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Volumn 22, Issue 16, 2016, Pages 4215-4224

Improved risk assessment by integrating molecular and clinicopathological factors in early-stage endometrial cancer-combined analysis of the PORTEC cohorts

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; ESTROGEN RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGESTERONE RECEPTOR; PROTEIN; PROTEIN ARID1A; PROTEIN P53; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE ALPHA; POLE PROTEIN, HUMAN; POLY ADP RIBOSE BINDING PROTEIN; TUMOR MARKER;

EID: 84982149288     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-15-2878     Document Type: Article
Times cited : (613)

References (33)
  • 2
    • 33845229580 scopus 로고    scopus 로고
    • Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer
    • Creasman WT, Odicino F, Maisonneuve P, Quinn MA, Beller U, Benedet JL, et al. Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 2006;95 Suppl 1:S105-43.
    • (2006) Int J Gynaecol Obstet , vol.95 , pp. S105-S143
    • Creasman, W.T.1    Odicino, F.2    Maisonneuve, P.3    Quinn, M.A.4    Beller, U.5    Benedet, J.L.6
  • 3
    • 84869016236 scopus 로고    scopus 로고
    • Adjuvant radiotherapy for stage I endometrial cancer: An updated Cochrane systematic review and meta-analysis
    • Kong A, Johnson N, Kitchener HC, Lawrie TA. Adjuvant radiotherapy for stage I endometrial cancer: an updated Cochrane systematic review and meta-analysis. J Natl Cancer Inst 2012;104:1625-34.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 1625-1634
    • Kong, A.1    Johnson, N.2    Kitchener, H.C.3    Lawrie, T.A.4
  • 4
    • 18144432776 scopus 로고    scopus 로고
    • Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: Multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma
    • Creutzberg CL, van Putten WL, Koper PC, Lybeert ML, Jobsen JJ, Warlam-Rodenhuis CC, et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 2000;355:1404-11.
    • (2000) Lancet , vol.355 , pp. 1404-1411
    • Creutzberg, C.L.1    Van Putten, W.L.2    Koper, P.C.3    Lybeert, M.L.4    Jobsen, J.J.5    Warlam-Rodenhuis, C.C.6
  • 5
    • 1342321840 scopus 로고    scopus 로고
    • A phase III trialof surgery with orwithout adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: A Gynecologic Oncology Group study
    • Keys HM, Roberts JA, Brunetto VL, Zaino RJ, Spirtos NM, Bloss JD, et al. A phase III trialof surgery with orwithout adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 2004;92:744-51.
    • (2004) Gynecol Oncol , vol.92 , pp. 744-751
    • Keys, H.M.1    Roberts, J.A.2    Brunetto, V.L.3    Zaino, R.J.4    Spirtos, N.M.5    Bloss, J.D.6
  • 6
    • 84885354186 scopus 로고    scopus 로고
    • Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Colombo N, Preti E, Landoni F, Carinelli S, Colombo A, Marini C, et al. Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;24 Suppl 6:vi33-8.
    • (2013) Ann Oncol , vol.24 , pp. vi33-vi38
    • Colombo, N.1    Preti, E.2    Landoni, F.3    Carinelli, S.4    Colombo, A.5    Marini, C.6
  • 7
    • 77649130174 scopus 로고    scopus 로고
    • Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial
    • Nout RA, Smit VT, Putter H, Jurgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2) :an open-label, non-inferiority, randomised trial. Lancet 2010;375:816-23.
    • (2010) Lancet , vol.375 , pp. 816-823
    • Nout, R.A.1    Smit, V.T.2    Putter, H.3    Jurgenliemk-Schulz, I.M.4    Jobsen, J.J.5    Lutgens, L.C.6
  • 8
    • 84864330983 scopus 로고    scopus 로고
    • Markers for individualised therapy in endometrial carcinoma
    • Salvesen HB, Haldorsen IS, Trovik J. Markers for individualised therapy in endometrial carcinoma. Lancet Oncol 2012;13:e353-61.
    • (2012) Lancet Oncol , vol.13 , pp. e353-e361
    • Salvesen, H.B.1    Haldorsen, I.S.2    Trovik, J.3
  • 9
    • 84901423954 scopus 로고    scopus 로고
    • Classification of endometrial carcinoma: More than two types
    • Murali R, Soslow RA, Weigelt B. Classification of endometrial carcinoma: more than two types. Lancet Oncol 2014;15:e268-78.
    • (2014) Lancet Oncol , vol.15 , pp. e268-e278
    • Murali, R.1    Soslow, R.A.2    Weigelt, B.3
  • 11
    • 84930179410 scopus 로고    scopus 로고
    • Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative
    • Stelloo E, Bosse T, Nout RA, MacKay HJ, Church DN, Nijman HW, et al. Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative. Mod Pathol 2015;28:836-44.
    • (2015) Mod Pathol , vol.28 , pp. 836-844
    • Stelloo, E.1    Bosse, T.2    Nout, R.A.3    MacKay, H.J.4    Church, D.N.5    Nijman, H.W.6
  • 13
    • 84938740095 scopus 로고    scopus 로고
    • Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer - A pooled analysis of PORTEC 1 and 2 trials
    • Bosse T, Peters EE, Creutzberg CL, Jurgenliemk-Schulz IM, Jobsen JJ, Mens JW, et al. Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer - a pooled analysis of PORTEC 1 and 2 trials. Eur J Cancer 2015;51:1742-50.
    • (2015) Eur J Cancer , vol.51 , pp. 1742-1750
    • Bosse, T.1    Peters, E.E.2    Creutzberg, C.L.3    Jurgenliemk-Schulz, I.M.4    Jobsen, J.J.5    Mens, J.W.6
  • 15
    • 84899640423 scopus 로고    scopus 로고
    • High concordance of molecular tumor alterations between pre-operative curettage and hysterectomy specimens in patients with endometrial carcinoma
    • Stelloo E, Nout RA, Naves LC, Ter Haar NT, Creutzberg CL, Smit VT, et al. High concordance of molecular tumor alterations between pre-operative curettage and hysterectomy specimens in patients with endometrial carcinoma. Gynecol Oncol 2014;133:197-204.
    • (2014) Gynecol Oncol , vol.133 , pp. 197-204
    • Stelloo, E.1    Nout, R.A.2    Naves, L.C.3    Ter Haar, N.T.4    Creutzberg, C.L.5    Smit, V.T.6
  • 16
    • 84933279640 scopus 로고    scopus 로고
    • Detection of DNA mismatch repair (MMR) deficiencies by immunohistochemistry can effectively diagnose the microsatellite instability (MSI) phenotype in endometrial carcinomas
    • McConechy MK, Talhouk A, Li-Chang HH, Leung S, Huntsman DG, Gilks CB, et al. Detection of DNA mismatch repair (MMR) deficiencies by immunohistochemistry can effectively diagnose the microsatellite instability (MSI) phenotype in endometrial carcinomas. Gynecol Oncol 2015;137:306-10.
    • (2015) Gynecol Oncol , vol.137 , pp. 306-310
    • McConechy, M.K.1    Talhouk, A.2    Li-Chang, H.H.3    Leung, S.4    Huntsman, D.G.5    Gilks, C.B.6
  • 18
    • 84907430202 scopus 로고    scopus 로고
    • L1 cell adhesion molecule is a strong predictor for distant recurrence and overall survivalin early stage endometrial cancer: Pooled PORTEC trial results
    • Bosse T, Nout RA, Stelloo E, Dreef E, Nijman HW, Jurgenliemk-Schulz IM, et al. L1 cell adhesion molecule is a strong predictor for distant recurrence and overall survivalin early stage endometrial cancer: pooled PORTEC trial results. Eur J Cancer 2014;50:2602-10.
    • (2014) Eur J Cancer , vol.50 , pp. 2602-2610
    • Bosse, T.1    Nout, R.A.2    Stelloo, E.3    Dreef, E.4    Nijman, H.W.5    Jurgenliemk-Schulz, I.M.6
  • 19
  • 21
    • 84942285381 scopus 로고    scopus 로고
    • Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1
    • Howitt BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S, et al. Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1. JAMA Oncol 2015;1:1319-23.
    • (2015) JAMA Oncol , vol.1 , pp. 1319-1323
    • Howitt, B.E.1    Shukla, S.A.2    Sholl, L.M.3    Ritterhouse, L.L.4    Watkins, J.C.5    Rodig, S.6
  • 22
    • 84909619822 scopus 로고    scopus 로고
    • Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma
    • Liu Y, Patel L, Mills GB, Lu KH, Sood AK, Ding L, et al. Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma. J Natl Cancer Inst 2014;106.
    • (2014) J Natl Cancer Inst , pp. 106
    • Liu, Y.1    Patel, L.2    Mills, G.B.3    Lu, K.H.4    Sood, A.K.5    Ding, L.6
  • 23
    • 84884161920 scopus 로고    scopus 로고
    • Mismatch repair status and clinical outcome in endometrial cancer: A systematic review and meta-analysis
    • Diaz-Padilla I, Romero N, Amir E, Matias-Guiu X, Vilar E, Muggia F, et al. Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis. Crit Rev Oncol Hematol 2013;88:154-67.
    • (2013) Crit Rev Oncol Hematol , vol.88 , pp. 154-167
    • Diaz-Padilla, I.1    Romero, N.2    Amir, E.3    Matias-Guiu, X.4    Vilar, E.5    Muggia, F.6
  • 24
    • 84925615834 scopus 로고    scopus 로고
    • Differential DNA mismatch repair underlies mutation rate variation across the human genome
    • Supek F, Lehner B. Differential DNA mismatch repair underlies mutation rate variation across the human genome. Nature 2015;521:81-4.
    • (2015) Nature , vol.521 , pp. 81-84
    • Supek, F.1    Lehner, B.2
  • 25
    • 84919743846 scopus 로고    scopus 로고
    • Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication
    • Shinbrot E, Henninger EE, Weinhold N, Covington KR, Goksenin AY, Schultz N, et al. Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication. Genome Res 2014;24:1740-50.
    • (2014) Genome Res , vol.24 , pp. 1740-1750
    • Shinbrot, E.1    Henninger, E.E.2    Weinhold, N.3    Covington, K.R.4    Goksenin, A.Y.5    Schultz, N.6
  • 26
    • 84857549430 scopus 로고    scopus 로고
    • FGFR2 point mutations in 466 endometrioid endometrial tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features
    • Byron SA, Gartside M, Powell MA, Wellens CL, Gao F, Mutch DG, et al. FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features. PLoS One 2012;7:e30801.
    • (2012) PLoS One , vol.7 , pp. e30801
    • Byron, S.A.1    Gartside, M.2    Powell, M.A.3    Wellens, C.L.4    Gao, F.5    Mutch, D.G.6
  • 27
    • 84885183578 scopus 로고    scopus 로고
    • Hormone receptor lossin endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial
    • Trovik J, Wik E, Werner HM, Krakstad C, Helland H, Vandenput I, et al. Hormone receptor lossin endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial. Eur J Cancer 2013;49:3431-41.
    • (2013) Eur J Cancer , vol.49 , pp. 3431-3441
    • Trovik, J.1    Wik, E.2    Werner, H.M.3    Krakstad, C.4    Helland, H.5    Vandenput, I.6
  • 28
    • 77949801978 scopus 로고    scopus 로고
    • Up-regulation of L1CAM is linked to loss of hormone receptors and E-cadherin in aggressive subtypes of endometrial carcinomas
    • Huszar M, Pfeifer M, Schirmer U, Kiefel H, Konecny GE, Ben-Arie A, et al. Up-regulation of L1CAM is linked to loss of hormone receptors and E-cadherin in aggressive subtypes of endometrial carcinomas. J Pathol 2010;220:551-61.
    • (2010) J Pathol , vol.220 , pp. 551-561
    • Huszar, M.1    Pfeifer, M.2    Schirmer, U.3    Kiefel, H.4    Konecny, G.E.5    Ben-Arie, A.6
  • 29
    • 25844483800 scopus 로고    scopus 로고
    • Postoperative radiotherapy for Stage 1 endometrial carcinoma: Long-term outcome of the randomized PORTEC trial with central pathology review
    • Scholten AN, van Putten WL, Beerman H, Smit VT, Koper PC, Lybeert ML, et al. Postoperative radiotherapy for Stage 1 endometrial carcinoma: long-term outcome of the randomized PORTEC trial with central pathology review. Int J Radiat Oncol Biol Phys 2005;63:834-8.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 834-838
    • Scholten, A.N.1    Van Putten, W.L.2    Beerman, H.3    Smit, V.T.4    Koper, P.C.5    Lybeert, M.L.6
  • 30
    • 0041622779 scopus 로고    scopus 로고
    • Slide review in gynecologic oncology ensures completeness of reporting and diagnostic accuracy
    • Khalifa MA, Dodge J, Covens A, Osborne R, Ackerman I. Slide review in gynecologic oncology ensures completeness of reporting and diagnostic accuracy. Gynecol Oncol 2003;90:425-30.
    • (2003) Gynecol Oncol , vol.90 , pp. 425-430
    • Khalifa, M.A.1    Dodge, J.2    Covens, A.3    Osborne, R.4    Ackerman, I.5
  • 31
    • 0033863946 scopus 로고    scopus 로고
    • A binary architectural grading system for uterine endometrial endometrioid carcinoma has superior reproducibility compared with FIGO grading and identifies subsets of advance-stage tumors with favorable and unfavorable prognosis
    • Lax SF, Kurman RJ, Pizer ES, Wu L, Ronnett BM. A binary architectural grading system for uterine endometrial endometrioid carcinoma has superior reproducibility compared with FIGO grading and identifies subsets of advance-stage tumors with favorable and unfavorable prognosis. Am J Surg Pathol 2000;24:1201-8.
    • (2000) Am J Surg Pathol , vol.24 , pp. 1201-1208
    • Lax, S.F.1    Kurman, R.J.2    Pizer, E.S.3    Wu, L.4    Ronnett, B.M.5
  • 32
    • 84914674808 scopus 로고    scopus 로고
    • Grading uterine endometrioid carcinoma: A proposal that binary is best
    • Conlon N, Leitao MMJr, Abu-Rustum NR, Soslow RA. Grading uterine endometrioid carcinoma: a proposal that binary is best. Am J Surg Pathol 2014;38:1583-7.
    • (2014) Am J Surg Pathol , vol.38 , pp. 1583-1587
    • Conlon, N.1    Leitao, M.M.2    Abu-Rustum, N.R.3    Soslow, R.A.4
  • 33
    • 14644398578 scopus 로고    scopus 로고
    • Description of a novel system for grading of endometrial carcinoma and comparison with existing grading systems
    • Alkushi A, Abdul-Rahman ZH, Lim P, Schulzer M, Coldman A, Kalloger SE, et al. Description of a novel system for grading of endometrial carcinoma and comparison with existing grading systems. Am J Surg Pathol 2005;29:295-304.
    • (2005) Am J Surg Pathol , vol.29 , pp. 295-304
    • Alkushi, A.1    Abdul-Rahman, Z.H.2    Lim, P.3    Schulzer, M.4    Coldman, A.5    Kalloger, S.E.6


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