메뉴 건너뛰기




Volumn 22, Issue 9, 2016, Pages 994-1001

Identification of a major epitope by anti-interferon-γ autoantibodies in patients with mycobacterial disease

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIMYCOBACTERIAL AGENT; AUTOANTIBODY; EPITOPE ERASED VARIANT OF INTERFERON GAMMA; FUNGAL PROTEIN; GAMMA INTERFERON 1 131; GAMMA INTERFERON ANTIBODY; GAMMA INTERFERON DERIVATIVE; GAMMA INTERFERON RECEPTOR; HLA DQB1 ANTIGEN; HLA DRB1 ANTIGEN; INTERLEUKIN 12P40; NEUTRALIZING ANTIBODY; NOC2 PROTEIN; RECOMBINANT GAMMA INTERFERON; RECOMBINANT PROTEIN; STAT1 PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; AUTOANTIGEN; EPITOPE; GAMMA INTERFERON; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; INTERFERON RECEPTOR;

EID: 84982102692     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4158     Document Type: Article
Times cited : (82)

References (46)
  • 1
    • 1542542689 scopus 로고    scopus 로고
    • Autoantibodies to interferon-γ in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity
    • Döffinger, R. et al. Autoantibodies to interferon-γ in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clin. Infect. Dis. 38, e10-e14 (2004).
    • (2004) Clin. Infect. Dis. , vol.38 , pp. e10-e14
    • Döffinger, R.1
  • 2
    • 9144235409 scopus 로고    scopus 로고
    • Naturally occurring anti-IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans
    • Höflich, C. et al. Naturally occurring anti-IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood 103, 673-675 (2004).
    • (2004) Blood , vol.103 , pp. 673-675
    • Höflich, C.1
  • 3
    • 24644486557 scopus 로고    scopus 로고
    • Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ
    • Kampmann, B. et al. Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-γ. J. Clin. Invest. 115, 2480-2488 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 2480-2488
    • Kampmann, B.1
  • 4
    • 25444487466 scopus 로고    scopus 로고
    • Anti-IFN-γ autoantibodies in disseminated nontuberculous mycobacterial infections
    • Patel, S.Y. et al. Anti-IFN-γ autoantibodies in disseminated nontuberculous mycobacterial infections. J. Immunol. 175, 4769-4776 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 4769-4776
    • Patel, S.Y.1
  • 5
    • 40449106777 scopus 로고    scopus 로고
    • Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6
    • Puel, A. et al. Recurrent staphylococcal cellulitis and subcutaneous abscesses in a child with autoantibodies against IL-6. J. Immunol. 180, 647-654 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 647-654
    • Puel, A.1
  • 6
    • 77149124612 scopus 로고    scopus 로고
    • Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
    • Puel, A. et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J. Exp. Med. 207, 291-297 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 291-297
    • Puel, A.1
  • 7
    • 84865300679 scopus 로고    scopus 로고
    • Adult-onset immunodeficiency in Thailand and Taiwan
    • Browne, S.K. et al. Adult-onset immunodeficiency in Thailand and Taiwan. N. Engl. J. Med. 367, 725-734 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 725-734
    • Browne, S.K.1
  • 8
    • 84874436360 scopus 로고    scopus 로고
    • Anti-IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1∗16:02 and HLA-DQB1∗05:02 and the reactivation of latent varicella-zoster virus infection
    • Chi, C.Y. et al. Anti-IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1∗16:02 and HLA-DQB1∗05:02 and the reactivation of latent varicella-zoster virus infection. Blood 121, 1357-1366 (2013).
    • (2013) Blood , vol.121 , pp. 1357-1366
    • Chi, C.Y.1
  • 9
    • 84875976539 scopus 로고    scopus 로고
    • Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis
    • Rosen, L.B. et al. Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J. Immunol. 190, 3959-3966 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 3959-3966
    • Rosen, L.B.1
  • 10
    • 84875661798 scopus 로고    scopus 로고
    • Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of mendelian susceptibility to mycobacterial disease (MSMD) lacking bacille Calmette-Guerin (BCG)-induced diseases
    • Lee, W.I. et al. Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of mendelian susceptibility to mycobacterial disease (MSMD) lacking bacille Calmette-Guerin (BCG)-induced diseases. Immunobiology 218, 762-771 (2013).
    • (2013) Immunobiology , vol.218 , pp. 762-771
    • Lee, W.I.1
  • 11
    • 84897106065 scopus 로고    scopus 로고
    • Anticytokine autoantibody-associated immunodeficiency
    • Browne, S.K. Anticytokine autoantibody-associated immunodeficiency. Annu. Rev. Immunol. 32, 635-657 (2014).
    • (2014) Annu. Rev. Immunol. , vol.32 , pp. 635-657
    • Browne, S.K.1
  • 12
    • 84926620785 scopus 로고    scopus 로고
    • Nocardia-induced granulocyte macrophage colony-stimulating factor is neutralized by autoantibodies in disseminated/extrapulmonary nocardiosis
    • Rosen, L.B. et al. Nocardia-induced granulocyte macrophage colony-stimulating factor is neutralized by autoantibodies in disseminated/extrapulmonary nocardiosis. Clin. Infect. Dis. 60, 1017-1025 (2015).
    • (2015) Clin. Infect. Dis. , vol.60 , pp. 1017-1025
    • Rosen, L.B.1
  • 13
    • 84976426602 scopus 로고    scopus 로고
    • Clinical manifestations, course, and outcome of patients with neutralizing anti-interferon-γ autoantibodies and disseminated nontuberculous mycobacterial infections
    • Chi, C.Y. et al. Clinical manifestations, course, and outcome of patients with neutralizing anti-interferon-γ autoantibodies and disseminated nontuberculous mycobacterial infections. Medicine (Baltimore) 95, e3927 (2016).
    • (2016) Medicine (Baltimore) , vol.95
    • Chi, C.Y.1
  • 14
    • 0028869497 scopus 로고
    • Familial disseminated atypical mycobacterial infection in childhood: A human mycobacterial susceptibility gene?
    • Levin, M. et al. Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene? Lancet 345, 79-83 (1995).
    • (1995) Lancet , vol.345 , pp. 79-83
    • Levin, M.1
  • 15
    • 0029838301 scopus 로고    scopus 로고
    • Idiopathic disseminated bacillus Calmette-Guérin infection: A French national retrospective study
    • Casanova, J.L. et al. Idiopathic disseminated bacillus Calmette-Guérin infection: a French national retrospective study. Pediatrics 98, 774-778 (1996).
    • (1996) Pediatrics , vol.98 , pp. 774-778
    • Casanova, J.L.1
  • 16
    • 84920146763 scopus 로고    scopus 로고
    • Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity
    • Bustamante, J., Boisson-Dupuis, S., Abel, L. & Casanova, J.L. Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity. Semin. Immunol. 26, 454-470 (2014).
    • (2014) Semin. Immunol. , vol.26 , pp. 454-470
    • Bustamante, J.1    Boisson-Dupuis, S.2    Abel, L.3    Casanova, J.L.4
  • 17
    • 84874445207 scopus 로고    scopus 로고
    • Autoantibodies against cytokines: Back to human genetics
    • Puel, A. & Casanova, J.L. Autoantibodies against cytokines: back to human genetics. Blood 121, 1246-1247 (2013).
    • (2013) Blood , vol.121 , pp. 1246-1247
    • Puel, A.1    Casanova, J.L.2
  • 18
    • 77950347321 scopus 로고    scopus 로고
    • Infections and autoimmunity: The multifaceted relationship
    • Sfriso, P. et al. Infections and autoimmunity: the multifaceted relationship. J. Leukoc. Biol. 87, 385-395 (2010).
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 385-395
    • Sfriso, P.1
  • 19
    • 0001219369 scopus 로고
    • Antigenic cross-reaction between host and parasite as a possible cause of pathogenicity
    • Rowley, D. & Jenkin, C.R. Antigenic cross-reaction between host and parasite as a possible cause of pathogenicity. Nature 193, 151-154 (1962).
    • (1962) Nature , vol.193 , pp. 151-154
    • Rowley, D.1    Jenkin, C.R.2
  • 21
    • 84905717047 scopus 로고    scopus 로고
    • Guillain-Barré syndrome: Pathogenesis, diagnosis, treatment and prognosis
    • van den Berg, B. et al. Guillain-Barré syndrome: pathogenesis, diagnosis, treatment and prognosis. Nat. Rev. Neurol. 10, 469-482 (2014).
    • (2014) Nat. Rev. Neurol. , vol.10 , pp. 469-482
    • Van Den Berg, B.1
  • 22
    • 53549100724 scopus 로고    scopus 로고
    • Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis
    • Kain, R. et al. Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis. Nat. Med. 14, 1088-1096 (2008).
    • (2008) Nat. Med. , vol.14 , pp. 1088-1096
    • Kain, R.1
  • 23
    • 84951310291 scopus 로고    scopus 로고
    • Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia
    • e8
    • Ku, C.L. et al. Anti-IFN-γ autoantibodies are strongly associated with HLA-DR∗15:02/16:02 and HLA-DQ∗05:01/05:02 across Southeast Asia. J. Allergy Clin. Immunol. 137, 945-948.e8 (2016).
    • (2016) J. Allergy Clin. Immunol. , vol.137 , pp. 945-948
    • Ku, C.L.1
  • 24
    • 0022249654 scopus 로고
    • Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide
    • Emini, E.A., Hughes, J.V., Perlow, D.S. & Boger, J. Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J. Virol. 55, 836-839 (1985).
    • (1985) J. Virol. , vol.55 , pp. 836-839
    • Emini, E.A.1    Hughes, J.V.2    Perlow, D.S.3    Boger, J.4
  • 25
    • 33751104704 scopus 로고    scopus 로고
    • Improved method for predicting linear B-cell epitopes
    • Larsen, J.E., Lund, O. & Nielsen, M. Improved method for predicting linear B-cell epitopes. Immunome Res. 2, 2 (2006).
    • (2006) Immunome Res. , vol.2 , pp. 2
    • Larsen, J.E.1    Lund, O.2    Nielsen, M.3
  • 26
    • 61449229355 scopus 로고    scopus 로고
    • Protein structure homology modeling using SWISS-MODEL workspace
    • Bordoli, L. et al. Protein structure homology modeling using SWISS-MODEL workspace. Nat. Protoc. 4, 1-13 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 1-13
    • Bordoli, L.1
  • 27
    • 0025730621 scopus 로고
    • Three-dimensional structure of recombinant human interferon-γ
    • Ealick, S.E. et al. Three-dimensional structure of recombinant human interferon-γ. Science 252, 698-702 (1991).
    • (1991) Science , vol.252 , pp. 698-702
    • Ealick, S.E.1
  • 28
    • 0029067876 scopus 로고
    • Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor
    • Walter, M.R. et al. Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature 376, 230-235 (1995).
    • (1995) Nature , vol.376 , pp. 230-235
    • Walter, M.R.1
  • 29
    • 0034665458 scopus 로고    scopus 로고
    • Observation of an unexpected third receptor molecule in the crystal structure of human interferon-γ receptor complex
    • Thiel, D.J. et al. Observation of an unexpected third receptor molecule in the crystal structure of human interferon-γ receptor complex. Structure 8, 927-936 (2000).
    • (2000) Structure , vol.8 , pp. 927-936
    • Thiel, D.J.1
  • 30
    • 0026093103 scopus 로고
    • The carboxyl-terminal region of human interferon gamma is important for biological activity: Mutagenic and NMR analysis
    • Lundell, D. et al. The carboxyl-terminal region of human interferon gamma is important for biological activity: mutagenic and NMR analysis. Protein Eng. 4, 335-341 (1991).
    • (1991) Protein Eng. , vol.4 , pp. 335-341
    • Lundell, D.1
  • 32
    • 0020623478 scopus 로고
    • Recombinant interferon-γ increases HLA-DR synthesis and expression
    • Basham, T.Y. & Merigan, T.C. Recombinant interferon-γ increases HLA-DR synthesis and expression. J. Immunol. 130, 1492-1494 (1983).
    • (1983) J. Immunol. , vol.130 , pp. 1492-1494
    • Basham, T.Y.1    Merigan, T.C.2
  • 33
    • 0023898834 scopus 로고
    • Evidence for a polypeptide segment at the carboxyl terminus of recombinant human gamma interferon involved in expression of biological activity
    • Seelig, G.F., Wijdenes, J., Nagabhushan, T.L. & Trotta, P.P. Evidence for a polypeptide segment at the carboxyl terminus of recombinant human gamma interferon involved in expression of biological activity. Biochemistry 27, 1981-1987 (1988).
    • (1988) Biochemistry , vol.27 , pp. 1981-1987
    • Seelig, G.F.1    Wijdenes, J.2    Nagabhushan, T.L.3    Trotta, P.P.4
  • 34
    • 84877339165 scopus 로고    scopus 로고
    • Characterization of pathogenic human monoclonal autoantibodies against GM-CSF
    • Wang, Y. et al. Characterization of pathogenic human monoclonal autoantibodies against GM-CSF. Proc. Natl. Acad. Sci. USA 110, 7832-7837 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 7832-7837
    • Wang, Y.1
  • 35
    • 84935857724 scopus 로고    scopus 로고
    • Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis
    • Piccoli, L. et al. Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis. Nat. Commun. 6, 7375 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 7375
    • Piccoli, L.1
  • 36
    • 84875500441 scopus 로고    scopus 로고
    • Performance of two Aspergillus IgG EIA assays compared with the precipitin test in chronic and allergic aspergillosis
    • Baxter, C.G. et al. Performance of two Aspergillus IgG EIA assays compared with the precipitin test in chronic and allergic aspergillosis. Clin. Microbiol. Infect. 19, E197-E204 (2013).
    • (2013) Clin. Microbiol. Infect. , vol.19 , pp. E197-E204
    • Baxter, C.G.1
  • 37
    • 33748542289 scopus 로고    scopus 로고
    • Aspergillosis: Spectrum of disease, diagnosis, and treatment
    • Barnes, P.D. & Marr, K.A. Aspergillosis: spectrum of disease, diagnosis, and treatment. Infect. Dis. Clin. North Am. 20, 545-561 (2006).
    • (2006) Infect. Dis. Clin. North Am. , vol.20 , pp. 545-561
    • Barnes, P.D.1    Marr, K.A.2
  • 38
    • 84927562663 scopus 로고    scopus 로고
    • The lung mycobiome: An emerging field of the human respiratory microbiome
    • Nguyen, L.D., Viscogliosi, E. & Delhaes, L. The lung mycobiome: an emerging field of the human respiratory microbiome. Front. Microbiol. 6, 89 (2015).
    • (2015) Front. Microbiol. , vol.6 , pp. 89
    • Nguyen, L.D.1    Viscogliosi, E.2    Delhaes, L.3
  • 39
    • 77949506518 scopus 로고    scopus 로고
    • Healthy human T-Cell Responses to Aspergillus fumigatus antigens
    • Chaudhary, N., Staab, J.F. & Marr, K.A. Healthy human T-Cell Responses to Aspergillus fumigatus antigens. PLoS One 5, e9036 (2010).
    • (2010) PLoS One , vol.5
    • Chaudhary, N.1    Staab, J.F.2    Marr, K.A.3
  • 40
    • 0031664697 scopus 로고    scopus 로고
    • Molecular mimicry and immune-mediated diseases
    • Oldstone, M.B. Molecular mimicry and immune-mediated diseases. FASEB J. 12, 1255-1265 (1998).
    • (1998) FASEB J. , vol.12 , pp. 1255-1265
    • Oldstone, M.B.1
  • 41
    • 80052861380 scopus 로고    scopus 로고
    • Global population structure of Aspergillus terreus inferred by ISSR typing reveals geographical subclustering
    • Neal, C.O. et al. Global population structure of Aspergillus terreus inferred by ISSR typing reveals geographical subclustering. BMC Microbiol. 11, 203 (2011).
    • (2011) BMC Microbiol. , vol.11 , pp. 203
    • Neal, C.O.1
  • 42
    • 84860333126 scopus 로고    scopus 로고
    • Anti-CD20 (rituximab) therapy for anti-IFN-γ autoantibody-associated nontuberculous mycobacterial infection
    • Browne, S.K. et al. Anti-CD20 (rituximab) therapy for anti-IFN-γ autoantibody-associated nontuberculous mycobacterial infection. Blood 119, 3933-3939 (2012).
    • (2012) Blood , vol.119 , pp. 3933-3939
    • Browne, S.K.1
  • 43
    • 67650496601 scopus 로고    scopus 로고
    • Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS)
    • Rao, V.K. et al. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatr. Blood Cancer 52, 847-852 (2009).
    • (2009) Pediatr. Blood Cancer , vol.52 , pp. 847-852
    • Rao, V.K.1
  • 44
    • 77954557374 scopus 로고    scopus 로고
    • Rituximab: A review of its use in chronic lymphocytic leukaemia, low-grade or follicular lymphoma and diffuse large B-cell lymphoma
    • Keating, G.M. Rituximab: a review of its use in chronic lymphocytic leukaemia, low-grade or follicular lymphoma and diffuse large B-cell lymphoma. Drugs 70, 1445-1476 (2010).
    • (2010) Drugs , vol.70 , pp. 1445-1476
    • Keating, G.M.1
  • 45
    • 79953072406 scopus 로고    scopus 로고
    • Partial recessive IFN-γR1 deficiency: Genetic, immunological and clinical features of 14 patients from 11 kindreds
    • Sologuren, I. et al. Partial recessive IFN-γR1 deficiency: genetic, immunological and clinical features of 14 patients from 11 kindreds. Hum. Mol. Genet. 20, 1509-1523 (2011).
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1509-1523
    • Sologuren, I.1
  • 46
    • 63849240274 scopus 로고    scopus 로고
    • Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen
    • Smith, K. et al. Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nat. Protoc. 4, 372-384 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 372-384
    • Smith, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.