Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins

Nature Biotechnology

Volumn 34, Issue 8, 2016, Pages 807-808

  Hur, Junho K ^a   Kim, Kyoungmi ^a   Been, Kyung Wook ^a,b   Baek, Gayoung ^a   Ye, Sunghyeok ^a,c   Hur, Junseok W ^a,d   Ryu, Seuk Min ^a,b   Lee, Youn Su ^a,e   Kim, Jin Soo ^a,b  

^a Institute for Basic Science   (South Korea)

^b Seoul National University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e ToolGen Inc   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CPF1 PROTEIN; DEOXYRIBONUCLEASE I; FORKHEAD BOX PROTEIN N1; FORKHEAD TRANSCRIPTION FACTOR; RECOMBINANT PROTEIN; RIBONUCLEOPROTEIN; T7 ENDONUCLEASE 1; UNCLASSIFIED DRUG; VASCULOTROPIN A;

3T3 CELL LINE; ACIDAMINOCOCCUS; ALLELE; ANIMAL EXPERIMENT; BLASTOCYST; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CRISPR CAS SYSTEM; ELECTROPORATION; EMBRYO; ESCHERICHIA COLI; FEMALE; GENE INACTIVATION; GENE SEQUENCE; GENE TARGETING; IN VITRO STUDY; INDEL MUTATION; LETTER; MICROINJECTION; MOUSE; MOUSE EMBRYO; MOUSE MUTANT; MUTAGENESIS; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; STREPTOCOCCUS PYOGENES; ANIMAL; GENE EDITING; GENETIC TRANSFECTION; GENETICS; PROCEDURES; SITE DIRECTED MUTAGENESIS; TRANSGENIC MOUSE;

ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; ELECTROPORATION; GENE EDITING; GENE TARGETING; MICE; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; RIBONUCLEOPROTEINS; TRANSFECTION;

EID: 84981342035     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3596     Document Type: Letter

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