In β-actin knockouts, epigenetic reprogramming and rDNA transcription inactivation lead to growth and proliferation defects

FASEB Journal

Volumn 30, Issue 8, 2016, Pages 2860-2873

  Almuzzaini, Bader ^a,b   Sarshad, Aishe A ^a,e   Rahmanto, Aldwin S ^a   Hansson, Magnus L ^a   Von Euler, Anne ^c   Sangfelt, Olle ^a   Visa, Neus ^c   Farrants, Ann Kristin Östlund ^c   Percipalle, Piergiorgio ^a,c,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KING ABDULLAH INTERNATIONAL MEDICAL RESEARCH CENTER   (Saudi Arabia)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d NEW YORK UNIVERSITY ABU DHABI   (United Arab Emirates)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Genome wide analysis; NM1; Nuclear actin; RRNA synthesis

Indexed keywords

BETA ACTIN; DNA DIRECTED RNA POLYMERASE; FIBRILLARIN; HETEROCHROMATIN PROTEIN 1; HISTONE H3; MYOSIN; NOCODAZOLE; RIBOSOME DNA; RIBOSOME RNA; RNA 18S; RNA 28S; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TTF1; UNCLASSIFIED DRUG; ACTIN; CHROMATIN; MYO1C PROTEIN, MOUSE; MYOSIN I;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; DNA TRANSCRIPTION; DOWN REGULATION; EMBRYO; EPIGENETICS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; METHYLATION; MITOSIS; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA SYNTHESIS; STEADY STATE; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; TRANSMISSION ELECTRON MICROSCOPY; UNTRANSLATED REGION; UPREGULATION; ANIMAL; CELL CULTURE; CHROMATIN; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEAR REPROGRAMMING; PHYSIOLOGY;

ACTINS; ANIMALS; CELLS, CULTURED; CELLULAR REPROGRAMMING; CHROMATIN; DNA, RIBOSOMAL; EPIGENESIS, GENETIC; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MYOSIN TYPE I; POL1 TRANSCRIPTION INITIATION COMPLEX PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84982710701     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201600280R     Document Type: Article

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