-
1
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J. A., K. J. Pearson, N. L. Price, H. A. Jamieson, C. Lerin, A. Kalra, et al. 2006. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337–342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
-
2
-
-
84883330125
-
Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats
-
Beaudoin, M. S., L. A. Snook, A. M. Arkell, J. A. Simpson, G. P. Holloway, and D. C. Wright. 2013. Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 305:R542–R551.
-
(2013)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.305
, pp. R542-R551
-
-
Beaudoin, M.S.1
Snook, L.A.2
Arkell, A.M.3
Simpson, J.A.4
Holloway, G.P.5
Wright, D.C.6
-
3
-
-
33644699965
-
The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects
-
Bruce, C. R., V. A. Mertz, G. J. Heigenhauser, and D. J. Dyck. 2005. The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects. Diabetes 54:3154–3160.
-
(2005)
Diabetes
, vol.54
, pp. 3154-3160
-
-
Bruce, C.R.1
Mertz, V.A.2
Heigenhauser, G.J.3
Dyck, D.J.4
-
4
-
-
84873947174
-
Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity
-
Bruckbauer, A., and M. B. Zemel. 2013. Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity. Diabetes Metab. Syndr. Obes. 6:93–102.
-
(2013)
Diabetes Metab. Syndr. Obes.
, vol.6
, pp. 93-102
-
-
Bruckbauer, A.1
Zemel, M.B.2
-
5
-
-
0036097556
-
Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects
-
Ciaraldi, T. P., A. P. Kong, N. V. Chu, D. D. Kim, S. Baxi, M. Loviscach, et al. 2002. Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. Diabetes 51:30–36.
-
(2002)
Diabetes
, vol.51
, pp. 30-36
-
-
Ciaraldi, T.P.1
Kong, A.P.2
Chu, N.V.3
Kim, D.D.4
Baxi, S.5
Loviscach, M.6
-
6
-
-
0033578476
-
Pharmacologic therapy for type 2 diabetes mellitus
-
DeFronzo, R. A. 1999. Pharmacologic therapy for type 2 diabetes mellitus. Ann. Intern. Med. 131:281–303.
-
(1999)
Ann. Intern. Med.
, vol.131
, pp. 281-303
-
-
DeFronzo, R.A.1
-
7
-
-
84982111580
-
Safety of synthetic trans-resveratrol as a novel food pursuant to Regulation (EC) No 258/97
-
EFSA Panel on Dietetic Products NaA. 2016. Safety of synthetic trans-resveratrol as a novel food pursuant to Regulation (EC) No 258/97. EFSA J. 14:4368.
-
(2016)
EFSA J.
, vol.14
, pp. 4368
-
-
-
8
-
-
84940609721
-
The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study
-
Faghihzadeh, F., P. Adibi, and A. Hekmatdoost. 2015. The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study. Br. J. Nutr. 114:796–803.
-
(2015)
Br. J. Nutr.
, vol.114
, pp. 796-803
-
-
Faghihzadeh, F.1
Adibi, P.2
Hekmatdoost, A.3
-
9
-
-
84941730257
-
New nordic diet-induced weight loss is accompanied by changes in metabolism and AMPK signaling in adipose tissue
-
Fritzen, A. M., A. M. Lundsgaard, A. B. Jordy, S. K. Poulsen, S. Stender, H. Pilegaard, et al. 2015. New nordic diet-induced weight loss is accompanied by changes in metabolism and AMPK signaling in adipose tissue. J. Clin. Endocrinol. Metab. 100:3509–3519.
-
(2015)
J. Clin. Endocrinol. Metab.
, vol.100
, pp. 3509-3519
-
-
Fritzen, A.M.1
Lundsgaard, A.M.2
Jordy, A.B.3
Poulsen, S.K.4
Stender, S.5
Pilegaard, H.6
-
10
-
-
0036430411
-
Effect of metformin on adipose tissue resistin expression in db/db mice
-
Fujita, H., H. Fujishima, T. Morii, J. Koshimura, T. Narita, M. Kakei, et al. 2002. Effect of metformin on adipose tissue resistin expression in db/db mice. Biochem. Biophys. Res. Commun. 298:345–349.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.298
, pp. 345-349
-
-
Fujita, H.1
Fujishima, H.2
Morii, T.3
Koshimura, J.4
Narita, T.5
Kakei, M.6
-
11
-
-
77954214952
-
Protective effect of metformin in CD1 mice placed on a high carbohydrate-high fat diet
-
Hou, M., N. Venier, L. Sugar, M. Musquera, M. Pollak, A. Kiss, et al. 2010. Protective effect of metformin in CD1 mice placed on a high carbohydrate-high fat diet. Biochem. Biophys. Res. Commun. 397:537–542.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.397
, pp. 537-542
-
-
Hou, M.1
Venier, N.2
Sugar, L.3
Musquera, M.4
Pollak, M.5
Kiss, A.6
-
12
-
-
0033673203
-
Mechanism by which metformin reduces glucose production in type 2 diabetes
-
Hundal, R. S., M. Krssak, S. Dufour, D. Laurent, V. Lebon, V. Chandramouli, et al. 2000. Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes 49:2063–2069.
-
(2000)
Diabetes
, vol.49
, pp. 2063-2069
-
-
Hundal, R.S.1
Krssak, M.2
Dufour, S.3
Laurent, D.4
Lebon, V.5
Chandramouli, V.6
-
13
-
-
0032568257
-
Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus
-
Inzucchi, S. E., D. G. Maggs, G. R. Spollett, S. L. Page, F. S. Rife, V. Walton, et al. 1998. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N. Engl. J. Med. 338:867–872.
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 867-872
-
-
Inzucchi, S.E.1
Maggs, D.G.2
Spollett, G.R.3
Page, S.L.4
Rife, F.S.5
Walton, V.6
-
14
-
-
36849085935
-
Essential role of mitochondrial function in adiponectin synthesis in adipocytes
-
Koh, E. H., J. Y. Park, H. S. Park, M. J. Jeon, J. W. Ryu, M. Kim, et al. 2007. Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes 56:2973–2981.
-
(2007)
Diabetes
, vol.56
, pp. 2973-2981
-
-
Koh, E.H.1
Park, J.Y.2
Park, H.S.3
Jeon, M.J.4
Ryu, J.W.5
Kim, M.6
-
15
-
-
84872311894
-
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
-
Kristensen, J. M., S. Larsen, J. W. Helge, F. Dela, and J. F. Wojtaszewski. 2013. Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS ONE 8:e53533.
-
(2013)
PLoS ONE
, vol.8
-
-
Kristensen, J.M.1
Larsen, S.2
Helge, J.W.3
Dela, F.4
Wojtaszewski, J.F.5
-
16
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
Lagouge, M., C. Argmann, Z. Gerhart-Hines, H. Meziane, C. Lerin, F. Daussin, et al. 2006. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127:1109–1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
-
17
-
-
80053406579
-
Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance
-
Lee, Y. S., P. Li, J. Y. Huh, I. J. Hwang, M. Lu, J. I. Kim, et al. 2011. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes 60:2474–2483.
-
(2011)
Diabetes
, vol.60
, pp. 2474-2483
-
-
Lee, Y.S.1
Li, P.2
Huh, J.Y.3
Hwang, I.J.4
Lu, M.5
Kim, J.I.6
-
18
-
-
0027994088
-
Markers of mouse macrophage development detected by monoclonal antibodies
-
Leenen, P. J., M. F. de Bruijn, J. S. Voerman, P. A. Campbell, and W. van Ewijk. 1994. Markers of mouse macrophage development detected by monoclonal antibodies. J. Immunol. Methods 174:5–19.
-
(1994)
J. Immunol. Methods
, vol.174
, pp. 5-19
-
-
Leenen, P.J.1
de Bruijn, M.F.2
Voerman, J.S.3
Campbell, P.A.4
van Ewijk, W.5
-
19
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402–408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
20
-
-
31844437335
-
Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects
-
Luna, V., L. Casauban, M. P. Sajan, J. Gomez-Daspet, J. L. Powe, A. Miura, et al. 2006. Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO4)3 in muscle of diabetic subjects. Diabetologia 49:375–382.
-
(2006)
Diabetologia
, vol.49
, pp. 375-382
-
-
Luna, V.1
Casauban, L.2
Sajan, M.P.3
Gomez-Daspet, J.4
Powe, J.L.5
Miura, A.6
-
21
-
-
84941778684
-
Adipose tissue insulin action and IL-6 signaling following exercise in obese mice
-
MacPherson, R. E., J. S. Huber, S. Frendo-Cumbo, J. A. Simpson, and D. C. Wright. 2015. Adipose tissue insulin action and IL-6 signaling following exercise in obese mice. Med. Sci. Sports Exerc. 2034–2042.
-
(2015)
Med. Sci. Sports Exerc.
, vol.2034-2042
-
-
MacPherson, R.E.1
Huber, J.S.2
Frendo-Cumbo, S.3
Simpson, J.A.4
Wright, D.C.5
-
22
-
-
84976630766
-
Sarcolipin knockout mice fed a high fat diet exhibit altered indices of adipose tissue inflammation and remodelling
-
MacPherson, R. E., D. Gamu, S. Frendo-Cumbo, L. Castellani, F. Kwon, A. R. Tupling, et al. 2016. Sarcolipin knockout mice fed a high fat diet exhibit altered indices of adipose tissue inflammation and remodelling. Obesity (Silver Spring) 24:1499–1505.
-
(2016)
Obesity (Silver Spring)
, vol.24
, pp. 1499-1505
-
-
MacPherson, R.E.1
Gamu, D.2
Frendo-Cumbo, S.3
Castellani, L.4
Kwon, F.5
Tupling, A.R.6
-
23
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers, C. D., and D. Loncar. 2006. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 3:e442.
-
(2006)
PLoS Med.
, vol.3
-
-
Mathers, C.D.1
Loncar, D.2
-
24
-
-
0034833667
-
Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone
-
Miyazaki, Y., A. Mahankali, M. Matsuda, L. Glass, S. Mahankali, E. Ferrannini, et al. 2001. Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. Diabetes Care 24:710–719.
-
(2001)
Diabetes Care
, vol.24
, pp. 710-719
-
-
Miyazaki, Y.1
Mahankali, A.2
Matsuda, M.3
Glass, L.4
Mahankali, S.5
Ferrannini, E.6
-
25
-
-
0036072223
-
Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients
-
Miyazaki, Y., A. Mahankali, M. Matsuda, S. Mahankali, J. Hardies, K. Cusi, et al. 2002. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J. Clin. Endocrinol. Metab. 87:2784–2791.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2784-2791
-
-
Miyazaki, Y.1
Mahankali, A.2
Matsuda, M.3
Mahankali, S.4
Hardies, J.5
Cusi, K.6
-
26
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi, N., M. F. Hirshman, J. Nygren, M. Svanfeldt, P. Bavenholm, O. Rooyackers, et al. 2002. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 51:2074–2081.
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
-
27
-
-
33646346627
-
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
-
Nawrocki, A. R., M. W. Rajala, E. Tomas, U. B. Pajvani, A. K. Saha, M. E. Trumbauer, et al. 2006. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J. Biol. Chem. 281:2654–2660.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2654-2660
-
-
Nawrocki, A.R.1
Rajala, M.W.2
Tomas, E.3
Pajvani, U.B.4
Saha, A.K.5
Trumbauer, M.E.6
-
28
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen, S. E., and K. Wolski. 2007. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med. 356:2457–2471.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
29
-
-
84892820006
-
Potential of resveratrol in the treatment of heart failure
-
Raj, P., X. L. Louis, S. J. Thandapilly, A. Movahed, S. Zieroth, and T. Netticadan. 2014. Potential of resveratrol in the treatment of heart failure. Life Sci. 95:63–71.
-
(2014)
Life Sci.
, vol.95
, pp. 63-71
-
-
Raj, P.1
Louis, X.L.2
Thandapilly, S.J.3
Movahed, A.4
Zieroth, S.5
Netticadan, T.6
-
30
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, et al. 1985. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150:76–85.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
-
31
-
-
35148856230
-
Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes
-
Stafford, J. M., and T. Elasy. 2007. Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes. Vasc. Health Risk Manag. 3:503–510.
-
(2007)
Vasc. Health Risk Manag.
, vol.3
, pp. 503-510
-
-
Stafford, J.M.1
Elasy, T.2
-
32
-
-
84937809888
-
Therapeutic potential of resveratrol in heart failure
-
Sung, M. M., and J. R. Dyck. 2015. Therapeutic potential of resveratrol in heart failure. Ann. N. Y. Acad. Sci. 1348:32–45.
-
(2015)
Ann. N. Y. Acad. Sci.
, vol.1348
, pp. 32-45
-
-
Sung, M.M.1
Dyck, J.R.2
-
33
-
-
84941299736
-
Resveratrol and SRT1720 elicit differential effects in metabolic organs and modulate systemic parameters independently of skeletal muscle peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha)
-
Svensson, K., S. Schnyder, V. Albert, B. Cardel, L. Quagliata, L. M. Terracciano, et al. 2015. Resveratrol and SRT1720 elicit differential effects in metabolic organs and modulate systemic parameters independently of skeletal muscle peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha). J. Biol. Chem. 290:16059–16076.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 16059-16076
-
-
Svensson, K.1
Schnyder, S.2
Albert, V.3
Cardel, B.4
Quagliata, L.5
Terracciano, L.M.6
-
34
-
-
80455143206
-
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
-
Timmers, S., E. Konings, L. Bilet, R. H. Houtkooper, T. van de Weijer, G. H. Goossens, et al. 2011. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 14:612–622.
-
(2011)
Cell Metab.
, vol.14
, pp. 612-622
-
-
Timmers, S.1
Konings, E.2
Bilet, L.3
Houtkooper, R.H.4
van de Weijer, T.5
Goossens, G.H.6
-
35
-
-
84902603532
-
Thiazolidinediones and associated risk of Bladder Cancer: a Systematic Review and Meta-analysis
-
Turner, R. M., C. S. Kwok, C. Chen-Turner, C. A. Maduakor, S. Singh, and Y. K. Loke. 2014. Thiazolidinediones and associated risk of Bladder Cancer: a Systematic Review and Meta-analysis. Br. J. Clin. Pharmacol. 78:258–273.
-
(2014)
Br. J. Clin. Pharmacol.
, vol.78
, pp. 258-273
-
-
Turner, R.M.1
Kwok, C.S.2
Chen-Turner, C.3
Maduakor, C.A.4
Singh, S.5
Loke, Y.K.6
-
36
-
-
78650929972
-
Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L
-
Wang, A., M. Liu, X. Liu, L. Q. Dong, R. D. Glickman, T. J. Slaga, et al. 2011. Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L. J. Biol. Chem. 286:60–66.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 60-66
-
-
Wang, A.1
Liu, M.2
Liu, X.3
Dong, L.Q.4
Glickman, R.D.5
Slaga, T.J.6
-
37
-
-
84896105051
-
Short-term resveratrol exposure causes in vitro and in vivo growth inhibition and apoptosis of bladder cancer cells
-
Wu, M. L., H. Li, L. J. Yu, X. Y. Chen, Q. Y. Kong, X. Song, et al. 2014. Short-term resveratrol exposure causes in vitro and in vivo growth inhibition and apoptosis of bladder cancer cells. PLoS ONE 9:e89806.
-
(2014)
PLoS ONE
, vol.9
-
-
Wu, M.L.1
Li, H.2
Yu, L.J.3
Chen, X.Y.4
Kong, Q.Y.5
Song, X.6
-
38
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H., G. T. Barnes, Q. Yang, G. Tan, D. Yang, C. J. Chou, et al. 2003. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112:1821–1830.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
-
39
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi, T., J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, et al. 2002. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8:1288–1295.
-
(2002)
Nat. Med.
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
-
40
-
-
84871445402
-
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance
-
Yoshino, J., C. Conte, L. Fontana, B. Mittendorfer, S. Imai, K. B. Schechtman, et al. 2012. Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab. 16:658–664.
-
(2012)
Cell Metab.
, vol.16
, pp. 658-664
-
-
Yoshino, J.1
Conte, C.2
Fontana, L.3
Mittendorfer, B.4
Imai, S.5
Schechtman, K.B.6
|