Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase

International Journal of Neuropsychopharmacology

Volumn 18, Issue 3, 2015, Pages

  Nava, Nicoletta ^a,b   Treccani, Giulia ^b,d   Liebenberg, Nico ^b   Chen, Fenghua ^a,b   Popoli, Maurizio ^d   Wegener, Gregers ^b,c   Nyengaard, Jens Randel ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c NORTH WEST UNIVERSITY   (South Africa)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Desipramine; Glutamate; Stress; Synapse

Indexed keywords

CORTICOSTERONE; DESIPRAMINE; GLUTAMIC ACID; TRICYCLIC ANTIDEPRESSANT AGENT; VESICULAR GLUTAMATE TRANSPORTER 1;

ACUTE STRESS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EXCITATORY POSTSYNAPTIC POTENTIAL; FOOTSHOCK; MALE; MEDIAL PREFRONTAL CORTEX; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; RAT; SYNAPSE; ANIMAL; BIOLOGICAL MODEL; BLOOD; DISEASE MODEL; DRUG EFFECTS; ELECTROSHOCK; ETIOLOGY; MENTAL STRESS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; PREVENTION AND CONTROL; SPRAGUE DAWLEY RAT; SYNAPSE VESICLE; TIME FACTOR; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CORTICOSTERONE; DESIPRAMINE; DISEASE MODELS, ANIMAL; ELECTROSHOCK; GLUTAMIC ACID; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, NEUROLOGICAL; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; SYNAPSES; SYNAPTIC VESICLES; TIME FACTORS; VESICULAR GLUTAMATE TRANSPORT PROTEIN 1;

EID: 84983330019     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu085     Document Type: Article

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