Synthetic Lipoteichoic Acid Glycans Are Potential Vaccine Candidates to Protect from Clostridium difficile Infections

Cell Chemical Biology

Volumn 23, Issue 8, 2016, Pages 1014-1022

  Broecker, Felix ^a,b   Martin, Christopher E ^a,b   Wegner, Erik ^c   Mattner, Jochen ^c   Baek, Ju Yuel ^a   Pereira, Claney L ^a   Anish, Chakkumkal ^a   Seeberger, Peter H ^a,b  

^a MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

carbohydrates; Clostridium difficile; lipoteichoic acid; LTA; vaccine

Indexed keywords

B7 ANTIGEN; BACTERIAL VACCINE; CD86 ANTIGEN; DIPHTHERIA TOXOID CRM197; FREUND ADJUVANT; GLYCOCONJUGATE; GLYCOCONJUGATE VACCINE; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; LIPOTEICHOIC ACID GLYCAN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; POLYSACCHARIDE; TEICHOIC ACID;

ANIMAL CELL; ARTICLE; BACTERIAL COLONIZATION; CLOSTRIDIUM BIFERMENTANS; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; INFECTION PREVENTION; INNATE IMMUNITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; SALMONELLA ENTERICA; STREPTOCOCCUS PNEUMONIAE; VACCINATION; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW CELL; CELL DIFFERENTIATION; CHEMISTRY; CLOSTRIDIUM INFECTION; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; PEPTOCLOSTRIDIUM DIFFICILE; SYNTHESIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL VACCINES; BONE MARROW CELLS; CELL DIFFERENTIATION; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; FEMALE; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; POLYSACCHARIDES; TEICHOIC ACIDS;

EID: 84982228048     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2016.07.009     Document Type: Article

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