메뉴 건너뛰기




Volumn 22, Issue 12, 2016, Pages 2919-2928

Next-generation sequencing in diffuse large B-cell lymphoma highlights molecular divergence and therapeutic opportunities: A LYSA study

(30)  Dubois, Sydney a   Viailly, Pierre Julien a,b   Mareschal, Sylvain a   Bohers, Elodie a   Bertrand, Philippe a   Ruminy, Philippe a   Maingonnat, Catherine a   Jais, Jean Philippe c   Peyrouze, Pauline d   Figeac, Martin d   Molina, Thierry J c   Desmots, Fabienne e   Fest, Thierry e   Haioun, Corinne f   Lamy, Thierry e   Copie Bergman, Christiane f   Brière, Josette g,h   Petrella, Tony i   Canioni, Danielle c   Fabiani, Bettina j   more..

g INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; STAT PROTEIN; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CELL RECEPTOR; CYCLOPHOSPHAMIDE; DNA BINDING PROTEIN; DOXORUBICIN; EXPORTIN 1 PROTEIN; GNA14 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE; KARYOPHERIN; MFHAS1 PROTEIN, HUMAN; MONOCLONAL ANTIBODY; ONCOPROTEIN; PHOSPHOTRANSFERASE; PREDNISONE; R-CHOP PROTOCOL; TNFAIP3 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; VINCRISTINE;

EID: 84975086212     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-15-2305     Document Type: Article
Times cited : (176)

References (52)
  • 2
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403:503-11.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3    Ma, C.4    Lossos, I.S.5    Rosenwald, A.6
  • 3
    • 0043192901 scopus 로고    scopus 로고
    • A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma
    • Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma. Proc Natl Acad Sci U S A 2003;100:9991-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9991-9996
    • Wright, G.1    Tan, B.2    Rosenwald, A.3    Hurt, E.H.4    Wiestner, A.5    Staudt, L.M.6
  • 4
    • 0036530299 scopus 로고    scopus 로고
    • The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile
    • Huang JZ, Sanger WG, Greiner TC, Staudt LM, Weisenburger DD, Pickering DL, et al. The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile. Blood 2002;99:2285-90.
    • (2002) Blood , vol.99 , pp. 2285-2290
    • Huang, J.Z.1    Sanger, W.G.2    Greiner, T.C.3    Staudt, L.M.4    Weisenburger, D.D.5    Pickering, D.L.6
  • 5
    • 84880672380 scopus 로고    scopus 로고
    • PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma
    • Pfeifer M, Grau M, Lenze D, Wenzel S-S, Wolf A, Wollert-Wulf B, et al. PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A 2013;110:12420-5.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 12420-12425
    • Pfeifer, M.1    Grau, M.2    Lenze, D.3    Wenzel, S.-S.4    Wolf, A.5    Wollert-Wulf, B.6
  • 7
    • 77951010885 scopus 로고    scopus 로고
    • Aggressive lymphomas
    • Lenz G, Staudt LM. Aggressive lymphomas. New Engl J Med 2010;362:1417-29.
    • (2010) New Engl J Med , vol.362 , pp. 1417-1429
    • Lenz, G.1    Staudt, L.M.2
  • 8
    • 10744228934 scopus 로고    scopus 로고
    • The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin
    • Savage K, Monti S, Kutok J, Cattoretti G. The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin. Blood 2003;102:3871-80.
    • (2003) Blood , vol.102 , pp. 3871-3880
    • Savage, K.1    Monti, S.2    Kutok, J.3    Cattoretti, G.4
  • 9
    • 84923268725 scopus 로고    scopus 로고
    • Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells
    • Reichel J, Chadburn A, Rubinstein PG, Giulino-roth L, Tam W, Liu Y, et al. Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells. Blood 2015;125:1061-73.
    • (2015) Blood , vol.125 , pp. 1061-1073
    • Reichel, J.1    Chadburn, A.2    Rubinstein, P.G.3    Giulino-Roth, L.4    Tam, W.5    Liu, Y.6
  • 10
    • 79959852471 scopus 로고    scopus 로고
    • Prognostic significance of immunohistochemical biomarkers in diffuse large B-cell lymphoma: A study from the Lunenburg Lymphoma Biomarker Consortium
    • Salles G, de Jong D, Xie W, Rosenwald A, Chhanabhai M, Gaulard P, et al. Prognostic significance of immunohistochemical biomarkers in diffuse large B-cell lymphoma: a study from the Lunenburg Lymphoma Biomarker Consortium. Blood 2011;117:7070-8.
    • (2011) Blood , vol.117 , pp. 7070-7078
    • Salles, G.1    De Jong, D.2    Xie, W.3    Rosenwald, A.4    Chhanabhai, M.5    Gaulard, P.6
  • 11
    • 84928207042 scopus 로고    scopus 로고
    • Accurate classification of germinal center B-cell-like/activated B-cell-like diffuse large B-cell lymphoma using a simple and rapid reverse transcriptase-multiplex ligation-dependent probe amplification assay: A CALYM Study
    • Apr 9. Epub ahead of print
    • Mareschal S, Ruminy P, Bagacean C, Marchand V, Cornic M, Jais J-P, et al. Accurate classification of germinal center B-cell-like/activated B-cell-like diffuse large B-cell lymphoma using a simple and rapid reverse transcriptase-multiplex ligation-dependent probe amplification assay: A CALYM Study. J Mol Diagn 2015 Apr 9. [Epub ahead of print].
    • (2015) J Mol Diagn
    • Mareschal, S.1    Ruminy, P.2    Bagacean, C.3    Marchand, V.4    Cornic, M.5    Jais, J.-P.6
  • 12
    • 84964994916 scopus 로고    scopus 로고
    • Prognostic significance of diffuse large B-cell lymphoma cell of origin determined by digital gene expression in formalin-fixed paraffin-embedded tissue biopsies
    • Scott DW, Mottok A, Ennishi D, Wright GW, Farinha P, Ben-Neriah S, et al. Prognostic significance of diffuse large B-cell lymphoma cell of origin determined by digital gene expression in formalin-fixed paraffin-embedded tissue biopsies. J of Clin Oncol 2015;33:2848-56.
    • (2015) J of Clin Oncol , vol.33 , pp. 2848-2856
    • Scott, D.W.1    Mottok, A.2    Ennishi, D.3    Wright, G.W.4    Farinha, P.5    Ben-Neriah, S.6
  • 13
    • 84857942952 scopus 로고    scopus 로고
    • Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
    • Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci U S A 2012;109:3879-84.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 3879-3884
    • Lohr, J.G.1    Stojanov, P.2    Lawrence, M.S.3    Auclair, D.4    Chapuy, B.5    Sougnez, C.6
  • 14
    • 84886290682 scopus 로고    scopus 로고
    • Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
    • Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, et al. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood 2013;122:1256-65.
    • (2013) Blood , vol.122 , pp. 1256-1265
    • Morin, R.D.1    Mungall, K.2    Pleasance, E.3    Mungall, A.J.4    Goya, R.5    Huff, R.D.6
  • 15
    • 84893481151 scopus 로고    scopus 로고
    • Genome sequencing of lymphoid malignancies
    • Mullighan CG. Genome sequencing of lymphoid malignancies. Blood 2013;122:3899-907.
    • (2013) Blood , vol.122 , pp. 3899-3907
    • Mullighan, C.G.1
  • 16
    • 75749124332 scopus 로고    scopus 로고
    • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
    • Morin RD, Johnson Na, Severson TM, Mungall AJ, An J, Goya R, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 2010;42:181-5.
    • (2010) Nat Genet , vol.42 , pp. 181-185
    • Morin, R.D.1    Na, J.2    Severson, T.M.3    Mungall, A.J.4    An, J.5    Goya, R.6
  • 18
  • 20
    • 84872856782 scopus 로고    scopus 로고
    • Genetic heterogeneity of diffuse large B-cell lymphoma
    • Zhang J, Grubor V. Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci 2013;110:1398-403.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. 1398-1403
    • Zhang, J.1    Grubor, V.2
  • 21
    • 80052673612 scopus 로고    scopus 로고
    • The molecular pathogenesis of primary mediastinal large B-cell lymphoma
    • Steidl C, Gascoyne RD. The molecular pathogenesis of primary mediastinal large B-cell lymphoma. Blood 2011;118:2659-69.
    • (2011) Blood , vol.118 , pp. 2659-2669
    • Steidl, C.1    Gascoyne, R.D.2
  • 22
    • 69849087246 scopus 로고    scopus 로고
    • Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma
    • Ritz O, Guiter C, Castellano F, Dorsch K, Melzner J, Jais J-P, et al. Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma. Blood 2009;114:1236-42.
    • (2009) Blood , vol.114 , pp. 1236-1242
    • Ritz, O.1    Guiter, C.2    Castellano, F.3    Dorsch, K.4    Melzner, J.5    Jais, J.-P.6
  • 23
    • 84872779378 scopus 로고    scopus 로고
    • Recurrent targets of aberrant somatic hypermutation in lymphoma
    • Khodabakhshi A, Morin R, Fejes A. Recurrent targets of aberrant somatic hypermutation in lymphoma. Oncotarget 2012;3:1308-19.
    • (2012) Oncotarget , vol.3 , pp. 1308-1319
    • Khodabakhshi, A.1    Morin, R.2    Fejes, A.3
  • 24
    • 84932135200 scopus 로고    scopus 로고
    • Activating somatic mutations in diffuse large B-cell lymphomas: Lessons from next generation sequencing and key elements in the precision medicine era
    • Bohers E, Mareschal S, Bertrand P, Viailly PJ, Dubois S, Maingonnat C, et al. Activating somatic mutations in diffuse large B-cell lymphomas: lessons from next generation sequencing and key elements in the precision medicine era. Leuk Lymphoma 2015;56:1213-22.
    • (2015) Leuk Lymphoma , vol.56 , pp. 1213-1222
    • Bohers, E.1    Mareschal, S.2    Bertrand, P.3    Viailly, P.J.4    Dubois, S.5    Maingonnat, C.6
  • 25
    • 84954362895 scopus 로고    scopus 로고
    • Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma
    • Mareschal S, Dubois S, Viailly P-J, Bertrand P, Bohers E, Maingonnat C, et al. Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B-cell lymphoma. Genes Chromosomes Cancer 2015;55:251-67.
    • (2015) Genes Chromosomes Cancer , vol.55 , pp. 251-267
    • Mareschal, S.1    Dubois, S.2    Viailly, P.-J.3    Bertrand, P.4    Bohers, E.5    Maingonnat, C.6
  • 26
    • 84937872378 scopus 로고    scopus 로고
    • Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy?
    • Dubois S, Mareschal S, Picquenot J-M, Viailly P-J, Bohers E, Cornic M, et al. Immunohistochemical and genomic profiles of diffuse large B-cell lymphomas: Implications for targeted EZH2 inhibitor therapy? Oncotarget 2015;6:16712-24.
    • (2015) Oncotarget , vol.6 , pp. 16712-16724
    • Dubois, S.1    Mareschal, S.2    Picquenot, J.-M.3    Viailly, P.-J.4    Bohers, E.5    Cornic, M.6
  • 28
    • 84938994998 scopus 로고    scopus 로고
    • Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma
    • Wilson WH, Young RM, Schmitz R, Yang Y, Pittaluga S, Wright G, et al. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Nature Med 2015;21:922-6.
    • (2015) Nature Med , vol.21 , pp. 922-926
    • Wilson, W.H.1    Young, R.M.2    Schmitz, R.3    Yang, Y.4    Pittaluga, S.5    Wright, G.6
  • 29
    • 84899081280 scopus 로고    scopus 로고
    • Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment
    • Zheng X, Ding N, Song Y, Feng L, Zhu J. Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment. Cancer Cell Int 2014;14:32.
    • (2014) Cancer Cell Int , vol.14 , pp. 32
    • Zheng, X.1    Ding, N.2    Song, Y.3    Feng, L.4    Zhu, J.5
  • 30
    • 79953323846 scopus 로고    scopus 로고
    • Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas
    • Naylor TL, Tang H, Ratsch BA, Enns A, Loo A, Chen L, et al. Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas. Cancer Res 2011;71:2643-53.
    • (2011) Cancer Res , vol.71 , pp. 2643-2653
    • Naylor, T.L.1    Tang, H.2    Ratsch, B.A.3    Enns, A.4    Loo, A.5    Chen, L.6
  • 32
    • 84862152044 scopus 로고    scopus 로고
    • Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
    • Yang Y, Shaffer AL, Emre NCT, Ceribelli M, Zhang M, Wright G, et al. Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma. Cancer Cell 2012;21:723-37.
    • (2012) Cancer Cell , vol.21 , pp. 723-737
    • Yang, Y.1    Shaffer, A.L.2    Emre, N.C.T.3    Ceribelli, M.4    Zhang, M.5    Wright, G.6
  • 33
    • 84864326041 scopus 로고    scopus 로고
    • PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma
    • Brault L, Menter T, Obermann EC, Knapp S, Thommen S, Schwaller J, et al. PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma. Br J Cancer 2012;107:491-500.
    • (2012) Br J Cancer , vol.107 , pp. 491-500
    • Brault, L.1    Menter, T.2    Obermann, E.C.3    Knapp, S.4    Thommen, S.5    Schwaller, J.6
  • 35
    • 84868602463 scopus 로고    scopus 로고
    • Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with rituximab-CHOP: A report from an International DLBCL Rituximab-CHOP Consortium Program study
    • Xu-Monette ZY, Wu L, Visco C, Tai YC, Tzankov A, Liu W -M, et al. Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with rituximab-CHOP: a report from an International DLBCL Rituximab-CHOP Consortium Program study. Blood 2012;120:3986-97.
    • (2012) Blood , vol.120 , pp. 3986-3997
    • Xu-Monette, Z.Y.1    Wu, L.2    Visco, C.3    Tai, Y.C.4    Tzankov, A.5    Liu, W.-M.6
  • 36
    • 84867051939 scopus 로고    scopus 로고
    • Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    • Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao W, Zhang M, et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012;490:116-20.
    • (2012) Nature , vol.490 , pp. 116-120
    • Schmitz, R.1    Young, R.M.2    Ceribelli, M.3    Jhavar, S.4    Xiao, W.5    Zhang, M.6
  • 37
    • 84938954876 scopus 로고    scopus 로고
    • The diagnostic gray zone between Burkitt lymphoma and diffuse large B-cell lymphoma is also a gray zone of the mutational spectrum
    • Momose S, Weißbach S, Pischimarov J, Nedeva T, Bach E, Rudelius M, et al. The diagnostic gray zone between Burkitt lymphoma and diffuse large B-cell lymphoma is also a gray zone of the mutational spectrum. Leukemia 2015;29:1789-91.
    • (2015) Leukemia , vol.29 , pp. 1789-1791
    • Momose, S.1    Weißbach, S.2    Pischimarov, J.3    Nedeva, T.4    Bach, E.5    Rudelius, M.6
  • 39
    • 33646382121 scopus 로고    scopus 로고
    • Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
    • Weniger MA, Melzner I, Menz CK, Wegener S, Bucura J, Dorsch K, et al. Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation. Oncogene 2006;25:2679-84.
    • (2006) Oncogene , vol.25 , pp. 2679-2684
    • Weniger, M.A.1    Melzner, I.2    Menz, C.K.3    Wegener, S.4    Bucura, J.5    Dorsch, K.6
  • 41
    • 79952816655 scopus 로고    scopus 로고
    • MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
    • Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011;471:377-81.
    • (2011) Nature , vol.471 , pp. 377-381
    • Steidl, C.1    Shah, S.P.2    Woolcock, B.W.3    Rui, L.4    Kawahara, M.5    Farinha, P.6
  • 42
    • 34548745426 scopus 로고    scopus 로고
    • Inositol 1, 3, 4, 5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells
    • Maréchal Y, Pesesse X, Jia Y, Pouillon V, Perez-Morga D, Daniel J, et al. Inositol 1, 3, 4, 5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells. Proc Natl Acad Sci 2007;104:13978-83.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 13978-13983
    • Maréchal, Y.1    Pesesse, X.2    Jia, Y.3    Pouillon, V.4    Perez-Morga, D.5    Daniel, J.6
  • 43
    • 1942501050 scopus 로고    scopus 로고
    • MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8
    • Tagawa H, Karnan S, Kasugai Y, Tuzuki S, Suzuki R, Hosokawa Y, et al. MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8. Oncogene 2004;23:2576-81.
    • (2004) Oncogene , vol.23 , pp. 2576-2581
    • Tagawa, H.1    Karnan, S.2    Kasugai, Y.3    Tuzuki, S.4    Suzuki, R.5    Hosokawa, Y.6
  • 44
    • 84891866590 scopus 로고    scopus 로고
    • SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients
    • Jeromin S, Weissmann S, Haferlach C, Dicker F, Bayer K, Grossmann V, et al. SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients. Leukemia 2014;28:108-17.
    • (2014) Leukemia , vol.28 , pp. 108-117
    • Jeromin, S.1    Weissmann, S.2    Haferlach, C.3    Dicker, F.4    Bayer, K.5    Grossmann, V.6
  • 45
    • 84870502798 scopus 로고    scopus 로고
    • Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
    • Lapalombella R, Sun Q, Williams K, Tangeman L, Jha S, Zhong Y, et al. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood 2012;120:4621-34.
    • (2012) Blood , vol.120 , pp. 4621-4634
    • Lapalombella, R.1    Sun, Q.2    Williams, K.3    Tangeman, L.4    Jha, S.5    Zhong, Y.6
  • 46
    • 84986205572 scopus 로고    scopus 로고
    • Recurrent mutations of the Exportin 1 gene (XPO1) in primary mediastinal B-Cell Lymphoma: A Lysa Study
    • Jardin F, Pujals A, Pelletier L, Bohers E, Camus V, Mareschal S, et al. Recurrent mutations of the Exportin 1 gene (XPO1) in primary mediastinal B-Cell Lymphoma: A Lysa Study. Blood 2015;126:129.
    • (2015) Blood , vol.126 , pp. 129
    • Jardin, F.1    Pujals, A.2    Pelletier, L.3    Bohers, E.4    Camus, V.5    Mareschal, S.6
  • 47
    • 82855177864 scopus 로고    scopus 로고
    • The proportion of activated B-cell like subtype among de novo diffuse large B-cell lymphoma increases with age
    • Mareschal S, Lanic H, Ruminy P, Bastard C, Tilly H, Jardin F. The proportion of activated B-cell like subtype among de novo diffuse large B-cell lymphoma increases with age. Haematologica 2011;96:1888-90.
    • (2011) Haematologica , vol.96 , pp. 1888-1890
    • Mareschal, S.1    Lanic, H.2    Ruminy, P.3    Bastard, C.4    Tilly, H.5    Jardin, F.6
  • 49
    • 82255186682 scopus 로고    scopus 로고
    • Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): An open-label randomised phase 3 trial
    • Récher C, Coiffier B, Haioun C, Molina TJ, Fermé C, Casasnovas O, et al. Intensified chemotherapy with ACVBP plus rituximab versus standard CHOP plus rituximab for the treatment of diffuse large B-cell lymphoma (LNH03-2B): an open-label randomised phase 3 trial. Lancet 2011;378:1858-67.
    • (2011) Lancet , vol.378 , pp. 1858-1867
    • Récher, C.1    Coiffier, B.2    Haioun, C.3    Molina, T.J.4    Fermé, C.5    Casasnovas, O.6
  • 52
    • 84975066748 scopus 로고    scopus 로고
    • Somatic mutations of cell-free circulating DNA detected by next generation sequencing reflect the genetic changes in both germinal center B-cell like and activated B-cell like diffuse large B-cell lymphoma tumors at the time of diagnosis
    • Bohers E, Viailly P-J, Dubois S, Bertrand P, Maingonnat C, Mareschal S, et al. Somatic mutations of cell-free circulating DNA detected by next generation sequencing reflect the genetic changes in both germinal center B-cell like and activated B-cell like diffuse large B-cell lymphoma tumors at the time of diagnosis. Haematologica 2011;96:1589-94.
    • (2011) Haematologica , vol.96 , pp. 1589-1594
    • Bohers, E.1    Viailly, P.-J.2    Dubois, S.3    Bertrand, P.4    Maingonnat, C.5    Mareschal, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.