1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2)

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 17, 2016, Pages 4330-4333

  Röhrig, Ute F ^a   Majjigapu, Somi Reddy ^a,b   Caldelari, Daniela ^a   Dilek, Nahzli ^a   Reichenbach, Patrick ^c   Ascencao, Kelly ^a   Irving, Melita ^c   Coukos, George ^c,d   Vogel, Pierre ^b,c   Zoete, Vincent ^a   Michielin, Olivier ^a,c,d  

^a SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^b EPFL   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Cancer immunotherapy; Cellular assays; Indoleamine 2,3 dioxygenase; Molecular modeling; Tryptophan metabolism

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; ENZYME INHIBITOR; INDOLEAMINE 2,3 DIOXYGENASE; TRIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG SELECTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC50; MOLECULAR PROBE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; SYNTHESIS;

CATALYTIC DOMAIN; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INHIBITORY CONCENTRATION 50; MOLECULAR WEIGHT; TRIAZOLES;

EID: 84979656041     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2016.07.031     Document Type: Article

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