메뉴 건너뛰기




Volumn 310, Issue 11, 2016, Pages F1168-F1174

FGF23 from bench to bedside

Author keywords

Bone; Heart; Kidney

Indexed keywords

FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR RECEPTOR; KLOTHO PROTEIN; PHOSPHATE; VITAMIN D; BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR;

EID: 84984657046     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00606.2015     Document Type: Article
Times cited : (59)

References (128)
  • 1
    • 0030738679 scopus 로고    scopus 로고
    • Cardiac disease in chronic uremia: Pathophysiology
    • Amann K, Ritz E. Cardiac disease in chronic uremia: pathophysiology. Adv Ren Replace Ther 4: 212–224, 1997.
    • (1997) Adv Ren Replace Ther , vol.4 , pp. 212-224
    • Amann, K.1    Ritz, E.2
  • 2
    • 0028417569 scopus 로고
    • A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia
    • Amann K, Ritz E, Wiest G, Klaus G, Mall G. A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia. JAmSoc Nephrol 4: 1814–1819, 1994.
    • (1994) Jamsoc Nephrol , vol.4 , pp. 1814-1819
    • Amann, K.1    Ritz, E.2    Wiest, G.3    Klaus, G.4    Mall, G.5
  • 3
    • 0028895219 scopus 로고
    • Blood-pressure-independent wall thickening of intramyocardial arterioles in experimental uraemia: Evidence for a permissive action of PTH
    • Amann K, Tornig J, Flechtenmacher C, Nabokov A, Mall G, Ritz E. Blood-pressure-independent wall thickening of intramyocardial arterioles in experimental uraemia: evidence for a permissive action of PTH. Nephrol Dial Transplant 10: 2043–2048, 1995.
    • (1995) Nephrol Dial Transplant , vol.10 , pp. 2043-2048
    • Amann, K.1    Tornig, J.2    Flechtenmacher, C.3    Nabokov, A.4    Mall, G.5    Ritz, E.6
  • 11
    • 13544270218 scopus 로고    scopus 로고
    • An FGF23 missense mutation causes familial tumoral calcinosis with hyperphos-phatemia
    • Benet-Pages A, Orlik P, Strom TM, Lorenz-Depiereux B. An FGF23 missense mutation causes familial tumoral calcinosis with hyperphos-phatemia. Hum Mol Genet 14: 385–390, 2005.
    • (2005) Hum Mol Genet , vol.14 , pp. 385-390
    • Benet-Pages, A.1    Orlik, P.2    Strom, T.M.3    Lorenz-Depiereux, B.4
  • 12
    • 0025675680 scopus 로고
    • Remodeling of the rat right and left ventricles in experimental hypertension
    • Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res 67: 1355–1364, 1990.
    • (1990) Circ Res , vol.67 , pp. 1355-1364
    • Brilla, C.G.1    Pick, R.2    Tan, L.B.3    Janicki, J.S.4    Weber, K.T.5
  • 13
    • 0029554389 scopus 로고
    • The renin-angiotensin-aldosterone system and myocardial collagen matrix remodelling in congestive heart failure
    • Brilla CG, Rupp H, Funck R, Maisch B. The renin-angiotensin-aldosterone system and myocardial collagen matrix remodelling in congestive heart failure. Eur Heart J 16, Suppl O: 107–109, 1995.
    • (1995) Eur Heart J , vol.16 , pp. 107-109
    • Brilla, C.G.1    Rupp, H.2    Funck, R.3    Maisch, B.4
  • 14
    • 0030725787 scopus 로고    scopus 로고
    • Inhibitors induces a regression of left ventricular hypertrophy of dialyzed uremic patients independently from hypotensive effects
    • Cannella G, Paoletti E, Delfino R, Peloso G, Rolla D, Molinari S. Prolonged therapy with ACE inhibitors induces a regression of left ventricular hypertrophy of dialyzed uremic patients independently from hypotensive effects. Am J Kidney Dis 30: 659–664, 1997.
    • (1997) Am J Kidney Dis , vol.30 , pp. 659-664
    • Cannella, G.1    Paoletti, E.2    Delfino, R.3    Peloso, G.4    Rolla, D.5    Molinari, S.6    Prolonged Therapy With, A.7
  • 15
    • 47749148805 scopus 로고    scopus 로고
    • Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
    • Cha SK, Ortega B, Kurosu H, Rosenblatt KP, Kuro O, Huang CL. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci USA 105: 9805–9810, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9805-9810
    • Cha, S.K.1    Ortega, B.2    Kurosu, H.3    Rosenblatt, K.P.4    Kuro, O.5    Huang, C.L.6
  • 17
    • 84897387163 scopus 로고    scopus 로고
    • Paricalcitol- or cinacalcet-centred therapy affects markers of bone mineral disease in patients with secondary hyperparathyroidism receiving haemodialysis: Results of the IMPACT-SHPT study
    • Cozzolino M, Ketteler M, Martin KJ, Sharma A, Goldsmith D, Khan S. Paricalcitol- or cinacalcet-centred therapy affects markers of bone mineral disease in patients with secondary hyperparathyroidism receiving haemodialysis: results of the IMPACT-SHPT study. Nephrol Dial Transplant 29: 899–905, 2014.
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 899-905
    • Cozzolino, M.1    Ketteler, M.2    Martin, K.J.3    Sharma, A.4    Goldsmith, D.5    Khan, S.6
  • 19
    • 84866127175 scopus 로고    scopus 로고
    • A Comparative Transcriptome Analysis Identifying FGF23 Regulated Genes in the Kidney of a Mouse CKD Model
    • Dai B, David V, Martin A, Huang J, Li H, Jiao Y, Gu W, Quarles LD. A Comparative Transcriptome Analysis Identifying FGF23 Regulated Genes in the Kidney of a Mouse CKD Model. PLoS One 7: e44161, 2012.
    • (2012) Plos One , vol.7
    • Dai, B.1    David, V.2    Martin, A.3    Huang, J.4    Li, H.5    Jiao, Y.6    Gu, W.7    Quarles, L.D.8
  • 21
    • 84958962587 scopus 로고    scopus 로고
    • Enhanced FGF23 production in mice expressing PI3K-insensitive GSK3 is normalized by beta-blocker treatment
    • Fajol A, Chen H, Umbach AT, Quarles LD, Lang F, Foller M. Enhanced FGF23 production in mice expressing PI3K-insensitive GSK3 is normalized by beta-blocker treatment. FASEB J 30: 994–1001, 2016.
    • (2016) FASEB J , vol.30 , pp. 994-1001
    • Fajol, A.1    Chen, H.2    Umbach, A.T.3    Quarles, L.D.4    Lang, F.5    Foller, M.6
  • 25
    • 0029054217 scopus 로고
    • The prognostic importance of left ventricular geometry in uremic cardiomyopathy
    • Foley RN. The prognostic importance of left ventricular geometry in uremic cardiomyopathy. Am J Soc Nephrol 5: 2024–2031, 1995.
    • (1995) Am J Soc Nephrol , vol.5 , pp. 2024-2031
    • Foley, R.N.1
  • 27
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296–1305, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 30
    • 84919875524 scopus 로고    scopus 로고
    • Dietary phosphorus restriction by a standard low-protein diet decreased serum fibroblast growth factor 23 levels in patients with early and advanced stage chronic kidney disease
    • Goto S, Nakai K, Kono K, Yonekura Y, Ito J, Fujii H, Nishi S. Dietary phosphorus restriction by a standard low-protein diet decreased serum fibroblast growth factor 23 levels in patients with early and advanced stage chronic kidney disease. Clin Exp Nephrol 18: 925–931, 2014.
    • (2014) Clin Exp Nephrol , vol.18 , pp. 925-931
    • Goto, S.1    Nakai, K.2    Kono, K.3    Yonekura, Y.4    Ito, J.5    Fujii, H.6    Nishi, S.7
  • 32
    • 0027949369 scopus 로고
    • Determinants of left ventricular hypertrophy and systolic dysfunction in chronic renal failure
    • Greaves SC, Gamble GD, Collins JF, Whalley GA, Sharpe DN. Determinants of left ventricular hypertrophy and systolic dysfunction in chronic renal failure. Am J Kidney Dis 24: 768–776, 1994.
    • (1994) Am J Kidney Dis , vol.24 , pp. 768-776
    • Greaves, S.C.1    Gamble, G.D.2    Collins, J.F.3    Whalley, G.A.4    Sharpe, D.N.5
  • 38
    • 84984597957 scopus 로고    scopus 로고
    • Counter-regulatory paracrine actions of FGF-23 and 1,25(OH)2D in macrophages
    • Han X, Lin L, Yang J, King G, Xiao Z, Quarles LD. Counter-regulatory paracrine actions of FGF-23 and 1,25(OH)2D in macrophages. FEBS Lett In Press.
    • FEBS Lett
    • Han, X.1    Lin, L.2    Yang, J.3    King, G.4    Xiao, Z.5    Quarles, L.D.6
  • 39
    • 0028313403 scopus 로고
    • Risk factors for the development of left ventricular hypertrophy in a prospectively followed cohort of dialysis patients
    • Harnett JD, Kent GM, Barre PE, Taylor R, Parfrey PS. Risk factors for the development of left ventricular hypertrophy in a prospectively followed cohort of dialysis patients. J Am Soc Nephrol 4: 1486–1490, 1994.
    • (1994) J am Soc Nephrol , vol.4 , pp. 1486-1490
    • Harnett, J.D.1    Kent, G.M.2    Barre, P.E.3    Taylor, R.4    Parfrey, P.S.5
  • 47
    • 77955814651 scopus 로고    scopus 로고
    • Hormone-like (Endocrine) Fgfs: Their evolutionary history and roles in development, metabolism, and disease
    • Itoh N. Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease. Cell Tissue Res 342: 1–11, 2010.
    • (2010) Cell Tissue Res , vol.342 , pp. 1-11
    • Itoh, N.1
  • 48
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 20: 563–569, 2004.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 49
    • 38149134409 scopus 로고    scopus 로고
    • Functional evolutionary history of the mouse Fgf gene family
    • Itoh N, Ornitz DM. Functional evolutionary history of the mouse Fgf gene family. Dev Dyn 237: 18–27, 2008.
    • (2008) Dev Dyn , vol.237 , pp. 18-27
    • Itoh, N.1    Ornitz, D.M.2
  • 50
  • 51
    • 0035720091 scopus 로고    scopus 로고
    • A malnu-trition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients
    • Kalantar-Zadeh K, Kopple JD, Block G, Humphreys MH. A malnu-trition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. Am J Kidney Dis 38: 1251–1263, 2001.
    • (2001) Am J Kidney Dis , vol.38 , pp. 1251-1263
    • Kalantar-Zadeh, K.1    Kopple, J.D.2    Block, G.3    Humphreys, M.H.4
  • 52
    • 1642413198 scopus 로고    scopus 로고
    • Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization
    • Keith DS, Nichols GA, Gullion CM, Brown JB, Smith DH. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large managed care organization. Arch Intern Med 164: 659–663, 2004.
    • (2004) Arch Intern Med , vol.164 , pp. 659-663
    • Keith, D.S.1    Nichols, G.A.2    Gullion, C.M.3    Brown, J.B.4    Smith, D.H.5
  • 56
    • 81255194004 scopus 로고    scopus 로고
    • Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism
    • Koizumi M, Komaba H, Nakanishi S, Fujimori A, Fukagawa M. Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism. Nephrol Dial Transplant 27: 784– 790, 2012.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 784-790
    • Koizumi, M.1    Komaba, H.2    Nakanishi, S.3    Fujimori, A.4    Fukagawa, M.5
  • 57
    • 84884522131 scopus 로고    scopus 로고
    • Fibroblast growth factor-23: What we know, what we don’t know, and what we need to know
    • Kovesdy CP, Quarles LD. Fibroblast growth factor-23: what we know, what we don’t know, and what we need to know. Nephrol Dial Transplant 28: 2228–2236, 2013.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 2228-2236
    • Kovesdy, C.P.1    Quarles, L.D.2
  • 58
    • 84889875899 scopus 로고    scopus 로고
    • The role of fibroblast growth factor-23 in cardiorenal syndrome
    • Kovesdy CP, Quarles LD. The role of fibroblast growth factor-23 in cardiorenal syndrome. Nephron Clin Pract 123: 194–201, 2013.
    • (2013) Nephron Clin Pract , vol.123 , pp. 194-201
    • Kovesdy, C.P.1    Quarles, L.D.2
  • 62
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322: 1561–1566, 1990.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 63
    • 30744445980 scopus 로고    scopus 로고
    • Erdmann J. Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy
    • Lieb W, Graf J, Gotz A, Konig IR, Mayer B, Fischer M, Stritzke J, Hengstenberg C, Holmer SR, Doring A, Lowel H, Schunkert H, Erdmann J. Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy. J Mol Med (Berl) 84: 88–96, 2006.
    • (2006) J Mol Med (Berl) , vol.84 , pp. 88-96
    • Lieb, W.1    Graf, J.2    Gotz, A.3    Konig, I.R.4    Mayer, B.5    Fischer, M.6    Stritzke, J.7    Hengstenberg, C.8    Holmer, S.R.9    Doring, A.10    Lowel, H.11    Schunkert, H.12
  • 64
    • 84860778116 scopus 로고    scopus 로고
    • Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23
    • Lim K, Lu TS, Molostvov G, Lee C, Lam FT, Zehnder D, Hsiao LL. Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23. Circulation 125: 2243–2255, 2012.
    • (2012) Circulation , vol.125 , pp. 2243-2255
    • Lim, K.1    Lu, T.S.2    Molostvov, G.3    Lee, C.4    Lam, F.T.5    Zehnder, D.6    Hsiao, L.L.7
  • 65
    • 0016403709 scopus 로고
    • Accelerated atherosclerosis in prolonged maintenance hemodialysis
    • Lindner A, Charra B, Sherrard DJ, Scribner BH. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med 290: 697–701, 1974.
    • (1974) N Engl J Med , vol.290 , pp. 697-701
    • Lindner, A.1    Charra, B.2    Sherrard, D.J.3    Scribner, B.H.4
  • 66
    • 0141844575 scopus 로고    scopus 로고
    • Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX
    • Liu S, Guo R, Simpson LG, Xiao ZS, Burnham CE, Quarles LD. Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX. J Biol Chem 278: 37419–37426, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 37419-37426
    • Liu, S.1    Guo, R.2    Simpson, L.G.3    Xiao, Z.S.4    Burnham, C.E.5    Quarles, L.D.6
  • 67
    • 34249883939 scopus 로고    scopus 로고
    • How fibroblast growth factor 23 works
    • Liu S, Quarles LD. How fibroblast growth factor 23 works. JAmSoc Nephrol 18: 1637–1647, 2007.
    • (2007) Jamsoc Nephrol , vol.18 , pp. 1637-1647
    • Liu, S.1    Quarles, L.D.2
  • 68
    • 33646367420 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
    • Liu S, Tang W, Zhou J, Stubbs JR, Luo Q, Pi M, Quarles LD. Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 17: 1305–1315, 2006.
    • (2006) J am Soc Nephrol , vol.17 , pp. 1305-1315
    • Liu, S.1    Tang, W.2    Zhou, J.3    Stubbs, J.R.4    Luo, Q.5    Pi, M.6    Quarles, L.D.7
  • 70
    • 0028657576 scopus 로고
    • Cardiac hypertrophy, aortic compliance, peripheral resistance, and wave reflection in end-stage renal disease. Comparative effects of ACE inhibition and calcium channel blockade
    • London GM, Pannier B, Guerin AP, Marchais SJ, Safar ME, Cuche JL. Cardiac hypertrophy, aortic compliance, peripheral resistance, and wave reflection in end-stage renal disease. Comparative effects of ACE inhibition and calcium channel blockade. Circulation 90: 2786–2796, 1994.
    • (1994) Circulation , vol.90 , pp. 2786-2796
    • London, G.M.1    Pannier, B.2    Guerin, A.P.3    Marchais, S.J.4    Safar, M.E.5    Cuche, J.L.6
  • 72
    • 0026751686 scopus 로고
    • Cardiovascular risk factors in chronic renal failure and hemodialysis populations
    • Ma KW, Greene EL, Raij L. Cardiovascular risk factors in chronic renal failure and hemodialysis populations. Am J Kidney Dis 19: 505–513, 1992.
    • (1992) Am J Kidney Dis , vol.19 , pp. 505-513
    • Ma, K.W.1    Greene, E.L.2    Raij, L.3
  • 73
    • 84951570571 scopus 로고    scopus 로고
    • Key role of the kidney in the regulation of fibroblast growth factor 23
    • Mace ML, Gravesen E, Hofman-Bang J, Olgaard K, Lewin E. Key role of the kidney in the regulation of fibroblast growth factor 23. Kidney Int 88: 1304–1313, 2015.
    • (2015) Kidney Int , vol.88 , pp. 1304-1313
    • Mace, M.L.1    Gravesen, E.2    Hofman-Bang, J.3    Olgaard, K.4    Lewin, E.5
  • 74
    • 84856720641 scopus 로고    scopus 로고
    • Regulation and function of the FGF23/klotho endocrine pathways
    • Martin A, David V, Quarles LD. Regulation and function of the FGF23/klotho endocrine pathways. Physiol Rev 92: 131–155, 2012.
    • (2012) Physiol Rev , vol.92 , pp. 131-155
    • Martin, A.1    David, V.2    Quarles, L.D.3
  • 75
    • 80051687775 scopus 로고    scopus 로고
    • Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling
    • Martin A, Liu S, David V, Li H, Karydis A, Feng JQ, Quarles LD. Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J 25: 2551–2562, 2011.
    • (2011) FASEB J , vol.25 , pp. 2551-2562
    • Martin, A.1    Liu, S.2    David, V.3    Li, H.4    Karydis, A.5    Feng, J.Q.6    Quarles, L.D.7
  • 76
    • 84929582868 scopus 로고    scopus 로고
    • Expression of Fgf23 in activated dendritic cells and macrophages in response to immunological stimuli in mice
    • Masuda Y, Ohta H, Morita Y, Nakayama Y, Miyake A, Itoh N, Konishi M. Expression of Fgf23 in activated dendritic cells and macrophages in response to immunological stimuli in mice. Biol Pharm Bull 38: 687–693, 2015.
    • (2015) Biol Pharm Bull , vol.38 , pp. 687-693
    • Masuda, Y.1    Ohta, H.2    Morita, Y.3    Nakayama, Y.4    Miyake, A.5    Itoh, N.6    Konishi, M.7
  • 77
    • 34250325792 scopus 로고    scopus 로고
    • Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis
    • Matakidou A, El GR, Rudd MF, Webb EL, Bridle H, Eisen T, Houlston RS. Further observations on the relationship between the FGFR4 Gly388Arg polymorphism and lung cancer prognosis. Br J Cancer 96: 1904–1907, 2007.
    • (2007) Br J Cancer , vol.96 , pp. 1904-1907
    • Matakidou, A.1    El, G.R.2    Rudd, M.F.3    Webb, E.L.4    Bridle, H.5    Eisen, T.6    Houlston, R.S.7
  • 78
    • 0035797832 scopus 로고    scopus 로고
    • Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril
    • Mathew J, Sleight P, Lonn E, Johnstone D, Pogue J, Yi Q, Bosch J, Sussex B, Probstfield J, Yusuf S. Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril. Circulation 104: 1615–1621, 2001.
    • (2001) Circulation , vol.104 , pp. 1615-1621
    • Mathew, J.1    Sleight, P.2    Lonn, E.3    Johnstone, D.4    Pogue, J.5    Yi, Q.6    Bosch, J.7    Sussex, B.8    Probstfield, J.9    Yusuf, S.10
  • 80
    • 70450230670 scopus 로고    scopus 로고
    • Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
    • Mirza MA, Larsson A, Melhus H, Lind L, Larsson TE. Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population. Atherosclerosis 207: 546–551, 2009.
    • (2009) Atherosclerosis , vol.207 , pp. 546-551
    • Mirza, M.A.1    Larsson, A.2    Melhus, H.3    Lind, L.4    Larsson, T.E.5
  • 84
    • 0030748395 scopus 로고    scopus 로고
    • Cardiovascular abnormalities in patients with X-linked hypophosphatemia
    • Nehgme R, Fahey JT, Smith C, Carpenter TO. Cardiovascular abnormalities in patients with X-linked hypophosphatemia. J Clin Endocrinol Metab 82: 2450–2454, 1997.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2450-2454
    • Nehgme, R.1    Fahey, J.T.2    Smith, C.3    Carpenter, T.O.4
  • 89
    • 84920483737 scopus 로고    scopus 로고
    • Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21
    • Owen BM, Mangelsdorf DJ, Kliewer SA. Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21. Trends Endocrinol Metab 26: 22–29, 2015.
    • (2015) Trends Endocrinol Metab , vol.26 , pp. 22-29
    • Owen, B.M.1    Mangelsdorf, D.J.2    Kliewer, S.A.3
  • 93
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341: 709–717, 1999.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 94
    • 0038678168 scopus 로고    scopus 로고
    • FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization
    • Quarles LD. FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization. Am J Physiol Endocrinol Metab 285: E1–E9, 2003.
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , pp. E1-E9
    • Quarles, L.D.1
  • 95
    • 84859852194 scopus 로고    scopus 로고
    • Role of FGF23 in vitamin D and phosphate metabolism: Implications in chronic kidney disease
    • Quarles LD. Role of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney disease. Exp Cell Res 318: 1040–1048, 2012.
    • (2012) Exp Cell Res , vol.318 , pp. 1040-1048
    • Quarles, L.D.1
  • 96
    • 55949126600 scopus 로고    scopus 로고
    • Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function
    • Rentzsch B, Todiras M, Iliescu R, Popova E, Campos LA, Oliveira ML, Baltatu OC, Santos RA, Bader M. Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function. Hypertension 52: 967–973, 2008.
    • (2008) Hypertension , vol.52 , pp. 967-973
    • Rentzsch, B.1    Todiras, M.2    Iliescu, R.3    Popova, E.4    Campos, L.A.5    Oliveira, M.L.6    Baltatu, O.C.7    Santos, R.A.8    Bader, M.9
  • 98
    • 0036433491 scopus 로고    scopus 로고
    • Serum C-reactive protein and leptin as predictors of kidney disease progression in the Modification of Diet in Renal Disease Study
    • Sarnak MJ, Poindexter A, Wang SR, Beck GJ, Kusek JW, Marco-vina SM, Greene T, Levey AS. Serum C-reactive protein and leptin as predictors of kidney disease progression in the Modification of Diet in Renal Disease Study. Kidney Int 62: 2208–2215, 2002.
    • (2002) Kidney Int , vol.62 , pp. 2208-2215
    • Sarnak, M.J.1    Poindexter, A.2    Wang, S.R.3    Beck, G.J.4    Kusek, J.W.5    Marco-Vina, S.M.6    Greene, T.7    Levey, A.S.8
  • 99
    • 65549124211 scopus 로고    scopus 로고
    • Role of the renin-angiotensin-aldosterone system and inflammatory processes in the development and progression of diastolic dysfunction
    • Sciarretta S, Paneni F, Palano F, Chin D, Tocci G, Rubattu S, Volpe M. Role of the renin-angiotensin-aldosterone system and inflammatory processes in the development and progression of diastolic dysfunction. Clin Sci (Lond) 116: 467–477, 2009.
    • (2009) Clin Sci (Lond) , vol.116 , pp. 467-477
    • Sciarretta, S.1    Paneni, F.2    Palano, F.3    Chin, D.4    Tocci, G.5    Rubattu, S.6    Volpe, M.7
  • 102
    • 84872246782 scopus 로고    scopus 로고
    • Responsiveness of FGF-23 and mineral metabolism to altered dietary phosphate intake in chronic kidney disease (CKD): Results of a randomized trial
    • Sigrist M, Tang M, Beaulieu M, Espino-Hernandez G, Er L, Djurdjev O, Levin A. Responsiveness of FGF-23 and mineral metabolism to altered dietary phosphate intake in chronic kidney disease (CKD): results of a randomized trial. Nephrol Dial Transplant 28: 161–169, 2013.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 161-169
    • Sigrist, M.1    Tang, M.2    Beaulieu, M.3    Espino-Hernandez, G.4    Er, L.5    Djurdjev, O.6    Levin, A.7
  • 103
    • 0024394986 scopus 로고
    • Role of anemia in the pathogenesis of left ventricular hypertrophy in end-stage renal disease
    • Silberberg JS, Rahal DP, Patton DR, Sniderman AD. Role of anemia in the pathogenesis of left ventricular hypertrophy in end-stage renal disease. Am J Cardiol 64: 222–224, 1989.
    • (1989) Am J Cardiol , vol.64 , pp. 222-224
    • Silberberg, J.S.1    Rahal, D.P.2    Patton, D.R.3    Sniderman, A.D.4
  • 109
    • 0034721906 scopus 로고    scopus 로고
    • Human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 275: 33238–33243, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3    Karran, E.4    Christie, G.5    Turner, A.6
  • 111
    • 0035089266 scopus 로고    scopus 로고
    • Prognostic implications of left ventricular hypertrophy
    • Vakili BA, Okin PM, Devereux RB. Prognostic implications of left ventricular hypertrophy. Am Heart J 141: 334–341, 2001.
    • (2001) Am Heart J , vol.141 , pp. 334-341
    • Vakili, B.A.1    Okin, P.M.2    Devereux, R.B.3
  • 112
    • 0025770664 scopus 로고
    • Pathological hypertrophy and cardiac intersti-tium. Fibrosis and renin-angiotensin-aldosterone system
    • Weber KT, Brilla CG. Pathological hypertrophy and cardiac intersti-tium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83: 1849–1865, 1991.
    • (1991) Circulation , vol.83 , pp. 1849-1865
    • Weber, K.T.1    Brilla, C.G.2
  • 113
    • 0141525564 scopus 로고    scopus 로고
    • Serum FGF23 levels in normal and disordered phosphorus homeostasis
    • Weber TJ, Liu S, Indridason OS, Quarles LD. Serum FGF23 levels in normal and disordered phosphorus homeostasis. J Bone Miner Res 18: 1227–1234, 2003.
    • (2003) J Bone Miner Res , vol.18 , pp. 1227-1234
    • Weber, T.J.1    Liu, S.2    Indridason, O.S.3    Quarles, L.D.4
  • 114
  • 119
    • 84871726896 scopus 로고    scopus 로고
    • Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
    • Xie J, Cha SK, An SW, Kuro O, Birnbaumer L, Huang CL. Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart. Nat Commun 3: 1238, 2012.
    • (2012) Nat Commun , vol.3 , pp. 1238
    • Xie, J.1    Cha, S.K.2    An, S.W.3    Kuro, O.4    Birnbaumer, L.5    Huang, C.L.6
  • 124
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
    • Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 281: 15694–15700, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3    Umemori, H.4    Mohammadi, M.5    Ornitz, D.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.