Expression of brain-derived neurotrophic factor, IGF-1 and cortisol elicited by regular aerobic exercise in adolescents

Journal of Physical Therapy Science

Volumn 27, Issue 3, 2015, Pages 737-741

  Jeon, Yong Kyun ^a   Ha, Chang Ho ^b,c  

^a Dankook University   (South Korea)

^b Dongguk University   (South Korea)

^c NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

Adolescents; Aerobic exercise; BDNF

Indexed keywords

EID: 84981297721     PISSN: 09155287     EISSN: None     Source Type: Journal    
DOI: 10.1589/jpts.27.737     Document Type: Article

References (34)

1. Mizuno M, Yamada K, Olariu A, et al.: Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J Neurosci, 2000, 20: 7116–7121.
2. Soya H, Nakamura T, Deocaris CC, et al.: BDNF induction with mild exercise in the rat hippocampus. Biochem Biophys Res Commun, 2007, 358: 961–967.
3. Seifert T, Brassard P, Wissenberg M, et al.: Endurance training enhances BDNF release from the human brain. Am J Physiol Regul Integr Comp Physiol, 2010, 298: R372–R377.
4. Rice D, Barone S Jr: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect, 2000, 108: 511–533.
5. Cotman CW, Berchtold NC: Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci, 2002, 25: 295–301.
6. Russo-Neustadt A, Ha T, Ramirez R, et al.: Physical activity-antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav Brain Res, 2001, 120: 87–95.
7. Kim G, Kim E: The effects of antecedent exercise on motor function recovery and brain-derived neurotrophic factor expression after focal cerebral ischemia in rats. J Phys Ther Sci, 2013, 25: 553–556.
8. Sairanen M, Lucas G, Ernfors P, et al.: Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci, 2005, 25: 1089–1094.
9. Pyun MY, Cho HS, Jeon JY, et al.: Effect of aerobic exercise on factors relative to the brain nerve growth in girls. J Life Sci, 2010, 20: 948–954.
10. Lessmann V, Brigadski T: Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neurosci Res, 2009, 65: 11–22.
11. Zoladz JA, Pilc A, Majerczak J, et al.: Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. J Physiol Pharmacol, 2008, 59: 119–132.
12. Carro E, Trejo JL, Busiguina S, et al.: Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J Neurosci, 2001, 21: 5678–5684.
13. Arsenijevic Y, Weiss S: Insulin-like growth factor-I is a differentiation factor for postmitotic CNS stem cell-derived neuronal precursors: distinct actions from those of brain-derived neurotrophic factor. J Neurosci, 1998, 18: 2118–2128.
14. Reinhardt RR, Bondy CA: Insulin-like growth factors cross the bloodbrain barrier. Endocrinology, 1994, 135: 1753–1761.
15. Gould E, McEwen BS, Tanapat P, et al.: Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci, 1997, 17: 2492–2498.
16. Zheng K, Shea PY, Le L, et al.: The effects of voluntary, involuntary, and forced exercise on Brain-Derived Neurotrophic Factor and Motor function recovery: a rat brain ischemia model. PLoS ONE, 2010, 6: e16643.
17. American College of Sports Medicine: ACSM’s guidelines for exercise testing and prescription, 8th ed. Philadelphia: Lippincott Williams & Wilkins, 2010.
18. Goekint M, De Pauw K, Roelands B, et al.: Strength training does not influence serum brain-derived neurotrophic factor. Eur J Appl Physiol, 2010, 110: 285–293.
19. Bos I, Jacobs L, Nawrot TS, et al.: No exercise-induced increase in serum BDNF after cycling near a major traffic road. Neurosci Lett, 2011, 500: 129–132.
20. Erickson KI, Voss MW, Prakash RS, et al.: Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci USA, 2011, 108: 3017–3022.
21. Griffin ÉW, Mullally S, Foley C, et al.: Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males. Physiol Behav, 2011, 104: 934–941.
22. Heyman E, Gamelin FX, Goekint M, et al.: Intense exercise increases circulating endocannabinoid and BDNF levels in humans—possible implications for reward and depression. Psychoneuroendocrinology, 2012, 37: 844–851.
23. Nofuji Y, Suwa M, Moriyama Y, et al.: Decreased serum brain-derived neurotrophic factor in trained men. Neurosci Lett, 2008, 437: 29–32.
24. Uysal N, Tugyan K, Kayatekin BM, et al.: The effects of regular aerobic exercise in adolescent period on hippocampal neuron density, apoptosis and spatial memory. Neurosci Lett, 2005, 383: 241–245.
25. Seifert T, Brassard P, Wissenberg M, et al.: Endurance training enhances BDNF release from the human brain. Am J Physiol Regul Integr Comp Physiol, 2010, 298: R372–R377.
26. Gómez-Pinilla F, Ying Z, Opazo P, et al.: Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle. Eur J Neurosci, 2001, 13: 1078–1084.
27. Ruscheweyh R, Willemer C, Krüger K, et al.: Physical activity and memory functions: an interventional study. Neurobiol Aging, 2011, 32: 1304– 1319.
28. Lee SS, Yoo JH, Kang S, et al.: The effects of 12 weeks regular aerobic exercise on brain-derived neurotrophic factor and inflammatory factors in juvenile obesity and type 2 diabetes mellitus. J Phys Ther Sci, 2014, 26: 1199–1204.
29. Ferris LT, Williams JS, Shen CL: The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Med Sci Sports Exerc, 2007, 39: 728–734.
30. Fan J, Molina PE, Gelato MC, et al.: Differential tissue regulation of insulin-like growth factor-I content and binding proteins after endotoxin. Endocrinology, 1994, 134: 1685–1692.
31. Tomori K, Kobayash R, Koseki T, et al.: Effect of neuromuscular electrical stimulation of denervated muscle on the mRNA expression of IGFs in rat skeletal muscle and sciatic nerve. J Phys Ther Sci, 2009, 21: 269–273.
32. Lee KJ, Rhyu IJ: Effects of exercise on structural and functional changes in the aging brain. J Korean Med Assoc, 2009, 52: 907–919.
33. Laron Z, Avitzur Y, Klinger B: Carbohydrate metabolism in primary growth hormone resistance (Laron syndrome) before and during insulinlike growth factor-I treatment. Metabolism, 1995, 44: 113–118.
34. Rojas Vega S, Strüder HK, Vera Wahrmann B, et al.: Acute BDNF and cortisol response to low intensity exercise and following ramp incremental exercise to exhaustion in humans. Brain Res, 2006, 1121: 59–65.