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Volumn 33, Issue 15, 2015, Pages 1680-1687

Predicting anthracycline benefit: TOP2A and CEP17 - Not only but also

(19)  Bartlett, John M S a,c,e   McConkey, Christopher C f   Munro, Alison F e   Desmedt, Christine j   Dunn, Janet A f   Larsimont, Denis P j   O'Malley, Frances P c   Cameron, David A e   Earl, Helena M g   Poole, Christopher J a,f   Shepherd, Lois E c,d   Cardoso, Fatima k   Jensen, Maj Britt l   Caldas, Carlos g   Twelves, Christopher J h   Rea, Daniel W i   Ejlertsen, Bent l   Leo, Angelo Di m   Pritchard, Kathleen I b  


Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; FLUOROURACIL; METHOTREXATE; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE II ALPHA; FLUORESCENT DYE; GENETIC MARKER; TUMOR ANTIGEN; TUMOR MARKER;

EID: 84933575890     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.54.7869     Document Type: Article
Times cited : (53)

References (38)
  • 1
    • 35348877882 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 status correlates with lymph node involvement in patients with estrogen receptor (ER) negative, but with grade in those with ER-positive early-stage breast cancer suitable for cytotoxic chemotherapy
    • Bartlett JM, Ellis IO, Dowsett M, et al: Human epidermal growth factor receptor 2 status correlates with lymph node involvement in patients with estrogen receptor (ER) negative, but with grade in those with ER-positive early-stage breast cancer suitable for cytotoxic chemotherapy. J Clin Oncol 25:4423-4430, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 4423-4430
    • Bartlett, J.M.1    Ellis, I.O.2    Dowsett, M.3
  • 2
    • 33646681444 scopus 로고    scopus 로고
    • HER2 and responsiveness of breast cancer to adjuvant chemotherapy
    • Pritchard KI, Shepherd LE, O'Malley FP, et al: HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med 354:2103-2111, 2006
    • (2006) N Engl J Med , vol.354 , pp. 2103-2111
    • Pritchard, K.I.1    Shepherd, L.E.2    O'Malley, F.P.3
  • 3
    • 32944475493 scopus 로고    scopus 로고
    • Retrospective analysis of topoismerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin and fluorouracil: Danish Breast Cancer Cooperative Group
    • Knoop AS, Knudsen H, Balslev E, et al: Retrospective analysis of topoismerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin and fluorouracil: Danish Breast Cancer Cooperative Group. J Clin Oncol 23:7483-7490, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 7483-7490
    • Knoop, A.S.1    Knudsen, H.2    Balslev, E.3
  • 4
    • 2542638621 scopus 로고    scopus 로고
    • Targeted therapy in breast cancer: The HER-2/neu gene and protein
    • Ross JS, Fletcher JA, Bloom KJ, et al: Targeted therapy in breast cancer: The HER-2/neu gene and protein. Mol Cell Proteomics 3:379-398, 2004
    • (2004) Mol Cell Proteomics , vol.3 , pp. 379-398
    • Ross, J.S.1    Fletcher, J.A.2    Bloom, K.J.3
  • 5
    • 0029665095 scopus 로고    scopus 로고
    • Expression of topoisomerase II alpha is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer
    • Järvinen TA, Kononen J, Peltohuikko M, et al: Expression of topoisomerase II alpha is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer. Am J Pathol 148: 2073-2082, 1996
    • (1996) Am J Pathol , vol.148 , pp. 2073-2082
    • Järvinen, T.A.1    Kononen, J.2    Peltohuikko, M.3
  • 6
    • 0037272682 scopus 로고    scopus 로고
    • Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma
    • Watters AD, Going JJ, Cooke TG, et al: Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma. Breast Cancer Res Treat 77:109-114, 2003
    • (2003) Breast Cancer Res Treat , vol.77 , pp. 109-114
    • Watters, A.D.1    Going, J.J.2    Cooke, T.G.3
  • 7
    • 58049212010 scopus 로고    scopus 로고
    • Determination of HER2 amplification by in situ hybridization: When should chromosome 17 also be determined?
    • Bartlett JMS, Campbell FM, Mallon EA: Determination of HER2 amplification by in situ hybridization: When should chromosome 17 also be determined? Am J Clin Pathol 130:920-926, 2008
    • (2008) Am J Clin Pathol , vol.130 , pp. 920-926
    • Bartlett, J.M.S.1    Campbell, F.M.2    Mallon, E.A.3
  • 8
    • 77349118709 scopus 로고    scopus 로고
    • Predictive markers of anthracycline benefit: A prospectively planned analysis of the UK National Epirubicin Adjuvant Trial (NEAT/BR9601)
    • Bartlett JM, Munro AF, Dunn JA, et al: Predictive markers of anthracycline benefit: A prospectively planned analysis of the UK National Epirubicin Adjuvant Trial (NEAT/BR9601). Lancet Oncol 11: 266-274, 2010
    • (2010) Lancet Oncol , vol.11 , pp. 266-274
    • Bartlett, J.M.1    Munro, A.F.2    Dunn, J.A.3
  • 9
    • 81255129146 scopus 로고    scopus 로고
    • HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: A meta-analysis of individual patient data
    • Di Leo A, Desmedt C, Bartlett JM, et al: HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: A meta-analysis of individual patient data. Lancet Oncol 12:1134-1142, 2011
    • (2011) Lancet Oncol , vol.12 , pp. 1134-1142
    • Di Leo, A.1    Desmedt, C.2    Bartlett, J.M.3
  • 10
    • 65549158566 scopus 로고    scopus 로고
    • Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy
    • O'Malley FP, Chia S, Tu D, et al: Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy. J Natl Cancer Inst 101:644-650, 2009
    • (2009) J Natl Cancer Inst , vol.101 , pp. 644-650
    • O'Malley, F.P.1    Chia, S.2    Tu, D.3
  • 11
    • 77957120408 scopus 로고    scopus 로고
    • Targeting anthracyclines in early breast cancer: New candidate predictive biomarkers emerge
    • Munro AF, Cameron DA, Bartlett JM: Targeting anthracyclines in early breast cancer: New candidate predictive biomarkers emerge. Oncogene 29:5231-5240, 2010
    • (2010) Oncogene , vol.29 , pp. 5231-5240
    • Munro, A.F.1    Cameron, D.A.2    Bartlett, J.M.3
  • 12
    • 84856224113 scopus 로고    scopus 로고
    • Chromosome 17 centromere (CEP17) duplication as a predictor of anthracycline response: Evidence from the NCIC Clinical Trials Group (NCIC CTG) MA.5 trial
    • Pritchard K, Munro A, O'Malley FP, et al: Chromosome 17 centromere (CEP17) duplication as a predictor of anthracycline response: Evidence from the NCIC Clinical Trials Group (NCIC CTG) MA.5 trial. Breast Cancer Res Treat 131:541-551, 2012
    • (2012) Breast Cancer Res Treat , vol.131 , pp. 541-551
    • Pritchard, K.1    Munro, A.2    O'Malley, F.P.3
  • 13
    • 69549124028 scopus 로고    scopus 로고
    • Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
    • Yeh IT, Martin MA, Robetorye RS, et al: Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event. Mod Pathol 22:1169-1175, 2009
    • (2009) Mod Pathol , vol.22 , pp. 1169-1175
    • Yeh, I.T.1    Martin, M.A.2    Robetorye, R.S.3
  • 14
    • 33750502656 scopus 로고    scopus 로고
    • Epirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer
    • Poole CJ, Earl HM, Hiller L, et al: Epirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer. N Engl J Med 355:1851-1862, 2006
    • (2006) N Engl J Med , vol.355 , pp. 1851-1862
    • Poole, C.J.1    Earl, H.M.2    Hiller, L.3
  • 15
    • 24644476579 scopus 로고    scopus 로고
    • Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: Update of National Cancer Institute of Canada Clinical Trials Group trial MA5
    • Levine MN, Pritchard KI, Bramwell VH, et al: Randomized trial comparing cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: Update of National Cancer Institute of Canada Clinical Trials Group trial MA5. J Clin Oncol 23:5166-5170, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5166-5170
    • Levine, M.N.1    Pritchard, K.I.2    Bramwell, V.H.3
  • 16
    • 0036091354 scopus 로고    scopus 로고
    • HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
    • Di Leo A, Gancberg D, Larsimont D, et al: HER-2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res 8:1107-1116, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 1107-1116
    • Di Leo, A.1    Gancberg, D.2    Larsimont, D.3
  • 17
    • 84933530275 scopus 로고    scopus 로고
    • Duplication of chromosome 17 CEP predicts for anthracycline benefit: Evidence from an international meta-analysis of 4 adjuvant breast cancer trials for the HER2/TOP2A meta-analysis study group
    • Bartlett JM, Munro A, O'Malley FP, et al: Duplication of chromosome 17 CEP predicts for anthracycline benefit: Evidence from an international meta-analysis of 4 adjuvant breast cancer trials for the HER2/TOP2A meta-analysis study group. EJC Suppl 8:121, 2010
    • (2010) EJC , pp. 121
    • Bartlett, J.M.1    Munro, A.2    O'Malley, F.P.3
  • 18
    • 20444457037 scopus 로고    scopus 로고
    • Polysomy 17 in HER-2/neu status elaboration in breast cancer: Effect on daily practice
    • Ma Y, Lespagnard L, Durbecq V, et al: Polysomy 17 in HER-2/neu status elaboration in breast cancer: Effect on daily practice. Clin Cancer Res 11:4393-4399, 2005
    • (2005) Clin Cancer Res , vol.11 , pp. 4393-4399
    • Ma, Y.1    Lespagnard, L.2    Durbecq, V.3
  • 19
    • 0035875815 scopus 로고    scopus 로고
    • Phase III trial comparing two dose levels of epirubicin combined with cyclophosphamide with cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer
    • Piccart MJ, Di Leo A, Beauduin M, et al: Phase III trial comparing two dose levels of epirubicin combined with cyclophosphamide with cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer. J Clin Oncol 19:3103-3110, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 3103-3110
    • Piccart, M.J.1    Di Leo, A.2    Beauduin, M.3
  • 20
    • 33947135012 scopus 로고    scopus 로고
    • Improved outcome from substituting methotrexate with epirubicin: Results from a randomised comparison of CMF versus CEF in patients with primary breast cancer
    • Ejlertsen B, Mouridsen HT, Jensen MB, et al: Improved outcome from substituting methotrexate with epirubicin: Results from a randomised comparison of CMF versus CEF in patients with primary breast cancer. Eur J Cancer 43:877-884, 2007
    • (2007) Eur J Cancer , vol.43 , pp. 877-884
    • Ejlertsen, B.1    Mouridsen, H.T.2    Jensen, M.B.3
  • 21
    • 24944452378 scopus 로고    scopus 로고
    • REporting recommendations for tumour MARKer Prognostic Studies (REMARK)
    • McShane LM, Altman DG, Sauerbrei W, et al: REporting recommendations for tumour MARKer Prognostic Studies (REMARK). Br J Cancer 93:387-391, 2005
    • (2005) Br J Cancer , vol.93 , pp. 387-391
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3
  • 22
    • 0037809375 scopus 로고    scopus 로고
    • A role for BRCA1 in sporadic breast cancer
    • Fraser JA, Reeves JR, Stanton PD, et al: A role for BRCA1 in sporadic breast cancer. Br J Cancer 88:1263-1270, 2003
    • (2003) Br J Cancer , vol.88 , pp. 1263-1270
    • Fraser, J.A.1    Reeves, J.R.2    Stanton, P.D.3
  • 23
    • 0242610903 scopus 로고    scopus 로고
    • p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells
    • Fraser M, Leung BM, Yan X, et al: p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells. Cancer Res 63:7081-7088, 2003
    • (2003) Cancer Res , vol.63 , pp. 7081-7088
    • Fraser, M.1    Leung, B.M.2    Yan, X.3
  • 24
    • 34548391416 scopus 로고    scopus 로고
    • DNA topoisomerase II, genotoxicity, and cancer
    • McClendon AK, Osheroff N: DNA topoisomerase II, genotoxicity, and cancer. Mutat Res 623:83-97, 2007
    • (2007) Mutat Res , vol.623 , pp. 83-97
    • McClendon, A.K.1    Osheroff, N.2
  • 25
    • 57649138720 scopus 로고    scopus 로고
    • Recent advances in p53 research: An interdisciplinary perspective
    • Olivier M, Petitjean A, Marcel V, et al: Recent advances in p53 research: An interdisciplinary perspective. Cancer Gene Ther 16:1-12, 2009
    • (2009) Cancer Gene Ther , vol.16 , pp. 1-12
    • Olivier, M.1    Petitjean, A.2    Marcel, V.3
  • 26
    • 46449130565 scopus 로고    scopus 로고
    • Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network
    • Greenberg RA: Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network. Chromosoma 117:305-317, 2008
    • (2008) Chromosoma , vol.117 , pp. 305-317
    • Greenberg, R.A.1
  • 27
    • 42549111727 scopus 로고    scopus 로고
    • Genomic analysis of the HER2//TOP2A amplicon in breast cancer and breast cancer cell lines
    • Arriola E, Marchio C, Tan DS, et al: Genomic analysis of the HER2//TOP2A amplicon in breast cancer and breast cancer cell lines. Lab Invest 88:491-503, 2008
    • (2008) Lab Invest , vol.88 , pp. 491-503
    • Arriola, E.1    Marchio, C.2    Tan, D.S.3
  • 28
    • 0028354305 scopus 로고
    • c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer
    • Muss HB, Thor AD, Berry DA, et al: c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 330:1260-1266, 1994
    • (1994) N Engl J Med , vol.330 , pp. 1260-1266
    • Muss, H.B.1    Thor, A.D.2    Berry, D.A.3
  • 29
    • 23044452221 scopus 로고    scopus 로고
    • HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients
    • Del Mastro L, Bruzzi P, Nicolo G, et al: HER2 expression and efficacy of dose-dense anthracycline-containing adjuvant chemotherapy in breast cancer patients. Br J Cancer 93:7-14, 2005
    • (2005) Br J Cancer , vol.93 , pp. 7-14
    • Del Mastro, L.1    Bruzzi, P.2    Nicolo, G.3
  • 30
    • 56949083950 scopus 로고    scopus 로고
    • Topoisomerase II alpha as a marker predicting anthracyclines' activity in early breast cancer patients: Ready for the primetime?
    • Di Leo A, Biganzoli L, Claudino W, et al: Topoisomerase II alpha as a marker predicting anthracyclines' activity in early breast cancer patients: Ready for the primetime? Eur J Cancer 44:2791-2798, 2008
    • (2008) Eur J Cancer , vol.44 , pp. 2791-2798
    • Di Leo, A.1    Biganzoli, L.2    Claudino, W.3
  • 31
    • 4043131642 scopus 로고    scopus 로고
    • HER-2/neu as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
    • Di Leo A, Chan S, Paesmans M, et al: HER-2/neu as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel. Breast Cancer Res Treat 86:197-206, 2004
    • (2004) Breast Cancer Res Treat , vol.86 , pp. 197-206
    • Di Leo, A.1    Chan, S.2    Paesmans, M.3
  • 32
    • 0032538040 scopus 로고    scopus 로고
    • erbB-2 and response to doxorubicin in patients with axillary lymph node- positive, hormone receptor-negative breast cancer
    • Paik S, Bryant J, Park C, et al: erbB-2 and response to doxorubicin in patients with axillary lymph node- positive, hormone receptor-negative breast cancer. J Natl Cancer Inst 90:1361-1370, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1361-1370
    • Paik, S.1    Bryant, J.2    Park, C.3
  • 33
    • 0034694659 scopus 로고    scopus 로고
    • HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project protocol B-15
    • Paik S, Bryant J, Tan-Chiu E, et al: HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project protocol B-15. J Natl Cancer Inst 92:1991-1998, 2000
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1991-1998
    • Paik, S.1    Bryant, J.2    Tan-Chiu, E.3
  • 34
    • 39149126730 scopus 로고    scopus 로고
    • HER-2 and topoisomerase II as predictors of response to chemotherapy
    • Pritchard KI, Messersmith H, Elavathil L, et al: HER-2 and topoisomerase II as predictors of response to chemotherapy. J Clin Oncol 26:736-744, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 736-744
    • Pritchard, K.I.1    Messersmith, H.2    Elavathil, L.3
  • 35
    • 65649141497 scopus 로고    scopus 로고
    • Chromosome 17 polysomy (Ch17) as a predictor of anthracycline response: Emerging evidence from the UK NEAT adjuvant breast cancer trial
    • Bartlett JMS, Munro A, Dunn JA, et al: Chromosome 17 polysomy (Ch17) as a predictor of anthracycline response: Emerging evidence from the UK NEAT adjuvant breast cancer trial. Cancer Res 69:74S, 2009
    • (2009) Cancer Res , vol.69 , pp. 74S
    • Bartlett, J.M.S.1    Munro, A.2    Dunn, J.A.3
  • 36
    • 54849441046 scopus 로고    scopus 로고
    • Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial
    • Bartlett JM, Munro A, Cameron DA, et al: Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial. J Clin Oncol 26:5027-5035, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 5027-5035
    • Bartlett, J.M.1    Munro, A.2    Cameron, D.A.3
  • 37
    • 1542343905 scopus 로고    scopus 로고
    • Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples
    • Mueller RE, Parkes RK, Andrulis I, et al: Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples. Genes Chromosomes Cancer 39:288-297, 2004
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 288-297
    • Mueller, R.E.1    Parkes, R.K.2    Andrulis, I.3
  • 38
    • 79952323665 scopus 로고    scopus 로고
    • Alteration of topoisomerase II-alpha gene in human breast cancer: Association with responsiveness to anthracycline-based chemotherapy
    • Press MF, Sauter G, Buyse M, et al: Alteration of topoisomerase II-alpha gene in human breast cancer: Association with responsiveness to anthracycline-based chemotherapy. J Clin Oncol 29:859-867, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 859-867
    • Press, M.F.1    Sauter, G.2    Buyse, M.3


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