An organoselenium drug with antioxidant activity and free radical scavenging capacity in vitro

Biological Trace Element Research

Volumn 149, Issue 3, 2012, Pages 399-404

  Ibrahim, Mohammad ^a,b   Hassan, Waseem ^a,c   Deobald, Anna Maria ^d   Braga, Antonio Luis ^e   Rocha, Joao B T ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b ABDUL WALI KHAN UNIVERSITY   (Pakistan)

^c UNIVERSITY OF PESHAWAR   (Pakistan)

^d FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^e FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

(PhSe)2; Antioxidant; DPPH; Lipid peroxidation; Oxidative stress

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; AMINE; DIARYL DISELENIDE; DIPHENYL DISELENIDE; FERROUS ION; FERROUS SULFATE; N (4 METHYLBENZYLIDENE) 1 [2 [[2 [1 (4 METHYL BENZYLIDENEAMINO)ETHYL]PHENYL]DISELANYL]PHENYL]ETHANAMINE; NITROPRUSSIDE SODIUM; ORGANOSELENIUM DERIVATIVE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; FREE RADICAL SCAVENGING CAPACITY; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

RATTUS;

EID: 84984586811     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9440-7     Document Type: Article

References (31)

1. Azbill RD, Mu XJ, BruceKeller AJ, Mattson MP, Springer JE (1997) Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury. Brain Res 765:283-290
2. Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97:1634-1658
3. Santamaría A, Salvatierra-Sanchez R, Vazquez-Roman B, Santiago-Lopez D, Villeda-Hernandez J, Galvan-Arzates S, Jimenez-Capdeville ME, Ali SF (2003) Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vitro and in vivo studies. J Neurochem 86:479-488
4. Morrissey PA, O'Brien NM (1998) Dietary antioxidants in health and disease. Int Dairy J 8:463-472
5. Naziroglu M (2009) Role of selenium on calcium signaling and oxidative stress-induced molecular pathways in epilepsy. Neurochem Res 34:2181-2191
6. Steinbrenner H, Sies H (2009) Protection against reactive oxygen species by selenoproteins. Biochim Biophys Acta 1790:1478-1485
7. Nogueira CW, Zeni G, Rocha JBT (2004) Organoselenium and organotellurium compounds: toxicology and pharmacology. Chem Rev 104:6255-6285
8. Parnham MJ, Graf E (1991) Pharmacology of synthetic organic selenium compounds. Progress in Drug Res 36:9-47
9. Saito I, Asano T, Sano K, Takakura K, Abe H, Yoshimoto T, Kikuchi H, Ohta T, Ishibashi S (1998) Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery 42:269-277
10. Kondoh S, Nagasawa S, Kawanishi M, Yamaguchi K, Kajimoto S, Ohta T (1999) Effects of ebselen on cerebral ischemia and reperfusion evaluated by microdialysis. Neurological Res 21:682-686
11. Imai H, Graham DI, Masayasu H, Macrae IM (2003) Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia. Free Radic Biol Med 34:56-63
12. Wilson SR, Zucker PA, Huang RRC, Spector A (1989) Development of synthetic compound with glutathione peroxidase activity. J Am Chem Soc 111:5936-5939
13. Chaudiere J, Courtin O, Leclaire J (1992) Glutathione oxidase activity of selenocystamine: a mechanistic study. Biochem Biophys 296:328-336
14. Rossato JI, Ketzer LA, Centurião FB, Silva SJN, Lüdtke DS, Zeni G, Braga AL, Rubin MA, Rocha JBT (2002) Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain. Neurochem Res 27:297-303
15. Hassan W, Ibrahim M, Nogueira CW, Braga AL, Mohammad Zai IU, Taube PS, Rocha JBT (2009) Enhancement of iron-catalyzed lipid peroxidation by acidosis in brain homogenate: comparative effect of diphenyl diselenide and ebselen. Brain Res 1258:71-77
16. Braga AL, Paixão MW, Marin G (2005) Seleno-imine: a new class of versatile, modular N, Se ligands for asymmetric palladiumcatalyzed allylic alkylation. Synlett 11:1675-1678
17. Liu D, Dai Q, Zhang X (2005) A new class of readily available and conformationally rigid phosphino-oxazoline ligands for asymmetric catalysis. Tetrahedron 61:6460-6471
18. Paulmier C (1986) Synthesis and properties of selenide. In: Baldwin JE (ed) Selenium reagents and intermediates in organic synthesis. Pergamon, Oxford, pp 84-116
19. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 95:351-358
20. Choi CW, Kim SC, Hwang SS, Choi BK, Ahn HJ, Lee MY, Park SH, Kim SK (2002) Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison. Plant Sci 153:1161-1168
21. Talas ZS, Ozdemir I, Yilmaz I, Gok Y, ve Orun I (2008) The investigation of the antioxidative properties of the novel synthetic organoselenium compounds in some rat tissues. Exp Biol Med 233:575-579
22. Talas ZS, Yilmaz I, Ozdemir I, Ates B, Gok Y, Cetinkaya B (2009) Role of synthesised organoselenium compounds on protection of rat erythrocytes from DMBA-induced oxidative stress. Biol Trace Elem Res 128:167-175
23. Talas ZS, Bayraktar N, Ozdemir I, Gok Y, Yilmaz I (2009) The effects of synthetic organoselenium compounds on nitric oxide levels in DMBA-induced rat liver. J Environ Biol 30:591-593
24. Ozdemir I, Talas ZS, Gok Y, Ates B, Yilmaz I (2010) Changes in tyrosine hydroxylase activity, adrenomedullin and total RNA levels by treatment of organoselenium compounds in rat hypothalamus exposed to DMBA. Fresenius Environmental Bulletin 19 (4a):664-668
25. Graf E, Mahoney JR, Bryant RG, Eaton JW (1984) Iron catalyzed hydroxyl radical formation: stringent requirement for free iron coordination site. J Biol Chem 259:3620-3624
26. Klebanoff SJ, Gally JI, Goldstein IM, Snyderman R (eds) (1992) Oxygen metabolites from phagocytes. Raven, New York, pp 541-588
27. Arnold WP, Longneeker DE, Epstein RM (1984) Photodegradation of sodium nitroprusside: biologic activity and cyanide release. Anesthesiology 61:254-260
28. Bates JNMT, Guerra R, Harrison DG (1990) Nitric oxide generation from nitroprusside by vascular tissue. Biochem Pharmacol 42:157-165
29. Bolanos J, Almeida A (1999) Roles of nitric oxide in brain hypoxia- ischemia. Biochim Biophys Acta 1411:415-436
30. Ogunmoyole RJBT, Okoronkwo AE, Kade IJ (2009) Altered pH homeostasis modulates the glutathione peroxidase mimics and other antioxidant properties of diphenyl diselenide. Chem Biol Interact 23:106-11
31. Valko M, Izakovic M, Mazur M, Rhodes CJ, Telser J (2004) Role of oxygen radicals 545 in DNA damage and cancer incidence. Mol Cell Biochem 266:37-56