메뉴 건너뛰기




Volumn 503, Issue 1, 2011, Pages 1-5

Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: A pathway for their neuroprotective effects

Author keywords

Diphenyl diselenide; Ebselen; Selenium compounds; Thioredoxin reductase (TrxR)

Indexed keywords

2,4,6,2',4',6' HEXAMETHYLDIPHENYL DISELENIDE; 4,4' BISCHLORODIPHENYL DISELENIDE; 4,4' BISMETHOXYDIPHENYL DISELENIDE; 4,4' BISTRIFLUOROMETHYLDIPHENYL DISELENIDE; 4.4' BISCARBOXY DIPHENYL DISELENIDE; DIPHENYL DISELENIDE; EBSELEN; GLUTATHIONE PEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

EID: 84984550859     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.07.050     Document Type: Article
Times cited : (66)

References (26)
  • 1
    • 67349120863 scopus 로고    scopus 로고
    • Focus on mammalian thioredoxin reductases - important selenoproteins with versatile functions
    • Arnér E.S.J. Focus on mammalian thioredoxin reductases - important selenoproteins with versatile functions. Biochim. Biophys. Acta 2009, 1790:495-526.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 495-526
    • Arnér, E.S.J.1
  • 4
    • 79955853681 scopus 로고    scopus 로고
    • Biomarkers of oxidative stress in ruminant medicine
    • Celi P. Biomarkers of oxidative stress in ruminant medicine. Immunopharmacol. Immunotoxicol. 2011, 33:233-240.
    • (2011) Immunopharmacol. Immunotoxicol. , vol.33 , pp. 233-240
    • Celi, P.1
  • 5
    • 0028819079 scopus 로고
    • The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat
    • Dawson D.A., Masayasu H., Graham D.I., Macrae I.M. The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat. Neurosci. Lett. 1995, 185:65-69.
    • (1995) Neurosci. Lett. , vol.185 , pp. 65-69
    • Dawson, D.A.1    Masayasu, H.2    Graham, D.I.3    Macrae, I.M.4
  • 6
    • 84984535996 scopus 로고    scopus 로고
    • Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity
    • de Freitas A.S., Prestes A.S., Wagner C., Sudati J.H., Alves D., Porciúncula L.O., Kade I.J., Rocha J.B.T. Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity. Molecules 2010, 15:7699-7714.
    • (2010) Molecules , vol.15 , pp. 7699-7714
    • de Freitas, A.S.1    Prestes, A.S.2    Wagner, C.3    Sudati, J.H.4    Alves, D.5    Porciúncula, L.O.6    Kade, I.J.7    Rocha, J.B.T.8
  • 7
    • 47749136973 scopus 로고    scopus 로고
    • Neuroprotective effects of selenium and ginkgo biloba extract (EGb761) against ischemia and reperfusion injury in rat brain
    • Erbil G., Ozbal S., Sonmez U., Perkcetin C., Tugyan K., Bagriyanik A., Ozogul C. Neuroprotective effects of selenium and ginkgo biloba extract (EGb761) against ischemia and reperfusion injury in rat brain. Neurosciences 2008, 13:233-238.
    • (2008) Neurosciences , vol.13 , pp. 233-238
    • Erbil, G.1    Ozbal, S.2    Sonmez, U.3    Perkcetin, C.4    Tugyan, K.5    Bagriyanik, A.6    Ozogul, C.7
  • 8
    • 84984589194 scopus 로고    scopus 로고
    • Oxidative stress in MeHg-induced neurotoxicity
    • doi:10.1016/j.taap%202011.05.001
    • M. Farina, M. Aschner, J.B.T. Rocha, Oxidative stress in MeHg-induced neurotoxicity, Toxicol. Appl. Pharmacol., doi:10.1016/j.taap%202011.05.001.
    • Toxicol. Appl. Pharmacol.
    • Farina, M.1    Aschner, M.2    Rocha, J.B.T.3
  • 9
    • 79955536653 scopus 로고    scopus 로고
    • Selenol protecting groups in organic chemistry: special emphasis on selenocysteine Se-protection in solid phase peptide synthesis
    • Flemer S. Selenol protecting groups in organic chemistry: special emphasis on selenocysteine Se-protection in solid phase peptide synthesis. Molecules 2011, 16:3232-3251.
    • (2011) Molecules , vol.16 , pp. 3232-3251
    • Flemer, S.1
  • 10
    • 80051635783 scopus 로고    scopus 로고
    • Iron-dependet functions of mitochondria-relation to neurodegereration
    • Gille G., Reichmann H. Iron-dependet functions of mitochondria-relation to neurodegereration. J. Neural Transm. 2011, 118:349-359.
    • (2011) J. Neural Transm. , vol.118 , pp. 349-359
    • Gille, G.1    Reichmann, H.2
  • 14
    • 77955253261 scopus 로고    scopus 로고
    • Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione-S-transferase-like activity dependent on the glutathione content
    • Luchese C., Nogueira C.W. Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione-S-transferase-like activity dependent on the glutathione content. J. Pharm. Pharmacol. 2010, 62:1146-1151.
    • (2010) J. Pharm. Pharmacol. , vol.62 , pp. 1146-1151
    • Luchese, C.1    Nogueira, C.W.2
  • 16
    • 0035385139 scopus 로고    scopus 로고
    • Chemistry of biologically important synthetic organoselenium compounds
    • Mugesh G., Dumont W.W., Sies H. Chemistry of biologically important synthetic organoselenium compounds. Chem. Rev. 2001, 101:2125-2179.
    • (2001) Chem. Rev. , vol.101 , pp. 2125-2179
    • Mugesh, G.1    Dumont, W.W.2    Sies, H.3
  • 17
    • 84984583119 scopus 로고    scopus 로고
    • Organoselenium and organotellurium compounds: pharmacology and toxicology
    • Nogueira C.W., Zeni G., Rocha J.B. Organoselenium and organotellurium compounds: pharmacology and toxicology. Chem. Rev. 2004, 104:6255-6286.
    • (2004) Chem. Rev. , vol.104 , pp. 6255-6286
    • Nogueira, C.W.1    Zeni, G.2    Rocha, J.B.3
  • 18
    • 84984537101 scopus 로고    scopus 로고
    • Diphenyl Diselenide a janus-faced molecule
    • Nogueira C.W., Rocha J.B.T., Diphenyl Diselenide a janus-faced molecule. J. Braz. Chem. Soc. 2010, 21:2055-2071.
    • (2010) J. Braz. Chem. Soc. , vol.21 , pp. 2055-2071
    • Nogueira, C.W.1    Rocha, J.B.T.2
  • 19
    • 84984580672 scopus 로고    scopus 로고
    • Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds
    • doi:10.1007/s00204-011-0720-3
    • C.W. Nogueira, J.B.T. Rocha, Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds, Arch. Toxicol., doi:10.1007/s00204-011-0720-3.
    • Arch. Toxicol.
    • Nogueira, C.W.1    Rocha, J.B.T.2
  • 20
    • 44349136796 scopus 로고    scopus 로고
    • The effects of selenium against cerebral ischemia-reperfusion injury in rats
    • Ozbal S., Erbil G., Kocdor H., Tugyan K., Pekcetin C., Ozogul C. The effects of selenium against cerebral ischemia-reperfusion injury in rats. Neurosci. Lett. 2008, 483:265-269.
    • (2008) Neurosci. Lett. , vol.483 , pp. 265-269
    • Ozbal, S.1    Erbil, G.2    Kocdor, H.3    Tugyan, K.4    Pekcetin, C.5    Ozogul, C.6
  • 22
    • 0031886421 scopus 로고    scopus 로고
    • Neuroprotective effect of an antioxidant, ebselen, delayed neurological deficits after aneurysmal subarachnoid hemorrhage
    • Saito I., Asano T., Takakura K., Abe H., Yoshimoto T., Kikichi H., Ohta T., Ishibashi S. Neuroprotective effect of an antioxidant, ebselen, delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery 1998, 42:269-277.
    • (1998) Neurosurgery , vol.42 , pp. 269-277
    • Saito, I.1    Asano, T.2    Takakura, K.3    Abe, H.4    Yoshimoto, T.5    Kikichi, H.6    Ohta, T.7    Ishibashi, S.8
  • 23
    • 72649102374 scopus 로고    scopus 로고
    • Protection against reactive oxygen species by selenoproteins
    • Steinbrenner H., Sies H. Protection against reactive oxygen species by selenoproteins. Biochim. Biophys. Acta 2009, 1790:1478-1485.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1478-1485
    • Steinbrenner, H.1    Sies, H.2
  • 25
    • 0037131424 scopus 로고    scopus 로고
    • A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase
    • Zhao R., Holmgren A. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. J. Biol. Chem. 2002, 277:39456-39462.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39456-39462
    • Zhao, R.1    Holmgren, A.2
  • 26
    • 0037172997 scopus 로고    scopus 로고
    • A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
    • Zhao R., Masayasu H., Holmgren A., Ebselen A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:8579-8584.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 8579-8584
    • Zhao, R.1    Masayasu, H.2    Holmgren, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.