Immunoproteomic analysis of antibody responses to extracellular proteins of candida albicans revealing the importance of glycosylation for antigen recognition

Journal of Proteome Research

Volumn 15, Issue 8, 2016, Pages 2394-2406

  Luo, Ting ^a,b   Krüger, Thomas ^a   Knüpfer, Uwe ^a   Kasper, Lydia ^a   Wielsch, Natalie ^c   Hube, Bernhard ^a,b,d   Kortgen, Andreas ^b   Bauer, Michael ^b   Giamarellos Bourboulis, Evangelos J ^b,e   Dimopoulos, George ^e   Brakhage, Axel A ^a,d   Kniemeyer, Olaf ^a,b,d  

^a HANS KNÖLL INSTITUTE   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

^c MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^e UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

antigens; Candida albicans; extracellular proteins; glycosylation; immunoproteomics; secretome; SERPA; yeast to hypha transition

Indexed keywords

ASPARTIC PROTEINASE; FUNGAL PROTEIN; FUNGUS ANTIGEN; GLYCOSYLATED PROTEIN; IMMUNOGLOBULIN G ANTIBODY; ANTIBODY; POLYSACCHARIDE; SAP6 PROTEIN, CANDIDA ALBICANS;

ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CANDIDA ALBICANS; CANDIDEMIA; CONTROLLED STUDY; CROSS REACTION; DEGLYCOSYLATION; ENZYME RELEASE; FUNGUS HYPHAE; HUMAN; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN GLYCOSYLATION; PROTEOMICS; SEROLOGY; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; YEAST; ANTIGEN ANTIBODY REACTION; CHEMISTRY; GLYCOSYLATION; HOST PATHOGEN INTERACTION; IMMUNOLOGY; PATHOGENICITY; PROCEDURES; SECRETION (PROCESS);

ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; ASPARTIC ACID ENDOPEPTIDASES; CANDIDA ALBICANS; CHROMATOGRAPHY, LIQUID; FUNGAL PROTEINS; GLYCOSYLATION; HOST-PATHOGEN INTERACTIONS; HUMANS; HYPHAE; POLYSACCHARIDES; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84981316080     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b01065     Document Type: Article

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