AKT1 as the PageRank hub gene is associated with melanoma and its functional annotation is highly related to the estrogen signaling pathway that may regulate the growth of melanoma

Oncology Reports

Volumn 36, Issue 4, 2016, Pages 2087-2093

  Zhao, Jingjing ^a   Zeng, Xue ^b   Song, Ping ^b   Wu, Xiaohong ^b   Shi, Hongbo ^a  

^a School of Information Science and Engineering   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

AKT1; Differentially expressed genes; Estrogen signaling pathway; Melanoma; PageRank score

Indexed keywords

ESTROGEN; RAP1 PROTEIN; AKT1 PROTEIN, HUMAN; ESTROGEN RECEPTOR; PROTEIN KINASE B; TELOMERE BINDING PROTEIN; TERF2IP PROTEIN, HUMAN; TRANSCRIPTOME;

AKT1 GENE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ASSOCIATION; HUMAN; MELANOMA; NEGATIVE FEEDBACK; PRIORITY JOURNAL; RAP1 GENE; SIGNAL TRANSDUCTION; TUMOR INVASION; DNA MICROARRAY; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PATHOLOGY; SKIN TUMOR;

ESTROGENS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; MELANOMA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TELOMERE-BINDING PROTEINS; TRANSCRIPTOME;

EID: 84985032165     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2016.5048     Document Type: Article

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