Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development

Antiviral Research

Volumn 133, Issue , 2016, Pages 41-49

  Yin, Yuebang ^a   Wang, Yijin ^a   Dang, Wen ^a   Xu, Lei ^a   Su, Junhong ^b   Zhou, Xinying ^a   Wang, Wenshi ^a   Felczak, Krzysztof ^c   van der Laan, Luc J W ^a   Pankiewicz, Krzysztof W ^c   van der Eijk, Annemiek A ^a   Bijvelds, Marcel ^a   Sprengers, Dave ^a   de Jonge, Hugo ^a   Koopmans, Marion P G ^a   Metselaar, Herold J ^a   Peppelenbosch, Maikel P ^a   Pan, Qiuwei ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Immunosuppressants; Intestinal organoids; Mycophenolic acid; Rotavirus

Indexed keywords

CYCLOPHILIN A; CYCLOPHILIN B; CYCLOSPORIN A; INOSINATE DEHYDROGENASE; MYCOPHENOLIC ACID; VIRUS RNA; ANTIVIRUS AGENT; GLUCOCORTICOID; GUANOSINE; IMMUNOSUPPRESSIVE AGENT;

ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; ARTICLE; CACO 2 CELL LINE; CASE REPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; INOCULATION; INTESTINAL TISSUE; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; RNA VIRUS; ROTAVIRUS; ROTAVIRUS INFECTION; VIRUS STRAIN; CACO-2 CELL LINE; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; INTESTINE; METABOLISM; TISSUE CULTURE TECHNIQUE; VIROLOGY; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CACO-2 CELLS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, VIRAL; GLUCOCORTICOIDS; GUANOSINE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINES; MYCOPHENOLIC ACID; ROTAVIRUS; ROTAVIRUS INFECTIONS; TISSUE CULTURE TECHNIQUES; VIRUS REPLICATION;

EID: 84979775148     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.07.017     Document Type: Article

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