-
1
-
-
0141672946
-
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
-
Rosenwald A, Wright G, Leroy K, et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 2003;198:851–862.
-
(2003)
J Exp Med
, vol.198
, pp. 851-862
-
-
Rosenwald, A.1
Wright, G.2
Leroy, K.3
-
2
-
-
10744228934
-
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma
-
Savage KJ, Monti S, Kutok JL, et al. The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. Blood 2003;102:3871–3879.
-
(2003)
Blood
, vol.102
, pp. 3871-3879
-
-
Savage, K.J.1
Monti, S.2
Kutok, J.L.3
-
3
-
-
84920574046
-
Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: Do they require a unique therapeutic approach?
-
Dunleavy K, Wilson WH. Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: Do they require a unique therapeutic approach? Blood 2015;125:33–39.
-
(2015)
Blood
, vol.125
, pp. 33-39
-
-
Dunleavy, K.1
Wilson, W.H.2
-
4
-
-
80052673612
-
The molecular pathogenesis of primary mediastinal large B-cell lymphoma
-
Steidl C, Gascoyne RD. The molecular pathogenesis of primary mediastinal large B-cell lymphoma. Blood 2011;118:2659–2669.
-
(2011)
Blood
, vol.118
, pp. 2659-2669
-
-
Steidl, C.1
Gascoyne, R.D.2
-
5
-
-
84898058507
-
Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma
-
Gunawardana J, Chan FC, Telenius A, et al. Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma. Nat Genet 2014;46:329–335.
-
(2014)
Nat Genet
, vol.46
, pp. 329-335
-
-
Gunawardana, J.1
Chan, F.C.2
Telenius, A.3
-
6
-
-
84917729620
-
Activating mutations affecting the NF-kappa B pathway and EZH2-mediated epigenetic regulation are rare events in primary mediastinal large B-cell lymphoma
-
Gebauer N, Hardel TT, Gebauer J, et al. Activating mutations affecting the NF-kappa B pathway and EZH2-mediated epigenetic regulation are rare events in primary mediastinal large B-cell lymphoma. Anticancer Res 2014;34:5503–5507.
-
(2014)
Anticancer Res
, vol.34
, pp. 5503-5507
-
-
Gebauer, N.1
Hardel, T.T.2
Gebauer, J.3
-
7
-
-
84960280978
-
Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma
-
in press
-
Mareschal S, Dubois S, Viailly P, et al. Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma. Genes Chromosomes Cancer, in press.
-
Genes Chromosomes Cancer
-
-
Mareschal, S.1
Dubois, S.2
Viailly, P.3
-
8
-
-
84975086212
-
Next generation sequencing in diffuse large B cell lymphoma highlights molecular divergence and therapeutic opportunities: A LYSA study
-
Dubois S, Viailly PJ, Mareschal S, et al. Next generation sequencing in diffuse large B cell lymphoma highlights molecular divergence and therapeutic opportunities: A LYSA study. Clin Cancer Res 2016;22:2919–2928.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 2919-2928
-
-
Dubois, S.1
Viailly, P.J.2
Mareschal, S.3
-
9
-
-
84891866590
-
SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients
-
Jeromin S, Weissmann S, Haferlach C, et al. SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients. Leukemia 2014;28:108–117.
-
(2014)
Leukemia
, vol.28
, pp. 108-117
-
-
Jeromin, S.1
Weissmann, S.2
Haferlach, C.3
-
10
-
-
84899628626
-
Genomic and molecular characterization of esophageal squamous cell carcinoma
-
Lin DC, Hao JJ, Nagata Y, et al. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet 2014;46:467–473.
-
(2014)
Nat Genet
, vol.46
, pp. 467-473
-
-
Lin, D.C.1
Hao, J.J.2
Nagata, Y.3
-
11
-
-
84909592602
-
Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL
-
Bond J, Bergon A, Durand A, et al. Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL. Blood 2014;124:3023–3025.
-
(2014)
Blood
, vol.124
, pp. 3023-3025
-
-
Bond, J.1
Bergon, A.2
Durand, A.3
-
12
-
-
84875052270
-
KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia
-
Etchin J, Sanda T, Mansour MR, et al. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. Br J Haematol 2013;161:117–127.
-
(2013)
Br J Haematol
, vol.161
, pp. 117-127
-
-
Etchin, J.1
Sanda, T.2
Mansour, M.R.3
-
13
-
-
84870502798
-
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
-
Lapalombella R, Sun Q, Williams K, et al. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood 2012;120:4621–4634.
-
(2012)
Blood
, vol.120
, pp. 4621-4634
-
-
Lapalombella, R.1
Sun, Q.2
Williams, K.3
-
14
-
-
79955473473
-
Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: A multicentre, single-arm, phase 2 trial
-
Peyrade F, Jardin F, Thieblemont C, et al. Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: A multicentre, single-arm, phase 2 trial. Lancet Oncol 2011;12:460–468.
-
(2011)
Lancet Oncol
, vol.12
, pp. 460-468
-
-
Peyrade, F.1
Jardin, F.2
Thieblemont, C.3
-
15
-
-
82255186682
-
Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): An open-label randomised phase 3 trial
-
Recher C, Coiffier B, Haioun C, et al. Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): An open-label randomised phase 3 trial. Lancet 2011;378:1858–1867.
-
(2011)
Lancet
, vol.378
, pp. 1858-1867
-
-
Recher, C.1
Coiffier, B.2
Haioun, C.3
-
16
-
-
84876987456
-
Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): A randomised phase 3 trial
-
Delarue R, Tilly H, Mounier N, et al. Dose-dense rituximab-CHOP compared with standard rituximab-CHOP in elderly patients with diffuse large B-cell lymphoma (the LNH03-6B study): A randomised phase 3 trial. Lancet Oncol 2013;14:525–533.
-
(2013)
Lancet Oncol
, vol.14
, pp. 525-533
-
-
Delarue, R.1
Tilly, H.2
Mounier, N.3
-
17
-
-
79961096440
-
Survival impact of rituximab combined with ACVBP and upfront consolidation autotransplantation in high-risk diffuse large B-cell lymphoma for GELA
-
Fitoussi O, Belhadj K, Mounier N, et al. Survival impact of rituximab combined with ACVBP and upfront consolidation autotransplantation in high-risk diffuse large B-cell lymphoma for GELA. Haematologica 2011;96:1136–1143.
-
(2011)
Haematologica
, vol.96
, pp. 1136-1143
-
-
Fitoussi, O.1
Belhadj, K.2
Mounier, N.3
-
18
-
-
84875626098
-
Phase III study of ACVBP versus ACVBP plus rituximab for patients with localized low-risk diffuse large B-cell lymphoma (LNH03-1B)
-
Ketterer N, Coiffier B, Thieblemont C, et al. Phase III study of ACVBP versus ACVBP plus rituximab for patients with localized low-risk diffuse large B-cell lymphoma (LNH03-1B). Ann Oncol Off J Eur Soc Med Oncol ESMO 2013;24:1032–1037.
-
(2013)
Ann Oncol Off J Eur Soc Med Oncol ESMO
, vol.24
, pp. 1032-1037
-
-
Ketterer, N.1
Coiffier, B.2
Thieblemont, C.3
-
19
-
-
27244446911
-
Mediastinal gray zone lymphoma: The missing link between classic Hodgkin's lymphoma and mediastinal large B-cell lymphoma
-
Traverse-Glehen A, Pittaluga S, Gaulard P, et al. Mediastinal gray zone lymphoma: The missing link between classic Hodgkin's lymphoma and mediastinal large B-cell lymphoma. Am J Surg Pathol 2005;29:1411–1421.
-
(2005)
Am J Surg Pathol
, vol.29
, pp. 1411-1421
-
-
Traverse-Glehen, A.1
Pittaluga, S.2
Gaulard, P.3
-
20
-
-
0035342498
-
MedB-1, a human tumor cell line derived from a primary mediastinal large B-cell lymphoma
-
Moller P, Bruderlein S, Strater J, et al. MedB-1, a human tumor cell line derived from a primary mediastinal large B-cell lymphoma. Int J Cancer J Int Cancer 2001;92:348–353.
-
(2001)
Int J Cancer J Int Cancer
, vol.92
, pp. 348-353
-
-
Moller, P.1
Bruderlein, S.2
Strater, J.3
-
21
-
-
0027959643
-
B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression
-
Nacheva E, Dyer MJ, Metivier C, et al. B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression. Blood 1994;84:3422–3428.
-
(1994)
Blood
, vol.84
, pp. 3422-3428
-
-
Nacheva, E.1
Dyer, M.J.2
Metivier, C.3
-
22
-
-
30444435933
-
U-2940, a human B-cell line derived from a diffuse large cell lymphoma sequential to Hodgkin lymphoma
-
Sambade C, Berglund M, Lagercrantz S, et al. U-2940, a human B-cell line derived from a diffuse large cell lymphoma sequential to Hodgkin lymphoma. Int J Cancer J Int Cancer 2006;118:555–563.
-
(2006)
Int J Cancer J Int Cancer
, vol.118
, pp. 555-563
-
-
Sambade, C.1
Berglund, M.2
Lagercrantz, S.3
-
23
-
-
84958534910
-
Digital PCR for quantification of recurrent and potentially actionable somatic mutations in circulating free DNA from patients with diffuse large B-cell lymphoma
-
[Epub ahead of print] PMID 26883583
-
Camus V, Sarafan-Vasseur N, Bohers E, et al. Digital PCR for quantification of recurrent and potentially actionable somatic mutations in circulating free DNA from patients with diffuse large B-cell lymphoma. Leuk Lymph 2016;1–9. [Epub ahead of print] PMID: 26883583.
-
(2016)
Leuk Lymph
, pp. 1-9
-
-
Camus, V.1
Sarafan-Vasseur, N.2
Bohers, E.3
-
24
-
-
84904962600
-
Rgb: A scriptable genome browser for R
-
Mareschal S, Dubois S, Lecroq T, et al. Rgb: A scriptable genome browser for R. Bioinformatics 2014;30:2204–2205.
-
(2014)
Bioinformatics
, vol.30
, pp. 2204-2205
-
-
Mareschal, S.1
Dubois, S.2
Lecroq, T.3
-
25
-
-
83455219407
-
Jetset: Selecting the optimal microarray probe set to represent a gene
-
Li Q, Birkbak NJ, Gyorffy B, et al. Jetset: Selecting the optimal microarray probe set to represent a gene. BMC Bioinform 2011;12:474.
-
(2011)
BMC Bioinform
, vol.12
, pp. 474
-
-
Li, Q.1
Birkbak, N.J.2
Gyorffy, B.3
-
26
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie ME, Phipson B, Wu D, et al. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 2015;43:e47.
-
(2015)
Nucleic Acids Res
, vol.43
-
-
Ritchie, M.E.1
Phipson, B.2
Wu, D.3
-
27
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
Kau TR, Schroeder F, Ramaswamy S, et al. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell 2003;4:463–476.
-
(2003)
Cancer Cell
, vol.4
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
-
28
-
-
0042449063
-
Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group
-
Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group. J Clin Oncol Off J Am Soc Clin Oncol 1999;17:1244.
-
(1999)
J Clin Oncol Off J Am Soc Clin Oncol
, vol.17
, pp. 1244
-
-
Cheson, B.D.1
Horning, S.J.2
Coiffier, B.3
-
29
-
-
67349140506
-
Structural basis for leucine-rich nuclear export signal recognition by CRM1
-
Dong X, Biswas A, Suel KE, et al. Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature 2009;458:1136–1141.
-
(2009)
Nature
, vol.458
, pp. 1136-1141
-
-
Dong, X.1
Biswas, A.2
Suel, K.E.3
-
30
-
-
0036387236
-
Evaluation of structural and evolutionary contributions to deleterious mutation prediction
-
Saunders CT, Baker D. Evaluation of structural and evolutionary contributions to deleterious mutation prediction. J Mol Biol 2002;322:891–901.
-
(2002)
J Mol Biol
, vol.322
, pp. 891-901
-
-
Saunders, C.T.1
Baker, D.2
-
31
-
-
84895858942
-
A general framework for estimating the relative pathogenicity of human genetic variants
-
Kircher M, Witten DM, Jain P, et al. A general framework for estimating the relative pathogenicity of human genetic variants. Nat Genet 2014;46:310–315.
-
(2014)
Nat Genet
, vol.46
, pp. 310-315
-
-
Kircher, M.1
Witten, D.M.2
Jain, P.3
-
32
-
-
0030041048
-
Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene
-
Joos S, Otano-Joos MI, Ziegler S, et al. Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene. Blood 1996;87:1571–1578.
-
(1996)
Blood
, vol.87
, pp. 1571-1578
-
-
Joos, S.1
Otano-Joos, M.I.2
Ziegler, S.3
-
33
-
-
33947109366
-
Gains of REL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein
-
Weniger MA, Gesk S, Ehrlich S, et al. Gains of REL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein. Genes Chromosomes Cancer 2007;46:406–415.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 406-415
-
-
Weniger, M.A.1
Gesk, S.2
Ehrlich, S.3
-
34
-
-
51649111684
-
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
-
Lenz G, Wright GW, Emre NC, et al. Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci USA 2008;105:13520–13525.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13520-13525
-
-
Lenz, G.1
Wright, G.W.2
Emre, N.C.3
-
35
-
-
84923268725
-
Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells
-
Reichel J, Chadburn A, Rubinstein PG, et al. Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells. Blood 2015;125:1061–1072.
-
(2015)
Blood
, vol.125
, pp. 1061-1072
-
-
Reichel, J.1
Chadburn, A.2
Rubinstein, P.G.3
-
36
-
-
26644446700
-
B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity
-
Aguiar RC, Takeyama K, He C, et al. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. J Biol Chem 2005;280:33756–33765.
-
(2005)
J Biol Chem
, vol.280
, pp. 33756-33765
-
-
Aguiar, R.C.1
Takeyama, K.2
He, C.3
-
37
-
-
84920366106
-
CRM1 as a new therapeutic target for non-Hodgkin lymphoma
-
Han X, Wang J, Shen Y, et al. CRM1 as a new therapeutic target for non-Hodgkin lymphoma. Leuk Res 2015;39:38–46.
-
(2015)
Leuk Res
, vol.39
, pp. 38-46
-
-
Han, X.1
Wang, J.2
Shen, Y.3
-
38
-
-
84891847971
-
CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: Molecular mechanisms and therapeutic implications
-
Tai YT, Landesman Y, Acharya C, et al. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: Molecular mechanisms and therapeutic implications. Leukemia 2014;28:155–165.
-
(2014)
Leukemia
, vol.28
, pp. 155-165
-
-
Tai, Y.T.1
Landesman, Y.2
Acharya, C.3
-
39
-
-
33646382121
-
Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
-
Weniger MA, Melzner I, Menz CK, et al. Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation. Oncogene 2006;25:2679–2684.
-
(2006)
Oncogene
, vol.25
, pp. 2679-2684
-
-
Weniger, M.A.1
Melzner, I.2
Menz, C.K.3
-
40
-
-
69849087246
-
Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma
-
Ritz O, Guiter C, Castellano F, et al. Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma. Blood 2009;114:1236–1242.
-
(2009)
Blood
, vol.114
, pp. 1236-1242
-
-
Ritz, O.1
Guiter, C.2
Castellano, F.3
-
41
-
-
84865962469
-
Gray zone lymphoma: Better treated like Hodgkin lymphoma or mediastinal large B-cell lymphoma?
-
Dunleavy K, Grant C, Eberle FC, et al. Gray zone lymphoma: Better treated like Hodgkin lymphoma or mediastinal large B-cell lymphoma? Curr Hematol Malignancy Rep 2012;7:241–247.
-
(2012)
Curr Hematol Malignancy Rep
, vol.7
, pp. 241-247
-
-
Dunleavy, K.1
Grant, C.2
Eberle, F.C.3
-
42
-
-
23744486988
-
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes
-
Feuerhake F, Kutok JL, Monti S, et al. NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes. Blood 2005;106:1392–1399.
-
(2005)
Blood
, vol.106
, pp. 1392-1399
-
-
Feuerhake, F.1
Kutok, J.L.2
Monti, S.3
-
43
-
-
84941793201
-
Identification of primary mediastinal large B-cell lymphoma at nonmediastinal sites by gene expression profiling
-
Yuan J, Wright G, Rosenwald A, et al. Identification of primary mediastinal large B-cell lymphoma at nonmediastinal sites by gene expression profiling. Am J Surg Pathol 2015;39:1322–1330.
-
(2015)
Am J Surg Pathol
, vol.39
, pp. 1322-1330
-
-
Yuan, J.1
Wright, G.2
Rosenwald, A.3
-
44
-
-
15244350510
-
Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line
-
Melzner I, Bucur AJ, Bruderlein S, et al. Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line. Blood 2005;105:2535–2542.
-
(2005)
Blood
, vol.105
, pp. 2535-2542
-
-
Melzner, I.1
Bucur, A.J.2
Bruderlein, S.3
-
45
-
-
3042552337
-
Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1
-
Marg A, Shan Y, Meyer T, et al. Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol 2004;165:823–833.
-
(2004)
J Cell Biol
, vol.165
, pp. 823-833
-
-
Marg, A.1
Shan, Y.2
Meyer, T.3
-
46
-
-
79952816655
-
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
-
Steidl C, Shah SP, Woolcock BW, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011;471:377–381.
-
(2011)
Nature
, vol.471
, pp. 377-381
-
-
Steidl, C.1
Shah, S.P.2
Woolcock, B.W.3
-
47
-
-
84906273693
-
FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma
-
Xie L, Ritz O, Leithauser F, et al. FOXO1 downregulation contributes to the oncogenic program of primary mediastinal B-cell lymphoma. Oncotarget 2014;5:5392–5402.
-
(2014)
Oncotarget
, vol.5
, pp. 5392-5402
-
-
Xie, L.1
Ritz, O.2
Leithauser, F.3
-
48
-
-
84877791472
-
Targeting the nuclear transport machinery by rational drug design
-
Mao L, Yang Y. Targeting the nuclear transport machinery by rational drug design. Curr Pharma Des 2013;19:2318–2325.
-
(2013)
Curr Pharma Des
, vol.19
, pp. 2318-2325
-
-
Mao, L.1
Yang, Y.2
-
49
-
-
0037438356
-
The GTP-binding domain of class II transactivator regulates its nuclear export
-
Raval A, Weissman JD, Howcroft TK, et al. The GTP-binding domain of class II transactivator regulates its nuclear export. J Immunol 2003;170:922–930.
-
(2003)
J Immunol
, vol.170
, pp. 922-930
-
-
Raval, A.1
Weissman, J.D.2
Howcroft, T.K.3
-
50
-
-
84907021079
-
Understanding XPO1 target networks using systems biology and mathematical modeling
-
Muqbil I, Kauffman M, Shacham S, et al. Understanding XPO1 target networks using systems biology and mathematical modeling. Curr Pharma Des 2014;20:56–65.
-
(2014)
Curr Pharma Des
, vol.20
, pp. 56-65
-
-
Muqbil, I.1
Kauffman, M.2
Shacham, S.3
-
51
-
-
0037417886
-
Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling
-
Swameye I, Muller TG, Timmer J, et al. Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling. Proc Natl Acad Sci USA 2003;100:1028–1033.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1028-1033
-
-
Swameye, I.1
Muller, T.G.2
Timmer, J.3
-
52
-
-
84921442369
-
Identifying drug-target selectivity of small-molecule CRM1/XPO1 inhibitors by CRISPR/Cas9 genome editing
-
Neggers JE, Vercruysse T, Jacquemyn M, et al. Identifying drug-target selectivity of small-molecule CRM1/XPO1 inhibitors by CRISPR/Cas9 genome editing. Chem Biol 2015;22:107–116.
-
(2015)
Chem Biol
, vol.22
, pp. 107-116
-
-
Neggers, J.E.1
Vercruysse, T.2
Jacquemyn, M.3
-
53
-
-
84928653228
-
Nucleo-cytoplasmic transport as a therapeutic target of cancer
-
Gravina G, Senapedis W, McCauley D, et al. Nucleo-cytoplasmic transport as a therapeutic target of cancer. J Hematol Oncol 2014;7:85.
-
(2014)
J Hematol Oncol
, vol.7
, pp. 85
-
-
Gravina, G.1
Senapedis, W.2
McCauley, D.3
-
54
-
-
84904305023
-
Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma
-
Yoshimura M, Ishizawa J, Ruvolo V, et al. Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma. Cancer Sci 2014;105:795–801.
-
(2014)
Cancer Sci
, vol.105
, pp. 795-801
-
-
Yoshimura, M.1
Ishizawa, J.2
Ruvolo, V.3
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