Mitochondrial lipid transport and biosynthesis: A complex balance

Journal of Cell Biology

Volumn 214, Issue 1, 2016, Pages 9-11

  Mesmin, Bruno ^a,b  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLYASE; LIPID; LIPID TRANSFER PROTEIN; MITOCHONDRIAL ENZYME; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; PROTEIN; PROTEIN MDM35; PROTEIN UPS2; UNCLASSIFIED DRUG;

ARTICLE; ENDOPLASMIC RETICULUM MEMBRANE; GLYCOLYSIS; HUMAN; INNER MEMBRANE; LIPID TRANSPORT; LIPOGENESIS; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; YEAST; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; LIPID METABOLISM; METABOLISM; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; HUMANS; LIPID METABOLISM; LIPIDS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MODELS, BIOLOGICAL; SACCHAROMYCES CEREVISIAE;

EID: 84979996726     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201606069     Document Type: Article

References (19)

1. Aaltonen, M.J., J.R. Friedman, C. Osman, B. Salin, J.P. di Rago, J. Nunnari, T. Langer, and T. Tatsuta. 2016. MIC OS and phospholipid transfer by Ups2-Mdm35 organize membrane lipid synthesis in mitochondria. J. Cell Biol. 213:525-534. http ://dx.doi.org/10.1083/jcb.201602007
2. AhYoung, A.P., J. Jiang, J. Zhang, X. Khoi Dang, J.A. Loo, Z.H. Zhou, and P.F. Egea. 2015. Conserved SMP domains of the ERM ES complex bind phospholipids and mediate tether assembly. Proc. Natl. Acad. Sci. USA. 112:E3179-E3188. http ://dx.doi.org/10.1073/pnas.1422363112
3. Böttinger, L., S.E. Horvath, T. Kleinschroth, C. Hunte, G. Daum, N. Pfanner, and T. Becker. 2012. Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes. J. Mol. Biol. 423:677-686. http ://dx.doi.org/10.1016/j.jmb.2012.09.001
4. Chung, J., F. Torta, K. Masai, L. Lucast, H. Czapla, L.B. Tanner, P. Narayanaswamy, M.R. Wenk, F. Nakatsu, and P. De Camilli. 2015. PI4P/phosphatidylserine countertransport at ORP5-and ORP8-mediated ER-plasma membrane contacts. Science. 349:428-432. http ://dx.doi.org/10.1126/science.aab1370
5. Clancey, C.J., S.C. Chang, and W. Dowhan. 1993. Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant. J. Biol. Chem. 268:24580-24590.
6. Connerth, M., T. Tatsuta, M. Haag, T. Klecker, B. Westermann, and T. Langer. 2012. Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein. Science. 338:815-818. http ://dx.doi.org/10.1126/science.1225625
7. Kornmann, B., E. Currie, S.R. Collins, M. Schuldiner, J. Nunnari, J.S. Weissman, and P. Walter. 2009. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 325:477-481. http ://dx.doi.org/10.1126/science.1175088
8. Levine, T. 2004. Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions. Trends Cell Biol. 14:483-490. http ://dx.doi.org/10.1016/j.tcb.2004.07.017
9. Miyata, N., Y. Watanabe, Y. Tamura, T. Endo, and O. Kuge. 2016. Phosphatidylserine transport by Ups2-Mdm35 in respiration-active mitochondria. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601082
10. Moser von Filseck, J., A. Copic, V. Delfosse, S. Vanni, C.L. Jackson, W. Bourguet, and G. Drin. 2015. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate. Science. 349:432-436. http ://dx.doi.org/10.1126/science.aab1346
11. Osman, C., M. Haag, C. Potting, J. Rodenfels, P.V. Dip, F.T. Wieland, B. Brügger, B. Westermann, and T. Langer. 2009. The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J. Cell Biol. 184:583-596. http ://dx.doi.org/10.1083/jcb.200810189
12. Pfanner, N., M. van der Laan, P. Amati, R.A. Capaldi, A.A. Caudy, A. Chacinska, M. Darshi, M. Deckers, S. Hoppins, T. Icho, et al. 2014. Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J. Cell Biol. 204:1083-1086. http ://dx.doi.org/10.1083/jcb.201401006
13. Potting, C., T. Tatsuta, T. König, M. Haag, T. Wai, M.J. Aaltonen, and T. Langer. 2013. TRI AP1/PRE LI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid. Cell Metab. 18:287-295. http ://dx.doi.org/10.1016/j.cmet.2013.07.008
14. Steenbergen, R., T.S. Nanowski, A. Beigneux, A. Kulinski, S.G. Young, and J.E. Vance. 2005. Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects. J. Biol. Chem. 280:40032-40040. http ://dx.doi.org/10.1074/jbc.M506510200
15. Tamura, Y., T. Endo, M. Iijima, and H. Sesaki. 2009. Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J. Cell Biol. 185:1029-1045. http ://dx.doi.org/10.1083/jcb.200812018
16. Tamura, Y., M. Iijima, and H. Sesaki. 2010. Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formation. EMBO J. 29:2875-2887. http ://dx.doi.org/10.1038/emboj.2010.149
17. Trotter, P.J., J. Pedretti, and D.R. Voelker. 1993. Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele. J. Biol. Chem. 268:21416-21424.
18. Vance, J.E. 2015. Phospholipid synthesis and transport in mammalian cells. Traffic. 16:1-18. http ://dx.doi.org/10.1111/tra.12230
19. Watanabe, Y., Y. Tamura, S. Kawano, and T. Endo. 2015. Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria. Nat. Commun. 6:7922. http ://dx.doi.org/10.1038/ncomms8922