Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: The FIRST trial (Fluids in Resuscitation of Severe Trauma)

British Journal of Anaesthesia

Volumn 107, Issue 5, 2011, Pages 693-702

  James, M F M ^a   Michell, W L ^a   Joubert, I A ^a   Nicol, A J ^a   Navsaria, P H ^a   Gillespie, R S ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

acute kidney injury; fluid therapy; hydroxyethyl starch; saline solutions; trauma

Indexed keywords

HETASTARCH; LACTIC ACID; SODIUM CHLORIDE;

ADULT; ARTERIAL PRESSURE; ARTICLE; BLOOD CLOTTING; BLUNT TRAUMA; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; CONVALESCENCE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE VOLUME; FEMALE; FLUID RESUSCITATION; FOLLOW UP; GASTROINTESTINAL TRACT FUNCTION; GUNSHOT INJURY; HEART RATE; HEMODYNAMICS; HUMAN; INJURY SEVERITY; INTESTINE FUNCTION; KIDNEY CLEARANCE; KIDNEY FUNCTION; KIDNEY INJURY; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PATIENT SAFETY; PENETRATING TRAUMA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESUSCITATION; SHOCK; STAB WOUND; THROMBOELASTOGRAPHY; TRAFFIC ACCIDENT;

EID: 80054107339     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aer229     Document Type: Article

References (33)

1. Shoemaker WC, Wo CC. Circulatory effects of whole blood, packed red cells, albumin, starch, and crystalloids in resuscitation of shock and acute critical illness. Vox Sang 1998;74(Suppl. 2):69-74
2. Roberts I, Alderson P, Bunn F, Chinnock P, Ker K, Schierhout G. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev 2004;CD000567
3. Balogh Z, McKinley BA, Cocanour CS, et al. Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome. Arch Surg 2003;138:637-42
4. Madigan MC, Kemp CD, Johnson JC, Cotton BA. Secondary abdominal compartment syndrome after severe extremity injury: are early, aggressive fluid resuscitation strategies to blame? J Trauma 2008;64:280-5
5. Westphal M, James MF, Kozek-Langenecker S, Stocker R, Guidet B, Van Aken H. Hydroxyethyl starches: different products-different effects. Anesthesiology 2009;111:187-202
6. Shafi S, Kauder DR. Fluid resuscitation and blood replacement in patients with polytrauma. Clin Orthop Rel Res 2004;422:37-42
7. Santry HP, Alam HB. Fluid resuscitation: past, present, and the future. Shock 2010;33:229-41
8. Bagshaw SM, Uchino S, Cruz D, et al. A comparison of observed versus estimated baseline creatinine for determination of RIFLE class in patients with acute kidney injury. Nephrol Dial Transplant 2009;24:2739-44
9. Ogilvie MP, Pereira BM, McKenney MG, et al. First report on safety and efficacy of hetastarch solution for initial fluid resuscitation at a level 1 trauma center. J Am Coll Surg 2010;210:870-2
10. Grocott MP, Mythen MG, Gan TJ. Perioperative fluid management and clinical outcomes in adults. Anesth Analg 2005;100:1093-106
11. Berkenstadt H, Friedman Z, Preisman S, Keidan I, Livingstone D, Perel A. Pulse pressure and stroke volume variations during severe haemorrhage in ventilated dogs. Br J Anaesth 2005;94:721-6
12. Chytra I, Pradl R, Bosman R, Pelnar P, Kasal E, Zidkova A. Esophageal Doppler-guided fluid management decreases blood lactate levels in multiple-trauma patients: a randomized controlled trial. Crit Care 2007;11:R24
13. Brandstrup B, Tonnesen H, Beier-Holgersen R, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg 2003;238:641-8
14. Nisanevich V, Felsenstein I, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005;103:25-32
15. Oda J, Yamashita K, Inoue T, et al. Resuscitation fluid volume and abdominal compartment syndrome in patients with major burns. Burns 2006;32:151-4
16. Azzopardi EA, McWilliams B, Iyer S, Whitaker IS. Fluid resuscitation in adults with severe burns at risk of secondary abdominal compartment syndrome-an evidence based systematic review. Burns 2009;35:911-20
17. Langeron O, Doelberg M, Ang ET, Bonnet F, Capdevila X, Coriat P. Voluven, a lower substituted novel hydroxyethyl starch (HES 130/0.4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0.5. Anesth Analg 2001;92:855-62
18. Van der Linden PJ, De Hert SG, Deraedt D, et al. Hydroxyethyl starch 130/0.4 versus modified fluid gelatin for volume expansion in cardiac surgery patients: the effects on perioperative bleeding and transfusion needs. Anesth Analg 2005;101:629-34
19. Kozek-Langenecker SA, Jungheinrich C, Sauermann W, Van der Linden P. The effects of hydroxyethyl starch 130/0.4 (6%) on blood loss and use of blood products in major surgery: a pooled analysis of randomized clinical trials. Anesth Analg 2008;107:382-90
20. Casutt M, Kristoffy A, Schuepfer G, Spahn DR, Konrad C. Effects on coagulation of balanced (130/0.42) and non-balanced (130/0.4) hydroxyethyl starch or gelatin compared with balanced Ringer's solution: an in vitro study using two different viscoelastic coagulation tests ROTEM®and SONOCLOT®. Br J Anaesth 2010;105:273-81
21. Schramko AA, Suojaranta-Ylinen RT, Kuitunen AH, Kukkonen SI, Niemi TT. Rapidly degradable hydroxyethyl starch solutions impair blood coagulation after cardiac surgery: a prospective randomized trial. Anesth Analg 2009;108:30-6
22. Brohi K, Cohen MJ, Ganter MT, et al. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma 2008;64:1211-7
23. Hess JR, Brohi K, Dutton RP, et al. The coagulopathy of trauma: a review of mechanisms. J Trauma 2008;65:748-54
24. Hartog CS, Bauer M, Reinhart K. Review article: the efficacy and safety of colloid resuscitation in the critically ill. Anesth Analg 2011;112:156-64
25. Cittanova ML, Leblanc I, Legendre C, Mouquet C, Riou B, Coriat P. Effect of hydroxyethylstarch in brain-dead kidney donors on renal function in kidney-transplant recipients. Lancet 1996;348:1620-2
26. Schortgen F, Lacherade JC, Bruneel F, et al. Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study. Lancet 2001;357:911-6
27. Brunkhorst FM, Engel C, Bloos F, et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008;358:125-39
28. Schortgen F, Girou E, Deye N, Brochard L. The risk associated with hyperoncotic colloids in patients with shock. Intensive Care Med 2008;34:2157-68
29. Sakr Y, Payen D, Reinhart K, et al. Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 2007;98:216-24
30. Neff TA, Doelberg M, Jungheinrich C, Sauerland A, Spahn DR, Stocker R. Repetitive large-dose infusion of the novel hydroxyethyl starch 130/0.4 in patients with severe head injury. Anesth Analg 2003;96:1453-9
31. Mahmood A, Gosling P, Vohra RK. Randomized clinical trial comparing the effects on renal function of hydroxyethyl starch or gelatine during aortic aneurysm surgery. Br J Surg 2007;94:427-33
32. Balkamou X, Xanthos T, Stroumpoulis K, et al. Hydroxyethyl starch 6% (130/0.4) ameliorates acute lung injury in swine hemorrhagic shock. Anesthesiology 2010;113:1092-8
33. Dubin A, Pozo MO, Casabella CA, et al. Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients. J Crit Care 2010;25:659, e1-8