Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 311, Issue 2, 2016, Pages R299-R306

  Sakuta, Hiraki ^a,b   Nishihara, Eri ^a   Hiyama, Takeshi Y ^a,b   Lin, Chia Hao ^a   Noda, Masaharu ^a,b  

^a NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

Epoxyeicosatrienoic acid; Nax; TRPV1; TRPV4; Water intake

Indexed keywords

EPOXYICOSATRIENOIC ACID; HYPERTONIC SOLUTION; MICONAZOLE; SODIUM; SODIUM CHLORIDE; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 4; HYDROXYICOSATETRAENOIC ACID; SCN7A PROTEIN, MOUSE; TRPV4 PROTEIN, MOUSE; VANILLOID RECEPTOR; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CELL STIMULATION; CEREBROSPINAL FLUID; CIRCUMVENTRICULAR ORGAN; CONTROLLED STUDY; FLUID INTAKE; GENOTYPE; GLIA CELL; MALE; MOUSE; NERVE CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; BRAIN; CHANNEL GATING; DRINKING; FOOD INTAKE; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; APPETITE REGULATION; BRAIN; CEREBROSPINAL FLUID; DRINKING; HYDROXYEICOSATETRAENOIC ACIDS; ION CHANNEL GATING; MALE; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SODIUM; TRPV CATION CHANNELS; VOLTAGE-GATED SODIUM CHANNELS;

EID: 84984660695     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00352.2015     Document Type: Article

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