Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of Mendelian Susceptibility to Mycobacterial Disease (MSMD) lacking Bacille Calmette-Guerin (BCG)-induced diseases

Immunobiology

Volumn 218, Issue 5, 2013, Pages 762-771

  Lee, Wen I ^a   Huang, Jing Long ^a   Wu, Ting Shu ^b   Lee, Ming Hsun ^b   Chen, I Jung ^b   Yu, Kuang Hiu ^b   Liu, Chien Ying ^b   Yang, Chih Hsun ^b   Hsieh, Meng Ying ^a   Lin, Yi Ling ^a   Shih, Ying Fan ^a   Jaing, Tang Her ^a   Huang, Shih Chiang ^b   Kuo, Tseng Tong ^b   Ku, Cheng Lung ^c  

^a CHANG GUNG CHILDREN S HOSPITAL   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Autoantibodies to IFN (AutoAbs IFN ); Bacille Calmette Guerin infection (BCGitis); IL 12 23 IFN circuit; Mendelian Susceptibility to Mycobacterial Disease (MSMD); Primary immunodeficiency diseases (PIDs)

Indexed keywords

BCG VACCINE; GAMMA INTERFERON ANTIBODY; GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR 1; GAMMA INTERFERON RECEPTOR 2; I KAPPA B KINASE ALPHA; I KAPPA B KINASE GAMMA; INHIBITORY GAMMA INTERFERON AUTOANTIBODY; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR BETA1; INTERLEUKIN 12P40; INTERLEUKIN 23; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEUTRALIZING GAMMA INTERFERON AUTOANTIBODY; PEPTIDES AND PROTEINS; PROTEIN CYBB; RECOMBINANT INTERFERON; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; ASIAN; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; CYBB GENE; ETHNIC GROUP; FEMALE; GENE; GENE MUTATION; GENE SEQUENCE; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; IRF8 GENE; LEUKEMIA CELL LINE; LYMPHADENOPATHY; MALE; MYCOBACTERIOSIS; MYCOBACTERIUM ABSCESSUS; MYCOBACTERIUM CHELONEI; MYCOBACTERIUM INTRACELLULARE AVIUM; ONSET AGE; OSTEOMYELITIS; PENICILLIOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT INFECTION; SALMONELLA ENTERICA; SALMONELLOSIS; SEPSIS; TAIWANESE; UNSPECIFIED SIDE EFFECT;

AGE OF ONSET; ANTIBODIES, NEUTRALIZING; ASIAN CONTINENTAL ANCESTRY GROUP; AUTOANTIBODIES; CHRONIC DISEASE; CYTOKINES; DIAGNOSIS, DIFFERENTIAL; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; INTERFERON-GAMMA; JURKAT CELLS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM INFECTIONS, NONTUBERCULOUS; OSTEOMYELITIS; PHENOTYPE; SALMONELLA INFECTIONS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84875661798     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.08.281     Document Type: Article

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