Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles

ACS Nano

Volumn 10, Issue 8, 2016, Pages 7721-7730

  Cheng, Liang ^a,b   Kamkaew, Anyanee ^b   Sun, Haiyan ^b   Jiang, Dawei ^b   Valdovinos, Hector F ^c   Gong, Hua ^a   England, Christopher G ^c   Goel, Shreya ^b   Barnhart, Todd E ^c   Cai, Weibo ^b,c  

^a SOOCHOW UNIVERSITY   (China)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

EPR effect; fluorescence imaging; PEG Ce 6 nanomicelles; PET imaging; photodynamic therapy

Indexed keywords

CHELATION; DIAGNOSIS; DISEASES; FLUORESCENCE; MEDICAL NANOTECHNOLOGY; ONCOLOGY; PHOTODYNAMIC THERAPY; POSITRONS; TUMORS;

EPR EFFECT; FLUORESCENCE IMAGING; INTRAVENOUS INJECTIONS; MULTI-FUNCTIONAL NANOPARTICLES; NANOMICELLES; PET IMAGING; PHOTODYNAMIC THERAPY (PDT); POSITRON EMISSION TOMOGRAPHY (PET);

POSITRON EMISSION TOMOGRAPHY;

NANOPARTICLE; PHYTOCHLORIN; PORPHYRIN;

ANIMAL; MICELLE; MOUSE; PHOTOCHEMOTHERAPY; POSITRON EMISSION TOMOGRAPHY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; MICE; MICELLES; NANOPARTICLES; PHOTOCHEMOTHERAPY; PORPHYRINS; POSITRON-EMISSION TOMOGRAPHY;

EID: 84983392671     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b03074     Document Type: Article

References (52)

1. Bardhan, R.; Lal, S.; Joshi, A.; Halas, N. J. Theranostic Nanoshells: From Probe Design to Imaging and Treatment of Cancer Acc. Chem. Res. 2011, 44, 936-946 10.1021/ar200023x
2. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(03)13038-3/abstract.
3. Paltauf, G.; Dyer, P. E. Photomechanical Processes and Effects in Ablation Chem. Rev. 2003, 103, 487-518 10.1021/cr010436c
4. Cheng, L.; Wang, C.; Feng, L.; Yang, K.; Liu, Z. Functional Nanomaterials for Phototherapies of Cancer Chem. Rev. 2014, 114, 10869-10939 10.1021/cr400532z
5. Dolmans, D. E. J. G. J.; Fukumura, D.; Jain, R. K. Photodynamic Therapy for Cancer Nat. Rev. Cancer 2003, 3, 380-387 10.1038/nrc1071
6. Moore, C. M.; Pendse, D.; Emberton, M. Photodynamic Therapy for Prostate Cancer: A Review of Current Status and Future Promise Nat. Clin. Pract. Urol. 2009, 6, 18-30 10.1038/ncpuro1274
7. Kamkaew, A.; Lim, S. H.; Lee, H. B.; Kiew, L. V.; Chung, L. Y.; Burgess, K. BODIPY Dyes in Photodynamic Therapy Chem. Soc. Rev. 2013, 42, 77-88 10.1039/C2CS35216H
8. Zhen, Z.; Tang, W.; Chuang, Y.-J.; Todd, T.; Zhang, W.; Lin, X.; Niu, G.; Liu, G.; Wang, L.; Pan, Z.; Chen, X.; Xie, J. Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles ACS Nano 2014, 8, 6004-6013 10.1021/nn501134q
9. Celli, J. P.; Spring, B. Q.; Rizvi, I.; Evans, C. L.; Samkoe, K. S.; Verma, S.; Pogue, B. W.; Hasan, T. Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization Chem. Rev. 2010, 110, 2795-2838 10.1021/cr900300p
10. Ethirajan, M.; Chen, Y.; Joshi, P.; Pandey, R. K. The Role of Porphyrin Chemistry in Tumor Imaging and Photodynamic Therapy Chem. Soc. Rev. 2011, 40, 340-362 10.1039/B915149B
11. Hamblin, M. R.; Miller, J. L.; Rizvi, I.; Ortel, B.; Maytin, E. V.; Hasan, T. Pegylation of a Chlorin e6 Polymer Conjugate Increases Tumor Targeting of Photosensitizer Cancer Res. 2001, 61, 7155-7162
12. Lammers, T.; Aime, S.; Hennink, W. E.; Storm, G.; Kiessling, F. Theranostic Nanomedicine Acc. Chem. Res. 2011, 44, 1029-1038 10.1021/ar200019c
13. Barnett, B. P.; Arepally, A.; Karmarkar, P. V.; Qian, D.; Gilson, W. D.; Walczak, P.; Howland, V.; Lawler, L.; Lauzon, C.; Stuber, M.; Kraitchman, D. L.; Bulte, J. W. M. Magnetic Resonance-Guided, Real-time Targeted Delivery and Imaging of Magnetocapsules Immunoprotecting Pancreatic Islet Cells Nat. Med. 2007, 13, 986-991 10.1038/nm1581
14. Shen, J.; Zhao, L.; Han, G. Lanthanide-doped Upconverting Luminescent Nanoparticle Platforms for Optical Imaging-Guided Drug Delivery and Therapy Adv. Drug Delivery Rev. 2013, 65, 744-755 10.1016/j.addr.2012.05.007
15. de Jong, M.; Essers, J.; van Weerden, W. M. Imaging Preclinical Tumour Models: Improving Translational Power Nat. Rev. Cancer 2014, 14, 481-493 10.1038/nrc3751
16. Cheng, Y.; Meyers, J. D.; Broome, A.-M.; Kenney, M. E.; Basilion, J. P.; Burda, C. Deep Penetration of a PDT Drug into Tumors by Noncovalent Drug-Gold Nanoparticle Conjugates J. Am. Chem. Soc. 2011, 133, 2583-2591 10.1021/ja108846h
17. Lin, J.; Wang, S.; Huang, P.; Wang, Z.; Chen, S.; Niu, G.; Li, W.; He, J.; Cui, D.; Lu, G.; Chen, X.; Nie, Z. Photosensitizer-Loaded Gold Vesicles with Strong Plasmonic Coupling Effect for Imaging-Guided Photothermal/Photodynamic Therapy ACS Nano 2013, 7, 5320-5329 10.1021/nn4011686
18. Zhang, Y.; Qian, J.; Wang, D.; Wang, Y.; He, S. Multifunctional Gold Nanorods with Ultrahigh Stability and Tunability for In Vivo Fluorescence Imaging, SERS Detection, and Photodynamic Therapy Angew. Chem., Int. Ed. 2013, 52, 1148-1151 10.1002/anie.201207909
19. Tian, B.; Wang, C.; Zhang, S.; Feng, L.; Liu, Z. Photothermally Enhanced Photodynamic Therapy Delivered by Nano-Graphene Oxide ACS Nano 2011, 5, 7000-7009 10.1021/nn201560b
20. Huang, P.; Lin, J.; Wang, X.; Wang, Z.; Zhang, C.; He, M.; Wang, K.; Chen, F.; Li, Z.; Shen, G.; Cui, D.; Chen, X. Light-Triggered Theranostics Based on Photosensitizer-Conjugated Carbon Dots for Simultaneous Enhanced-Fluorescence Imaging and Photodynamic Therapy Adv. Mater. 2012, 24, 5104-5110 10.1002/adma.201200650
21. Ge, J.; Lan, M.; Zhou, B.; Liu, W.; Guo, L.; Wang, H.; Jia, Q.; Niu, G.; Huang, X.; Zhou, H.; Meng, X.; Wang, P.; Lee, C.-S.; Zhang, W.; Han, X. A Graphene Quantum Dot Photodynamic Therapy Agent with High Singlet Oygen Generation Nat. Commun. 2014, 5, 4596 10.1038/ncomms5596
22. Coll, C.; Bernardos, A.; Martínez-Máñez, R.; Sancenón, F. Gated Silica Mesoporous Supports for Controlled Release and Signaling Applications Acc. Chem. Res. 2013, 46, 339-349 10.1021/ar3001469
23. Zhang, C.; Zhao, K.; Bu, W.; Ni, D.; Liu, Y.; Feng, J.; Shi, J. Marriage of Scintillator and Semiconductor for Synchronous Radiotherapy and Deep Photodynamic Therapy with Diminished Oxygen Dependence Angew. Chem. 2015, 127, 1790-1794 10.1002/ange.201408472
24. Idris, N. M.; Gnanasammandhan, M. K.; Zhang, J.; Ho, P. C.; Mahendran, R.; Zhang, Y. In Vivo Photodynamic Therapy Using Upconversion Nanoparticles as Remote-Controlled Nanotransducers Nat. Med. 2012, 18, 1580-1585 10.1038/nm.2933
25. Wang, C.; Tao, H.; Cheng, L.; Liu, Z. Near-Infrared Light Induced In Vivo Photodynamic Therapy of Cancer based on Upconversion Nanoparticles Biomaterials 2011, 32, 6145-6154 10.1016/j.biomaterials.2011.05.007
26. Nomoto, T.; Fukushima, S.; Kumagai, M.; Machitani, K.; Arnida; Matsumoto, Y.; Oba, M.; Miyata, K.; Osada, K.; Nishiyama, N.; Kataoka, K. Three-Layered Polyplex Micelle as A Multifunctional Nanocarrier Platform for Light-Induced Systemic Gene Transfer Nat. Commun. 2014, 5, 3545 10.1038/ncomms4545
27. Van Nostrum, C. F. Polymeric Micelles to Deliver Photosensitizers for Photodynamic Therapy Adv. Drug Delivery Rev. 2004, 56, 9-16 10.1016/j.addr.2003.07.013
28. Elsabahy, M.; Heo, G. S.; Lim, S.-M.; Sun, G.; Wooley, K. L. Polymeric Nanostructures for Imaging and Therapy Chem. Rev. 2015, 115, 10967-11011 10.1021/acs.chemrev.5b00135
29. Huang, Y.-Y.; Sharma, S. K.; Dai, T.; Chung, H.; Yaroslavsky, A.; Garcia-Diaz, M.; Chang, J.; Chiang, L. Y.; Hamblin, M. R. Can Nanotechnology Potentiate Photodynamic Therapy? Nanotechnol. Rev. 2012, 1, 111-146 10.1515/ntrev-2011-0005
30. Sheng, Z.; Hu, D.; Zheng, M.; Zhao, P.; Liu, H.; Gao, D.; Gong, P.; Gao, G.; Zhang, P.; Ma, Y.; Cai, L. Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy ACS Nano 2014, 8, 12310-12322 10.1021/nn5062386
31. Kim, C. S.; Tonga, G. Y.; Solfiell, D.; Rotello, V. M. Inorganic Nanosystems for Therapeutic Delivery: Status and Prospects Adv. Drug Delivery Rev. 2013, 65, 93-99 10.1016/j.addr.2012.08.011
32. Yang, Z.-Y.; Li, H.; Zeng, Y.-P.; Hao, Y.-H.; Liu, C.; Liu, J.; Wang, W.-D.; Li, R. Photosensitizer-Loaded Branched Polyethylenimine-PEGylated Ceria Nanoparticles for Imaging-Guided Synchronous Photochemotherapy ACS Appl. Mater. Interfaces 2015, 7, 24218-24228 10.1021/acsami.5b07702
33. Peer, D.; Karp, J. M.; Hong, S.; Farokhzad, O. C.; Margalit, R.; Langer, R. Nanocarriers as An Emerging Platform for Cancer Therapy Nat. Nanotechnol. 2007, 2, 751-760 10.1038/nnano.2007.387
34. Brigger, I.; Dubernet, C.; Couvreur, P. Nanoparticles in Cancer Therapy and Diagnosis Adv. Drug Delivery Rev. 2012, 64, 24-36 10.1016/j.addr.2012.09.006
35. Li, Y.; Lin, T.-y.; Luo, Y.; Liu, Q.; Xiao, W.; Guo, W.; Lac, D.; Zhang, H.; Feng, C.; Wachsmann-Hogiu, S.; Walton, J. H.; Cherry, S. R.; Rowland, D. J.; Kukis, D.; Pan, C.; Lam, K. S. A Smart and Versatile Theranostic Nanomedicine Platform based on Nanoporphyrin Nat. Commun. 2014, 5, 4712 10.1038/ncomms5712
36. Lovell, J. F.; Jin, C. S.; Huynh, E.; Jin, H.; Kim, C.; Rubinstein, J. L.; Chan, W. C. W.; Cao, W.; Wang, L. V.; Zheng, G. Porphysome Nanovesicles Generated by Porphyrin Bilayers for Use as Multimodal Biophotonic Contrast Agents Nat. Mater. 2011, 10, 324-332 10.1038/nmat2986
37. Lovell, J. F.; Liu, T. W. B.; Chen, J.; Zheng, G. Activatable Photosensitizers for Imaging and Therapy Chem. Rev. 2010, 110, 2839-2857 10.1021/cr900236h
38. Gong, H.; Dong, Z.; Liu, Y.; Yin, S.; Cheng, L.; Xi, W.; Xiang, J.; Liu, K.; Li, Y.; Liu, Z. Engineering of Multifunctional Nano-Micelles for Combined Photothermal and Photodynamic Therapy Under the Guidance of Multimodal Imaging Adv. Funct. Mater. 2014, 24, 6492-6502 10.1002/adfm.201401451
39. Chen, Q.; Wang, X.; Wang, C.; Feng, L.; Li, Y.; Liu, Z. Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy ACS Nano 2015, 9, 5223-5233 10.1021/acsnano.5b00640
40. Hou, W.; Xia, F.; Alves, C. S.; Qian, X.; Yang, Y.; Cui, D. MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy ACS Appl. Mater. Interfaces 2016, 8, 1447-1457 10.1021/acsami.5b10772
41. Sun, X.; Cai, W.; Chen, X. Positron Emission Tomography Imaging Using Radiolabeled Inorganic Nanomaterials Acc. Chem. Res. 2015, 48, 286-294 10.1021/ar500362y
42. 64Cu-Doped CdSe/ZnS Nanocrystals for In Vivo Tumor Imaging J. Am. Chem. Soc. 2014, 136, 1706-1709 10.1021/ja410438n
43. Cheng, L.; He, W.; Gong, H.; Wang, C.; Chen, Q.; Cheng, Z.; Liu, Z. PEGylated Micelle Nanoparticles Encapsulating A Non-Fluorescent Near-Infrared Organic Dye as A Safe and Highly-Effective Photothermal Agent for In Vivo Cancer Therapy Adv. Funct. Mater. 2013, 23, 5893-5902 10.1002/adfm.201301045
44. Xia, X.; Yang, M.; Wang, Y.; Zheng, Y.; Li, Q.; Chen, J.; Xia, Y. Quantifying the Coverage Density of Poly(ethylene glycol) Chains on the Surface of Gold Nanostructures ACS Nano 2012, 6, 512-522 10.1021/nn2038516
45. Kunjachan, S.; Pola, R.; Gremse, F.; Theek, B.; Ehling, J.; Moeckel, D.; Hermanns-Sachweh, B.; Pechar, M.; Ulbrich, K.; Hennink, W. E.; Storm, G.; Lederle, W.; Kiessling, F.; Lammers, T. Passive versus Active Tumor Targeting Using RGD- and NGR-Modified Polymeric Nanomedicines Nano Lett. 2014, 14, 972-981 10.1021/nl404391r
46. Guo, J.; Hong, H.; Chen, G.; Shi, S.; Zheng, Q.; Zhang, Y.; Theuer, C. P.; Barnhart, T. E.; Cai, W.; Gong, S. Image-Guided and Tumor-Targeted Drug Delivery with Radiolabeled Unimolecular Micelles Biomaterials 2013, 34, 8323-8332 10.1016/j.biomaterials.2013.07.085
47. Rieffel, J.; Chitgupi, U.; Lovell, J. F. Recent Advances in Higher-Order, Multimodal, Biomedical Imaging Agents Small 2015, 11, 4445-4461 10.1002/smll.201500735
48. Lee, D.-E.; Koo, H.; Sun, I.-C.; Ryu, J. H.; Kim, K.; Kwon, I. C. Multifunctional Nanoparticles for Multimodal Imaging and Theragnosis Chem. Soc. Rev. 2012, 41, 2656-2672 10.1039/C2CS15261D
49. Kim, J.; Piao, Y.; Hyeon, T. Multifunctional Nanostructured Materials for Multimodal Imaging, and Simultaneous Imaging and Therapy Chem. Soc. Rev. 2009, 38, 372-390 10.1039/B709883A
50. Evangelista, L.; Zattoni, F.; Guttilla, A.; Saladini, G.; Zattoni, F.; Colletti, P. M.; Rubello, D. Choline PET or PET/CT and Biochemical Relapse of Prostate Cancer: A Systematic Review and Meta-Analysis Clin. Nucl. Med. 2013, 38, 305-314 10.1097/RLU.0b013e3182867f3c
51. Yang, G.; Gong, H.; Qian, X.; Tan, P.; Li, Z.; Liu, T.; Liu, J.; Li, Y.; Liu, Z. Mesoporous Silica Nanorods Intrinsically Doped with Photosensitizers as A Multifunctional Drug Carrier for Combination Therapy of Cancer Nano Res. 2015, 8, 751-764 10.1007/s12274-014-0558-0
52. 64Cu-Labeling and Multimodal Image-Guided Photothermal-Radiation Therapy Adv. Funct. Mater. 2016, 26, 2185-2197 10.1002/adfm.201504810