Gender differences in glucose variability after severe trauma

American Surgeon

Volumn 76, Issue 8, 2010, Pages 896-902

  Mohr, Alicia M ^a   Lavery, Robert F ^a   Sifri, Ziad C ^a   Anjaria, Devashish J ^a   Koernig, Robert ^a   Deitch, Edwin A ^a   Livingston, David H ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GLUCOSE; LACTIC ACID;

ADOLESCENT; ADULT; ARTICLE; BACTEREMIA; BLOOD GLUCOSE VARIABILITY; BLUNT TRAUMA; CORRELATION ANALYSIS; DEATH; DIABETES MELLITUS; ENDOCRINE DISEASE; ENTERIC FEEDING; FEMALE; GLASGOW COMA SCALE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HOSPITAL ADMISSION; HUMAN; INCIDENCE; INJURY SCALE; INJURY SEVERITY; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OBSERVATIONAL STUDY; PENETRATING TRAUMA; PNEUMONIA; PREDICTION; RETROSPECTIVE STUDY; SEX DIFFERENCE; SHOCK; SYSTOLIC BLOOD PRESSURE; HOMEOSTASIS; INJURY; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADULT; BLOOD GLUCOSE; FEMALE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEX FACTORS; WOUNDS AND INJURIES;

EID: 77956217296     PISSN: 00031348     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Laird AM, Miller PR, Kilgo PD, et al. Relationship of early hyperglycemia to mortality in trauma patients. J Trauma 2004;56:1058-62.
2. Sung J, Bochicchio GV, Joshi M, et al. Admission hyperglycemia is predictive of outcome in critically ill trauma patients. J Trauma 2005;59:80-3.
3. Yendamuri S, Fulda GJ, Tinkoff GH. Admission hyperglycemia as a prognostic indicator in trauma. J Trauma 2003;55:33-8.
4. Bochicchio GV, Sung J, Joshi M, et al. Persistent hyperglycemia is predictive of outcome in critically ill trauma patients. J Trauma 2005;58:921-4.
5. Sperry JL, Frankel HL, Nathens AB, et al. Characterization of persistent hyperglycemia: what does it mean postinjury? J Trauma 2009;66:1076-82.
6. Sperry J, Frankel H, Vanek S, et al. Early hyperglycemia predicts multiple organ failure and mortality but not infection. J Trauma 2007;63:487-93.
7. Egi M, Bellomo R, Stachowski E, et al. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology 2006;105:244-52.
8. Dossett LA, Cao H, Mowery NT, et al. Blood glucose variability is associated with mortality in the surgical intensive care unit. Am Surg 2008;74:679-85.
9. Krinsley JS. Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med 2008;36:3008-13.
10. Van Den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001;345:1359-67.
11. Angele MK, Frantz MC, Chaudry IH. Gender and sex hormones influence the response to trauma and sepsis-potential therapeutic approaches. Clinics 2006;61:479-88.
12. Kher A, Wang M, Tsai BM, et al. Sex differences in the myocardial inflammatory response to acute injury. Shock 2005;23:1-10.
13. George RL, McGwin G Jr, Windham ST, et al. Age-related gender differential in outcome after blunt or penetrating trauma. Shock 2003;19:28-32.
14. Deitch EA, Livingston DH, Lavery RF, et al. Hormonally active women tolerate shock-trauma better than do men. Ann Surg 2007;246:447-55.
15. Gore DC, Chinkes D, Heggers J, et al. Association of hyperglycemia with increased mortality after severe burn injury. J Trauma 2001;51:540-4.
16. Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet 2000;355:773-8.
17. Goins WA, Reynolds HN, Nyanjom D, Dunham CM. Outcome following prolonged intensive care unit stay in multiple trauma patients. Crit Care Med 1991;19:339-45.
18. Collier B, Diaz J Jr, Forbes R, et al. The impact of normoglycemic management protocol on clinical outcomes in the trauma intensive care unit. J Parenter Enteral Nutr 2005;29:353-9.
19. Finney SJ, Zekveld C, Elia A, Evans TW. Glucose control and mortality in critically ill patients. JAMA 2003;209:204-7.
20. Zimmerman CR, Mlynarek ME, Jordan JA, et al. An insulin infusion protocol in critically ill cardiothoracic surgery patients. Ann Pharmacother 2004;38:1123-9.
21. Umpierrez GE, Isaacs SD, Bazargan N, et al. Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab 2002;87:978-82.
22. Lindmark S, Wiklund U, Bjerle P, Ericksson JW. Does the autonomic nervous system play a role in the development of insulin resistance? Diabet Med 2003;20:399-405.
23. Fonseca RB, Mohr AM, Wang L, et al. Adrenergic modulation of erythropoiesis in severely injured patients is mediated through bonemarrow stroma. Surg Infect (Larchmt) 2004;5:385-93.
24. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-20.
25. Devos P, Preiser JC. Current controversies around tight glucose control in critically ill patients. Curr Opin Clin Nutr Metab Care 2007;10:206-9.
26. Hirsch IB, Brownlee M. Should minimal blood glucose variability become the gold standard of glycemic control? J Diabetes Complications 2005;19:178-81.
27. 1C levels than glucose instability. Diabetes Care 2006;29:352-5.
28. Vogelzang M, vad der Horst ICC, Nijsten MWN. Hyperglycemic index as a tool to assess glucose control: a retrospective study. Crit Care 2004;8:R122-7.
29. Choudhry MA, Bland K, Chaudry IH. Gender and susceptibility to sepsis following trauma. Endocr Metab Immune Disord Drug Targets 2006;6:127-35.
30. Deitch EA, Feketeova E, Lu Q, et al. Resistance of the female, as opposed to the male, intestine to I/R mediated injury is associated with increased resistance to gut-induced distant organ injury. Shock 2008;29:78-83.
31. Wichmann MW, Zellweger R, DeMaso CM, et al. Enhanced immune responses in females as opposed to decreased responses in males following hemorrhagic shock and resuscitation. Cytokine 1996;8:853-63.
32. Zellweger R, Wichmann MW, Ayala A, et al. Females in proestrus state maintain better splenic immune functions and tolerate sepsis better than males. Crit Care Med 1997;25:106-10.
33. Goodman-Gruen D, Barrett-Connor E. Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women. Diabetes Care 2000;23:912-8.
34. Hsieh YC, Frink M, Choudry MA, et al. Metabolic modulators following trauma sepsis: sex hormones. Crit Care Med 2007;35:S621-9.
35. Andersson B, Mattsson LA, Hahn L, et al. Estrogen replacement therapy decreases hyperandrogenicity and improves glucose homeostasis and plasma lipids in postmenopausal women with non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab 1997;82:638-43.
36. Brussaard HE, Gevers Leuven JA, Freolich M, et al. Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in post-menopausal women with NIDDM. Diabetologia 1997;40:843-9.
37. McMahon MM, Bistrian BR. Host defenses and susceptibility to infection in patients with diabetes mellitus. Infect Dis Clin North Am 1995;9:1-9.
38. Pomposelli JJ, Baxter JK, Babineau TJ, et al. Early postoperative glucose control predicts nosocomial infection rate in diabetic patients. J Parenter Enteral Nutr 1998;22:77-81.