Admission hyperglycemia is associated with different outcomes after blunt versus penetrating trauma

Journal of Surgical Research

Volumn 206, Issue 1, 2016, Pages 83-89

  Meizoso, Jonathan P ^a   Ray, Juliet J ^a   Karcutskie, Charles A ^a   Teisch, Laura F ^a   Allen, Casey J ^a   Namias, Nicholas ^a   Schulman, Carl I ^a   Proctor, Kenneth G ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Blunt trauma; Glucose; Hyperglycemia; Mortality; Penetrating trauma

Indexed keywords

GLUCOSE;

ADULT; BLUNT TRAUMA; COHORT ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPERGLYCEMIA; INFECTIOUS COMPLICATION; INJURY SCALE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PENETRATING TRAUMA; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; ADOLESCENT; AGED; COMPARATIVE STUDY; COMPLICATION; INFECTION; MIDDLE AGED; PROGNOSIS; RISK FACTOR; STATISTICAL MODEL; VERY ELDERLY; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; HYPERGLYCEMIA; INFECTION; INJURY SEVERITY SCORE; LOGISTIC MODELS; MALE; MIDDLE AGED; PATIENT ADMISSION; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; WOUNDS, NONPENETRATING; WOUNDS, PENETRATING; YOUNG ADULT;

EID: 84982812058     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2016.07.012     Document Type: Conference Paper

References (37)

1. 1 Zolin, S.J., Vodovotz, Y., Forsythe, R.M., et al. The early evolving sex hormone environment is associated with significant outcome and inflammatory response differences after injury. J Trauma Acute Care Surg 78 (2015), 451–457 discussion 457–458.
2. 2 Heffernan, D.S., Dossett, L.A., Lightfoot, M.A., et al. Gender and acute respiratory distress syndrome in critically injured adults: a prospective study. J Trauma 71 (2011), 878–883 discussion 883–875.
3. 3 Rowell, S.E., Barbosa, R.R., Allison, C.E., et al. Gender-based differences in mortality in response to high product ratio massive transfusion. J Trauma 71 (2011), S375–S379.
4. 4 Allen, C.J., Hannay, W.M., Murray, C.R., et al. Causes of death differ between elderly and adult falls. J Trauma Acute Care Surg 79 (2015), 617–621.
5. 5 Allen, C.J., Ruiz, X.D., Meizoso, J.P., et al. Is hydroxyethyl starch safe in penetrating trauma patients?. Mil Med 181 (2016), 152–155.
6. 6 Allen, C.J., Valle, E.J., Jouria, J.M., et al. Differences between blunt and penetrating trauma after resuscitation with hydroxyethyl starch. J Trauma Acute Care Surg 77 (2014), 859–864.
7. 7 Ryan, M.L., Ogilvie, M.P., Pereira, B.M., et al. Effect of hetastarch bolus in trauma patients requiring emergency surgery. J Spec Oper Med 12 (2012), 57–67.
8. 8 Holcomb, J.B., Fluid resuscitation in modern combat casualty care: lessons learned from Somalia. J Trauma 54 (2003), S46–S51.
9. 9 McSwain, N.E., Champion, H.R., Fabian, T.C., et al. State of the art of fluid resuscitation 2010: prehospital and immediate transition to the hospital. J Trauma 70 (2011), S2–S10.
10. 10 James, M.F., Michell, W.L., Joubert, I.A., et al. Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma). Br J Anaesth 107 (2011), 693–702.
11. 11 McCowen, K.C., Malhotra, A., Bistrian, B.R., Stress-induced hyperglycemia. Crit Care Clin 17 (2001), 107–124.
12. 12 Kohl, B.A., Deutschman, C.S., The inflammatory response to surgery and trauma. Curr Opin Crit Care 12 (2006), 325–332.
13. 13 Jeschke, M.G., Finnerty, C.C., Herndon, D.N., et al. Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response. Ann Surg 255 (2012), 370–378.
14. 14 McNamara, J.J., Molot, M., Stremple, J.F., et al. Hyperglycemic response to trauma in combat casualties. J Trauma 11 (1971), 337–339.
15. 15 Yendamuri, S., Fulda, G.J., Tinkoff, G.H., Admission hyperglycemia as a prognostic indicator in trauma. J Trauma 55 (2003), 33–38.
16. 16 Laird, A.M., Miller, P.R., Kilgo, P.D., et al. Relationship of early hyperglycemia to mortality in trauma patients. J Trauma 56 (2004), 1058–1062.
17. 17 Bochicchio, G.V., Salzano, L., Joshi, M., et al. Admission preoperative glucose is predictive of morbidity and mortality in trauma patients who require immediate operative intervention. Am Surg 71 (2005), 171–174.
18. 18 Mohr, A.M., Lavery, R.F., Sifri, Z.C., et al. Gender differences in glucose variability after severe trauma. Am Surg 76 (2010), 896–902.
19. 19 Sung, J., Bochicchio, G.V., Joshi, M., et al. Admission hyperglycemia is predictive of outcome in critically ill trauma patients. J Trauma 59 (2005), 80–83.
20. 20 Duane, T.M., Dechert, T., Dalesio, N., et al. Is blood sugar the next lactate?. Am Surg 72 (2006), 613–617 discussion 617–618.
21. 21 Kreutziger, J., Rafetseder, A., Mathis, S., et al. Admission blood glucose predicted haemorrhagic shock in multiple trauma patients. Injury 46 (2015), 15–20.
22. 22 Kreutziger, J., Schlaepfer, J., Wenzel, V., et al. The role of admission blood glucose in outcome prediction of surviving patients with multiple injuries. J Trauma 67 (2009), 704–708.
23. 23 Kreutziger, J., Wenzel, V., Kurz, A., et al. Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients. Intensive Care Med 35 (2009), 1234–1239.
24. 24 Kerby, J.D., Griffin, R.L., MacLennan, P., et al. Stress-induced hyperglycemia, not diabetic hyperglycemia, is associated with higher mortality in trauma. Ann Surg 256 (2012), 446–452.
25. 25 Allen, C.J., Ruiz, X.D., Meizoso, J.P., et al. Is hydroxyethyl starch safe in penetrating trauma patients?. Mil Med 181:5S (2016), 152–155.
26. 26 Amaral, J.F., Caldwell, M.D., Metabolic response to starvation, stress, and sepsis. Miller, T.A., (eds.) Physiologic Basis of Modern Surgical Care, 1988, Mosby, St. Louis.
27. 27 Meakins, J.L., McLean, A.P., Kelly, R., et al. Delayed hypersensitivity and neutrophil chemotaxis: effect of trauma. J Trauma 18 (1978), 240–247.
28. 28 Christou, N.V., McLean, A.P., Meakins, J.L., Host defense in blunt trauma: interrelationships of kinetics of anergy and depressed neutrophil function, nutritional status, and sepsis. J Trauma 20 (1980), 833–841.
29. 29 Skillman, J.J., Hedley-Whyte, J., Pallotta, J.A., Cardiorespiratory, metabolic and endocrine changes after hemorrhage in man. Ann Surg 174 (1971), 911–922.
30. 30 Lindsey, A., Santeusanio, F., Braaten, J., et al. Pancreatic alpha-cell function in trauma. JAMA 227 (1974), 757–761.
31. 31 Bochicchio, G.V., Bochicchio, K.M., Joshi, M., et al. Acute glucose elevation is highly predictive of infection and outcome in critically injured trauma patients. Ann Surg 252 (2010), 597–602.
32. 32 Becher, R.D., Meredith, J.W., Kilgo, P.D., Injury severity scoring and outcomes research. Mattox, K.L., Moore, E.E., Feliciano, D.V., (eds.) Trauma, 7 ed., 2013, McGraw-Hill, New York.
33. 33 Wahl, W.L., Taddonio, M., Maggio, P.M., et al. Mean glucose values predict trauma patient mortality. J Trauma 65 (2008), 42–47 discussion 47–48.
34. 34 Sperry, J.L., Frankel, H.L., Vanek, S.L., et al. Early hyperglycemia predicts multiple organ failure and mortality but not infection. J Trauma 63 (2007), 487–493 discussion 493–484.
35. 35 van den Berghe, G., Wouters, P., Weekers, F., et al. Intensive insulin therapy in critically ill patients. N Engl J Med 345 (2001), 1359–1367.
36. 36 NICE-SUGAR Study Investigators. Hypoglycemia and risk of death in critically ill patients. N Engl J Med 367 (2012), 1108–1118.
37. 37 Centers for Disease Control: Diabetes Public Health Resource. Available at: http://www.cdc.gov/diabetes/statistics/prev/national/figageadult.htm. Accessed 04/01/2015.