Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: Potential contribution to HIV-1 sanctuary site

Journal of Antimicrobial Chemotherapy

Volumn 71, Issue 7, 2016, Pages 1954-1965

  Huang, Yiying ^a   Hoque, Md Tozammel ^a   Jenabian, Mohammad Ali ^b   Vyboh, Kishanda ^c   Whyte, Sana Kay ^a   Sheehan, Nancy L ^d   Brassard, Pierre ^e   Bélanger, Maud ^e   Chomont, Nicolas ^f   Fletcher, Courtney V ^g   Routy, Jean Pierre ^c   Bendayan, Reina ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e Metropolitan Centre of Plastic Surgery   (Canada)

^f CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^g UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; ATAZANAVIR; BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEIN; CELL NUCLEUS RECEPTOR; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DARUNAVIR; DRUG METABOLIZING ENZYME; EFAVIRENZ; EMTRICITABINE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; GLYCOPROTEIN; LAMIVUDINE; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER B; ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1; PERMEABILITY GLYCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREGNANE X RECEPTOR; RITONAVIR; TENOFOVIR; UNCLASSIFIED DRUG; ENZYME; PROTEOME;

ADULT; ANTIVIRAL THERAPY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; GENE EXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; MALE; MIDDLE AGED; PROTEIN EXPRESSION; TANDEM MASS SPECTROMETRY; TESTIS; YOUNG ADULT; BIOTRANSFORMATION; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION PROFILING; METABOLISM; PLASMA;

ADULT; ANTI-RETROVIRAL AGENTS; BIOTRANSFORMATION; CHROMATOGRAPHY, LIQUID; ENZYMES; GENE EXPRESSION PROFILING; HUMANS; MALE; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; PLASMA; PROTEOME; TANDEM MASS SPECTROMETRY; TESTIS; YOUNG ADULT;

EID: 84979034874     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkw046     Document Type: Article

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