Mitochondrial p53 contributes to reovirus-induced neuronal apoptosis and central nervous system injury in a mouse model of viral encephalitis

Journal of Virology

Volumn 90, Issue 17, 2016, Pages 7684-7691

  Zhuang, Yonghua ^a   Berens Norman, Heather M ^b   Smith Leser, J ^a   Clarke, Penny ^a   Tyler, Kenneth L ^a,c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN BAK; PROTEIN P53; BAK1 PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOACCUMULATION; BRAIN LEVEL; BRAIN SLICE; CENTRAL NERVOUS SYSTEM DISEASE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; EX VIVO STUDY; MITOCHONDRION; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REOVIRIDAE; SURVIVAL RATE; UPREGULATION; VIRUS ENCEPHALITIS; VIRUS GENE; VIRUS IDENTIFICATION; ANIMAL; DISEASE MODEL; HOST PATHOGEN INTERACTION; METABOLISM; NERVE CELL; PATHOGENICITY; PATHOLOGY; PROTEIN ANALYSIS; REOVIRUS INFECTION; VIROLOGY;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, VIRAL; HOST-PATHOGEN INTERACTIONS; MICE; MITOCHONDRIA; NEURONS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; REOVIRIDAE; REOVIRIDAE INFECTIONS; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84983509372     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00583-16     Document Type: Article

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