Assessment of HER2 status in patients with gastroesophageal adenocarcinoma treated with epirubicin-based chemotherapy: heterogeneity-related issues and prognostic implications

Gastric Cancer

Volumn 20, Issue 3, 2017, Pages 428-437

  Personeni, Nicola ^a,b   Baretti, Marina ^a   Bozzarelli, Silvia ^a   Spaggiari, Paola ^a   Rubino, Luca ^a   Tronconi, Maria Chiara ^a   Fumagalli Romario, Uberto ^a   Rosati, Riccardo ^a,d   Giordano, Laura ^a   Roncalli, Massimo ^a,b   Santoro, Armando ^a,c   Rimassa, Lorenza ^a  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c HUMANITAS UNIVERSITY   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Epirubicin; FISH; Gastroesophageal; HER2; Heterogeneity; Immunohistochemistry; Topoisomerase 2 alpha

Indexed keywords

CISPLATIN; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; FLUOROURACIL; FOLINIC ACID; GLUTATHIONE; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; DNA TOPOISOMERASE II ALPHA; ERBB2 PROTEIN, HUMAN; TUMOR ANTIGEN; TUMOR MARKER;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER PROGNOSIS; CLINICAL FEATURE; CONTINUOUS INFUSION; DISEASE FREE SURVIVAL; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS BIOPSY; ESOPHAGUS SURGERY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE AMPLIFICATION; HER2 GENE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OVERALL SURVIVAL; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PROTEIN EXPRESSION; RISK REDUCTION; SAMPLING ERROR; STOMACH ADENOCARCINOMA; STOMACH BIOPSY; STOMACH SURGERY; TOP2A GENE; ADENOCARCINOMA; AGED; ESOPHAGEAL NEOPLASMS; GENETICS; METABOLISM; MORTALITY; PATHOLOGY; PROGNOSIS; STOMACH NEOPLASMS; TREATMENT OUTCOME;

ADENOCARCINOMA; AGED; ANTIGENS, NEOPLASM; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOMARKERS, TUMOR; DISEASE-FREE SURVIVAL; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; EPIRUBICIN; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; RECEPTOR, ERBB-2; STOMACH NEOPLASMS; TREATMENT OUTCOME;

EID: 84982084091     PISSN: 14363291     EISSN: 14363305     Source Type: Journal    
DOI: 10.1007/s10120-016-0625-1     Document Type: Article

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