Investigation on fabrication process of dissolving microneedle arrays to improve effective needle drug distribution

European Journal of Pharmaceutical Sciences

Volumn 66, Issue , 2015, Pages 148-156

  Wang, Qingqing ^a,b   Yao, Gangtao ^a   Dong, Pin ^a   Gong, Zihua ^a   Li, Ge ^c   Zhang, Kejian ^a   Wu, Chuanbin ^a,d  

^a SUN YAT SEN UNIVERSITY   (China)

^b BENGBU MEDICAL COLLEGE   (China)

^c Guangzhou Neworld Pharm Co Ltd   (China)

^d Guangdong Research Center for Drug Delivery Systems   (China)

Author keywords

Dissolving microneedle array (DMNA); Drug diffusion; Drug distribution; Solvent evaporation; Transdermal drug delivery; Two step molding

Indexed keywords

ALCOHOL; METOPROLOL TARTRATE; WATER; ANTIARRHYTHMIC AGENT; BIOMATERIAL; BOVINE SERUM ALBUMIN; METOPROLOL;

ANALYTICAL PARAMETERS; ANIMAL TISSUE; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DISSOLVING MICRONEEDLE ARRAY; DRUG CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG STORAGE; EVAPORATION; IN VITRO STUDY; MICRONEEDLE; NANOFABRICATION; NEEDLE DRUG LOADING PROPORTION; NONHUMAN; PIG; PRIORITY JOURNAL; TRANSDERMAL DRUG DELIVERY SYSTEM; VISCOSITY; ANIMAL; CHEMISTRY; DRUG RELEASE; EQUIPMENT DESIGN; NEEDLE; TIME FACTOR;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; BIOCOMPATIBLE MATERIALS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG STORAGE; EQUIPMENT DESIGN; METOPROLOL; NEEDLES; SERUM ALBUMIN, BOVINE; TIME FACTORS;

EID: 84983374317     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.09.011     Document Type: Article

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