Cyclosporin A Inhibits Rotavirus Replication and Restores Interferon-Beta Signaling Pathway In Vitro and In Vivo

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Shen, Zigang ^a   He, Haiyang ^a   Wu, Yuzhang ^a   Li, Jintao ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLOSPORIN A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 7; RIBAVIRIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTAVIRUS INFECTION; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELL LINE; CYCLOSPORINE; DIARRHEA; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HT29 CELLS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERFERON REGULATORY FACTORS; INTERFERON-BETA; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROTAVIRUS; ROTAVIRUS INFECTIONS; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; VIRUS REPLICATION;

EID: 84882734354     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071815     Document Type: Article

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