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Volumn 7, Issue 34, 2016, Pages 54838-54851

MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A

Author keywords

Lactate dehydrogenase A(LDHA); LC MS MS; MiR 34b 3; MiR449a; Nasopharyngeal carcinoma

Indexed keywords

LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; MICRORNA; MICRORNA 34B 3; MICRORNA 449A; UNCLASSIFIED DRUG; ISOENZYME; LACTATE DEHYDROGENASE 5; MIRN34 MICRORNA, HUMAN; MIRN449 MICRORNA, HUMAN; PROTEOME;

EID: 84983527709     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10761     Document Type: Article
Times cited : (30)

References (64)
  • 1
    • 0036435155 scopus 로고    scopus 로고
    • Epidemiology of nasopharyngeal carcinoma
    • Yu MC, Yuan J. Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol. 2002; 12:421-429.
    • (2002) Semin Cancer Biol , vol.12 , pp. 421-429
    • Yu, M.C.1    Yuan, J.2
  • 6
    • 84929264308 scopus 로고    scopus 로고
    • MicroRNA-93 promotes cell growth and invasion in nasopharyngeal carcinoma by targeting disabled homolog-2
    • Xu YF, Mao YP, Li YQ, Ren XY, He QM, Tang X, Sun Y, Liu N, Ma J. MicroRNA-93 promotes cell growth and invasion in nasopharyngeal carcinoma by targeting disabled homolog-2. Cancer Lett. 2015; 363:146-155.
    • (2015) Cancer Lett , vol.363 , pp. 146-155
    • Xu, Y.F.1    Mao, Y.P.2    Li, Y.Q.3    Ren, X.Y.4    He, Q.M.5    Tang, X.6    Sun, Y.7    Liu, N.8    Ma, J.9
  • 8
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Baetel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Baetel, D.P.1
  • 14
    • 84862796512 scopus 로고    scopus 로고
    • An in silicoanalysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma
    • Luo Z, Zhang L, Li Z, Li X, Li G, Yu H, Jiang C, Dai Y, Guo X, Xiang J, Li G. An in silicoanalysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma. BMC Med Genomics. 2012; 5:3.
    • (2012) BMC Med Genomics , vol.5 , pp. 3
    • Luo, Z.1    Zhang, L.2    Li, Z.3    Li, X.4    Li, G.5    Yu, H.6    Jiang, C.7    Dai, Y.8    Guo, X.9    Xiang, J.10    Li, G.11
  • 18
    • 84941947679 scopus 로고    scopus 로고
    • Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues
    • Wan XX, Yi H, Qu JQ, He QY, Xiao ZQ. Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues. Oncol Rep. 2015; 34:2585-2601.
    • (2015) Oncol Rep , vol.34 , pp. 2585-2601
    • Wan, X.X.1    Yi, H.2    Qu, J.Q.3    He, Q.Y.4    Xiao, Z.Q.5
  • 22
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 2010; 17:193-199.
    • (2010) Cell Death Differ , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 23
    • 37049010980 scopus 로고    scopus 로고
    • The guardian's little helper: microRNAs in the p53 tumor suppressor network
    • He X, He L, GJ H. The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Research. 2007; 67:11099-11101.
    • (2007) Cancer Research , vol.67 , pp. 11099-11101
    • He, X.1    He, L.2    Hannon, G.J.3
  • 26
    • 84978858615 scopus 로고    scopus 로고
    • MiR-29c regulates the expression of miR-34c and miR-449a by targeting DNA methyltransferase 3a and 3b in nasopharyngeal carcinoma
    • Niu M, Gao D, Wen Q, Wei P, Pan S, Shuai C, Ma H, Xiang J, Li Z, Fan S, Li G, Peng S. MiR-29c regulates the expression of miR-34c and miR-449a by targeting DNA methyltransferase 3a and 3b in nasopharyngeal carcinoma. BMC Cancer. 2016; 16:218.
    • (2016) BMC Cancer , vol.16 , pp. 218
    • Niu, M.1    Gao, D.2    Wen, Q.3    Wei, P.4    Pan, S.5    Shuai, C.6    Ma, H.7    Xiang, J.8    Li, Z.9    Fan, S.10    Li, G.11    Peng, S.12
  • 27
    • 84862680867 scopus 로고    scopus 로고
    • MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway
    • Bao J, Li D, Wang L, Wu J, Hu Y, Wang Z, Chen Y, Cao X, Jiang C, Yan W, Xu C. MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway. J Biol Chem. 2012; 287:21686-21698.
    • (2012) J Biol Chem , vol.287 , pp. 21686-21698
    • Bao, J.1    Li, D.2    Wang, L.3    Wu, J.4    Hu, Y.5    Wang, Z.6    Chen, Y.7    Cao, X.8    Jiang, C.9    Yan, W.10    Xu, C.11
  • 28
    • 84979691979 scopus 로고    scopus 로고
    • mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice
    • Yuan S, Tang C, Zhang Y, Wu J, Bao J, Zheng H, Xu C, Yan W. mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice. Biol Open. 2015; 4:212-223. 29. Shi M, Cui J, Du J, Wei D, Jia Z, Zhang J, Zhu Z, Gao Y, Xie K. A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer. Clin Cancer Res. 2014; 20:4370-4380.
    • (2015) Biol Open , vol.4 , pp. 212-223
    • Yuan, S.1    Tang, C.2    Zhang, Y.3    Wu, J.4    Bao, J.5    Zheng, H.6    Xu, C.7    Yan, W.8
  • 29
    • 84905979612 scopus 로고    scopus 로고
    • A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer
    • Shi M, Cui J, Du J, Wei D, Jia Z, Zhang J, Zhu Z, Gao Y, Xie K. A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer. Clin Cancer Res. 2014; 20:4370-4380.
    • (2014) Clin Cancer Res , vol.20 , pp. 4370-4380
    • Shi, M.1    Cui, J.2    Du, J.3    Wei, D.4    Jia, Z.5    Zhang, J.6    Zhu, Z.7    Gao, Y.8    Xie, K.9
  • 30
    • 84901036434 scopus 로고    scopus 로고
    • FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression
    • Cui J, Shi M, Xie D, Wei D, Jia Z, Zheng S, Gao Y, Huang S, Xie K. FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression. Clin Cancer Res. 2014; 20:2595-2606.
    • (2014) Clin Cancer Res , vol.20 , pp. 2595-2606
    • Cui, J.1    Shi, M.2    Xie, D.3    Wei, D.4    Jia, Z.5    Zheng, S.6    Gao, Y.7    Huang, S.8    Xie, K.9
  • 31
    • 84878678600 scopus 로고    scopus 로고
    • Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells
    • Rong Y, Wu W, Ni X, Kuang T, Jin D, Wang D, Lou W. Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells. Tumour Biol. 2013; 34:1523-1530.
    • (2013) Tumour Biol , vol.34 , pp. 1523-1530
    • Rong, Y.1    Wu, W.2    Ni, X.3    Kuang, T.4    Jin, D.5    Wang, D.6    Lou, W.7
  • 33
    • 84872790592 scopus 로고    scopus 로고
    • LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma
    • Yao F, Zhao T, Zhong C, Zhu J, Zhao H. LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma. Tumour Biol. 2013; 34:25-31.
    • (2013) Tumour Biol , vol.34 , pp. 25-31
    • Yao, F.1    Zhao, T.2    Zhong, C.3    Zhu, J.4    Zhao, H.5
  • 36
    • 84940897675 scopus 로고    scopus 로고
    • Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells
    • Lo AK, Dawson CW, Young LS, Ko CW, Hau PM, Lo KW. Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells. J Pathol. 2015.
    • (2015) J Pathol
    • Lo, A.K.1    Dawson, C.W.2    Young, L.S.3    Ko, C.W.4    Hau, P.M.5    Lo, K.W.6
  • 38
    • 84920006718 scopus 로고    scopus 로고
    • Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells
    • Yang Y, Su D, Zhao L, Zhang D, Xu J, Wan J, Fan S, Chen M. Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells. Oncotarget. 2014; 5:11886-11896. doi: 10.18632/oncotarget.2620.
    • (2014) Oncotarget , vol.5 , pp. 11886-11896
    • Yang, Y.1    Su, D.2    Zhao, L.3    Zhang, D.4    Xu, J.5    Wan, J.6    Fan, S.7    Chen, M.8
  • 41
    • 84901343588 scopus 로고    scopus 로고
    • Prognostic value of pretreatment serum levels of lactate dehydrogenase in nonmetastatic nasopharyngeal carcinoma: single-site analysis of 601 patients in a highly endemic area
    • Wei Z, Zeng X, Xu J, Duan X, Xie Y. Prognostic value of pretreatment serum levels of lactate dehydrogenase in nonmetastatic nasopharyngeal carcinoma: single-site analysis of 601 patients in a highly endemic area. Onco Targets Ther. 2014; 7:739-749.
    • (2014) Onco Targets Ther , vol.7 , pp. 739-749
    • Wei, Z.1    Zeng, X.2    Xu, J.3    Duan, X.4    Xie, Y.5
  • 42
    • 84876134099 scopus 로고    scopus 로고
    • Serum lactic dehydrogenase strongly predicts survival in metastatic nasopharyngeal carcinoma treated with palliative chemotherapy
    • Jin Y, Ye X, Shao L, Lin BC, He CX, Zhang BB, Zhang YP. Serum lactic dehydrogenase strongly predicts survival in metastatic nasopharyngeal carcinoma treated with palliative chemotherapy. Eur J Cancer. 2013; 49:1619-1626
    • (2013) Eur J Cancer , vol.49 , pp. 1619-1626
    • Jin, Y.1    Ye, X.2    Shao, L.3    Lin, B.C.4    He, C.X.5    Zhang, B.B.6    Zhang, Y.P.7
  • 43
    • 84959484939 scopus 로고    scopus 로고
    • Prognostic implications of dynamic serum lactate dehydrogenase assessments in nasopharyngeal carcinoma patients treated with intensitymodulated radiotherapy
    • Zhou GQ, Ren XY, Mao YP, Chen L, Sun Y, Liu LZ, Li L, Lin AH, Mai HQ, Ma J. Prognostic implications of dynamic serum lactate dehydrogenase assessments in nasopharyngeal carcinoma patients treated with intensitymodulated radiotherapy. Sci Rep. 2016; 6:22326.
    • (2016) Sci Rep , vol.6 , pp. 22326
    • Zhou, G.Q.1    Ren, X.Y.2    Mao, Y.P.3    Chen, L.4    Sun, Y.5    Liu, L.Z.6    Li, L.7    Lin, A.H.8    Mai, H.Q.9    Ma, J.10
  • 44
    • 84892411852 scopus 로고    scopus 로고
    • Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells
    • Zhai X, Yang Y, Wan J, Zhu R, Wu Y. Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol Rep. 2013; 30:2983-2991.
    • (2013) Oncol Rep , vol.30 , pp. 2983-2991
    • Zhai, X.1    Yang, Y.2    Wan, J.3    Zhu, R.4    Wu, Y.5
  • 45
    • 84885028952 scopus 로고    scopus 로고
    • Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate
    • Li X, Lu W, Hu Y, Wen S, Qian C, Wu W, Huang P. Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate. Int J Oncol. 2013.
    • (2013) Int J Oncol
    • Li, X.1    Lu, W.2    Hu, Y.3    Wen, S.4    Qian, C.5    Wu, W.6    Huang, P.7
  • 46
    • 84912122688 scopus 로고    scopus 로고
    • The analysis of microRNA-34 family expression in human cancer studies comparing cancer tissues with corresponding pericarcinous tissues
    • Wang L, Yu J, Xu J, Zheng C, Li X, Du J. The analysis of microRNA-34 family expression in human cancer studies comparing cancer tissues with corresponding pericarcinous tissues. Gene. 2015; 554:1-8.
    • (2015) Gene , vol.554 , pp. 1-8
    • Wang, L.1    Yu, J.2    Xu, J.3    Zheng, C.4    Li, X.5    Du, J.6
  • 48
    • 84869219338 scopus 로고    scopus 로고
    • miR-34-a microRNA replacement therapy is headed to the clinic
    • Bader AG. miR-34-a microRNA replacement therapy is headed to the clinic. Front Genet. 2012; 3:120.
    • (2012) Front Genet , vol.3 , pp. 120
    • Bader, A.G.1
  • 49
    • 84904341198 scopus 로고    scopus 로고
    • Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis
    • Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W. Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014; 111:E2851-E2857.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. E2851-E2857
    • Wu, J.1    Bao, J.2    Kim, M.3    Yuan, S.4    Tang, C.5    Zheng, H.6    Mastick, G.S.7    Xu, C.8    Yan, W.9
  • 52
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warbuge O. On the origin of cancer cells. Science. 1956; 123:309-14.
    • (1956) Science , vol.123 , pp. 309-314
    • Warbuge, O.1
  • 53
    • 33744826296 scopus 로고    scopus 로고
    • Cancer's sweet tooth
    • Bui T, Thompson CB. Cancer's sweet tooth. Cancer Cell. 2006; 9:419-420.
    • (2006) Cancer Cell , vol.9 , pp. 419-420
    • Bui, T.1    Thompson, C.B.2
  • 54
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander HM, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009; 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander, H.M.1    Cantley, L.C.2    Thompson, C.B.3
  • 56
    • 84955671082 scopus 로고    scopus 로고
    • The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor
    • Valvona CJ, Fillmore HL, Nunn PB, Pilkington GJ. The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor. Brain Pathol. 2016; 26:3-17.
    • (2016) Brain Pathol , vol.26 , pp. 3-17
    • Valvona, C.J.1    Fillmore, H.L.2    Nunn, P.B.3    Pilkington, G.J.4
  • 57
    • 34547504562 scopus 로고    scopus 로고
    • Serum lactate dehydrogenase level is a prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy
    • Turen S, Ozyar E, Altundag K, Gullu I, Atahan IL. Serum lactate dehydrogenase level is a prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy. Cancer Invest. 2007; 25:315-321.
    • (2007) Cancer Invest , vol.25 , pp. 315-321
    • Turen, S.1    Ozyar, E.2    Altundag, K.3    Gullu, I.4    Atahan, I.L.5
  • 58
    • 84940897675 scopus 로고    scopus 로고
    • Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells
    • Lo AK, Dawson CW, Young LS, Ko CW, Hau PM, Lo KW. Activation of the FGFR1 signalling pathway by the Epstein-Barr virus-encoded LMP1 promotes aerobic glycolysis and transformation of human nasopharyngeal epithelial cells. J Pathol. 2015; 237:238-248.
    • (2015) J Pathol , vol.237 , pp. 238-248
    • Lo, A.K.1    Dawson, C.W.2    Young, L.S.3    Ko, C.W.4    Hau, P.M.5    Lo, K.W.6
  • 59
    • 84888433384 scopus 로고    scopus 로고
    • Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapy
    • Miao P, Sheng S, Sun X, Liu J, Huang G. Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapy. Iubmb Life. 2013; 65:904-910.
    • (2013) Iubmb Life , vol.65 , pp. 904-910
    • Miao, P.1    Sheng, S.2    Sun, X.3    Liu, J.4    Huang, G.5
  • 60
    • 84939248200 scopus 로고    scopus 로고
    • Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer
    • Wang J, Wang H, Liu A, Fang C, Hao J, Wang Z. Lactate dehydrogenase A negatively regulated by miRNAs promotes aerobic glycolysis and is increased in colorectal cancer. Oncotarget. 2015; 6:19456-19468. doi: 10.18632/oncotarget.3318.
    • (2015) Oncotarget , vol.6 , pp. 19456-19468
    • Wang, J.1    Wang, H.2    Liu, A.3    Fang, C.4    Hao, J.5    Wang, Z.6
  • 61
    • 84947735943 scopus 로고    scopus 로고
    • miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus
    • Mi Y, Guo N, He T, Ji J, Li Z, Huang P. miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus. J Mol Endocrinol. 2015; 55:219-229.
    • (2015) J Mol Endocrinol , vol.55 , pp. 219-229
    • Mi, Y.1    Guo, N.2    He, T.3    Ji, J.4    Li, Z.5    Huang, P.6
  • 62
    • 71549117585 scopus 로고    scopus 로고
    • Combination of FASP, StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome
    • Wisniewski JR, Zougman A, Mann M. Combination of FASP, StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome. J Proteome Res. 2009; 8:5674-5678.
    • (2009) J Proteome Res , vol.8 , pp. 5674-5678
    • Wisniewski, J.R.1    Zougman, A.2    Mann, M.3
  • 63
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Rappsilber J, Ishihama Y, Mann M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal Chem. 2003; 75:663-670.
    • (2003) Anal Chem , vol.75 , pp. 663-670
    • Rappsilber, J.1    Ishihama, Y.2    Mann, M.3
  • 64
    • 33645774852 scopus 로고    scopus 로고
    • Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics
    • Ishihama Y, Rappsilber J, Mannon M. Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics. J Proteome Res. 2006; 5:988-994.
    • (2006) J Proteome Res , vol.5 , pp. 988-994
    • Ishihama, Y.1    Rappsilber, J.2    Mannon, M.3


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