Clinical significance of circulating vascular cell adhesion molecule-1 to white matter disintegrity in Alzheimer’s dementia

Thrombosis and Haemostasis

Volumn 114, Issue 6, 2015, Pages 1230-1240

  Huang, Chi Wei ^a   Tsai, Meng Han ^a   Chen, Nai Ching ^a   Chen, Wei Hsi ^a   Lu, Yan Ting ^a   Lui, Chun Chung ^a   Chang, Ya Ting ^a   Chang, Wen Neng ^a   Chang, Alice Y W ^b   Chang, Chiung Chih ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Alzheimer s dementia; Cell adhesion molecule 1; Magnetic resonance imaging; White matter disease

Indexed keywords

APOLIPOPROTEIN E; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; VASCULAR CELL ADHESION MOLECULE 1; APOLIPOPROTEIN E4; SELE PROTEIN, HUMAN;

AGED; ALZHEIMER DISEASE; ARTICLE; COGNITION ASSESSMENT; CONTROLLED STUDY; CORPUS CALLOSUM; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCORING SYSTEM; SHORT TERM MEMORY; STRIA TERMINALIS; SUPERIOR LONGITUDINAL FASCICULUS; THALAMUS POSTERIOR NUCLEUS; BLOOD; CASE CONTROL STUDY; CEREBROVASCULAR DISORDERS; COMORBIDITY; COMPARATIVE STUDY; DIABETES MELLITUS; DIFFUSION TENSOR IMAGING; DYSLIPIDEMIAS; GENETICS; HYPERTENSION; PATHOLOGY; PATHOPHYSIOLOGY; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SMOKING; VASCULAR ENDOTHELIUM; VERY ELDERLY; WHITE MATTER;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; CASE-CONTROL STUDIES; CEREBROVASCULAR DISORDERS; COMORBIDITY; DIABETES MELLITUS; DIFFUSION TENSOR IMAGING; DYSLIPIDEMIAS; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPERTENSION; INTERCELLULAR ADHESION MOLECULE-1; MAGNETIC RESONANCE IMAGING; MALE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SMOKING; VASCULAR CELL ADHESION MOLECULE-1; WHITE MATTER;

EID: 84983200495     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH14-11-0938     Document Type: Article

References (60)

1. Ott A, Breteler MM, van Harskamp F, et al. Prevalence of Alzheimer’s disease and vascular dementia: association with education. The Rotterdam study. Br Med J 1995; 310: 970-973.
2. Cullen KM, Kocsi Z, Stone J. Microvascular pathology in the aging human brain: evidence that senile plaques are sites of microhaemorrhages. Neurobiol Aging 2006; 27: 1786-1796.
3. Huang CW, Chang WN, Lui CC, et al. Impacts of hyper-homocysteinemia and white matter hyper-intensity in Alzheimer’s disease patients with normal creatinine: an MRI-based study with longitudinal follow-up. CurrAlzheimer Res 2010; 7: 527-533.
4. Bailey TL, Rivara CB, Rocher AB, et al. The nature and effects of cortical microvascular pathology in aging and Alzheimer’s disease. Neurol Res 2004; 26: 573-578.
5. Breteler MM. Vascular involvement in cognitive decline and dementia. Epidemiologic evidence from the Rotterdam Study and the Rotterdam Scan Study. Ann NY Acad Sci 2000; 903: 457-465.
6. de la Torre JC. Is Alzheimer’s disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics. Lancet Neurol 2004; 3: 184-190.
7. Tu MC, Huang CW, Chen NC, et al. Hyperhomocysteinemia in Alzheimer dementia patients and cognitive decline after 6 months follow-up period. Acta Neurol Taiwan 2010; 19: 168-177.
8. Chang YT, Chang CC, Lin HS, et al. Montreal cognitive assessment in assessing clinical severity and white matter hyperintensity in Alzheimer’s disease with normal control comparison. Acta Neurol Taiwan 2012; 21: 64-73.
9. Deppe M, Duning T, Mohammadi S, et al. Diffusion-tensor imaging at 3 T: detection of white matter alterations in neurological patients on the basis of normal values. Invest Radiol 2007; 42: 338-345.
10. Hoth KF, Haley AP, Gunstad J, et al. Elevated C-reactive protein is related to cognitive decline in older adults with cardiovascular disease. J Am Geriatr Soc 2008; 56: 1898-1903.
11. Wright CB, Sacco RL, Rundek T, et al. Interleukin-6 is associated with cognitive function: the Northern Manhattan Study. J Stroke Cerebrovasc Dis 2006; 15: 34-38.
12. Huang CW, Chang WN, Huang SH, et al. Impact of homocysteine on cortical perfusion and cognitive decline in mild Alzheimer’s dementia. Eur J Neurol 2013; 20: 1191-1197.
13. Carlos TM, Harlan JM. Leukocyte-endothelial adhesion molecules. Blood 1994; 84: 2068-2101.
14. Deanfield JE, Halcox JP, Rabelink TJ. Endothelial function and dysfunction: testing and clinical relevance. Circulation 2007; 115: 1285-1295.
15. Hassan A, Hunt BJ, O’Sullivan M, et al. Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis. Brain 2003; 126: 424-432.
16. Markus HS, Hunt B, Palmer K, et al. Markers of endothelial and hemostatic activation and progression of cerebral white matter hyperintensities: longitudinal results of the Austrian Stroke Prevention Study. Stroke 2005; 36: 1410-1414.
17. Galkina E, Ley K. Vascular adhesion molecules in atherosclerosis. Arterioscl Thromb Vasc Biol 2007; 27: 2292-2301.
18. Zuliani G, Cavalieri M, Galvani M, et al. Markers of endothelial dysfunction in older subjects with late onset Alzheimer’s disease or vascular dementia. J Neurol Sci 2008; 272: 164-170.
19. Rentzos M, Michalopoulou M, Nikolaou C, et al. Serum levels of soluble intercellular adhesion molecule-1 and soluble endothelial leukocyte adhesion molecule-1 in Alzheimer’s disease. J Geriatric Psych Neurol 2004; 17: 225-231.
20. Nielsen HM, Londos E, Minthon L, et al. Soluble adhesion molecules and angiotensin-converting enzyme in dementia. Neurobiol Dis 2007; 26: 27-35.
21. Schleimer RP, Sterbinsky SA, Kaiser J, et al. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol 1992; 148: 1086-1092.
22. Verbeek MM, Otte-Holler I, Westphal JR, et al. Accumulation of intercellular adhesion molecule-1 in senile plaques in brain tissue of patients with Alzheimer’s disease. Am J Pathol 1994; 144: 104-116.
23. Alexander AL, Lee JE, Lazar M, et al. Diffusion tensor imaging of the brain. Neurotherapeutics 2007; 4: 316-329.
24. Hua K, Zhang J, Wakana S, et al. Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification. Neuroimage 2008; 39: 336-347.
25. Fazekas F, Kapeller P, Schmidt R, et al. The relation of cerebral magnetic resonance signal hyperintensities to Alzheimer’s disease. J Neurol Sci 1996; 142: 121-125.
26. Morey RA, Petty CM, Xu Y, et al. A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes. NeuroImage 2009; 45: 855-866.
27. Sanchez-Madrid F, Gonzalez-Amaro R. Drugs, inflammation and cell adhesion receptors. Exp Opin Pharmacother 2001; 2: 3-17.
28. Rouhl RP, Damoiseaux JG, Lodder J, et al. Vascular inflammation in cerebral small vessel disease. Neurobiol Aging 2012; 33: 1800-1806.
29. Koedam EL, Lauffer V, van der Vlies AE, et al. Early-versus late-onset Alzheimer’s disease: more than age alone. J Alzheimer Dis 2010; 19: 1401-1408.
30. Chang CC, Chang YY, Chang WN, et al. Cognitive deficits in multiple system atrophy correlate with frontal atrophy and disease duration. Eur J Neurol 2009; 16: 1144-1150.
31. American psychiatric associations diagnostic and statistical manual of mental disorders, ed 4 (dsm-iv) american psychiatric association washington; 1994.
32. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 1984; 34: 939-944.
33. Chang YT, Huang CW, Chang YH, et al. Amyloid burden in the hippocampus and default mode network: relationships with gray matter volume and cognitive performance in mild stage Alzheimer disease. Medicine 2015; 94: e763.
34. McMurray RW. Adhesion molecules in autoimmune disease. Semin Arthritis Rheuma 1996; 25: 215-233.
35. Weitz-Schmidt G. Statins as anti-inflammatory agents. Trends Pharmacol Sci 2002; 23: 482-486.
36. Gavin JR, 3rd. New classification and diagnostic criteria for diabetes mellitus. Clin Cornerstone 1998; 1: 1-12.
37. Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. J Am Med Assoc 2003; 289: 2560-2572.
38. Folstein MF, Folstein SE, McHugh PR. „Mini-mental state“. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
39. Teng EL, Hasegawa K, Homma A, et al. The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr 1994; 6: 45-58; discussion 62.
40. Del Bo R, Comi GP, Bresolin N, et al. The apolipoprotein E epsilon4 allele causes a faster decline of cognitive performances in Down’s syndrome subjects. J Neurol Sci 1997; 145: 87-91.
41. de Leeuw FE, de Kleine M, Frijns CJ, et al. Endothelial cell activation is associated with cerebral white matter lesions in patients with cerebrovascular disease. Ann NY Acad Sci 2002; 977: 306-314.
42. de la Torre JC. Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer’s pathogenesis. Neurobiol Aging 2000; 21: 331-342.
43. Borroni B, Volpi R, Martini G, et al. Peripheral blood abnormalities in Alzheimer disease: evidence for early endothelial dysfunction. Alzheimer Dis Assoc Disorders 2002; 16: 150-155.
44. Bilato C, Crow MT. Atherosclerosis and the vascular biology of aging. Aging 1996; 8: 221-234.
45. Merat S, Fruebis J, Sutphin M, et al. Effect of aging on aortic expression of the vascular cell adhesion molecule-1 and atherosclerosis in murine models of atherosclerosis. J Gerontol A Biol Sci Med Sci 2000; 55: B85-94.
46. Hassan A, Hunt BJ, O’Sullivan M, et al. Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Brain 2004; 127: 212-219.
47. Varela-Moreiras G, Murphy MM, Scott JM. Cobalamin, folic acid, and homocysteine. Nutr Rev 2009; 67 (Suppl 1): S69-72.
48. Baro L, Fonolla J, Pena JL, et al. n-3 Fatty acids plus oleic acid and vitamin supplemented milk consumption reduces total and LDL cholesterol, homocysteine and levels of endothelial adhesion molecules in healthy humans. Clin Nutr 2003; 22: 175-182.
49. Marz W, Scharnagl H, Winkler K, et al. Low-density lipoprotein triglycerides associated with low-grade systemic inflammation, adhesion molecules, and angiographic coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health study. Circulation 2004; 110: 3068-3074.
50. Jellinger KA. Alzheimer disease and cerebrovascular pathology: an update. J Neural Transm 2002; 109: 813-836.
51. Garg N, Krishan P, Syngle A. Rosuvastatin improves endothelial dysfunction in ankylosing spondylitis. Clin Rheumatol 2015; 34: 1065-1071.
52. Pierpaoli C, Barnett A, Pajevic S, et al. Water diffusion changes in Wallerian degeneration and their dependence on white matter architecture. NeuroImage 2001; 13: 1174-1185.
53. Radanovic M, Pereira FR, Stella F, et al. White matter abnormalities associated with Alzheimer’s disease and mild cognitive impairment: a critical review of MRI studies. Exp Rev Neurotherap 2013; 13: 483-493.
54. Vestergaard M, Madsen KS, Baare WF, et al. White matter microstructure in superior longitudinal fasciculus associated with spatial working memory performance in children. J Cogn Neurosci 2011; 23: 2135-2146.
55. Stebbins GT, Murphy CM. Diffusion tensor imaging in Alzheimer’s disease and mild cognitive impairment. Behav Neurol 2009; 21: 39-49.
56. Forsberg A, Engler H, Almkvist O, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging 2008; 29: 1456-1465.
57. Hwang SJ, Ballantyne CM, Sharrett AR, et al. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation 1997; 96: 4219-4225.
58. Mielke MM, Zandi PP, Sjogren M, et al. High total cholesterol levels in late life associated with a reduced risk of dementia. Neurology 2005; 64: 1689-1695.
59. Kivipelto M, Helkala EL, Laakso MP, et al. Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med 2002; 137: 149-155.
60. Fassbender K, Bertsch T, Mielke O, et al. Adhesion molecules in cerebrovascular diseases. Evidence for an inflammatory endothelial activation in cerebral largeand small-vessel disease. Stroke 1999; 30: 1647-1650.