Optimization of adiponectin-derived peptides for inhibition of cancer cell growth and signaling

Biopolymers

Volumn 104, Issue 3, 2015, Pages 156-166

  Otvos, Laszlo ^a   Kovalszky, Ilona ^b   Olah, Julia ^b   Coroniti, Roberta ^c   Knappe, Daniel ^d   Nollmann, Friederike I ^d   Hoffmann, Ralf ^d   Wade, John D ^e   Lovas, Sandor ^f   Surmacz, Eva ^c  

^a Temple University   (United States)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c TEMPLE UNIVERSITY   (United States)

^d UNIVERSITY OF LEIPZIG   (Germany)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

activity relationships; biodistribution; breast cancer; chimera; chronic myeloid leukemia; growth inhibition; ophthalmic cell models; proteolytic stability; structure

Indexed keywords

DIMERS; DISEASES; HORMONES; METABOLISM; PEPTIDES; SIGNAL TRANSDUCTION; STRUCTURE (COMPOSITION);

BIODISTRIBUTIONS; BREAST CANCER; CELL MODEL; CHIMERA; CHRONIC MYELOID LEUKEMIAS; GROWTH INHIBITION; PROTEOLYTIC STABILITY;

CELL SIGNALING;

ADIPONECTIN; ADIPONECTIN RECEPTOR; ADIPONECTIN RECEPTOR AGONIST; ADP 355; ADP 400; ANTINEOPLASTIC AGENT; DIMER; GLYCINE; HORMONE RECEPTOR BLOCKING AGENT; LEPTIN; MONOMER; PEPTIDE DERIVATIVE; PROLINE; TYROSINE; UNCLASSIFIED DRUG; PEPTIDE;

ADULT; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BETA SHEET; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CHIMERA; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSTASIS; DRUG DESIGN; FEMALE; HALF LIFE TIME; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; HUMAN; K562 CELL LINE; MCF 7 CELL LINE; METABOLISM; NEOPLASMS; PATHOLOGY; SIGNAL TRANSDUCTION; SYNTHESIS;

ADIPONECTIN; CELL PROLIFERATION; HUMANS; K562 CELLS; MCF-7 CELLS; NEOPLASMS; PEPTIDES; SIGNAL TRANSDUCTION;

EID: 84979993247     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22627     Document Type: Article

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