-
1
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
-
2
-
-
84906673582
-
Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease
-
Fox, I. J. et al. Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease. Science 345, 1247391 (1-10) (2014).
-
(2014)
Science
, vol.345
, Issue.1-10
, pp. 1247391
-
-
Fox, I.J.1
-
3
-
-
84912058317
-
IPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinsons disease
-
Woodard, C. M. et al. iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinsons disease. Cell Rep 9, 1173-1182 (2014).
-
(2014)
Cell Rep
, vol.9
, pp. 1173-1182
-
-
Woodard, C.M.1
-
4
-
-
3142521479
-
Stem cell therapy for human neurodegenerative disorders-how to make it work
-
Lindvall, O., Kokaia, Z. & Martinez-Serrano, A. Stem cell therapy for human neurodegenerative disorders-how to make it work. Nature Med 10 Suppl, S42-S50 (2004).
-
(2004)
Nature Med
, vol.10
, pp. S42-S50
-
-
Lindvall, O.1
Kokaia, Z.2
Martinez-Serrano, A.3
-
5
-
-
84955358038
-
Grafted human ips cell-derived oligodendrocyte precursor cells contribute to robust remyelination of demyelinated axons after spinal cord injury
-
Kawabata, S. et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports 6, 1-8 (2016).
-
(2016)
Stem Cell Reports
, vol.6
, pp. 1-8
-
-
Kawabata, S.1
-
6
-
-
84872013374
-
Adapting human pluripotent stem cells to high-Throughput and high-content screening
-
Desbordes, S. C. & Studer, L. Adapting human pluripotent stem cells to high-Throughput and high-content screening. Nat Protoc 8, 111-130 (2013).
-
(2013)
Nat Protoc
, vol.8
, pp. 111-130
-
-
Desbordes, S.C.1
Studer, L.2
-
7
-
-
84921718446
-
Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders
-
Schadt, E. E., Buchanan, S., Brennand, K. J. & Merchant, K. M. Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders. Front Pharmacol 5, 252 (1-15) (2014).
-
(2014)
Front Pharmacol
, vol.5
, Issue.1-15
, pp. 252
-
-
Schadt, E.E.1
Buchanan, S.2
Brennand, K.J.3
Merchant, K.M.4
-
8
-
-
84871459930
-
Fabrication of mouse embryonic stem cell-derived layered cardiac cell sheets using a bioreactor culture system
-
Matsuura, K. et al. Fabrication of mouse embryonic stem cell-derived layered cardiac cell sheets using a bioreactor culture system. PLoS One 7, e52176 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e52176
-
-
Matsuura, K.1
-
9
-
-
84923796564
-
Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture
-
Kempf, H. et al. Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture. Stem Cell Reports 3, 1132-1146 (2014).
-
(2014)
Stem Cell Reports
, vol.3
, pp. 1132-1146
-
-
Kempf, H.1
-
10
-
-
84900340823
-
A 3D sphere culture system containing functional polymers for large-scale human pluripotent stem cell production
-
Otsuji, T. G. et al. A 3D sphere culture system containing functional polymers for large-scale human pluripotent stem cell production. Stem Cell Reports 2, 734-745 (2014).
-
(2014)
Stem Cell Reports
, vol.2
, pp. 734-745
-
-
Otsuji, T.G.1
-
11
-
-
84891352376
-
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
-
Lei, Y. & Schaffer, D. V. A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation. Proc Natl Acad Sci USA 110, E5039-E5048 (2013).
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E5039-E5048
-
-
Lei, Y.1
Schaffer, D.V.2
-
12
-
-
45349084219
-
Reproducible, ultra high-Throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates
-
Ungrin, M. D., Joshi, C., Nica, A., Bauwens, C. & Zandstra, P. W. Reproducible, ultra high-Throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates. PLoS One 3, e1565 (2008).
-
(2008)
PLoS One
, vol.3
, pp. e1565
-
-
Ungrin, M.D.1
Joshi, C.2
Nica, A.3
Bauwens, C.4
Zandstra, P.W.5
-
13
-
-
84934299022
-
Formation of well-defined embryoid bodies from dissociated human induced pluripotent stem cells using microfabricated cell-repellent microwell arrays
-
Pettinato, G., Wen, X. & Zhang, N. Formation of well-defined embryoid bodies from dissociated human induced pluripotent stem cells using microfabricated cell-repellent microwell arrays. Sci Rep 4, 7402 (2014).
-
(2014)
Sci Rep
, vol.4
, pp. 7402
-
-
Pettinato, G.1
Wen, X.2
Zhang, N.3
-
14
-
-
28744433557
-
Bioreactor design for tissue engineering
-
Portner, R., Nagel-Heyer, S., Goepfert, C., Adamietz, P. & Meenen, N. M. Bioreactor design for tissue engineering. J Biosci Bioeng 100, 235-245 (2005).
-
(2005)
J Biosci Bioeng
, vol.100
, pp. 235-245
-
-
Portner, R.1
Nagel-Heyer, S.2
Goepfert, C.3
Adamietz, P.4
Meenen, N.M.5
-
15
-
-
77954937162
-
Reduced differentiation efficiency of murine embryonic stem cells in stirred suspension bioreactors
-
Taiani, J. T. et al. Reduced differentiation efficiency of murine embryonic stem cells in stirred suspension bioreactors. Stem Cells Dev 19, 989-998 (2010).
-
(2010)
Stem Cells Dev
, vol.19
, pp. 989-998
-
-
Taiani, J.T.1
-
16
-
-
55049120510
-
Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories
-
Bauwens, C. L. et al. Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories. Stem Cells 26, 2300-2310 (2008).
-
(2008)
Stem Cells
, vol.26
, pp. 2300-2310
-
-
Bauwens, C.L.1
-
17
-
-
36048953007
-
Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies
-
Koike, M., Sakaki, S., Amano, Y. & Kurosawa, H. Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies. J Biosci Bioeng 104, 294-299 (2007).
-
(2007)
J Biosci Bioeng
, vol.104
, pp. 294-299
-
-
Koike, M.1
Sakaki, S.2
Amano, Y.3
Kurosawa, H.4
-
18
-
-
70350126572
-
Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11
-
Hwang, Y. S. et al. Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc Natl Acad Sci USA 106, 16978-16983 (2009).
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16978-16983
-
-
Hwang, Y.S.1
-
19
-
-
84899563340
-
Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells
-
Pesl, M. et al. Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells. Heart Vessels 29, 834-846 (2014).
-
(2014)
Heart Vessels
, vol.29
, pp. 834-846
-
-
Pesl, M.1
-
20
-
-
84881593966
-
Standardized generation and differentiation of neural precursor cells from human pluripotent stem cells
-
Kozhich, O. A., Hamilton, R. S. & Mallon, B. S. Standardized generation and differentiation of neural precursor cells from human pluripotent stem cells. Stem Cell Rev 9, 531-536 (2013).
-
(2013)
Stem Cell Rev
, vol.9
, pp. 531-536
-
-
Kozhich, O.A.1
Hamilton, R.S.2
Mallon, B.S.3
-
21
-
-
84924219720
-
Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice
-
Kondo, T. et al. Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice. Stem Cell Reports 3, 242-249 (2014).
-
(2014)
Stem Cell Reports
, vol.3
, pp. 242-249
-
-
Kondo, T.1
-
22
-
-
33646726733
-
Notch promotes neural lineage entry by pluripotent embryonic stem cells
-
Lowell, S., Benchoua, A., Heavey, B. & Smith, A. G. Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol 4, e121 (2006).
-
(2006)
PLoS Biol
, vol.4
, pp. e121
-
-
Lowell, S.1
Benchoua, A.2
Heavey, B.3
Smith, A.G.4
-
23
-
-
84888870688
-
High-Throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias
-
Nazareth, E. J. et al. High-Throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias. Nat Methods 10, 1225-1231 (2013).
-
(2013)
Nat Methods
, vol.10
, pp. 1225-1231
-
-
Nazareth, E.J.1
-
24
-
-
77951204701
-
The role of FGF-signaling in early neural specification of human embryonic stem cells
-
Cohen, M. A., Itsykson, P. & Reubinoff, B. E. The role of FGF-signaling in early neural specification of human embryonic stem cells. Dev Biol 340, 450-458 (2010).
-
(2010)
Dev Biol
, vol.340
, pp. 450-458
-
-
Cohen, M.A.1
Itsykson, P.2
Reubinoff, B.E.3
-
25
-
-
79952196280
-
Intrinsic transition of embryonic stem-cell differentiation into neural progenitors
-
Kamiya, D. et al. Intrinsic transition of embryonic stem-cell differentiation into neural progenitors. Nature 470, 503-509 (2011).
-
(2011)
Nature
, vol.470
, pp. 503-509
-
-
Kamiya, D.1
-
26
-
-
68749115159
-
Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture
-
Lock, L. T. & Tzanakakis, E. S. Expansion and differentiation of human embryonic stem cells to endoderm progeny in a microcarrier stirred-suspension culture. Tissue Eng Part A 15, 2051-2063 (2009).
-
(2009)
Tissue Eng Part A
, vol.15
, pp. 2051-2063
-
-
Lock, L.T.1
Tzanakakis, E.S.2
-
27
-
-
4644262521
-
Retinoic-Acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells
-
Okada, Y., Shimazaki, T., Sobue, G. & Okano, H. Retinoic-Acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells. Dev Biol 275, 124-142 (2004).
-
(2004)
Dev Biol
, vol.275
, pp. 124-142
-
-
Okada, Y.1
Shimazaki, T.2
Sobue, G.3
Okano, H.4
-
28
-
-
84981186137
-
Induced pluripotent stem cells for modeling neurological disorders
-
Russo, F. B., Cugola, F. R., Fernandes, I. R., Pignatari, G. C. & Beltrao-Braga, P. C. Induced pluripotent stem cells for modeling neurological disorders. World J Transplant 5, 209-221 (2015).
-
(2015)
World J Transplant
, vol.5
, pp. 209-221
-
-
Russo, F.B.1
Cugola, F.R.2
Fernandes, I.R.3
Pignatari, G.C.4
Beltrao-Braga, P.C.5
-
29
-
-
60849086260
-
Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation
-
Bratt-Leal, A. M., Carpenedo, R. L. & McDevitt, T. C. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol Prog 25, 43-51 (2009).
-
(2009)
Biotechnol Prog
, vol.25
, pp. 43-51
-
-
Bratt-Leal, A.M.1
Carpenedo, R.L.2
McDevitt, T.C.3
-
30
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
Chambers, S. M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol 27, 275-280 (2009).
-
(2009)
Nat Biotechnol
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
-
31
-
-
78650197228
-
Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells
-
Morizane, A., Doi, D., Kikuchi, T., Nishimura, K. & Takahashi, J. Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells. J Neurosci Res 89, 117-126 (2011).
-
(2011)
J Neurosci Res
, vol.89
, pp. 117-126
-
-
Morizane, A.1
Doi, D.2
Kikuchi, T.3
Nishimura, K.4
Takahashi, J.5
-
32
-
-
84896372198
-
Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors
-
Lippmann, E. S., Estevez-Silva, M. C. & Ashton, R. S. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells 32, 1032-1042 (2014).
-
(2014)
Stem Cells
, vol.32
, pp. 1032-1042
-
-
Lippmann, E.S.1
Estevez-Silva, M.C.2
Ashton, R.S.3
-
33
-
-
78651062639
-
Nestin is required for the proper self-renewal of neural stem cells
-
Park, D. et al. Nestin is Required for the Proper Self-Renewal of Neural Stem Cells. Stem Cells 28, 2162-2171 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 2162-2171
-
-
Park, D.1
-
34
-
-
51649093059
-
Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium
-
Furue, M. K. et al. Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium. Proc Natl Acad Sci USA 105, 13409-13414 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13409-13414
-
-
Furue, M.K.1
-
35
-
-
79961146650
-
Microfluidic perfusion for regulating diffusible signaling in stem cells
-
Blagovic, K., Kim, L. Y. & Voldman, J. Microfluidic perfusion for regulating diffusible signaling in stem cells. PLoS One 6, e22892 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e22892
-
-
Blagovic, K.1
Kim, L.Y.2
Voldman, J.3
-
36
-
-
78149342807
-
Neural induction intermediates exhibit distinct roles of Fgf signaling
-
Sterneckert, J. et al. Neural induction intermediates exhibit distinct roles of Fgf signaling. Stem Cells 28, 1772-1781 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1772-1781
-
-
Sterneckert, J.1
-
37
-
-
34547108569
-
Microfabrication-based modulation of embryonic stem cell differentiation
-
Park, J. et al. Microfabrication-based modulation of embryonic stem cell differentiation. Lab Chip 7 (2007).
-
(2007)
Lab Chip
, vol.7
-
-
Park, J.1
-
38
-
-
83055173311
-
High density cultures of embryoid bodies enhanced cardiac differentiation of murine embryonic stem cells
-
Lee, M. Y. et al. High density cultures of embryoid bodies enhanced cardiac differentiation of murine embryonic stem cells. Biochem Biophys Res Commun 416, 51-57 (2011).
-
(2011)
Biochem Biophys Res Commun
, vol.416
, pp. 51-57
-
-
Lee, M.Y.1
-
39
-
-
84940601627
-
Automated, high-Throughput derivation, characterization and differentiation of induced pluripotent stem cells
-
Paull, D. et al. Automated, high-Throughput derivation, characterization and differentiation of induced pluripotent stem cells. Nat Methods 12, 885-889 (2015).
-
(2015)
Nat Methods
, vol.12
, pp. 885-889
-
-
Paull, D.1
-
40
-
-
84947708825
-
Long-Term maintenance of human induced pluripotent stem cells by automated cell culture system
-
Konagaya, S., Ando, T., Yamauchi, T., Suemori, H. & Iwata, H. Long-Term maintenance of human induced pluripotent stem cells by automated cell culture system. Sci Rep 5, 16647 (2015).
-
(2015)
Sci Rep
, vol.5
, pp. 16647
-
-
Konagaya, S.1
Ando, T.2
Yamauchi, T.3
Suemori, H.4
Iwata, H.5
-
41
-
-
84896084435
-
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation
-
Doi, D. et al. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem Cell Reports 2, 337-350 (2014).
-
(2014)
Stem Cell Reports
, vol.2
, pp. 337-350
-
-
Doi, D.1
-
42
-
-
65649115029
-
Directed differentiation of human-induced pluripotent stem cells generates active motor neurons
-
Karumbayaram, S. et al. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells 27, 806-811 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 806-811
-
-
Karumbayaram, S.1
|