Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism

Blood

Volumn 125, Issue 10, 2015, Pages 1562-1565

  Liu, Xia ^a   Zheng, Hong ^a,b   Yu, Wen Mei ^a,b   Cooper, Todd M ^b   Bunting, Kevin D ^a,b   Qu, Cheng Kui ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE KINASE; ALEXIDINE DIHYDROCHLORIDE; ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; ALEXIDINE; ANTIDIABETIC AGENT; BIGUANIDE DERIVATIVE; ENZYME INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTPMT1 PROTEIN, MOUSE;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DIFFERENTIATION; CELL METABOLISM; CELL REPROGRAMMING TECHNIQUE; ENERGY METABOLISM; EX VIVO STUDY; GLYCOLYSIS; HEMATOPOIETIC STEM CELL; MICROENVIRONMENT; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; NUCLEAR REPROGRAMMING;

AEROBIOSIS; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BIGUANIDES; CELL DIFFERENTIATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; ENZYME ACTIVATION; ENZYME INHIBITORS; GLYCOLYSIS; HEMATOPOIETIC STEM CELLS; HYPOGLYCEMIC AGENTS; METFORMIN; MICE; OXYGEN CONSUMPTION; PTEN PHOSPHOHYDROLASE;

EID: 84982182491     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-04-568949     Document Type: Article

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