Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice

Pain

Volumn 156, Issue 6, 2015, Pages 1008-1017

  Sdrulla, Andrei D ^a   Xu, Qian ^a   He, Shao Qiu ^a   Tiwari, Vinod ^a   Yang, Fei ^a   Zhang, Chen ^a,b   Shu, Bin ^a   Shechter, Ronen ^a   Raja, Srinivasa N ^a   Wang, Yun ^b   Dong, Xinzhong ^a   Guan, Yun ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

A fiber; Evoked postsynaptic currents; Neuropathic pain; Neurostimulation; Substantia gelatinosa

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMATE DECARBOXYLASE; GLYCINE RECEPTOR; GREEN FLUORESCENT PROTEIN; RED FLUORESCENT PROTEIN; VESICULAR GLUTAMATE TRANSPORTER 2; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR AFFECTING AGENT; BICUCULLINE; PHOTOPROTEIN; SLC17A6 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPOUND ACTION POTENTIAL; DORSAL ROOT; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; INTERNEURON; LATENT PERIOD; LONG TERM DEPRESSION; MALE; MONOSYNAPTIC FORM; MOUSE; NERVE LIGATION; NERVE STIMULATION; NEUROPATHIC PAIN; NEUROTRANSMISSION; NONHUMAN; PAIRED PULSE TEST STIMULATION; POLYSYNAPTIC FORM; PRIORITY JOURNAL; SENSORY NERVE CELL; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; SPINAL CORD SLICE; SPINAL NERVE LIGATION; SUBSTANTIA GELATINOSA; SYNAPTIC TRANSMISSION; WHOLE CELL PATCH CLAMP; YOUNG ADULT; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; NERVE FIBER; NEURALGIA; PATHOLOGY; PATHOPHYSIOLOGY; PERCEPTIVE THRESHOLD; PHYSIOLOGY; POSTERIOR HORN CELL; PROCEDURES; SPINAL CORD; SPINAL NERVE; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; BICUCULLINE; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGENTS; GABA-A RECEPTOR ANTAGONISTS; GLUTAMATE DECARBOXYLASE; GLYCINE AGENTS; GREEN FLUORESCENT PROTEINS; LONG-TERM SYNAPTIC DEPRESSION; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE FIBERS; NEURALGIA; POSTERIOR HORN CELLS; SENSORY THRESHOLDS; SPINAL CORD; SPINAL NERVES; VESICULAR GLUTAMATE TRANSPORT PROTEIN 2;

EID: 84984603918     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/01.j.pain.0000460353.15460.a3     Document Type: Article

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