Safety of D-β-hydroxybutyrate and melatonin for the treatment of hemorrhagic shock with Polytrauma

Shock

Volumn 44, Issue , 2015, Pages 79-89

  Wolf, Andrea ^a   Mulier, Kristine E ^a   Iyegha, Uroghupatei P ^a   Asghar, Javariah I ^a   Beilman, Gregory J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Antioxidant; Drug safety; Intraosseous infusion; Ischemia; Ketone bodies; Reperfusion; Resuscitation

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; DEXTRO BETA HYDROXYBUTYRIC ACID; HYDROXYBUTYRIC ACID; LACTATE DEHYDROGENASE; LACTIC ACID; MELATONIN; POTASSIUM; RINGER LACTATE SOLUTION; SODIUM; UNCLASSIFIED DRUG; 3 HYDROXYBUTYRIC ACID; CREATININE; PHOSPHOTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; EXPERIMENTAL HEMORRHAGIC SHOCK; FEMALE; HEART OUTPUT; HEART RATE; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; LACTATE BLOOD LEVEL; LIVER HEMORRHAGE; LIVER INJURY; LUNG CONTUSION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN ARTERIAL PRESSURE; MULTIPLE TRAUMA; NONHUMAN; PH; PIG; POTASSIUM BLOOD LEVEL; RESUSCITATION; SODIUM BLOOD LEVEL; SURVIVAL; UREA NITROGEN BLOOD LEVEL; ANIMAL; ARTERIAL PRESSURE; BLEEDING; CHEMISTRY; HEMODYNAMICS; INJURIES; LIVER; METABOLISM; SHOCK, HEMORRHAGIC; TIME FACTOR;

3-HYDROXYBUTYRIC ACID; ALANINE TRANSAMINASE; ANIMALS; ARTERIAL PRESSURE; ASPARTATE AMINOTRANSFERASES; BLOOD UREA NITROGEN; CARDIAC OUTPUT; CREATININE; FEMALE; HEART RATE; HEMODYNAMICS; HEMORRHAGE; L-LACTATE DEHYDROGENASE; LIVER; MALE; MELATONIN; MULTIPLE TRAUMA; PHOSPHOTRANSFERASES; SHOCK, HEMORRHAGIC; SWINE; TIME FACTORS;

EID: 84979833346     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000315     Document Type: Article

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