973.
-
(2015)
N Engl J Med.
, vol.373
, Issue.10
, pp. 967-973
-
-
Avorn, J.1
Sarpatwari, A.2
Kesselheim, A.S.3
-
130
-
-
84948158761
-
Options to promote competitive generics markets in the United States
-
Wiske CP, Ogbechie OA, Schulman KA. Options to promote competitive generics markets in the United States. JAMA. 2015;314(20):2129-2130.
-
(2015)
JAMA
, vol.314
, Issue.20
, pp. 2129-2130
-
-
Wiske, C.P.1
Ogbechie, O.A.2
Schulman, K.A.3
-
131
-
-
84997058566
-
-
US Senate 14 Jun Accessed July 13, 2016
-
US Senate. CREATES Act of 2016 (S 3056). 14 Jun 2016. https://www.congress.gov/bill/114th -congress/senate-bill/3056/text. Accessed July 13, 2016.
-
(2016)
CREATES Act of 2016 (S 3056)
-
-
-
132
-
-
84957793312
-
Role of the FDA in affordability of off-patent pharmaceuticals
-
Greene JA, Anderson G, Sharfstein JM. Role of the FDA in affordability of off-patent pharmaceuticals. JAMA. 2016;315(5):461-462.
-
(2016)
JAMA.
, vol.315
, Issue.5
, pp. 461-462
-
-
Greene, J.A.1
Anderson, G.2
Sharfstein, J.M.3
-
133
-
-
84980383599
-
Medicare Part D: Patients bear the cost of 'me too' brand-name drugs
-
Gastala NM, Wingrove P, Gaglioti A, Petterson S, Bazemore A. Medicare Part D: patients bear the cost of 'me too' brand-name drugs. Health Aff (Millwood). 2016;35(7):1237-1240.
-
(2016)
Health Aff (Millwood)
, vol.35
, Issue.7
, pp. 1237-1240
-
-
Gastala, N.M.1
Wingrove, P.2
Gaglioti, A.3
Petterson, S.4
Bazemore, A.5
-
134
-
-
84885403899
-
Biosimilars and the European experience: Implications for the United States
-
Megerlin F, Lopert R, Taymor K, Trouvin JH. Biosimilars and the European experience: implications for the United States. Health Aff (Millwood). 2013;32(10):1803-1810.
-
(2013)
Health Aff (Millwood)
, vol.32
, Issue.10
, pp. 1803-1810
-
-
Megerlin, F.1
Lopert, R.2
Taymor, K.3
Trouvin, J.H.4
-
135
-
-
84885403899
-
Biosimilars and the European experience: Implications for the United States
-
Hennessy S, Leonard CE, Platt R. Assessing the safety and comparative effectiveness of follow-on biologics (biosimilars) in the United States. Clin Pharmacol Ther. 2010;87(2):157-159.
-
(2013)
Health Aff (Millwood)
, vol.32
, Issue.10
, pp. 1803-1810
-
-
Megerlin, F.1
Lopert, R.2
Taymor, K.3
Trouvin, J.H.4
-
136
-
-
84997058596
-
Novartis launches first US 'biosimilar' drug at 15 percent discount
-
Published September 3, 2015. Accessed July 13, 2016
-
Hirschler B, Shields M. Novartis launches first US 'biosimilar' drug at 15 percent discount. Reuters. http://www.reuters.com/article/us-novartis-drug -idUSKCN0R30C220150903. Published September 3, 2015. Accessed July 13, 2016.
-
Reuters
-
-
Hirschler, B.1
Shields, M.2
-
137
-
-
0008348082
-
-
European Medicines Agency Accessed July 31, 2016
-
European Medicines Agency. European public assessment reports. http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/epar-search.jsp&mid=WC0b01ac058001d125. Accessed July 31, 2016.
-
European Public Assessment Reports
-
-
-
138
-
-
84955307891
-
-
IMS Institute for Healthcare Informatics Published October 2014. Accessed July 13, 2016
-
IMS Institute for Healthcare Informatics. Assessing biosimilar uptake and competition in European markets. http://www.imshealth.com/files /web/IMSH%20Institute/Healthcare%20Briefs/Assessing-biosimilar-uptake-and-competition-in -European-markets.pdf. Published October 2014. Accessed July 13, 2016.
-
Assessing Biosimilar Uptake and Competition in European Markets
-
-
-
139
-
-
70349513438
-
-
Commonwealth Fund Published February 2008. Accessed July 13, 2016
-
Anell A. The Swedish health care system. Commonwealth Fund. http://www .commonwealthfund.org/~/media/files/resources /2008/health-care-system-profiles/sweden -country-profile-2008-pdf.pdf. Published February 2008. Accessed July 13, 2016.
-
The Swedish Health Care System
-
-
Anell, A.1
-
140
-
-
84997062953
-
-
Center for Responsive Politics Accessed July 13, 2016
-
Center for Responsive Politics. Lobbying: top industries. https://www.opensecrets.org/lobby/top.php&showYear=a&indexType=i. Accessed July 13, 2016.
-
Lobbying: Top Industries
-
-
-
141
-
-
70349197850
-
How Medicare could get better prices on prescription drugs
-
Outterson K, Kesselheim AS. How Medicare could get better prices on prescription drugs. Health Aff (Millwood). 2009;28(5):w832-w841.
-
(2009)
Health Aff (Millwood)
, vol.28
, Issue.5
, pp. w832-w841
-
-
Outterson, K.1
Kesselheim, A.S.2
-
142
-
-
84959419676
-
Pharmaceutical policy reform-balancing affordability with incentives for innovation
-
Conti RM, Rosenthal MB. Pharmaceutical policy reform-balancing affordability with incentives for innovation. N Engl J Med. 2016;374 (8):703-706.
-
(2016)
N Engl J Med.
, vol.374
, Issue.8
, pp. 703-706
-
-
Conti, R.M.1
Rosenthal, M.B.2
-
143
-
-
84908150068
-
Indication-specific pricing for cancer drugs
-
Bach PB. Indication-specific pricing for cancer drugs. JAMA. 2014;312(16):1629-1630.
-
(2014)
JAMA
, vol.312
, Issue.16
, pp. 1629-1630
-
-
Bach, P.B.1
-
144
-
-
84978935158
-
Implications of proposed Medicare reforms to counteract high drug prices
-
Mailankody S, Prasad V. Implications of proposed Medicare reforms to counteract high drug prices. JAMA. 2016;316(3):271-272.
-
(2016)
JAMA
, vol.316
, Issue.3
, pp. 271-272
-
-
Mailankody, S.1
Prasad, V.2
-
145
-
-
84977521201
-
Reference pricing with endogenous generic entry
-
Brekke KR, Canta C, Straume OR. Reference pricing with endogenous generic entry. J Health Econ. 2016;(16):30021-30022.
-
(2016)
J Health Econ.
, vol.16
, pp. 30021-30022
-
-
Brekke, K.R.1
Canta, C.2
Straume, O.R.3
-
146
-
-
79953731978
-
Reimbursement and value-based pricing: Stratified cost-effectiveness analysis may not be the last word
-
Hawkins N, Scott DA. Reimbursement and value-based pricing: stratified cost-effectiveness analysis may not be the last word. Health Econ. 2011;20(6):688-698.
-
(2011)
Health Econ.
, vol.20
, Issue.6
, pp. 688-698
-
-
Hawkins, N.1
Scott, D.A.2
-
147
-
-
61349178993
-
Health technology assessment in evidence-based health care reimbursement decisions around the world: An overview
-
O'Donnell JC, Pham SV, Pashos CL, et al. Health technology assessment in evidence-based health care reimbursement decisions around the world: an overview. Value Health. 2009;12(suppl 2): S1-S5.
-
(2009)
Value Health.
, vol.12
, pp. S1-S5
-
-
O'Donnell, J.C.1
Pham, S.V.2
Pashos, C.L.3
-
148
-
-
84952907922
-
Measuring the value of prescription drugs
-
Neumann PJ, Cohen JT. Measuring the value of prescription drugs. N Engl J Med. 2015;373(27): 2595-2597.
-
(2015)
N Engl J Med.
, vol.373
, Issue.27
, pp. 2595-2597
-
-
Neumann, P.J.1
Cohen, J.T.2
-
149
-
-
84859864850
-
The Patient-Centered Outcomes Research Institute (PCORI) national priorities for research and initial research agenda
-
Selby JV, Beal AC, Frank L. The Patient-Centered Outcomes Research Institute (PCORI) national priorities for research and initial research agenda. JAMA. 2012;307(15):1583-1584.
-
(2012)
JAMA
, vol.307
, Issue.15
, pp. 1583-1584
-
-
Selby, J.V.1
Beal, A.C.2
Frank, L.3
-
150
-
-
84894297357
-
The politics of comparative effectiveness research: Lessons from recent history
-
Sorenson C, Gusmano MK, Oliver A. The politics of comparative effectiveness research: lessons from recent history. J Health Polit Policy Law. 2014;39(1):139-170.
-
(2014)
J Health Polit Policy Law
, vol.39
, Issue.1
, pp. 139-170
-
-
Sorenson, C.1
Gusmano, M.K.2
Oliver, A.3
-
151
-
-
84997385140
-
-
Center for Public Integrity Published August 4, 2015. Accessed July 13, 2016
-
Schulte F. Obamacare research institute plans to spend 3.5 billion, but critics question its worth. Center for Public Integrity. https://www .publicintegrity.org/2015/08/04/17762 /obamacare-research-institute-plans-spend-35 -billion-critics-question-its-worth. Published August 4, 2015. Accessed July 13, 2016.
-
Obamacare Research Institute Plans to Spend 3.5 Billion, but Critics Question Its Worth
-
-
Schulte, F.1
-
152
-
-
84950141258
-
Payer and policy maker steps to support value-based pricing for drugs
-
Bach PB, Pearson SD. Payer and policy maker steps to support value-based pricing for drugs. JAMA. 2015;314(23):2503-2504.
-
(2015)
JAMA
, vol.314
, Issue.23
, pp. 2503-2504
-
-
Bach, P.B.1
Pearson, S.D.2
-
153
-
-
84997396869
-
-
Medical Letter. About us Accessed July 13, 2016
-
Medical Letter. About us. http://secure .medicalletter.org/aboutus. Accessed July 13, 2016.
-
-
-
-
154
-
-
84997478375
-
-
Independent Drug Information Service Accessed July 13, 2016
-
Independent Drug Information Service. Alosa Foundation. http://www.alosafoundation.org /independent-drug-information-service/. Accessed July 13, 2016.
-
Alosa Foundation
-
-
-
155
-
-
33746926720
-
Emerging lessons from the Drug Effectiveness Review Project
-
Neumann PJ. Emerging lessons from the Drug Effectiveness Review Project. Health Aff (Millwood). 2006;25(4):W262-W271.
-
(2006)
Health Aff (Millwood)
, vol.25
, Issue.4
, pp. W262-W271
-
-
Neumann, P.J.1
-
156
-
-
33746888229
-
Bringing the DERP to consumers: Consumer Reports Best Buy Drugs
-
Findlay SD. Bringing the DERP to consumers: Consumer Reports Best Buy Drugs. Health Aff (Millwood). 2006;25(4):W283-W286.
-
(2006)
Health Aff (Millwood)
, vol.25
, Issue.4
, pp. W283-W286
-
-
Findlay, S.D.1
-
157
-
-
84922419758
-
Pricing in the market for anticancer drugs: NBER working paper 20867
-
Howard DH, Bach PB, Berndt ER, Conti RM. Pricing in the market for anticancer drugs: NBER working paper 20867. J Econ Perspectives. 2015;29 (1):139-162.
-
(2015)
J Econ Perspectives
, vol.29
, Issue.1
, pp. 139-162
-
-
Howard, D.H.1
Bach, P.B.2
Berndt, E.R.3
Conti, R.M.4
-
158
-
-
84982893727
-
Five years of cancer drug approvals
-
Mailankody S, Prasad V. Five years of cancer drug approvals. JAMA Oncol. 2015;1(4): 539-540.
-
(2015)
JAMA Oncol.
, vol.1
, Issue.4
, pp. 539-540
-
-
Mailankody, S.1
Prasad, V.2
-
159
-
-
84973503043
-
Perspectives on cost and value in cancer care
-
Saltz LB. Perspectives on cost and value in cancer care. JAMA Oncol. 2016;2(1):19-21.
-
(2016)
JAMA Oncol.
, vol.2
, Issue.1
, pp. 19-21
-
-
Saltz, L.B.1
-
160
-
-
84939251874
-
American Society of Clinical Oncology statement: A conceptual framework to assess the value of cancer treatment options
-
American Society of Clinical Oncology
-
Schnipper LE, Davidson NE,Wollins DS, et al; American Society of Clinical Oncology. American Society of Clinical Oncology statement: a conceptual framework to assess the value of cancer treatment options. J Clin Oncol. 2015;33(23): 2563-2577.
-
(2015)
J Clin Oncol.
, vol.33
, Issue.23
, pp. 2563-2577
-
-
Schnipper, L.E.1
Davidson, N.E.2
Wollins, D.S.3
-
161
-
-
84969195206
-
Utility of cancer value frameworks for patients, payers, and physicians
-
Chandra A, Shafrin J, Dhawan R. Utility of cancer value frameworks for patients, payers, and physicians. JAMA. 2016;315(19):2069-2070.
-
(2016)
JAMA
, vol.315
, Issue.19
, pp. 2069-2070
-
-
Chandra, A.1
Shafrin, J.2
Dhawan, R.3
-
162
-
-
84997148604
-
-
Forbes.com Published May 18, 2016. Accessed August 4, 2016
-
LaMattina J. 'Pay for performance' drug plans could impact biopharma's R and D priorities. Forbes.com. http://www.forbes.com/sites /johnlamattina/2016/05/18/pay-for-performance -drug-plans-could-impact-biopharmas-rd-priorities /#7d98d0513c68. Published May 18, 2016. Accessed August 4, 2016.
-
'Pay for Performance' Drug Plans Could Impact Biopharma's R and D Priorities
-
-
LaMattina, J.1
-
163
-
-
84973121382
-
Sustainable financing of innovative therapies: A review of approaches
-
doi:10.1007/s40273 -016-0416-x
-
Hollis A. Sustainable financing of innovative therapies: a review of approaches. Pharmacoeconomics. 2016. doi:10.1007/s40273 -016-0416-x.
-
(2016)
Pharmacoeconomics
-
-
Hollis, A.1
-
164
-
-
84997478544
-
-
US Government Publishing Office. 28 USC 1498: judiciary and judicial procedure
-
US Government Publishing Office. 28 USC 1498: judiciary and judicial procedure.
-
-
-
-
165
-
-
84969263651
-
Government patent use': A legal approach to reducing drug spending
-
Kapczynski A, Kesselheim AS. 'Government patent use': a legal approach to reducing drug spending. Health Aff (Millwood). 2016;35(5): 791-797.
-
(2016)
Health Aff (Millwood)
, vol.35
, Issue.5
, pp. 791-797
-
-
Kapczynski, A.1
Kesselheim, A.S.2
-
166
-
-
0011416641
-
Why don't we enforce existing drug price controls? the unrecognized and unenforced reasonable pricing requirements imposed upon patents deriving in whole or in part from federally funded research
-
Arno PS, Davis MH. Why don't we enforce existing drug price controls? the unrecognized and unenforced reasonable pricing requirements imposed upon patents deriving in whole or in part from federally funded research. Tulane Law Rev. 2001;75:631-693.
-
(2001)
Tulane Law Rev.
, vol.75
, pp. 631-693
-
-
Arno, P.S.1
Davis, M.H.2
-
168
-
-
84962086899
-
Do March-in rights ensure access to medical products arising from federally funded research?
-
Treasure CL, Avorn J, Kesselheim AS. Do march-in rights ensure access to medical products arising from federally funded research? Milbank Q. 2015;93(4):761-787.
-
(2015)
Milbank Q.
, vol.93
, Issue.4
, pp. 761-787
-
-
Treasure, C.L.1
Avorn, J.2
Kesselheim, A.S.3
-
169
-
-
84885822183
-
Full disclosure-out-of-pocket costs as side effects
-
Ubel PA, Abernethy AP, Zafar SY. Full disclosure'out-of-pocket costs as side effects. N Engl J Med. 2013;369(16):1484-1486.
-
(2013)
N Engl J Med.
, vol.369
, Issue.16
, pp. 1484-1486
-
-
Ubel, P.A.1
Abernethy, A.P.2
Zafar, S.Y.3
-
170
-
-
84871983524
-
Academic detailing can play a key role in assessing and implementing comparative effectiveness research findings
-
Fischer MA, Avorn J. Academic detailing can play a key role in assessing and implementing comparative effectiveness research findings. Health Aff (Millwood). 2012;31(10):2206-2212.
-
(2012)
Health Aff (Millwood)
, vol.31
, Issue.10
, pp. 2206-2212
-
-
Ma, F.1
Avorn, J.2
-
171
-
-
38349046272
-
Educational outreach visits: Effects on professional practice and health care outcomes
-
O'Brien MA, Rogers S, Jamtvedt G, et al. Educational outreach visits: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2007;4(4):CD000409.
-
(2007)
Cochrane Database Syst Rev.
, vol.4
, Issue.4
, pp. CD000409
-
-
Ma, O.1
Rogers, S.2
Jamtvedt, G.3
-
172
-
-
84997164387
-
-
Where is academic detailing used? Accessed July 13, 2016
-
Where is academic detailing used? http://www .alosafoundation.org/academic-detailing/where -academic-detailing-used/. Accessed July 13, 2016.
-
-
-
-
173
-
-
84862491905
-
Changing physician incentives for cancer care to reward better patient outcomes instead of use of more costly drugs
-
Newcomer LN. Changing physician incentives for cancer care to reward better patient outcomes instead of use of more costly drugs. Health Aff (Millwood). 2012;31(4):780-785.
-
(2012)
Health Aff (Millwood)
, vol.31
, Issue.4
, pp. 780-785
-
-
Newcomer, L.N.1
-
174
-
-
84884977696
-
Value and payment for oncology in the United States
-
Robinson JC. Value and payment for oncology in the United States. Ann Pharm Fr. 2013;71(5): 285-290.
-
(2013)
Ann Pharm Fr.
, vol.71
, Issue.5
, pp. 285-290
-
-
Robinson, J.C.1
-
175
-
-
84921887789
-
Using drugs to discriminate-adverse selection in the insurance marketplace
-
Jacobs DB, Sommers BD. Using drugs to discriminate-adverse selection in the insurance marketplace. N Engl J Med. 2015;372(5): 399-402.
-
(2015)
N Engl J Med.
, vol.372
, Issue.5
, pp. 399-402
-
-
Jacobs, D.B.1
Sommers, B.D.2
-
176
-
-
79952278274
-
At Pitney Bowes, value-based insurance design cut copayments and increased drug adherence
-
Choudhry NK, Fischer MA, Avorn J, et al. At Pitney Bowes, value-based insurance design cut copayments and increased drug adherence. Health Aff (Millwood). 2010;29(11):1995-2001.
-
(2010)
Health Aff (Millwood)
, vol.29
, Issue.11
, pp. 1995-2001
-
-
Choudhry, N.K.1
Ma, F.2
Avorn, J.3
-
177
-
-
82555196119
-
Post-Myocardial Infarction Free Rx Event and Economic Evaluation (MI FREEE) Trial. Full coverage for preventive medications aftermyocardial infarction
-
Choudhry NK, Avorn J, Glynn RJ, et al; Post-Myocardial Infarction Free Rx Event and Economic Evaluation (MI FREEE) Trial. Full coverage for preventive medications aftermyocardial infarction. N Engl J Med. 2011;365(22):2088-2097.
-
(2011)
N Engl J Med.
, vol.365
, Issue.22
, pp. 2088-2097
-
-
Choudhry, N.K.1
Avorn, J.2
Glynn, R.J.3
|