Group II mGluRs suppress hyperexcitability in mouse and human nociceptors

Pain

Volumn 157, Issue 9, 2016, Pages 2081-2088

  Davidson, Steve ^a,d   Golden, Judith P ^a   Copits, Bryan A ^a   Ray, Pradipta R ^b   Vogt, Sherri K ^a   Valtcheva, Manouela V ^a   Schmidt, Robert E ^a   Ghetti, Andrea ^c   Price, Theodore J ^b   Gereau, Robert W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c ANABIOS CORPORATION   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Dorsal root ganglia; Glutamate; Human; Metabotropic; Physiology; Sensitization

Indexed keywords

METABOTROPIC RECEPTOR 2; OPIATE RECEPTOR; PROSTAGLANDIN E2; RNA; AMINO ACID RECEPTOR STIMULATING AGENT; CALCITONIN GENE RELATED PEPTIDE; MESSENGER RNA; METABOTROPIC RECEPTOR; TUBULIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM SENSITIZATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE FIBER; NEWBORN; NONHUMAN; PAIN; PAIN RECEPTOR; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SENSORY NERVE CELL; SKIN; SPINAL CORD DORSAL HORN; SPINAL GANGLION; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; REACTION TIME;

ACTION POTENTIALS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CELLS, CULTURED; DINOPROSTONE; EXCITATORY AMINO ACID AGONISTS; GANGLIA, SPINAL; HUMANS; MICE; MICE, INBRED C57BL; NEURONS; NOCICEPTORS; REACTION TIME; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; TUBULIN;

EID: 84984652736     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000621     Document Type: Article

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