-
1
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
1 ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489 (2012), 57–74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
2
-
-
84875275808
-
On the immortality of television sets: “function” in the human genome according to the evolution-free gospel of ENCODE
-
2 Graur, D., et al. On the immortality of television sets: “function” in the human genome according to the evolution-free gospel of ENCODE. Genome Biol. Evol. 5 (2013), 578–590.
-
(2013)
Genome Biol. Evol.
, vol.5
, pp. 578-590
-
-
Graur, D.1
-
3
-
-
84876031068
-
The ENCODE project: missteps overshadowing a success
-
3 Eddy, S.R., The ENCODE project: missteps overshadowing a success. Curr. Biol. 23 (2013), R259–R261.
-
(2013)
Curr. Biol.
, vol.23
, pp. R259-R261
-
-
Eddy, S.R.1
-
4
-
-
84905455429
-
8.2% of the human genome is constrained: variation in rates of turnover across functional element classes in the human lineage
-
4 Rands, C.M., et al. 8.2% of the human genome is constrained: variation in rates of turnover across functional element classes in the human lineage. PLoS Genet., 10, 2014, e1004525.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004525
-
-
Rands, C.M.1
-
5
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
5 Roadmap Epigenomics Consortium, et al. Integrative analysis of 111 reference human epigenomes. Nature 518 (2015), 317–330.
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Roadmap Epigenomics Consortium1
-
6
-
-
84899633396
-
Defining functional DNA elements in the human genome
-
6 Kellis, M., et al. Defining functional DNA elements in the human genome. Proc. Natl. Acad. Sci. U.S.A. 111 (2014), 6131–6138.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 6131-6138
-
-
Kellis, M.1
-
7
-
-
84863229330
-
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay
-
7 Melnikov, A., et al. Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay. Nat. Biotechnol. 30 (2012), 271–277.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 271-277
-
-
Melnikov, A.1
-
8
-
-
84964272066
-
Direct identification of hundreds of expression-modulating variants using a multiplexed reporter assay
-
8 Tewhey, R., et al. Direct identification of hundreds of expression-modulating variants using a multiplexed reporter assay. Cell 165 (2016), 1519–1529.
-
(2016)
Cell
, vol.165
, pp. 1519-1529
-
-
Tewhey, R.1
-
9
-
-
84971578930
-
Systematic functional dissection of common genetic variation affecting red blood cell traits
-
9 Ulirsch, J.C., et al. Systematic functional dissection of common genetic variation affecting red blood cell traits. Cell 165 (2016), 1530–1545.
-
(2016)
Cell
, vol.165
, pp. 1530-1545
-
-
Ulirsch, J.C.1
-
10
-
-
84902096048
-
Development and applications of CRISPR–Cas9 for genome engineering
-
10 Hsu, P.D., et al. Development and applications of CRISPR–Cas9 for genome engineering. Cell 157 (2014), 1262–1278.
-
(2014)
Cell
, vol.157
, pp. 1262-1278
-
-
Hsu, P.D.1
-
11
-
-
84928205754
-
High-throughput functional genomics using CRISPR–Cas9
-
11 Shalem, O., et al. High-throughput functional genomics using CRISPR–Cas9. Nat. Rev. Genet. 16 (2015), 299–311.
-
(2015)
Nat. Rev. Genet.
, vol.16
, pp. 299-311
-
-
Shalem, O.1
-
12
-
-
84991382223
-
Genome-scale clustered regularly interspaced short palindromic repeats pooled screens
-
Published online June 1, 2016
-
12 Sanjana, N.E., Genome-scale clustered regularly interspaced short palindromic repeats pooled screens. Anal. Biochem., 2016, 10.1016/j.ab.2016.05.014 Published online June 1, 2016.
-
(2016)
Anal. Biochem.
-
-
Sanjana, N.E.1
-
13
-
-
40349092939
-
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia
-
13 Uda, M., et al. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia. Proc. Natl. Acad. Sci. U.S.A. 105 (2008), 1620–1625.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 1620-1625
-
-
Uda, M.1
-
14
-
-
84946925193
-
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
-
14 Canver, M.C., et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature 527 (2015), 192–197.
-
(2015)
Nature
, vol.527
, pp. 192-197
-
-
Canver, M.C.1
-
15
-
-
84957590341
-
Functional genetic screens for enhancer elements in the human genome using CRISPR–Cas9
-
15 Korkmaz, G., et al. Functional genetic screens for enhancer elements in the human genome using CRISPR–Cas9. Nat. Biotechnol. 34 (2016), 192–198.
-
(2016)
Nat. Biotechnol.
, vol.34
, pp. 192-198
-
-
Korkmaz, G.1
-
16
-
-
84925008880
-
Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis
-
16 Chen, S., et al. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell 160 (2015), 1246–1260.
-
(2015)
Cell
, vol.160
, pp. 1246-1260
-
-
Chen, S.1
-
17
-
-
84957602988
-
High-throughput mapping of regulatory DNA
-
17 Rajagopal, N., et al. High-throughput mapping of regulatory DNA. Nat. Biotechnol. 34 (2016), 167–174.
-
(2016)
Nat. Biotechnol.
, vol.34
, pp. 167-174
-
-
Rajagopal, N.1
-
18
-
-
84994673432
-
High-resolution interrogation of functional elements in the noncoding genome
-
Published online April 18, 2016
-
18 Sanjana, N.E., et al. High-resolution interrogation of functional elements in the noncoding genome. BioRxiv., 2016, 10.1101/049130 Published online April 18, 2016.
-
(2016)
BioRxiv.
-
-
Sanjana, N.E.1
|