Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection

Journal of NeuroVirology

Volumn 17, Issue 4, 2011, Pages 314-326

  Dionne, Kalen R ^a   Galvin, John M ^b   Schittone, Stephanie A ^a   Clarke, Penny ^b   Tyler, Kenneth L ^a,b,c  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Brain; Encephalitis; Interferon; Reovirus; Tropism; Virus

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERFERON; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD; BRAIN INJURY; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE SEVERITY; EPENDYMA; HEART; HOST RESISTANCE; INTESTINE INJURY; KIDNEY; LETHALITY; LIVER; LIVER INJURY; MENINX; MOUSE; NONHUMAN; ORTHOMYXOVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REOVIRUS; REOVIRUS INFECTION; SEROTYPE; SIGNAL TRANSDUCTION; SPLEEN; VIRAL TROPISM; VIRUS REPLICATION; WILD TYPE;

ANIMALS; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GTP-BINDING PROTEINS; HEART; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE I; INTERFERON-ALPHA; INTERFERON-BETA; KIDNEY; LIVER; MICE; MICE, KNOCKOUT; NEUROGLIA; NEURONS; ORTHOREOVIRUS, MAMMALIAN; RECEPTOR, INTERFERON ALPHA-BETA; REOVIRIDAE INFECTIONS; SIGNAL TRANSDUCTION; SPLEEN; SURVIVAL RATE; VIRAL TROPISM; VIRUS REPLICATION;

MUS; ORTHOMYXOVIRIDAE; ORTHOREOVIRUS;

EID: 80054764780     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-011-0038-1     Document Type: Article

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