-
1
-
-
84920886150
-
Effects of various classes of antihypertensive drugs
-
Effects of blood pressure lowering on outcome incidence in hypertension 4. Overview and meta-Analyses
-
Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension 4. Effects of various classes of antihypertensive drugs. Overview and meta-Analyses. J Hypertens 2015; 33:195-211.
-
(2015)
J Hypertens
, vol.33
, pp. 195-211
-
-
Thomopoulos, C.1
Parati, G.2
Zanchetti, A.3
-
2
-
-
84940027793
-
Head-To-head comparisons of various classes of antihypertensive drugs. Overview and meta-Analyses
-
Effects of blood pressure lowering on outcome incidence in hypertension 5
-
Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension 5. Head-To-head comparisons of various classes of antihypertensive drugs. Overview and meta-Analyses. J Hypertens 2015; 33:1321-1341.
-
(2015)
J Hypertens
, vol.33
, pp. 1321-1341
-
-
Thomopoulos, C.1
Parati, G.2
Zanchetti, A.3
-
3
-
-
84969915745
-
Effects of blood pressure lowering on outcome incidence in hypertension. 8. Outcome reductions versus discontinuations because of adverse drug events-meta-Analyses of randomized trials
-
Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension. 8. Outcome reductions versus discontinuations because of adverse drug events-meta-Analyses of randomized trials. J Hypertens 2016; 34:1451-1463.
-
(2016)
J Hypertens
, vol.34
, pp. 1451-1463
-
-
Thomopoulos, C.1
Parati, G.2
Zanchetti, A.3
-
4
-
-
84927786388
-
Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, metaanalyses and meta-regression analyses of randomized trials
-
Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, metaanalyses and meta-regression analyses of randomized trials. J Hypertens 2014; 32:2285-2295.
-
(2014)
J Hypertens
, vol.32
, pp. 2285-2295
-
-
Thomopoulos, C.1
Parati, G.2
Zanchetti, A.3
-
5
-
-
84960411883
-
Effects of blood pressure lowering on outcome incidence in hypertension. 7. Effects of more versus less intensive blood pressure lowering and different achieved blood pressure levels-updated overview and meta-Analyses of randomized trials
-
Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension. 7. Effects of more versus less intensive blood pressure lowering and different achieved blood pressure levels-updated overview and meta-Analyses of randomized trials. J Hypertens 2016; 34:613-622.
-
(2016)
J Hypertens
, vol.34
, pp. 613-622
-
-
Thomopoulos, C.1
Parati, G.2
Zanchetti, A.3
-
6
-
-
84921009356
-
The Australian therapeutic trial in mild hypertension
-
Management Committee
-
Management Committee. The Australian therapeutic trial in mild hypertension. Lancet 1980; 315:1261-1267.
-
(1980)
Lancet
, vol.315
, pp. 1261-1267
-
-
-
7
-
-
42949112210
-
Treatment of hypertension in patients 80 years of age or older
-
Beckett NS, Peters R, Fletcher AE, Staessen JA, Liu L, Dumitrascu D, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008; 358:1887-1898.
-
(2008)
N Engl J Med
, vol.358
, pp. 1887-1898
-
-
Beckett, N.S.1
Peters, R.2
Fletcher, A.E.3
Staessen, J.A.4
Liu, L.5
Dumitrascu, D.6
-
8
-
-
0021863832
-
MRC trial on treatment of mild hypertension: Principal results
-
Medical Research Council Working Party
-
Medical Research Council Working Party. MRC trial on treatment of mild hypertension: principal results. Br Med J 1985; 291:97-104.
-
(1985)
Br Med J
, vol.291
, pp. 97-104
-
-
-
9
-
-
0026512315
-
Medical Research Council trial of treatment of hypertension in older adults: Principal results
-
MRC Working Party
-
MRC Working Party. Medical Research Council trial of treatment of hypertension in older adults: principal results. Br Med J 1992; 304:405-412.
-
(1992)
Br Med J
, vol.304
, pp. 405-412
-
-
-
10
-
-
0019197138
-
Treatment of mild hypertension: A five year controlled drug trial
-
Helgeland A. Treatment of mild hypertension: A five year controlled drug trial. The Oslo study. Am J Med 1980; 69:725-732.
-
(1980)
The Oslo Study. Am J Med
, vol.69
, pp. 725-732
-
-
Helgeland, A.1
-
11
-
-
0025831464
-
Final results of the Systolic Hypertension in the Elderly Program (SHEP)
-
SHEP Co-operative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension
-
SHEP Co-operative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991; 265:3255-3264.
-
(1991)
JAMA
, vol.265
, pp. 3255-3264
-
-
-
12
-
-
0022469583
-
Randomised trial of treatment of hypertension in elderly patients in primary care
-
Coope J, Warrender TS. Randomised trial of treatment of hypertension in elderly patients in primary care. BMJ 1986; 293:1145-1151.
-
(1986)
BMJ
, vol.293
, pp. 1145-1151
-
-
Coope, J.1
Warrender, T.S.2
-
13
-
-
0002358551
-
Atenolol in secondary prevention after stroke
-
For the TEST (Tenormin after Stroke and TIA) Study Group.
-
Eriksson S, Olofsson B-O, Wester P-O, For the TEST (Tenormin after Stroke and TIA) Study Group. Atenolol in secondary prevention after stroke. Cerebrovasc Dis 1995; 5:21-25.
-
(1995)
Cerebrovasc Dis
, vol.5
, pp. 21-25
-
-
Eriksson, S.1
Olofsson, B.-O.2
Wester, P.-O.3
-
14
-
-
4544304433
-
Effect of long-Acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): Randomised controlled trial
-
Poole-Wilson PA, Lubsen J, Kirwan BA, van Dalen FJ, Wagener G, Danchin N, et al. Effect of long-Acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): Randomised controlled trial. Lancet 2004; 364:849-857.
-
(2004)
Lancet
, vol.364
, pp. 849-857
-
-
Poole-Wilson, P.A.1
Lubsen, J.2
Kirwan, B.A.3
Van Dalen, F.J.4
Wagener, G.5
Danchin, N.6
-
15
-
-
7744231805
-
Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: The CAMELOT study: A randomized controlled trial
-
Nissen SE, Tuzcu EM, Libby P, Thompson PD, Ghali M, Garza D, et al. Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: The CAMELOT study: A randomized controlled trial. JAMA 2004; 292:2217-2225.
-
(2004)
JAMA
, vol.292
, pp. 2217-2225
-
-
Nissen, S.E.1
Tuzcu, E.M.2
Libby, P.3
Thompson, P.D.4
Ghali, M.5
Garza, D.6
-
16
-
-
0036892151
-
Effects of amlodipine fosinopril combination on microalbuminuria in hypertensive type 2 diabetic patients
-
Fogari R, Preti P, Zoppi A, Rinaldi A, Corradi L, Pasotti C, et al. Effects of amlodipine fosinopril combination on microalbuminuria in hypertensive type 2 diabetic patients. Am J Hypertens 2002; 15:1042-1049.
-
(2002)
Am J Hypertens
, vol.15
, pp. 1042-1049
-
-
Fogari, R.1
Preti, P.2
Zoppi, A.3
Rinaldi, A.4
Corradi, L.5
Pasotti, C.6
-
17
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345:851-860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
Berl, T.4
Pohl, M.A.5
Lewis, J.B.6
-
18
-
-
0042167444
-
Long term effects of nisoldipine on the progression of coronary atherosclerosis and the occurrence of clinical events: The NICOLE study
-
Dens JA, Desmet WJ, Coussement P, De Scheerder IK, Kostopoulos K, Kerdsinchai P, et al. Long term effects of nisoldipine on the progression of coronary atherosclerosis and the occurrence of clinical events: The NICOLE study. Heart 2003; 89:887-892.
-
(2003)
Heart
, vol.89
, pp. 887-892
-
-
Dens, J.A.1
Desmet, W.J.2
Coussement, P.3
De Scheerder, I.K.4
Kostopoulos, K.5
Kerdsinchai, P.6
-
19
-
-
15844414184
-
Blood-pressure control for renoprotection in patients with nondiabetic chronic renal disease (REIN-2): Multicentre, randomized controlled trial
-
Ruggenenti P, Perna A, Loriga G, Ganeva M, Ene-Iordache B, Turturro M, et al. Blood-pressure control for renoprotection in patients with nondiabetic chronic renal disease (REIN-2): multicentre, randomized controlled trial. Lancet 2005; 365:939-946.
-
(2005)
Lancet
, vol.365
, pp. 939-946
-
-
Ruggenenti, P.1
Perna, A.2
Loriga, G.3
Ganeva, M.4
Ene-Iordache, B.5
Turturro, M.6
-
20
-
-
15844368318
-
Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency
-
The Angiotensin-Converting-Enzyme Inhibition in Progressive Renal Insufficiency Study Group
-
Maschio G, Alberti D, Janin G, Locatelli F, Mann JFE, Motolese M, et al. Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. The Angiotensin-Converting-Enzyme Inhibition in Progressive Renal Insufficiency Study Group. N Engl J Med 1996; 334:939-945.
-
(1996)
N Engl J Med
, vol.334
, pp. 939-945
-
-
Maschio, G.1
Alberti, D.2
Janin, G.3
Locatelli, F.4
Mann, J.F.E.5
Motolese, M.6
-
21
-
-
7444221237
-
Preventing microalbuminuria in type 2 diabetes
-
Bergamo Nephrologic Diabetes Complications Trial (BENEDICT) Investigators
-
Ruggenenti P, Fassi A, Ilieva AP, Bruno S, Iliev IP, Brusegan V, et al., Bergamo Nephrologic Diabetes Complications Trial (BENEDICT) Investigators. Preventing microalbuminuria in type 2 diabetes. N Engl J Med 2004; 351:1941-1951.
-
(2004)
N Engl J Med
, vol.351
, pp. 1941-1951
-
-
Ruggenenti, P.1
Fassi, A.2
Ilieva, A.P.3
Bruno, S.4
Iliev, I.P.5
Brusegan, V.6
-
22
-
-
1442323586
-
Effects of low dose ramipril on cardiovascular and renal outcomes in patients with type 2 diabetes and raised excretion of urinary albumin: Randomised, double blind, placebo controlled trial (the DIABHYCAR study)
-
DIABHYCAR Study Investigators
-
Marre M, Lievre M, Chatellier G, Mann JF, Passa P, Ménard J, DIABHYCAR Study Investigators. Effects of low dose ramipril on cardiovascular and renal outcomes in patients with type 2 diabetes and raised excretion of urinary albumin: Randomised, double blind, placebo controlled trial (the DIABHYCAR study). BMJ 2004; 328:495.
-
(2004)
BMJ
, vol.328
, pp. 495
-
-
Marre, M.1
Lievre, M.2
Chatellier, G.3
Mann, J.F.4
Passa, P.5
Ménard, J.6
-
23
-
-
48649107300
-
Effects of Ramipril and Rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: Results of the Diabetes reduction assessment with Ramipril and Rosiglitazone medication (DREAM) trial
-
DREAM Trial Investigators
-
DREAM Trial Investigators. Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: Results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabetes Care 2008; 31:1007-1014.
-
(2008)
Diabetes Care
, vol.31
, pp. 1007-1014
-
-
-
24
-
-
0034688194
-
Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
-
The Heart Outcomes Prevention Evaluation Study Investigators
-
The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000; 342:145-153.
-
(2000)
N Engl J Med
, vol.342
, pp. 145-153
-
-
-
25
-
-
0027517659
-
The effect of angiotensin converting-enzyme inhibition on diabetic nephropathy
-
The Collaborative Study Group
-
Lewis EJ, Hunsicker LG, Bain RP, Rohde RD, The Collaborative Study Group. The effect of angiotensin converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329:1456-1462.
-
(1993)
N Engl J Med
, vol.329
, pp. 1456-1462
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Bain, R.P.3
Rohde, R.D.4
-
26
-
-
19644400972
-
Angiotensin-converting-enzyme inhibition in stable coronary artery disease
-
The PEACE Trial Investigators
-
The PEACE Trial Investigators.Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med 2004; 351:2058-2068.
-
(2004)
N Engl J Med
, vol.351
, pp. 2058-2068
-
-
-
27
-
-
53749108177
-
Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): A randomised placebo-controlled trial
-
Sjølie AK, Klein R, Porta M, Orchard T, Fuller J, Parving HH, et al. Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): A randomised placebo-controlled trial. Lancet 2008; 372:1385-1393.
-
(2008)
Lancet
, vol.372
, pp. 1385-1393
-
-
Sjølie, A.K.1
Klein, R.2
Porta, M.3
Orchard, T.4
Fuller, J.5
Parving, H.H.6
-
28
-
-
64749085587
-
Valsartan for prevention of recurrent atrial fibrillation
-
The GISSI-AF Investigators
-
The GISSI-AF Investigators. Valsartan for prevention of recurrent atrial fibrillation. N Engl J Med 2009; 360:1606-1617.
-
(2009)
N Engl J Med
, vol.360
, pp. 1606-1617
-
-
-
29
-
-
57349142933
-
Irbesartan in patients with heart failure and preserved ejection fraction
-
Massie BM, Carson PE, McMurray JJ, Komajda M, McKelvie R, Zile MR, et al. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med 2008; 359:2456-2467.
-
(2008)
N Engl J Med
, vol.359
, pp. 2456-2467
-
-
Massie, B.M.1
Carson, P.E.2
McMurray, J.J.3
Komajda, M.4
McKelvie, R.5
Zile, M.R.6
-
30
-
-
0035922444
-
The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
-
Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group
-
Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P, Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345:870-878.
-
(2001)
N Engl J Med
, vol.345
, pp. 870-878
-
-
Parving, H.H.1
Lehnert, H.2
Bröchner-Mortensen, J.3
Gomis, R.4
Andersen, S.5
Arner, P.6
-
31
-
-
77951453096
-
Effect of valsartan on the incidence of diabetes and cardiovascular events
-
The NAVIGATOR Study Group
-
The NAVIGATOR Study Group. Effect of valsartan on the incidence of diabetes and cardiovascular events. N Eng J Med 2010; 362:1477-1490.
-
(2010)
N Eng J Med
, vol.362
, pp. 1477-1490
-
-
-
32
-
-
82455162519
-
Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: A multicentre, randomised, placebo-controlled study
-
For the ORIENT Study Investigators.
-
Imai E, Chan JC, Ito S, Yamasaki T, Kobayashi F, Haneda M, Makino H, For the ORIENT Study Investigators. Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: A multicentre, randomised, placebo-controlled study. Diabetologia 2011; 54:2978-2986.
-
(2011)
Diabetologia
, vol.54
, pp. 2978-2986
-
-
Imai, E.1
Chan, J.C.2
Ito, S.3
Yamasaki, T.4
Kobayashi, F.5
Haneda, M.6
Makino, H.7
-
33
-
-
52249116778
-
Telmisartan to prevent recurrent stroke and cardiovascular events
-
Yusuf S, Diener HC, Sacco RL, Cotton D, Ôunpuu S, Lawton WA, et al. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med 2008; 359:1225-1237.
-
(2008)
N Engl J Med
, vol.359
, pp. 1225-1237
-
-
Yusuf, S.1
Diener, H.C.2
Sacco, R.L.3
Cotton, D.4
Ôunpuu, S.5
Lawton, W.A.6
-
34
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345:861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
De Zeeuw, D.3
Keane, W.F.4
Mitch, W.E.5
Parving, H.H.6
-
35
-
-
79952373965
-
Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
-
ROADMAP Trial Investigators
-
Haller H, Ito S, Izzo JL Jr, Januszewicz A, Katayama S, Menne J, et al., ROADMAP Trial Investigators. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364:907-917.
-
(2011)
N Engl J Med
, vol.364
, pp. 907-917
-
-
Haller, H.1
Ito, S.2
Izzo, J.L.3
Januszewicz, A.4
Katayama, S.5
Menne, J.6
-
36
-
-
0037534905
-
The Study on Cognition and Prognosis in the Elderly (SCOPE): Principal results of a randomized double-blind intervention trial
-
Lithell H, Hansson L, Skoog I, Elmfeldt D, Hofman A, Olofsson B, et al. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 2003; 21:875-886.
-
(2003)
J Hypertens
, vol.21
, pp. 875-886
-
-
Lithell, H.1
Hansson, L.2
Skoog, I.3
Elmfeldt, D.4
Hofman, A.5
Olofsson, B.6
-
37
-
-
53049109468
-
Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled tria
-
Telmisartan Randomized Assessment Study in ACE intolerant subjects with cardiovascular disease (TRANSCEND) Investigators.l
-
Telmisartan Randomized Assessment Study in ACE intolerant subjects with cardiovascular disease (TRANSCEND) Investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial. Lancet 2008; 372:1174-1183.
-
(2008)
Lancet
, vol.372
, pp. 1174-1183
-
-
-
38
-
-
0015786754
-
Control of moderately raised blood pressure. Report of a co-operative randomized controlled trial
-
Barraclough M, Bainton D, Cochrane AL. Control of moderately raised blood pressure. Report of a co-operative randomized controlled trial. BMJ 1973; 3:434-436.
-
(1973)
BMJ
, vol.3
, pp. 434-436
-
-
Barraclough, M.1
Bainton, D.2
Cochrane, A.L.3
-
39
-
-
0014935696
-
Hypotensive therapy in stroke survivors
-
Carter BA. Hypotensive therapy in stroke survivors. Lancet 1970; 295:485-489.
-
(1970)
Lancet
, vol.295
, pp. 485-489
-
-
Carter, B.A.1
-
40
-
-
0016258143
-
Effect of antihypertensive treatment on stroke recurrence
-
Hypertension-Stroke Cooperative Study Group
-
Hypertension-Stroke Cooperative Study Group. Effect of antihypertensive treatment on stroke recurrence. JAMA 1974; 229:409-418.
-
(1974)
JAMA
, vol.229
, pp. 409-418
-
-
-
41
-
-
0019403371
-
Blood pressure reduction in elderly: A randomised controlled trial of methyldopa
-
Sprackling ME, Mitchell JR, Short AH, Watt G. Blood pressure reduction in elderly: A randomised controlled trial of methyldopa. BMJ 1981; 283:1151-1153.
-
(1981)
BMJ
, vol.283
, pp. 1151-1153
-
-
Sprackling, M.E.1
Mitchell, J.R.2
Short, A.H.3
Watt, G.4
-
42
-
-
0017387956
-
Treatment of mild hypertension: Results of a ten-year intervention trial
-
Smith WM. Treatment of mild hypertension: Results of a ten-year intervention trial. Circ Res 1977; 40:98-105.
-
(1977)
Circ Res
, vol.40
, pp. 98-105
-
-
Smith, W.M.1
-
43
-
-
0014952910
-
Results in patients with diastolic blood pressures averaging 90 through 114mm Hg
-
Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment on morbidity in hypertension
-
Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 90 through 114mm Hg. JAMA 1970; 213:1143-1152.
-
(1970)
JAMA
, vol.213
, pp. 1143-1152
-
-
-
44
-
-
79960591166
-
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: A randomized controlled trial
-
Matsuzaki M, Ogihara T, Umemoto S, Rakugi H, Matsuoka H, Shimada K, et al. Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: A randomized controlled trial. J Hypertens 2011; 29:1649-1659.
-
(2011)
J Hypertens
, vol.29
, pp. 1649-1659
-
-
Matsuzaki, M.1
Ogihara, T.2
Umemoto, S.3
Rakugi, H.4
Matsuoka, H.5
Shimada, K.6
-
45
-
-
0023433489
-
Beta-blockers versus diuretics in hypertensive men: Main results from the HAPPHY trial
-
Wilhelmsen L, Berglund G, Elmfeldt D, Fitzsimons T, Holzgreve H, Hosie J, et al. Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. J Hypertens 1987; 5:561-572.
-
(1987)
J Hypertens
, vol.5
, pp. 561-572
-
-
Wilhelmsen, L.1
Berglund, G.2
Elmfeldt, D.3
Fitzsimons, T.4
Holzgreve, H.5
Hosie, J.6
-
46
-
-
0022254994
-
Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: The International Prospective Primary Prevention Study in Hypertension (IPPPSH)
-
The IPPPSH Collaborative Groups
-
The IPPPSH Collaborative Groups. Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker oxprenolol: The International Prospective Primary Prevention Study in Hypertension (IPPPSH). J Hypertens 1985; 3:379-392.
-
(1985)
J Hypertens
, vol.3
, pp. 379-392
-
-
-
47
-
-
0019954662
-
Results of long-Term therapy
-
Veterans Administration Cooperative Study Group on Antihypertensive Agents. Comparison of propranolol and hydrochlorothiazide for the initial treatment of hypertension. II
-
Veterans Administration Cooperative Study Group on Antihypertensive Agents. Comparison of propranolol and hydrochlorothiazide for the initial treatment of hypertension. II. Results of long-Term therapy. JAMA 1982; 248:2004-2011.
-
(1982)
JAMA
, vol.248
, pp. 2004-2011
-
-
-
48
-
-
57349138291
-
Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients
-
Jamerson K, Weber MA, Bakris GL, Dahlöf B, Pitt B, Shi V, et al. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med 2008; 359:2417-2428.
-
(2008)
N Engl J Med
, vol.359
, pp. 2417-2428
-
-
Jamerson, K.1
Weber, M.A.2
Bakris, G.L.3
Dahlöf, B.4
Pitt, B.5
Shi, V.6
-
49
-
-
0344373794
-
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker Vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288:2981-2997.
-
(2002)
JAMA
, vol.288
, pp. 2981-2997
-
-
-
50
-
-
84920533602
-
COLM Investigators. Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: A randomized, controlled trial
-
Ogihara T, Saruta T, Rakugi H, Saito I, Shimamoto K, Matsuoka H, et al., COLM Investigators. Combinations of olmesartan and a calcium channel blocker or a diuretic in elderly hypertensive patients: A randomized, controlled trial. J Hypertens 2014; 32:2054-2063.
-
(2014)
J Hypertens
, vol.32
, pp. 2054-2063
-
-
Ogihara, T.1
Saruta, T.2
Rakugi, H.3
Saito, I.4
Shimamoto, K.5
Matsuoka, H.6
-
51
-
-
0034729993
-
Morbidity and mortality in patients randomised to double-blind treatment with a long-Acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT)
-
Brown MJ, Palmer CR, Castaigne A, de Leeuw PW, Mancia G, Rosenthal T, et al. Morbidity and mortality in patients randomised to double-blind treatment with a long-Acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 2000; 356:366-372.
-
(2000)
Lancet
, vol.356
, pp. 366-372
-
-
Brown, M.J.1
Palmer, C.R.2
Castaigne, A.3
De Leeuw, P.W.4
Mancia, G.5
Rosenthal, T.6
-
52
-
-
9544225173
-
A randomized controlled trial
-
Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS
-
Borhani NO, Mercuri M, Borhani PA, Buckalew VM, Canossa-Terris M, Carr AA, et al. Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). A randomized controlled trial. JAMA 1996; 276:785-791.
-
(1996)
JAMA
, vol.276
, pp. 785-791
-
-
Borhani, N.O.1
Mercuri, M.2
Borhani, P.A.3
Buckalew, V.M.4
Canossa-Terris, M.5
Carr, A.A.6
-
53
-
-
0032748510
-
Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives
-
National Intervention Cooperative Study in Elderly Hypertensives Study Group
-
National Intervention Cooperative Study in Elderly Hypertensives Study Group. Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives. Hypertension 1999; 34:1129-1133.
-
(1999)
Hypertension
, vol.34
, pp. 1129-1133
-
-
-
54
-
-
3843080677
-
Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: The NESTOR Study
-
Marre M, Puig JG, Kokot F, Fernandez M, Jermendy G, Opie L, et al. Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: The NESTOR Study. J Hypertens 2004; 22:1613-1622.
-
(2004)
J Hypertens
, vol.22
, pp. 1613-1622
-
-
Marre, M.1
Puig, J.G.2
Kokot, F.3
Fernandez, M.4
Jermendy, G.5
Opie, L.6
-
55
-
-
0037145856
-
Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: Results from the AASK trial
-
Wright JT Jr, Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, et al. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: Results from the AASK trial. JAMA 2002; 288:2421-2431.
-
(2002)
JAMA
, vol.288
, pp. 2421-2431
-
-
Wright, J.T.1
Bakris, G.2
Greene, T.3
Agodoa, L.Y.4
Appel, L.J.5
Charleston, J.6
-
56
-
-
24644443331
-
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial
-
Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial. Lancet 2005; 366:895-906.
-
(2005)
Lancet
, vol.366
, pp. 895-906
-
-
Dahlöf, B.1
Sever, P.S.2
Poulter, N.R.3
Wedel, H.4
Beevers, D.G.5
Caulfield, M.6
-
57
-
-
0037027501
-
Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis: Principal results of the European Lacidipine Study on Atherosclerosis (ELSA), a randomized, double-blind, long-Term trial
-
Zanchetti A, Bond MG, Hennig M, Neiss A, Mancia G, Dal Palù C, et al. Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis: principal results of the European Lacidipine Study on Atherosclerosis (ELSA), a randomized, double-blind, long-Term trial. Circulation 2002; 106:2422-2427.
-
(2002)
Circulation
, vol.106
, pp. 2422-2427
-
-
Zanchetti, A.1
Bond, M.G.2
Hennig, M.3
Neiss, A.4
Mancia, G.5
Dal, P.C.6
-
58
-
-
0345492460
-
The international verapamil-trandolapril study (INVEST): A randomized controlled trial
-
A calcium antagonist vs a noncalcium antagonist hypertension treatment strategy for patients with coronary artery disease
-
Pepine CJ, Handberg EM, Cooper-DeHoff RM, Marks RG, Kowey P, Messerli FH, et al. A calcium antagonist vs a noncalcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial. JAMA 2003; 290:2805-2816.
-
(2003)
JAMA
, vol.290
, pp. 2805-2816
-
-
Pepine, C.J.1
Handberg, E.M.2
Cooper-DeHoff, R.M.3
Marks, R.G.4
Kowey, P.5
Messerli, F.H.6
-
59
-
-
0032511601
-
Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39
-
UK Prospective Diabetes Study Group
-
UK Prospective Diabetes Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 39. BMJ 1998; 317:713-720.
-
(1998)
BMJ
, vol.317
, pp. 713-720
-
-
-
60
-
-
0037160968
-
Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
-
Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol. Lancet 2002; 359:995-1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlöf, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
Julius, S.4
Beevers, G.5
De Faire, U.6
-
61
-
-
0032485350
-
The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with noninsulin-dependent diabetes and hypertension
-
Estacio RO, Jeffers BW, Hiatt WR, Biggerstaff SL, Gifford N, Schrier RW. The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with noninsulin-dependent diabetes and hypertension. N Engl J Med 1998; 338:645-652.
-
(1998)
N Engl J Med
, vol.338
, pp. 645-652
-
-
Estacio, R.O.1
Jeffers, B.W.2
Hiatt, W.R.3
Biggerstaff, S.L.4
Gifford, N.5
Schrier, R.W.6
-
62
-
-
0031944128
-
Outcome results of the fosinopril Versus amlodipine Cardiovascular Events Randomized Trial (FACET) in patients with hypertension and NIDDM
-
Tatti P, Pahor M, Byington RP, Di Mauro P, Guarisco R, Strollo G, et al. Outcome results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET) in patients with hypertension and NIDDM. Diab Care 1998; 21:597-603.
-
(1998)
Diab Care
, vol.21
, pp. 597-603
-
-
Tatti, P.1
Pahor, M.2
Byington, R.P.3
Di Mauro, P.4
Guarisco, R.5
Strollo, G.6
-
63
-
-
11144355108
-
Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: The Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial
-
Yui Y, Sumiyoshi T, Kodama K, Hirayama A, Nonogi H, Kanmatsuse K, et al. Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: The Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial. Hypertens Res 2004; 27:181-191.
-
(2004)
Hypertens Res
, vol.27
, pp. 181-191
-
-
Yui, Y.1
Sumiyoshi, T.2
Kodama, K.3
Hirayama, A.4
Nonogi, H.5
Kanmatsuse, K.6
-
64
-
-
0034750970
-
Nifedipine and enalapril equally reduce the progression of nephropathy in hypertensive type 2 diabetics
-
J-MIND Study Group
-
Baba S, J-MIND Study Group. Nifedipine and enalapril equally reduce the progression of nephropathy in hypertensive type 2 diabetics. Diabetes Res Clin Pract 2001; 54:191-201.
-
(2001)
Diabetes Res Clin Pract
, vol.54
, pp. 191-201
-
-
Baba, S.1
-
65
-
-
38549181561
-
Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: Candesartan antihypertensive survival evaluation in Japan trial
-
Ogihara T, Nakao K, Fukui T, Fukiyama K, Ueshima K, Oba K, et al. Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: candesartan antihypertensive survival evaluation in Japan trial. Hypertension 2008; 51:393-398.
-
(2008)
Hypertension
, vol.51
, pp. 393-398
-
-
Ogihara, T.1
Nakao, K.2
Fukui, T.3
Fukiyama, K.4
Ueshima, K.5
Oba, K.6
-
66
-
-
84857634811
-
Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: Nagoya HEART Study
-
Muramatsu T, Matsushita K, Yamashita K, Kondo T, Maeda K, Shintani S, et al. Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study. Hypertension 2012; 59:580-586.
-
(2012)
Hypertension
, vol.59
, pp. 580-586
-
-
Muramatsu, T.1
Matsushita, K.2
Yamashita, K.3
Kondo, T.4
Maeda, K.5
Shintani, S.6
-
67
-
-
2942635317
-
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised tria1
-
Julius S, Kjeldsen SE, Weber M, Brunner HR, Ekman S, Hansson L, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial. Lancet 2004; 363:2022-2031.
-
(2004)
Lancet
, vol.363
, pp. 2022-2031
-
-
Julius, S.1
Kjeldsen, S.E.2
Weber, M.3
Brunner, H.R.4
Ekman, S.5
Hansson, L.6
-
68
-
-
0037851836
-
Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial
-
Black HR, Elliott WJ, Grandits G, Grambsch P, Lucente T, White WB, et al. Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial. JAMA 2003; 289:2073-2082.
-
(2003)
JAMA
, vol.289
, pp. 2073-2082
-
-
Black, H.R.1
Elliott, W.J.2
Grandits, G.3
Grambsch, P.4
Lucente, T.5
White, W.B.6
-
69
-
-
7444237666
-
Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy
-
Barnett AH, Bain SC, Bouter P, Karlberg B, Madsbad S, Jervell J, et al. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 2004; 351:1952-1961.
-
(2004)
N Engl J Med
, vol.351
, pp. 1952-1961
-
-
Barnett, A.H.1
Bain, S.C.2
Bouter, P.3
Karlberg, B.4
Madsbad, S.5
Jervell, J.6
-
70
-
-
42049107348
-
Telmisartan, ramipril, or both in patients at high risk for vascular events
-
ONTARGET Investigators
-
ONTARGET Investigators. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008; 358:1547-1559.
-
(2008)
N Engl J Med
, vol.358
, pp. 1547-1559
-
-
-
71
-
-
34249897487
-
Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: A randomized controlled study of benazepril and losartan in chronic renal insufficiency
-
Hou FF, Xie D, Zhang X, Chen PY, Zhang WR, Liang M, et al. Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: A randomized controlled study of benazepril and losartan in chronic renal insufficiency. J Am Soc Nephrol 2007; 18:1889-1898.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1889-1898
-
-
Hou, F.F.1
Xie, D.2
Zhang, X.3
Chen, P.Y.4
Zhang, W.R.5
Liang, M.6
-
72
-
-
0033620788
-
Renoprotective properties of ACE-inhibition in nondiabetic nephropathies with nonnephrotic proteinuria
-
Ruggenenti P, Perna A, Gherardi G, Garini G, Zoccali C, Salvadori M, et al. Renoprotective properties of ACE-inhibition in nondiabetic nephropathies with nonnephrotic proteinuria. Lancet 1999; 354:359-364.
-
(1999)
Lancet
, vol.354
, pp. 359-364
-
-
Ruggenenti, P.1
Perna, A.2
Gherardi, G.3
Garini, G.4
Zoccali, C.5
Salvadori, M.6
-
73
-
-
0030604561
-
Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, nondiabetic nephropathy
-
The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia)
-
The GISEN Group (Gruppo Italiano di Studi Epidemiologici in Nefrologia). Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, nondiabetic nephropathy. Lancet 1997; 349:1857-1863.
-
(1997)
Lancet
, vol.349
, pp. 1857-1863
-
-
-
74
-
-
66249127233
-
Angiotensin II receptor blocker-based vs. Nonangiotensin II receptor blocker-based therapy in patients with angiographically documented coronary artery disease and hypertension: The heart institute of Japan candesartan randomized trial for evaluation in coronary artery disease (HIJ-CREATE)
-
Kasanuki H, Hagiwara N, Hosoda S, Sumiyoshi T, Honda T, Haze K, et al. Angiotensin II receptor blocker-based vs. nonangiotensin II receptor blocker-based therapy in patients with angiographically documented coronary artery disease and hypertension: The Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease (HIJ-CREATE). Eur Heart J 2009; 30:1203-1212.
-
(2009)
Eur Heart J
, vol.30
, pp. 1203-1212
-
-
Kasanuki, H.1
Hagiwara, N.2
Hosoda, S.3
Sumiyoshi, T.4
Honda, T.5
Haze, K.6
-
75
-
-
0036672238
-
A population-based European cohort study of persistence in newly diagnosed hypertensive patients
-
Hasford J, Mimran A, Simon WR. A population-based European cohort study of persistence in newly diagnosed hypertensive patients. J Hum Hypertens 2002; 156:569-575.
-
(2002)
J Hum Hypertens
, vol.156
, pp. 569-575
-
-
Hasford, J.1
Mimran, A.2
Simon, W.R.3
-
76
-
-
23644449243
-
Persistence and discontinuation patterns of antihypertensive therapy among newly treated patients: A population-based study
-
Bourgault C, Sénécal M, Brisson M, Marentette MA, Gregiore J-P. Persistence and discontinuation patterns of antihypertensive therapy among newly treated patients: A population-based study. J Hum Hypertens 2005; 19:607-613.
-
(2005)
J Hum Hypertens
, vol.19
, pp. 607-613
-
-
Bourgault, C.1
Sénécal, M.2
Brisson, M.3
Marentette, M.A.4
Gregiore, J.-P.5
-
77
-
-
33646835918
-
Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice
-
Burke TA, Sturkenboom MC, Lu SE, Wentworth CE, Lin Y, Rhoads GG. Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice. J Hypertens 2005; 24:1193-1200.
-
(2005)
J Hypertens
, vol.24
, pp. 1193-1200
-
-
Burke, T.A.1
Sturkenboom, M.C.2
Lu, S.E.3
Wentworth, C.E.4
Lin, Y.5
Rhoads, G.G.6
-
78
-
-
40449097623
-
Discontinuation of and changes in drug therapy for hypertension among newly-Treated patient: A population-based study in Italy
-
Corrao G, Zambon A, Parodi A, Poluzzi E, Baldi I, Merlino L, et al. Discontinuation of and changes in drug therapy for hypertension among newly-Treated patient: A population-based study in Italy. J Hypertens 2008; 26:819-824.
-
(2008)
J Hypertens
, vol.26
, pp. 819-824
-
-
Corrao, G.1
Zambon, A.2
Parodi, A.3
Poluzzi, E.4
Baldi, I.5
Merlino, L.6
-
79
-
-
84880015206
-
2013 ESH/ESC Guidelines for the management of arterial hypertension
-
The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC
-
Mancia G, Fagard R, Narkiewicz K, Redón J, Zanchetti A, Böhm M, et al. The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). 2013 ESH/ESC Guidelines for the management of arterial hypertension. J Hypertens 2013; 31:1281-1357.
-
(2013)
J Hypertens
, vol.31
, pp. 1281-1357
-
-
Mancia, G.1
Fagard, R.2
Narkiewicz, K.3
Redón, J.4
Zanchetti, A.5
Böhm, M.6
|