Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch

Structure

Volumn 24, Issue 8, 2016, Pages 1380-1386

  Patel, Pryank ^a,b   Prescott, Gerald R ^a,c   Burgoyne, Robert D ^a   Lian, Lu Yun ^a   Morgan, Alan ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^c UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

adult onset neuronal lipofuscinosis; chaperone; DnaJ; Hsp40; neurodegeneration

Indexed keywords

CYSTEINE STRING PROTEIN; HEAT SHOCK COGNATE PROTEIN 70; PROTEIN DNAJ; UBIQUITIN PROTEIN LIGASE; DNAJ PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; HEAT SHOCK PROTEIN 40; HSPA8 PROTEIN, HUMAN; LYSINE; MEMBRANE PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN; SERINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; HUMAN; IN VITRO STUDY; NEUROTRANSMISSION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SURFACE CHARGE; ALPHA HELIX; BETA SHEET; BINDING SITE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; THERMODYNAMICS;

AMINO ACID MOTIFS; BINDING SITES; CLONING, MOLECULAR; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION; HSC70 HEAT-SHOCK PROTEINS; HSP40 HEAT-SHOCK PROTEINS; HUMANS; KINETICS; LYSINE; MEMBRANE PROTEINS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERINE; STRUCTURAL HOMOLOGY, PROTEIN; THERMODYNAMICS;

EID: 84979987518     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2016.06.009     Document Type: Article

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